Search   
MSDS  : dl-Menthol
CAS  : 15356-70-4
SYNONYMS  : * Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1-alpha,2-beta,5-alpha) * 4-Isopropyl-1-methylcyclohexan-3-ol * Menthol, cis-1,3-trans-1,4-(+-)- * (+-)-Menthol * 3-p-Menthol * dl-3-p-Menthanol * Menthol racemic * NCI-C50000 * Menthol racemique
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : OT0525000
CHEMICAL NAME : dl-Menthol
CAS REGISTRY NUMBER : 15356-70-4
BEILSTEIN REFERENCE NO. : 3194263
REFERENCE : 4-06-00-00151 (Beilstein Handbook Reference)
LAST UPDATED : 199701
DATA ITEMS CITED : 19
MOLECULAR FORMULA : C10-H20-O
MOLECULAR WEIGHT : 156.30
WISWESSER LINE NOTATION : L6TJ AY1&1 DQ D1
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
Primary Irritant
SYNONYMS/TRADE NAMES :
* Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1-alpha,2-beta,5-alpha)
* 4-Isopropyl-1-methylcyclohexan-3-ol
* Menthol, cis-1,3-trans-1,4-(+-)-
* (+-)-Menthol
* 3-p-Menthol
* dl-3-p-Menthanol
* Menthol racemic
* NCI-C50000
* Menthol racemique

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 14,473,1976

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1%
REFERENCE :
FRZKAP Farmatsevtichnii Zhurnal (Kiev). (V/O Mezhdunarodnaya Kniga, 113095
Moscow, USSR) V.3- 1930- Volume(issue)/page/year: 17(3),53,1962

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57,
1948-77. Discontinued. Volume(issue)/page/year: 44A,58,1967

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 670 mg/kg
TOXIC EFFECTS :
Behavioral - sleep
Behavioral - hallucinations, distorted perceptions
Behavioral - muscle weakness
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil,
France) V.1- 1943- Volume(issue)/page/year: 10,481,1952

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MMWOAU Muenchener Medicinische Wochenschrift. (Munich, Fed. Rep. Ger.)
V.33-115, 1886-1973. Volume(issue)/page/year: 73,2011,1926

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21,
1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year:
5,233,1932

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 14200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRZKAP Farmatsevtichnii Zhurnal (Kiev). (V/O Mezhdunarodnaya Kniga, 113095
Moscow, USSR) V.3- 1930- Volume(issue)/page/year: 17(3),53,1962

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 14 gm/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory
change
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
REFERENCE :
MMWOAU Muenchener Medicinische Wochenschrift. (Munich, Fed. Rep. Ger.)
V.33-115, 1886-1973. Volume(issue)/page/year: 73,2011,1926

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MMWOAU Muenchener Medicinische Wochenschrift. (Munich, Fed. Rep. Ger.)
V.33-115, 1886-1973. Volume(issue)/page/year: 73,2011,1926

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 1500 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory
change
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
REFERENCE :
MMWOAU Muenchener Medicinische Wochenschrift. (Munich, Fed. Rep. Ger.)
V.33-115, 1886-1973. Volume(issue)/page/year: 73,2011,1926

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 14,473,1976

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57,
1948-77. Discontinued. Volume(issue)/page/year: 44A,58,1967

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 865 mg/kg
TOXIC EFFECTS :
Behavioral - sleep
Behavioral - hallucinations, distorted perceptions
Behavioral - muscle weakness
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil,
France) V.1- 1943- Volume(issue)/page/year: 10,481,1952

** MUTATION DATA **

TYPE OF TEST : DNA damage
TEST SYSTEM : Rodent - rat Liver
DOSE/DURATION : 700 umol/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E.
11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year:
24,181,1994

TYPE OF TEST : Unscheduled DNA synthesis
ROUTE OF EXPOSURE : Oral
TEST SYSTEM : Rodent - rat
DOSE/DURATION : 725 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 320,189,1994

TYPE OF TEST : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE : Oral
TEST SYSTEM : Rodent - mouse
DOSE/DURATION : 1 gm/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 343,157,1995

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X1991
No. of Facilities: 25 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 427 (estimated)
No. of Female Employees: 176 (estimated)

*** STATUS IN U.S. ***

EPA GENETOX PROGRAM 1988, Negative: Carcinogenicity-mouse/rat

NCI Carcinogenesis Bioassay (feed);no evidence:mouse,rat
NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
(Bethesda, MD) No.0-205. For publisher information, see NTPTR*.
Volume(issue)/page/year: NCI-TR-98,79


*** END OF RECORD ***
Search More   
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
para-Menth-1-en-4-ol 562-74-3
p-Menth-1-en-8-ol, (+-)- 2438-12-2
p-Menth-8-en-1-ol 138-87-4
p-Menth-8-en-2-ol 619-01-2
p-Menth-8-en-3-ol 7786-67-6
p-Menth-1-en-8-ol, acetate 80-26-2
Mandelamide, alpha-methyl- 2019-68-3
p-Menth-8-en-2-ol, acetate 20777-49-5
p-Menth-1-en-8-ol, formate (mixed isomers) 2153-26-6
p-Menth-1-en-3-one 89-81-6
p-Menth-4(8)-en-3-one 15932-80-6
p-Menth-4(8)-en-3-one, (R)-(+)- 89-82-7
p-Menth-8-en-2-one 7764-50-3
p-Menth-8-en-3-one, trans- 29606-79-9
L-Methionine, N-(1-oxo-3-phenyl-2-propenyl)-, methylester, (E)- 127750-59-8
Menthol 89-78-1
Menthol, (+)-neo- 63975-60-0
Mandelamide, N-(4-methyl-2-pyridyl)-, hydrochloride 3372-94-9
Menthol, trans-1,3,cis-1,4-, (+)- 63903-52-6
dl-Menthol 15356-70-4
l-Menthol 2216-51-5
Menthol, cis-1,3-cis-1,4-(+-)- 3623-52-7
Menthol, trans-1,3-cis-1,4-(+-)- 3623-51-6
Menthol, isovalerate 16409-46-4
Mentor 28 63148-53-8
Mentzelia decapetala (pursh.) Urb. & Gilg., alkaloidextractSUBSTANCE DEFINITION :Alkaloids obtained from the plant belonging to the family LoasaceaeREFERENCE :JNPRDF Journal of Natural Products. (Spahr & Glenn Co., 225 E. Spring St.,Columbus, OH 43215) V.42- 1979- Volume(issue)/page/year: 44,693,1981 63148-53-8
p-Mercapto sulfadiazine 67479-03-2
Mercurate(1-), acetatophenyl-, ammonium salt 34604-38-1
Mandelamide, N-(5-methyl-2-pyridyl)-, hydrochloride 1086-88-0
Mercurate(1-), (acetato-O)amidophenyl-, hydrogen 53404-67-4
Mercurate(1-), amidophenyl(propanoato-O)-, hydrogen 53404-68-5
Mercurate(4-),bis(N,N-bis(carboxymethyl)glycinato(3-)-N,O,O',O'')-,tetrahydrogen 73128-65-1
Mercurate(1-), butyl(mercaptoacetato(2-)-O,S-),sodium 64048-05-1
Mercurate(1-),(3-(5-carboxylato-1,2-dihydro-2-oxo-1-pyridinyl)-2-methoxypropyl)hydroxy-, sodium, compd. with3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione 7097-62-3
Mercurate(1-)-,(3-(4-(carboxylatomethoxy)phenyl)-2-hydroxypropyl)hydroxy-, sodium 63907-33-5
Mercurate(1-),(3-((((3-carboxylato-1-oxopropyl)amino)carbonyl)amino)-2-methoxypropyl) hydroxy-, sodium, mixed with3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione 8069-64-5
Mercurate(2-), ((cyclohexylenedinitrilo)tetracetato)- 8069-64-5
Mercurate(1-), (L-cysteinato(2-)-S)methyl-, hydrogen 32754-35-1
Mercurate(1-), ethyl(mercaptoacetato(2-)-O,S)-,potassium 64048-06-2
Mandelamide, N-phenyl-alpha-propyl- 39164-86-8
Mercurate(1-), (mercaptoacetato(2-)-O,S)methyl-,sodium 64048-07-3
Mercurate (2-), tetraiodo-, dipotassium 7783-33-7
Mercury 7439-97-6
Mercury, (3-acetamido-2-methoxypropyl)chloro- 7439-97-6
Mercury,acetato(5-(2-amino-2-carboxyethyl)-2-hydroxyphenyl)- 7439-97-6
Mercury, acetato(2-amino-5-carboxyphenyl)- 7439-97-6
Mercury, acetato(4-amino-2-carboxyphenyl)- 7439-97-6
Mercury, acetato(4-amino-3-carboxyphenyl)- 7439-97-6
Mercury, acetato(5-amino-2-hydroxyphenyl)- 7439-97-6
Mercury,(acetato-O)(3-((4-amino-6-methyl-1,3,5-triazin-2-yl)amino)-2-hydroxypropyl )- 7439-97-6

Free MSDS Search ( Providing 250,000+ Material Properties )
Chemcas.com| Ads link:todaystock.net