LIFE TECHNOLOGIES -- OPD (O-PHENYLENEDIAMINE DIHYDROCHLORIDE), 159
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Material Safety Data Sheet
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MSDS Num: CJVFY
MSDS NAME: OPD (O-PHENYLENEDIAMINE DIHYDROCHLORIDE), 15974
Responsible Party
Name: LIFE TECHNOLOGIES
Address: 335 EXECUTIVE WAY
City: FREDERICK MD 21704
Info Phone: 800-828-6686
Emergency Phone Number: 301-431-8585
Resp. Party Other MSDS No.: 15974
Review Ind: Y
Published: Y
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Contractor Summary
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Name: LIFE TECHNOLOGIES INC
Box: 68
City: GRAND ISLAND NY 14072
Phone: 800-828-6686
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Item Description Information
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Ingredients
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Cas: 615-28-1
RTECS #: ST0175000
Name: O-PHENYLENEDIAMINE, DIHYDROCHLORIDE
Percent by Wt: 100.
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Health Hazards Data
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LD50 LC50 Mixture: SEE TOXICOLOGICAL INFO
Route Of Entry Inds - Inhalation: YES
Skin: NO
Ingestion: YES
Carcinogenicity Inds - NTP: NO
IARC: NO
OSHA: NO
Effects of Exposure: ACUTE EFFECTS: FROM EYE EXPOSURE: MAY CAUSE PAIN IN EYE.
MAY CAUSE IRRITATION OF EYE. MAY CAUSE CONJUNCTIVITIS. FROM SKIN
OVEREXPOSURE: CONTACT WITH SOLID MAY IRRITATE/INFLAME SKIN. MAY CAUSE REDNESS
(ERYTHEMATOUS). FROM INHALATION: MAY CAUSE NASAL IRRITATION. MAY CAUSE
RESPIRATORY TRACT IRRITATION. MAY CAUSE COUGHING. MAY CAUSE CHEST PAIN. MAY
CAUSE BREATHING DIFFICULTY, WHEEZING OR SHORTNESS/BLO CKAGE OF BREATH
(DYSPNEA). FROM INGESTION: MAY BE HARMFUL IF SWALLOWED. MAY CAUSE NAUSEA
AND/OR VOMITING. MAY BE ABSORBED IN THE GASTROINTESTINAL TRACT IN TOXIC
QUANTITIES. OTHER/SYSTEMIC EFFECTS: (EF FECTS OF OVEREXPOSURE)
Signs And Symptions Of Overexposure: HEALTH HAZARDS. MAY CAUSE HEADACHE. MAY
CAUSE WEAKNESS. MAY CAUSE NAUSEA. MAY CAUSE CHANGES IN THE RESULTS OF COMMON
CLINICAL URINE TESTS. A CONSTITUENT(S) OF THIS PRODUCT IS KNOWN TO PRODUCE AN
ELEVA TED INCIDENCE OF HYPERSENSITIVITY IN HUMANS. MAY CAUSE ALLERGIC
ANAPHYLAXIS.
Medical Cond Aggravated By Exposure: PRE-EXISTING SKIN DISORDERS. RENAL
INSUFFICIENCY. HEPATIC INSUFFICIENCY. ALLERGY OR HYPERSENSITIVY TO: AMINES.
First Aid: EYES: FLUSH W/WATER IN EYEWASH FOR AT LEAST 15 MIN, HOLDING EYELIDS
OPEN. OBTAIN MED ATTN UNLESS EFTS ARE MILD & TEMPORARY. SKIN: USE DELUGE
SFTY SHOWER FOR AT LEAST 15 MIN. WASH W/PLENTY OF SOAP & WA TER. REMOVE
CONTAM CLOTHES, WASH BEFORE REUSE. BE ALERT TO EARLY INDICATIONS OF ALLERGIC
RXNS OR HYPERSENS. MOST EXPOSURES DO NOT REQ MED ATTN. INHAL: REMOVE PERSON
TO FRESH AIR. MONITOR CONTINUOUSLY FOR RESP DISTRESS. BE ALERT TO EARLY
INDICATIONS OF ALLERGIC RXNS OR HYPERSENS. OVEREXP CAN BE DANGEROUS. GET EMER
MED ATTN. INGEST: GIVE PLENTY OF WATER, IF CONSCIOUS. IF VOMIT OCCURS
NATURALLY, WASH MOUTH OUT. BE ALERT TO EARLY (SUPDAT)
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Handling and Disposal
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Spill Release Procedures: NOTE:ACCIDENTAL RELS MAY BE SUBJECT TO SPEC REPORTING
REQS & OTHER REGULATORY MANDATES. CHECK & COMPLY W/APPLIC LAWS &
REGS. REMOVE/SHUT OFF IGNIT SOURCES. VENT AREA. SWEEP GENTLY TO AVOID
GENERATING DUST. FLUSH AREA W/WATER. ABSORB SPILL USING FOLLOWING MATLS:
MOST ABSORB MATLS SHOULD BE EFTIVE. ALTERNATIVE: SPEC VACUUM CLEANER EQUIPPED
FOR PURPOSE OF HAVING HEPA FILTERED DISCHARGE (OTHER INFO)
Waste Disposal Methods: KEEP IN SEALED CNTNR BETWEEN USE & FINAL DISP. PROD
IS NOT RECYCLABLE OR REUSABLE. MAY BE INCIN IN TYPICAL TRASH INCINERATORS.
MAY BE INCIN IN HAZ WASTE INCINERATOR. PROD IS COMPAT W/TYPICAL LANDFILL
DISP IF NO OTHER METH AVAIL. PROD SHOULD BE REMOVED TO HAZ WASTE LANDFILL
ONLY IF NO OTHER DISP METH IS AVAIL. EPA WASTE # (RCRA HAZ (SARA REG INFO)
Handling And Storage Precautions: STORAGE OF SOME MATLS IS REGULATED; IT IS
PURCHASER'S RESPONSIBILITY TO ENSURE THAT STORAGE COMPLIES W/ALL APPLIC LAWS
& REGS. STORAGE TEMP: FROZEN (<-5C). STORAGE PRESS: ATMOSPHERIC. STORE
IN DRY ARE A. SUITABLE FOR MOST GENERAL CHEMICAL STORAGE AREAS. EMPTY
CONTAINERS MAY BE HAZARDOUS.
Other Precautions: USE IN MINIMAL QUANTITIES. CONTACT LENSES SHOULD NOT BE
WORN. AVOID GENERATING DUST.
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Fire and Explosion Hazard Information
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Flash Point Text: SUPDAT
Autoignition Temp Text: SUPDAT
Extinguishing Media: USE MEANS APPROPRIATE FOR SURROUNDING MATERIALS.
Fire Fighting Procedures: USE NIOSH APPROVED SCBA AND FULL PROTECTIVE EQUIPMENT
(FP N).
Unusual Fire/Explosion Hazard: COMBUSTIBLE. DUST MAY BE FLAMMABLE. DUST MAY BE
EXPLOSIVE. THE PRODUCT QUANTITY SOLD IS NOT EXPECTED TO BE A SIGNIFICANT
COMBUSTION HAZARD.
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Control Measures
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Respiratory Protection: AIR PURIFYING RESPIRATOR CANISTERS/CARTRIDGES: DUSTS,
FUMES AND MISTS (RED OR GRAY STRIPE ANSI COLOR CODE, NIOSH APPROVED).
HEPA-TYPE DUSTS/RADIONUCLIDES (MAGENTA ANSI COLOR CODE, NIOSH APPROVED).
Ventilation: LOCAL EXHAUST PROPERLY USED AT SOURCE OF AIRBORNE GENERATION
GENERALLY PROVIDES THE BEST CONTROL. LAB EXHAUST HOOD OR LOCAL EXHAUST SHOULD
BE USED.
Protective Gloves: ANY WATERPROOF MATERIAL. ANY RUBBER MATERIAL.
Eye Protection: ANSI APPROVED CHEMICAL WORKERS GOGGLES (FP N).
Other Protective Equipment: EYE WASH AND DELUGE SHOWER MEETING ANSI DESIGN
CRITERIA (FP N). PROTECTIVE CLOTHING: ANY WATERPROOF MATERIAL. ANY RUBBER
MATERIAL.
Work Hygienic Practices: HAND WASHING IS RECOMMENDED AFTER WORKING WITH THIS
PRODUCT.
Supplemental Safety and Health: FL PT: WILL DECOMPOSE BEFORE REACHING FL PT
UPON HEATING. AUTOIGNIT TEMP: WILL DECOMPOSE BEFORE REACHING AUTOIGNIT UPON
HEATING. FIRST AID PROC: INDICATIONS OF ALLERGIC RXNS OR HYPERSENS. OVEREXP
CAN BE HAZ. GET MED ATTN. NOTE TO ATTENDING MD: NO KNOWN SPECIFIC ANTIDOTE.
GASTRIC LAVAGE MAY BE EFTIVE IF (OTHER INFO)
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Physical/Chemical Properties
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B.P. Text: DECOMPOSES BEFORE BOILING
Melt/Freeze Pt: =100.C, 212.F
Vapor Pres: NO SPECIFIC INFO FOUND
Spec Gravity: NO SPECIFIC INFO FOUND
Evaporation Rate & Reference: NO SPECIFIC INFO FOUND
Solubility in Water: HIGH
Appearance and Odor: WHITE FREE-FLOWING CRYSTALS OR GRANULES; SLIGHT PUNGENT
ODOR.
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Reactivity Data
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Stability Indicator: YES
Stability Condition To Avoid: HEAT, OPEN FLAME, SPARK. STABLE UNDER ORDINARY
CONDITIONS OF USE AND STORAGE.
Materials To Avoid: STRONG OXIDIZERS. CAUSTICS.
Hazardous Decomposition Products: SPONTANEOUS DECOMPOSITION: NOT EXPECTED TO
OCCUR. THERMAL DECOMPOSITION: HYDROGEN CHLORIDE. AMMONIA. CARBON AND NITROGEN
OXIDES. THE QUANTITY GENERATED MAY POSE A MINOR HAZARD.
Hazardous Polymerization Indicator: NO
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Toxicological Information
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Toxicological Information: ACUTE EXPOS: EYES/ORAL/SENSIT: NO RELEVANT HUMAN
EFTS DATA AVAIL. DERMAL/INHAL: HUMAN DATA FROM OCCUP EXPOS EXPERIENCE.
CHRONIC EFTS: SYSTEMIC EFTS: HUMAN DATA FROM OCCUP EXPOS EXPERIENCE. TARGET
ORGA NS: SKIN, RESP SYS, LIVER & KIDNEYS. MUTAGENICITY: CAUSES GENETIC
CHANGES (MUTAGENIC) IN SOME NON-MAMMALIAN ANIMALS. REPRO HAZS: NOT EXPECTED
TO OCCUR. CARCIN: CAUSES CANCER IN SOME LAB ANIMALS. NTP/I ARC/
OSHA: NOT LISTED. TOX INVESTIGATIONS: MICE: TDLO ORAL MOUSE: 260G/KG/78
WKS-CONTINUOUS; TUMORI-GENIC-CARCIN BY RTECS CRITERIA; LIVER-TUMORS OPD. LD50
INTRAPERITONEAL MOUSE: 200MG/KG; LD50 INTRAPER ITONEAL MOUSE:(STATE REG INFO)
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Ecological Information
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Ecological: NO TOX EFTS EXPECTED UPON ENVIRONMENTAL RELS. SHORT-TERM MOVEMENT
COULD BE RAPID DUE TO HIGH WATER SOL. MOVEMENT EXPECTED TO BE LIMITED BY
RELATIVELY RAPID ENVIRONMENTAL DETOXIFICATION. EXPECTED TO PA RTITION
STRONGLY INTO AQ ENVIRONMENTAL COMPONENTS. EXPECTED TO RAPIDLY DECOMPOSE IN
ENVIRONMENT. INVESTIGATIONS: LC50 FATHEAD MINNOWS, 96 HR: 44MG/L; OPD LC50
RAINBOW TROUT, 96 HR: 42.9MG/L; OPD EC50 DAPHNIA MAGNA, 48 HR: 1.4MG/L; OPD
BIODEGRADATION: ADAPTED A.S. AT 20C-PROD IS SOLD CARBON SOURCE: 33% COD
REMOVAL AFTER 120 HR; OPD WASTE WATER TREATMENT: DECOMP BY A SOIL
MICRO-FIORA: IN >64 DAYS; O PD.
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MSDS Transport Information
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Transport Information: NORTH AMERICAN EMER RESPONSE GUIDEBOOK: NONE ASSIGNED.
ICAO/IATA. DOT: SHIPPING DESIGNATION: DOES NOT MEET DEFINITION OF "HAZ MATL"
FOR TRANSPORT PURPOSES (US DOT). (PHENYLENEDIAMINES). HAZ CLASS, UN# ,
PACKING GROUP, REQD LABEL DESCRIPTION: NONE ASSIGNED. --OTHER INFO: WHERE
POTNTL FOR AIRBORNE PWDRS/DUSTS EXISTS. FOLLOWING CLTHG &/OR EQUIP MATLS
SHOULD BE PROTECTIVE: ANY WATERPROOF MATL. ANY RUB MATL. NO RESP PROT NEEDED
FOR MOST OPERATIONS; IF NEEDED, DISP-TYPE HALF-FACE MASK SHOULD BE EFTIVE.
NIOSH APPRVD FULL-FACE AIR-PURIFYING RESP IF NEEDED FOR LOW- TO MOD EXPOS.
(SEE SECTION 8 FOR RECOM S ON PROT MATLS OF CONSTRUCTION.)
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Regulatory Information
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Federal Regulatory Information: CONFORMS TO DEFINITION AS "HAZ CHEM" UNDER OSHA
HAZCOM REG (29 CFR PART 1910.1200(C) & APPENDIX B). INCLUDED ON EPA TOX
SUBSTANCES CTL ACT (TSCA). CERCLA RQ:SECTION 302/304/313: NOT LISTED.
CANADIAN R EGS: W CLASS D2A; D2B. EUROPEAN UNION: GERMANY/EINICS: NONE
ASSIGNED. RISK PHRASE: WARNING! R 45 MAY CAUSE CANCER. R 23/24/25 TOX BY
INHAL, IN CNTCT W/SKIN & IF SWALLOWED. SFTY PHRASE: S 53 AVOID
EXPOS-OBTAIN INSTRUCTINS BEFORE USE. S 28 AFTER CNTCT W/SKIN, WASH IMMED
W/PLENTY OF DETERGENT & WAT ER. S 36: WEAR SUITABLE PROT CLTHG. S 45: IN
CASE OF ACCIDENT/YOU FEEL UNWELL, SEEK MED ADVICE (SHOW LABEL IF POSS). SFTY
SYMBOL: TOX.
State Regulatory Information: CALIFORNIA PROP 65: THIS PROD IS OR CONTAINS
CHEM(S) KNOWN TO STATE OF CALIFORNIA TO CAUSE CANCER. --TOXICOLOGICAL INFO:
200MG/KG; DETAILS OF TOX EFTS NOT REPORTED OTHER THAN LETHAL DOSE VALUE; OPD.
T D ORAL MOUSE: 518G/KG/78 WKS-CONTINUOUS; TUMORI-GENIC-CARCIN BY RTECS
CRITERIA; LIVER-TUMORS OPD. RATS: TDLO ORAL RAT: 130G/KG/78 WKS-CONTINUOUS;
TUMORI-GENIC-EQUIVOCAL TUMORIGENIC AGENT BY RTECS CRIT ERIA; LIVER-TUMORS;
OPD. LD50 INTRAPERITONEAL RAT: 290MG/KG; DETAILS OF TOX EFTS NOT REPORTED
TOERH THAN LETHAL DOSE VALUE; OPD. LDLO SUBCUTANEOUS RAT: 600MG/KG; DETAILS
OF TOX EFTS NOT REPORTED OTHER THAN LETHAL DOSE VALUE; OPD.
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Other Information
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Other Information: NFPA 704M RATING: FIRE 1; HLTH 2; REACTIVE 1; SPECIAL NONE.
RATINGS NOT REVIEWED BY NFPA. CHEM FORMULA: C6 H8 N2 H2 C12. MW: 181.08.
SUPDAT: INDICATED FOR INGEST. ACTIVATED CARBON MAY PROVIDE DETOXIFI CATION
ACTIVITY. BE ALERT TO EARLY INDICATIONS OF ALLERGIC RXNS OR HYPERSENS. TREAT
SYMP. MAY CAUSE CHGS IN RSLTS OF COMMON CLINICAL URINE TESTS. EFTS TYPICALLY
RESOLVE COMPLETELY UPON REMOVAL FROM SO URCE OF EXPOS W/OUT TREATMENT. SPILL
PROC:CAN BE EFTIVE IN CLEANING UP SPILLS. DEPOSIT IN APPROP CNTNRS FOR
REMOVAL & DISP. LAUNDER CLTHG BEFORE REUSE. PPE FOR SPILL CNDTNS: GLOVES
IF CNTCT POSS. CHEM GOGGS TO REDUCE CNTCT(TRANSPORT INFO)
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HAZCOM Label
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MSDS NAME: OPD (O-PHENYLENEDIAMINE DIHYDROCHLORIDE), 15974
Company: LIFE TECHNOLOGIES INC
PO Box: 68
City: GRAND ISLAND NY
Zipcode: 14072
Health Emergency Phone: 301-431-8585
Label Required IND: Y
Date Of Label Review: 11/11/1999
Status Code: A
Origination Code: F
Eye Protection IND: YES
Skin Protection IND: YES
Signal Word: WARNING
Respiratory Protection IND: YES
Health Hazard: Moderate
Contact Hazard: Moderate
Fire Hazard: Moderate
Reactivity Hazard: None
Hazard And Precautions: COMBUSTIBLE. DUST MAY BE FLAMMABLE. ACUTE: EYE
EXPOSURE: MAY CAUSE PAIN, IRRITATION, CONJUNCTIVITIS. SKIN OVEREXPOSURE:
CONTACT WITH SOLID MAY IRRITATE/INFLAME. MAY CAUSE REDNESS (ERYTHEMATOUS).
INHA LATION: MAY CAUSE NASAL & RESPIRATORY TRACT IRRITATION, COUGHING,
CHEST PAIN, BREATHING DIFFICULTY, WHEEZING OR SHORTNESS/BLOCKAGE OF BREATH
(DYSPNEA). INGESTION: MAY BE HARMFUL IF SWALLOWED. MAY CAU SE NAUSEA AND/OR
VOMITING. MAY BE ABSORBED IN THE GASTROINTESTINAL TRACT IN TOXIC QUANTITIES.
CHRONIC: NONE LISTED BY MANUFACTURER.
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