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MSDS  : 2,7-Naphthalenedisulfonic acid, 3-hydroxy-4-((4-sulfo-1-naphthalenyl)azo)-, trisodium salt
CAS  : 2611-82-7
SYNONYMS  : * Acidal Bright Ponceau 3R * Acid Brilliant Scarlet 3R * Acid Ponceau 4R * Acid Red 18 * Acid Scarlet 3R * Acid Scarlet 4R * Acid Scarlet 3RZ * Acilan Scarlet V3R * Aizen Brilliant Scarlet 3RH * Atul Acid Scarlet 3R * Atul Scarlet F * Brilliant Ponceau 3R * Brilliant Ponceau 4R * Brilliant Ponceau 5R * Brilliant Ponceau 4RC * Brilliant Ponceau 4RC Specially Pure * Brilliant Ponceau 3RF * Brilliant Scarlet * Brilliant Scarlet 3R * Brilliant Scarlet 4R * Bucacid Brilliant Scarlet 3R * Calcocid Brilliant Scarlet 3RN * Certicol Ponceau 4RS * Cerven kosenilova A * Cerven kysela 18 * Cerven potravinarska 7 * Cilefa Ponceau 4R * Coccine * Coccine nouvelle * Coccin Red * Cochenillerot A * Cochineal Red A * Cochineal Red A Specially Pure * Cochineal Red 4R * Colacid Ponceau 4R * C.I. 185 * C.I. 16255 * C.I. Acid Red 18 * C.I. Acid Red 18, trisodium salt * C.I. Food Red 7 * Crimson SX * Curol Bright Red 4R * Daishiki Brilliant Scarlet 3R * E 124 * Edicol Supra Ponceau 4R * Eurocert Cochineal Red A * Fenazo Scarlet 3R * Food Red 6 * Food Red 7 * Food Red No. 102 * HD Ponceau 4R * HD Ponceau 4R Supra * Hexacol Ponceau 4R * Hidacid Fast Scarlet 3R * Hispacid Brilliant Scarlet 3RF * Java Scarlet 3R * Kayaku Acid Brilliant Scarlet 3R * Kayaku Food Colour Red No. 102 * Kiton Scarlet 4R * Kochineal Red A for food * L-Rot 4 * Naphthalene Ink Scarlet 4R * Naphthalene Scarlet 4R * Naphthalene Scarlet 4RS * Neklacid Red 3R * Neklacid Red 4R * Neucoccin * New coccin * New coccine * New Coccine Extra Conc. A Export * New Coccine Extra Pure A * Ponceau 4R * Ponceau 4R Aluminum Lake * Ponceau 4RE * Ponceau 4RE.FQ * Ponceau 4RF * Ponceau 4RT * Pontacyl Scarlet RR * Purple Red * Purple SX * Rakuto Brilliant Scarlet 3R * 1578 Red * Rouge de cochenille A * San-ei Brilliant Scarlet 3R * Schultz Nr. 213 * Strawberry Red A Geigy * Sugai Brilliant Scarlet 3R * 1-(4-Sulpho-1-naphthylazo)-2-naphthol-6,8-disulphonic acid, trisodium salt * SX purple * Symulon Acid Brilliant Scarlet 3R * Takaoka Brilliant Scarlet 3R * Victoria Scarlet 3R * Victoria Scarlet Red * Victoria Scharlach 4 R Extra
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : QJ6530000
CHEMICAL NAME : 2,7-Naphthalenedisulfonic acid,
3-hydroxy-4-((4-sulfo-1-naphthalenyl)azo)-, trisodium
salt
CAS REGISTRY NUMBER : 2611-82-7
OTHER CAS REGISTRY NOS. : 39470-82-1
LAST UPDATED : 199709
DATA ITEMS CITED : 16
MOLECULAR FORMULA : C20-H14-N2-O10-S3.3Na
MOLECULAR WEIGHT : 607.51
WISWESSER LINE NOTATION : L66J CO HSWO JSWO BNUN- BL66J ESWO &-NA- 4
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* Acidal Bright Ponceau 3R
* Acid Brilliant Scarlet 3R
* Acid Ponceau 4R
* Acid Red 18
* Acid Scarlet 3R
* Acid Scarlet 4R
* Acid Scarlet 3RZ
* Acilan Scarlet V3R
* Aizen Brilliant Scarlet 3RH
* Atul Acid Scarlet 3R
* Atul Scarlet F
* Brilliant Ponceau 3R
* Brilliant Ponceau 4R
* Brilliant Ponceau 5R
* Brilliant Ponceau 4RC
* Brilliant Ponceau 4RC Specially Pure
* Brilliant Ponceau 3RF
* Brilliant Scarlet
* Brilliant Scarlet 3R
* Brilliant Scarlet 4R
* Bucacid Brilliant Scarlet 3R
* Calcocid Brilliant Scarlet 3RN
* Certicol Ponceau 4RS
* Cerven kosenilova A
* Cerven kysela 18
* Cerven potravinarska 7
* Cilefa Ponceau 4R
* Coccine
* Coccine nouvelle
* Coccin Red
* Cochenillerot A
* Cochineal Red A
* Cochineal Red A Specially Pure
* Cochineal Red 4R
* Colacid Ponceau 4R
* C.I. 185
* C.I. 16255
* C.I. Acid Red 18
* C.I. Acid Red 18, trisodium salt
* C.I. Food Red 7
* Crimson SX
* Curol Bright Red 4R
* Daishiki Brilliant Scarlet 3R
* E 124
* Edicol Supra Ponceau 4R
* Eurocert Cochineal Red A
* Fenazo Scarlet 3R
* Food Red 6
* Food Red 7
* Food Red No. 102
* HD Ponceau 4R
* HD Ponceau 4R Supra
* Hexacol Ponceau 4R
* Hidacid Fast Scarlet 3R
* Hispacid Brilliant Scarlet 3RF
* Java Scarlet 3R
* Kayaku Acid Brilliant Scarlet 3R
* Kayaku Food Colour Red No. 102
* Kiton Scarlet 4R
* Kochineal Red A for food
* L-Rot 4
* Naphthalene Ink Scarlet 4R
* Naphthalene Scarlet 4R
* Naphthalene Scarlet 4RS
* Neklacid Red 3R
* Neklacid Red 4R
* Neucoccin
* New coccin
* New coccine
* New Coccine Extra Conc. A Export
* New Coccine Extra Pure A
* Ponceau 4R
* Ponceau 4R Aluminum Lake
* Ponceau 4RE
* Ponceau 4RE.FQ
* Ponceau 4RF
* Ponceau 4RT
* Pontacyl Scarlet RR
* Purple Red
* Purple SX
* Rakuto Brilliant Scarlet 3R
* 1578 Red
* Rouge de cochenille A
* San-ei Brilliant Scarlet 3R
* Schultz Nr. 213
* Strawberry Red A Geigy
* Sugai Brilliant Scarlet 3R
* 1-(4-Sulpho-1-naphthylazo)-2-naphthol-6,8-disulphonic acid, trisodium
salt
* SX purple
* Symulon Acid Brilliant Scarlet 3R
* Takaoka Brilliant Scarlet 3R
* Victoria Scarlet 3R
* Victoria Scarlet Red
* Victoria Scharlach 4 R Extra

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >8 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 5,187,1967

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 600 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Behavioral - coma
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 5,187,1967

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SCPHA4 Scientia Pharmaceutica. (Oesterreichische
Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria)
V.1- 1930- Volume(issue)/page/year: 47,39,1979

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NAIZAM Nara Igaku Zasshi. Journal of the Nara Medical Association. (Nara
Igakkai, c/o Narakenritsu Ika Daigaku, Shijo-cho, Kashihara, Nara-ken,
Japan) V.1- 1950- Volume(issue)/page/year: 30,179,1979

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 8 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SCPHA4 Scientia Pharmaceutica. (Oesterreichische
Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria)
V.1- 1930- Volume(issue)/page/year: 47,39,1979

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1600 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Behavioral - coma
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 5,187,1967

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 143 gm/kg/90D-C
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - transaminases
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 5,187,1967

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 30 gm/kg/30D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Kidney, Ureter, Bladder - other changes in urine composition
REFERENCE :
TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479,
Russia) History Unknown Volume(issue)/page/year: (2),34,1996

TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 48 mg/m3/17W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - structural or functional change in trachea
or bronchi
Liver - liver function tests impaired
Blood - other changes
REFERENCE :
TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479,
Russia) History Unknown Volume(issue)/page/year: (2),34,1996

** TUMORIGENIC DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 428 gm/kg/64W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Liver - tumors
REFERENCE :
VPITAR Voprosy Pitaniya. Problems of Nutrition. (V/O Mezhdunarodnaya
Kniga, 113095 Moscow, USSR) V.1-10, 1932-41; V.11- 1952-
Volume(issue)/page/year: 29,61,1970

** MUTATION DATA **

TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Rodent - hamster Fibroblast
DOSE/DURATION : 1 gm/L
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
22,623,1984

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M4494
No. of Facilities: 46 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 138 (estimated)

NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M4494
No. of Facilities: 1035 (estimated)
No. of Industries: 5
No. of Occupations: 9
No. of Employees: 8379 (estimated)
No. of Female Employees: 2006 (estimated)

*** STATUS IN U.S. ***

EPA GENETOX PROGRAM 1988, Negative: S cerevisiae gene conversion

EPA GENETOX PROGRAM 1988, Inconclusive: B subtilis rec assay

EPA TSCA Section 8(b) CHEMICAL INVENTORY


*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy- 90-20-0
2,7-Naphthalenedisulfonic acid, 4-amino-3-hydroxy-,disodium salt 42579-07-7
2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-,disodium salt 3963-80-2
1,3-Naphthalenedisulfonic acid,4-amino-5-hydroxy-6-((4'-((2-hydroxy-1-naphthalenyl)azo)-3,3'-dimethoxy(1, 1'-biphenyl)-4-yl)azo)-,disodium salt 2586-57-4
2,7-Naphthalenedisulfonic acid,4-amino-5-hydroxy-6-((4'-((4-hydroxyphenyl)azo)(1,1'-biphenyl)-4-yl)azo)-3-((4-nitrophenyl)azo)-,disodium salt 4335-09-5
2,6-Naphthalenedisulfonic acid,4-amino-5-hydroxy-3-((4'-((4-hydroxyphenyl)azo)(1,1'-biphenyl)-4-yl)azo)-6-(phenylazo)-, disodium salt 3626-28-6
2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-,2-(4-nicotinoyl-1-piperazinyl) ethyl ester,dihydrochloride, (S)- 97699-66-6
2,7-Naphthalenedisulfonic acid,4-amino-5-hydroxy-3-((4-nitrophenyl)azo)-6-(phenylazo)-, disodium salt 1064-48-8
2,7-Naphthalenedisulfonic acid,4-amino-5-hydroxy-6-phenylazo-, disodium salt 3567-66-6
3,6-Naphthalenedisulfonic acid, 8-amino-7-hydroxy-,sodium salt 2007-20-7
2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-,p-toluenesulfonate (ester) 6837-93-0
2,7-Naphthalenedisulfonic acid,3-amino-4-((4'-((4-(((4-methylphenyl)sulfonyl)oxy)phenyl) azo)(1,1'-biphenyl)-4-yl)azo)-, disodium salt 2429-80-3
2,7-Naphthalenedisulfonic acid,4-((4-anilino-5-sulfo-1-naphthyl)azo)-5-hydroxy-,trisodium salt 3861-73-2
2,7-Naphthalenedisulfonic acid,3,3'-((4,4'-biphenylylene)bis(azo))bis(5-amino-4-hydroxy-, tetrasodium salt 2602-46-2
1,5-Naphthalenedisulfonic acid,3-((p-(bis(2-chloroethyl)amino)phenyl)azo)- 101931-20-8
2,7-Naphthalenedisulfonic acid,3,6-(bis(4-((2-hydroxyethyl)sulfonyl)phenyl)bis(azo))- 5-amino-4-hydroxy-, di(hydrogen sulfate) ester,tetrasodium salt 17095-24-8
1,3-Naphthalenedisulfonic acid,7-(3-(p-butoxyphenyl)-2-thioureido)-, dipotassiumsalt 37556-92-6
2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-,2-(4-(1-oxo-3-phenyl-2-propenyl)-1- piperazinyl)ethylester, monohydrochloride, (S)- 97699-78-0
1,5-Naphthalenedisulfonic acid,3-(3-(p-butoxyphenyl)-2-thioureido)-, disodium salt 37556-91-5
2,7-Naphthalenedisulfonic acid,4-(2-carboxyphenylazo)-3-hydroxy-, trisodium salt 1836-22-2
2,7-Naphthalenedisulfonic acid,4-(4-chloro-6-ethylphenylamino-2-s-triazinylamino)-5-hydroxy-6-(4-methyl-2-sulfophenylazo)-, trisodiumsalt 73816-74-7
2,7-Naphthalenedisulfonic acid,5-((4-chloro-6-(phenylamino)-1,3,5-triazin-2-yl)amino)-4- hydroxy-3-((2-sulfophenyl)azo)-, trisodium salt 23211-47-4
1,5-Naphthalenedisulfonic acid, 3,?-diamino- 39699-08-6
3,6-Naphthalenedisulfonic acid,1,7-diamino-8-hydroxy- 3545-88-8
2,6-Naphthalenedisulfonic acid, 3,7-di-tert-butyl-,compd. with 6-(dimethylamino)-4,4-diphenyl-3-hexanone 103442-82-6
2,7-Naphthalenedisulfonic acid,3,3'-((3,3'-dichloro-4,4'-biphenylylene)bis(azo))bis(5-amino-4-hydroxy-, tetrasodium salt 47897-65-4
2,7-Naphthalenedisulfonic acid,4-(4,6-dichloro-s-triazin-2-ylamino)-5-hydroxy-6-(2-hydroxy- 5-nitrophenylazo)- 73826-58-1
2,7-Naphthalenedisulfonic acid,5-(3,5-dichloro-s-triazinylamino)-4-hydroxy-3-phenylazo- 6522-86-7
2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-,2-(4-phenyl-1-piperazinyl)ethyl ester, (S)- 97699-76-8
2,7-Naphthalenedisulfonic acid,5-((4,6-dichloro-s-triazin-2-yl)amino)-4-hydroxy-3-(phenylazo)-, disodium salt 17804-49-8
1,5-Naphthalenedisulfonic acid,2-(6-(4,6-dichloro-s-triazinyl)methylamino-1-hydroxy-3- sulfonaphthylazo)- 73816-75-8
2,7-Naphthalenedisulfonic acid,4,5-dihydroxy-3-(phenylazo)-, disodium salt 4197-07-3
2,7-Naphthalenedisulfonic acid,3,3'-((3,3'-dimethoxy-4,4'-biphenylylene)bis(azo))bis( 5-amino-4-hydroxy-, tetrasodium salt 2429-74-5
6,8-Naphthalenedisulfonic acid,3,3'-((3,3'-dimethoxy-4,4'-biphenylene)bis(azo))bis(5-amino-4-hydroxy-, tetrasodium salt 2610-05-1
1,3-Naphthalenedisulfonic acid,6,6'-((3,3'-dimethyl-4,4'-biphenylylene)bis(azo))bis(4-amino-5-hydroxy-, tetrasodium salt 314-13-6
2,7-Naphthalenedisulfonic acid,3,3'-((3,3'-dimethyl-4,4'-biphenylylene)bis(azo))bis(5- amino-4-hydroxy-, tetrasodium salt 72-57-1
1,3-Naphthalenedisulfonic acid,8-((3,3'-dimethyl-4'-((4-(((4-methylphenyl)sulfonyl)oxy) phenyl)azo)(1,1'-biphenyl)-4-yl)azo)-7-hydroxy-,disodium salt 6459-94-5
1,3-Naphthalenedisulfonic acid,8-((4'-((4-ethoxyphenyl)azo)-3,3'-dimethyl(1,1'-biphenyl)-4- yl)azo)-7-hydroxy-, disodium salt 6358-29-8
1,3-Naphthalenedisulfonic acid, 7-hydroxy-, disodiumsalt 842-19-3
2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-,(1,4-piperazinediyl)diethylene ester, (S-(R*,R*))- 97699-69-9
2,7-Naphthalenedisulfonic acid, 3-hydroxy-, disodiumsalt 135-51-3
2,7-Naphthalenedisulfonic acid,4-hydroxy-3-((4'-((2-hydroxy-1-naphthalenyl)azo)-2,2'- dimethyl(1,1'-biphenyl)-4-yl)azo)-, disodium salt 3701-40-4
2,6-Naphthalenedisulfonic acid,4-hydroxy-3-((2-methoxy-5-methylphenyl)azo)-,disodium salt 5864-85-7
1,3-Naphthalenedisulfonic acid,7-hydroxy-8-((4'-((4-(((4-methylphenyl)sulfonyl)oxy)phenyl) azo)(1,1'-biphenyl)-4-yl)azo)-, disodium salt 3567-65-5
2,7-Naphthalenedisulfonic acid,3-hydroxy-4-(1-naphthalenylazo)-, disodium salt 5858-33-3
2,7-Naphthalenedisulfonic acid, 3-hydroxy-4-nitroso-,disodium salt 525-05-3
2-Naphthalenesulfonic acid,4-hydroxy-3-((3-nitro-5-sulfophenyl)azo)-6-((3-((4-nitrophenyl) azo)-4,6-dihydroxyphenyl)azo)-, disodiumsalt 525-05-3
1,3-Naphthalenedisulfonic acid,7-hydroxy-8-(phenylazo)-, disodium salt 1936-15-8
2,7-Naphthalenedisulfonic acid,3-hydroxy-4-((4-sulfo-1-naphthalenyl)azo)-, trisodiumsalt 2611-82-7
2,7-Naphthalenedisulfonic acid,3-hydroxy-4-((4-sulfo-1-naphthyl)azo)-, trisodiumsalt 915-67-3

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