**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 91-08-7 |Toluene-2,6-diisocyanate | 97 | 202-039-0 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T+
Risk Phrases: 26 36/37/38 40 42/43 52/53
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Very toxic by inhalation. Irritating to eyes, respiratory system and
skin. Limited evidence of a carcinogenic effect. May cause
sensitization by inhalation and skin contact. Harmful to aquatic
organisms, may cause long-term adverse effects in the aquatic
environment.
Potential Health Effects
Eye:
Causes eye irritation. Lachrymator (substance which increases the
flow of tears).
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Organic isocyanates can cause local irritation and allergic
reactions.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. May cause liver and kidney damage. May cause cardiac
disturbances. May cause central nervous system effects.
Inhalation:
Causes respiratory tract irritation. May cause liver and kidney
damage. Central nervous system effects may include confusion, ataxia
(failure of muscular coordination), vertigo, tinnitus, weakness,
disorientation, lethargy, drowsiness, and finally coma. At high
concentrations, isocyanates affect mucous membranes of the
respiratory tract and may lead to fatal pulmonary edema. Exposure to
low and often even unmeasurable isocyanate concentration results in
sensitization. May cause cardiac damage. Can produce delayed
pulmonary edema.
Chronic:
Repeated or prolonged exposure may cause allergic reactions in
sensitive individuals. Chronic overexposure to isocyanates has been
reported to cause lung damage, including decreased lung fuction,
which may be permanent.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid. Do
NOT allow victim to rub eyes or keep eyes closed.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and
drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing
is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth
resuscitation. If breathing has ceased apply artificial respiration
using oxygen and a suitable mechanical device such as a bag and a
mask.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Vapors may
be heavier than air. They can spread along the ground and collect
in low or confined areas. Containers may explode when heated. Contact
with water forms corrosive vapors. Contact with water liberates
highly flammable gases. Reacts with water, steam or acid to produce
toxic and flammable vapors of hydrogen cyanide. Runoff from fire
control or dilution water may cause pollution.
Extinguishing Media:
Use dry chemical or carbon dioxide.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Clean up spills immediately,
observing precautions in the Protective Equipment section. Provide
ventilation. Do not get water inside containers. Approach spill from
upwind.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Avoid contact with eyes, skin, and clothing. Keep container tightly
closed. Avoid ingestion and inhalation. Use with adequate
ventilation. Do not allow contact with water. Wash clothing before
reuse. Keep from contact with moist air and steam. Isocyanates react
with water to form CO2 gas. This gas can cause sealed containers to
expand and possibly rupture.
Storage:
Store in a tightly closed container. Keep refrigerated. (Store below
4C/39F.) Sometimes packaged under dry nitrogen.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
CAS# 91-08-7:
Germany: 0.005 ppm TWA; 0.035 mg/m3 TWA
Netherlands: 0.02 ppm STEL; 0.15 mg/m3 STEL
Netherlands: 0.005 ppm MAC; 0.04 mg/m3 MAC
Spain: 0.005 ppm VLA-ED; 0.036 mg/m3 VLA-ED
Spain: 0.02 ppm VLA-EC; 0.14 mg/m3 VLA-EC
Personal Protective Equipment
Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: clear, colorless
Odor: None reported.
pH: Not available.
Vapor Pressure: 0.01 mm Hg @ 20 deg C
Viscosity: Not available.
Boiling Point: 246-247 deg C
Freezing/Melting Point: 13 deg C
Autoignition Temperature: Not available.
Flash Point: > 110 deg C (> 230.00 deg F)
Explosion Limits, lower: 0.9%
Explosion Limits, upper: 9.5%
Decomposition Temperature:
Solubility in water: Reacts.
Specific Gravity/Density: 1.22 g/ml
Molecular Formula: C9H6N2O2
Molecular Weight: 174.16
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions. Hazardous polymerization and/or hazardous
decomposition may occur on contact with water or on exposure to
heat.
Conditions to Avoid:
Light, moisture, heat.
Incompatibilities with Other Materials:
Oxidizing agents, acids, strong bases, alcohols, amines, moisture,
organometallic compounds.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, irritating and
toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: May occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 91-08-7: CZ6310000
LD50/LC50:
Not available.
Carcinogenicity:
Toluene-2,6-diisocyanate -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: TOLUENE DIISOCYANATE
Hazard Class: 6.1
UN Number: 2078
Packing Group: II
IMO
Shipping Name: TOLUENE DIISOCYANATE
Hazard Class: 6.1
UN Number: 2078
Packing Group: II
RID/ADR
Shipping Name: TOLUENE DIISOCYANATE
Hazard Class: 6.1
UN Number: 2078
Packing group: II
USA RQ: CAS# 91-08-7: 100 lb final RQ (Listed under Toluene diisocyanate); 45.4
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+
Risk Phrases:
R 26 Very toxic by inhalation.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 40 Limited evidence of a carcinogenic effect.
R 42/43 May cause sensitization by inhalation and
skin contact.
R 52/53 Harmful to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 91-08-7: 2
Canada
CAS# 91-08-7 is listed on Canada's DSL List.
CAS# 91-08-7 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 91-08-7 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 9/02/1997 Revision #9 Date: 7/23/2004
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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|
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| ALL MSDS PAGES IN THIS GROUP
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Dibenz[a,h]anthracene, 99% (UV-Vis)
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Cholesteryl N-Heptylate, 97%
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| 1918-77-0 |
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N-Formylmorpholine, 99+%
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| 98-03-3 |
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1,1-Dimethyl-2-Selenourea, 97%
| 5117-16-8 |
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2-Bromopropionyl chloride, tech.
| 7148-74-5 |
|
Cyclopropanecarboxylic Acid Chloride, 98% (GC)
| 4023-34-1 |
|
Diethyl 3-oxopimelate, 97%
| 40420-22-2 |
|
2,4-Dichlorophenylhydrazine Hydrochloride 99%
| 5446-18-4 |
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| 873-74-5 |
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| 2094-72-6 |
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4-Methoxycinnamonitrile 98% Mixture of Cis/Trans
| 28446-68-6 |
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| 573-57-9 |
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3-Cyclohexylpropionic Acid, 99+%
| 701-97-3 |
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| 50-89-5 |
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| 625-98-9 |
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4-Bromo-2-fluoroaniline, 99%
| 367-24-8 |
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| 74-39-5 |
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| 695-12-5 |
|
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| 2163-48-6 |
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| 42137-88-2 |
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| 288-13-1 |
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1,1-Dimethylcyclohexane, 97%
| 590-66-9 |
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Dimethyl 4,5-imidazoledicarboxylate, 93% (uv-vis)
| 3304-70-9 |
|
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| 5452-37-9 |
|
Tolylene-2,6-Diisocyanate, 97%
| 91-08-7 |
|
3-Fluorophenylhydrazine Hydrochloride 97%
| 2924-16-5 |
|
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| 90-14-2 |
|
L-(+)-Amethopterin hydrate, 99%
| 133073-73-1 |
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| 120-92-3 |
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| 5345-42-6 |
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| 65-46-3 |
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