*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : OU9645000
CHEMICAL NAME : Mercurate(1-),
(3-(5-carboxylato-1,2-dihydro-2-oxo-1-pyridinyl)-2-me
thoxypropyl)hydroxy-, sodium, compd. with
3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
CAS REGISTRY NUMBER : 7097-62-3
LAST UPDATED : 199512
DATA ITEMS CITED : 6
MOLECULAR FORMULA : C10-H13-Hg-N-O5.xC7-H8-N4-O2.xNa
MOLECULAR WEIGHT : 1658.09
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Meragidone sodium
* Merdroxone sodium
* Mergamate sodium
* Therargidone
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 124 mg/kg
TOXIC EFFECTS :
Musculoskeletal - other changes
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 40,394,1951
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 33 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 40,394,1951
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 438 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 40,394,1951
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 124 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Cardiac - other changes
Lungs, Thorax, or Respiration - other changes
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 40,394,1951
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - hamster
DOSE/DURATION : 83 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
Musculoskeletal - other changes
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 40,394,1951
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 661 mg/kg/2W-I
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 40,394,1951
*** END OF RECORD ***
|
|
|
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
para-Menth-1-en-4-ol
| 562-74-3 |
p-Menth-1-en-8-ol, (+-)-
| 2438-12-2 |
p-Menth-8-en-1-ol
| 138-87-4 |
p-Menth-8-en-2-ol
| 619-01-2 |
p-Menth-8-en-3-ol
| 7786-67-6 |
p-Menth-1-en-8-ol, acetate
| 80-26-2 |
Mandelamide, alpha-methyl-
| 2019-68-3 |
p-Menth-8-en-2-ol, acetate
| 20777-49-5 |
p-Menth-1-en-8-ol, formate (mixed isomers)
| 2153-26-6 |
p-Menth-1-en-3-one
| 89-81-6 |
p-Menth-4(8)-en-3-one
| 15932-80-6 |
p-Menth-4(8)-en-3-one, (R)-(+)-
| 89-82-7 |
p-Menth-8-en-2-one
| 7764-50-3 |
p-Menth-8-en-3-one, trans-
| 29606-79-9 |
L-Methionine, N-(1-oxo-3-phenyl-2-propenyl)-, methylester, (E)-
| 127750-59-8 |
Menthol
| 89-78-1 |
Menthol, (+)-neo-
| 63975-60-0 |
Mandelamide, N-(4-methyl-2-pyridyl)-, hydrochloride
| 3372-94-9 |
Menthol, trans-1,3,cis-1,4-, (+)-
| 63903-52-6 |
dl-Menthol
| 15356-70-4 |
l-Menthol
| 2216-51-5 |
Menthol, cis-1,3-cis-1,4-(+-)-
| 3623-52-7 |
Menthol, trans-1,3-cis-1,4-(+-)-
| 3623-51-6 |
Menthol, isovalerate
| 16409-46-4 |
Mentor 28
| 63148-53-8 |
Mentzelia decapetala (pursh.) Urb. & Gilg., alkaloidextractSUBSTANCE DEFINITION :Alkaloids obtained from the plant belonging to the family LoasaceaeREFERENCE :JNPRDF Journal of Natural Products. (Spahr & Glenn Co., 225 E. Spring St.,Columbus, OH 43215) V.42- 1979- Volume(issue)/page/year: 44,693,1981
| 63148-53-8 |
p-Mercapto sulfadiazine
| 67479-03-2 |
Mercurate(1-), acetatophenyl-, ammonium salt
| 34604-38-1 |
Mandelamide, N-(5-methyl-2-pyridyl)-, hydrochloride
| 1086-88-0 |
Mercurate(1-), (acetato-O)amidophenyl-, hydrogen
| 53404-67-4 |
Mercurate(1-), amidophenyl(propanoato-O)-, hydrogen
| 53404-68-5 |
Mercurate(4-),bis(N,N-bis(carboxymethyl)glycinato(3-)-N,O,O',O'')-,tetrahydrogen
| 73128-65-1 |
Mercurate(1-), butyl(mercaptoacetato(2-)-O,S-),sodium
| 64048-05-1 |
Mercurate(1-),(3-(5-carboxylato-1,2-dihydro-2-oxo-1-pyridinyl)-2-methoxypropyl)hydroxy-, sodium, compd. with3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
| 7097-62-3 |
Mercurate(1-)-,(3-(4-(carboxylatomethoxy)phenyl)-2-hydroxypropyl)hydroxy-, sodium
| 63907-33-5 |
Mercurate(1-),(3-((((3-carboxylato-1-oxopropyl)amino)carbonyl)amino)-2-methoxypropyl) hydroxy-, sodium, mixed with3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
| 8069-64-5 |
Mercurate(2-), ((cyclohexylenedinitrilo)tetracetato)-
| 8069-64-5 |
Mercurate(1-), (L-cysteinato(2-)-S)methyl-, hydrogen
| 32754-35-1 |
Mercurate(1-), ethyl(mercaptoacetato(2-)-O,S)-,potassium
| 64048-06-2 |
Mandelamide, N-phenyl-alpha-propyl-
| 39164-86-8 |
Mercurate(1-), (mercaptoacetato(2-)-O,S)methyl-,sodium
| 64048-07-3 |
Mercurate (2-), tetraiodo-, dipotassium
| 7783-33-7 |
Mercury
| 7439-97-6 |
Mercury, (3-acetamido-2-methoxypropyl)chloro-
| 7439-97-6 |
Mercury,acetato(5-(2-amino-2-carboxyethyl)-2-hydroxyphenyl)-
| 7439-97-6 |
Mercury, acetato(2-amino-5-carboxyphenyl)-
| 7439-97-6 |
Mercury, acetato(4-amino-2-carboxyphenyl)-
| 7439-97-6 |
Mercury, acetato(4-amino-3-carboxyphenyl)-
| 7439-97-6 |
Mercury, acetato(5-amino-2-hydroxyphenyl)-
| 7439-97-6 |
Mercury,(acetato-O)(3-((4-amino-6-methyl-1,3,5-triazin-2-yl)amino)-2-hydroxypropyl )-
| 7439-97-6 |
|
|