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MSDS  : p-Menth-4(8)-en-3-one
CAS  : 15932-80-6
SYNONYMS  : * 1-Isopropylidene-4-methyl-2-cyclohexanone * d-p-Menth-4(8)-en-3-one * 4(8)-p-Menthen-3-one * 1-Methyl-4-isopropylidene-3-cyclohexanone
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : OT0260000
CHEMICAL NAME : p-Menth-4(8)-en-3-one
CAS REGISTRY NUMBER : 15932-80-6
LAST UPDATED : 199701
DATA ITEMS CITED : 7
MOLECULAR FORMULA : C10-H16-O
MOLECULAR WEIGHT : 152.26
WISWESSER LINE NOTATION : L6VYTJ BUY1&1 E1
COMPOUND DESCRIPTOR : Primary Irritant
SYNONYMS/TRADE NAMES :
* 1-Isopropylidene-4-methyl-2-cyclohexanone
* d-p-Menth-4(8)-en-3-one
* 4(8)-p-Menthen-3-one
* 1-Methyl-4-isopropylidene-3-cyclohexanone

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Moderate
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 16,867,1978

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 470 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 16,867,1978

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: AD691-490

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1709 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 16,867,1978

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 3090 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 16,867,1978

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4480 mg/kg/28D-I
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes
Blood - changes in other cell count (unspecified)
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 19,207,1983

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY


*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
para-Menth-1-en-4-ol 562-74-3
p-Menth-1-en-8-ol, (+-)- 2438-12-2
p-Menth-8-en-1-ol 138-87-4
p-Menth-8-en-2-ol 619-01-2
p-Menth-8-en-3-ol 7786-67-6
p-Menth-1-en-8-ol, acetate 80-26-2
Mandelamide, alpha-methyl- 2019-68-3
p-Menth-8-en-2-ol, acetate 20777-49-5
p-Menth-1-en-8-ol, formate (mixed isomers) 2153-26-6
p-Menth-1-en-3-one 89-81-6
p-Menth-4(8)-en-3-one 15932-80-6
p-Menth-4(8)-en-3-one, (R)-(+)- 89-82-7
p-Menth-8-en-2-one 7764-50-3
p-Menth-8-en-3-one, trans- 29606-79-9
L-Methionine, N-(1-oxo-3-phenyl-2-propenyl)-, methylester, (E)- 127750-59-8
Menthol 89-78-1
Menthol, (+)-neo- 63975-60-0
Mandelamide, N-(4-methyl-2-pyridyl)-, hydrochloride 3372-94-9
Menthol, trans-1,3,cis-1,4-, (+)- 63903-52-6
dl-Menthol 15356-70-4
l-Menthol 2216-51-5
Menthol, cis-1,3-cis-1,4-(+-)- 3623-52-7
Menthol, trans-1,3-cis-1,4-(+-)- 3623-51-6
Menthol, isovalerate 16409-46-4
Mentor 28 63148-53-8
Mentzelia decapetala (pursh.) Urb. & Gilg., alkaloidextractSUBSTANCE DEFINITION :Alkaloids obtained from the plant belonging to the family LoasaceaeREFERENCE :JNPRDF Journal of Natural Products. (Spahr & Glenn Co., 225 E. Spring St.,Columbus, OH 43215) V.42- 1979- Volume(issue)/page/year: 44,693,1981 63148-53-8
p-Mercapto sulfadiazine 67479-03-2
Mercurate(1-), acetatophenyl-, ammonium salt 34604-38-1
Mandelamide, N-(5-methyl-2-pyridyl)-, hydrochloride 1086-88-0
Mercurate(1-), (acetato-O)amidophenyl-, hydrogen 53404-67-4
Mercurate(1-), amidophenyl(propanoato-O)-, hydrogen 53404-68-5
Mercurate(4-),bis(N,N-bis(carboxymethyl)glycinato(3-)-N,O,O',O'')-,tetrahydrogen 73128-65-1
Mercurate(1-), butyl(mercaptoacetato(2-)-O,S-),sodium 64048-05-1
Mercurate(1-),(3-(5-carboxylato-1,2-dihydro-2-oxo-1-pyridinyl)-2-methoxypropyl)hydroxy-, sodium, compd. with3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione 7097-62-3
Mercurate(1-)-,(3-(4-(carboxylatomethoxy)phenyl)-2-hydroxypropyl)hydroxy-, sodium 63907-33-5
Mercurate(1-),(3-((((3-carboxylato-1-oxopropyl)amino)carbonyl)amino)-2-methoxypropyl) hydroxy-, sodium, mixed with3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione 8069-64-5
Mercurate(2-), ((cyclohexylenedinitrilo)tetracetato)- 8069-64-5
Mercurate(1-), (L-cysteinato(2-)-S)methyl-, hydrogen 32754-35-1
Mercurate(1-), ethyl(mercaptoacetato(2-)-O,S)-,potassium 64048-06-2
Mandelamide, N-phenyl-alpha-propyl- 39164-86-8
Mercurate(1-), (mercaptoacetato(2-)-O,S)methyl-,sodium 64048-07-3
Mercurate (2-), tetraiodo-, dipotassium 7783-33-7
Mercury 7439-97-6
Mercury, (3-acetamido-2-methoxypropyl)chloro- 7439-97-6
Mercury,acetato(5-(2-amino-2-carboxyethyl)-2-hydroxyphenyl)- 7439-97-6
Mercury, acetato(2-amino-5-carboxyphenyl)- 7439-97-6
Mercury, acetato(4-amino-2-carboxyphenyl)- 7439-97-6
Mercury, acetato(4-amino-3-carboxyphenyl)- 7439-97-6
Mercury, acetato(5-amino-2-hydroxyphenyl)- 7439-97-6
Mercury,(acetato-O)(3-((4-amino-6-methyl-1,3,5-triazin-2-yl)amino)-2-hydroxypropyl )- 7439-97-6

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