1,3-Naphthalenedisulfonic acid,
8-((3,3'-dimethyl-4'-((4-(((4-methylphenyl)sulfonyl)o
xy) phenyl)azo)(1,1'-biphenyl)-4-yl)azo)-7-hydroxy-,
disodium salt
CAS  
:
6459-94-5
SYNONYMS  
:
* Acid Leather Red BG
* Acid Red 114
* Amacid Milling Red PRS
* Benzyl Fast Red BG
* Benzyl Red BR
* Cerven kysela 114
* C.I. 23635
* C.I. Acid Red 114
* C.I. Acid Red 114, disodium salt
* Elcacid Milling Fast Red RS
* Erionyl Red RS
* Fenafor Red PB
* Folan Red B
* Intrazone Red BR
* Kayanol Milling Red RS
* Leather Fast Red B
* Levanol Red GG
* Midlon Red PRS
* Milling Fast Red B
* Milling Red B
* Milling Red BB
* Milling Red SWB
* NCI C61096
* Polar Red RS
* Sandolan Red N-RS
* Sella Fast Red RS
* Sulphonol Fast Red R
* Sulphonol Red R
* Suminol Milling Red RS
* Supranol Fast Red 3G
* Supranol Fast Red GG
* Supranol Red PBX-CF
* Supranol Red R
* Telon Fast Red GG
* Tetracid Milling Red B
* Tetracid Milling Red G
* Vondamol Fast Red RS
*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : QJ6475500
CHEMICAL NAME : 1,3-Naphthalenedisulfonic acid,
8-((3,3'-dimethyl-4'-((4-(((4-methylphenyl)sulfonyl)o
xy) phenyl)azo)(1,1'-biphenyl)-4-yl)azo)-7-hydroxy-,
disodium salt
CAS REGISTRY NUMBER : 6459-94-5
LAST UPDATED : 199710
DATA ITEMS CITED : 14
MOLECULAR FORMULA : C37-H28-N4-O10-S3.2Na
MOLECULAR WEIGHT : 830.85
WISWESSER LINE NOTATION : L66J BNUNR B1 DR C1 DNUNR DOSWR D1&&&& CQ HSWO JSWO
&-NA- 2
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* Acid Leather Red BG
* Acid Red 114
* Amacid Milling Red PRS
* Benzyl Fast Red BG
* Benzyl Red BR
* Cerven kysela 114
* C.I. 23635
* C.I. Acid Red 114
* C.I. Acid Red 114, disodium salt
* Elcacid Milling Fast Red RS
* Erionyl Red RS
* Fenafor Red PB
* Folan Red B
* Intrazone Red BR
* Kayanol Milling Red RS
* Leather Fast Red B
* Levanol Red GG
* Midlon Red PRS
* Milling Fast Red B
* Milling Red B
* Milling Red BB
* Milling Red SWB
* NCI C61096
* Polar Red RS
* Sandolan Red N-RS
* Sella Fast Red RS
* Sulphonol Fast Red R
* Sulphonol Red R
* Suminol Milling Red RS
* Supranol Fast Red 3G
* Supranol Fast Red GG
* Supranol Red PBX-CF
* Supranol Red R
* Telon Fast Red GG
* Tetracid Milling Red B
* Tetracid Milling Red G
* Vondamol Fast Red RS
*** HEALTH HAZARD DATA ***
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 26 gm/kg/13D-C
TOXIC EFFECTS :
Endocrine - changes in thymus weight
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NPT-TR-405,1991
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 10920 mg/kg/13W-C
TOXIC EFFECTS :
Liver - changes in liver weight
Kidney, Ureter, Bladder - changes in bladder weight
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - transaminases
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-405,1991
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 15 mg/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Sense Organs and Special Senses (Olfaction) - tumors
Skin and Appendages - tumors
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research
Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-405,1991
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 300 nmol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 136,33,1984
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 125 ug/plate
REFERENCE :
VHTODE Veterinary and Human Toxicology. (American College of Veterinary and
Comparative Toxicology, Publication Office, Comparative Toxicology,
Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 22,413,1980
*** REVIEWS ***
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 57,247,1993
IARC Cancer Review:Human Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 57,247,1993
IARC Cancer Review:Group 2B
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 57,247,1993
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M1427
No. of Facilities: 116 (estimated)
No. of Industries: 3
No. of Occupations: 14
No. of Employees: 2855 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M1427
No. of Facilities: 331 (estimated)
No. of Industries: 9
No. of Occupations: 12
No. of Employees: 18511 (estimated)
No. of Female Employees: 352 (estimated)