amphotericin b non-hazardous ients (na 0004) sodium deoxycholate water
LIFE TECHNOLOGIES, INC -- 15290,FUNGIZONE ANTIMYCOTIC,LIQUID
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Material Safety Data Sheet
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NIIN: 01-084-9453
MSDS Num: CKNWG
MSDS NAME: 15290,FUNGIZONE ANTIMYCOTIC,LIQUID
Responsible Party
Name: LIFE TECHNOLOGIES, INC
Box: 68
City: GRAND ISLAND NY 14072
Info Phone: 800-828-6686
Emergency Phone Number: 301-431-8585
Resp. Party Other MSDS No.: MSDS NO: 15290, CATALOG NO: 15290
Preparer's Name: NOT PROVIDED
Review Ind: Y
Published: Y
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Contractor Summary
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Name: CAL-TEK CHEM-LUBE CORP
Address: 17160 COLUMBIA DR
Box: 2559
City: CASTRO VALLEY CA 94546-0559
Phone: 800-476-0678
Name: LIFE TECHNOLOGIES, INC
Box: 68
City: GRAND ISLAND NY 14072
Phone: 800-828-6686
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Item Description Information
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Item Name: AMPHOTERICIN B FOR INJECTION,USP
Unit of Issue: BT
UI Container Qty: 1
Type of Container: BOTTLE
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Ingredients
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Cas: 1397-89-3
RTECS #: BU2625000
Name: AMPHOTERICIN B
Percent by Wt: .03
Other REC Limits: NOT PROVIDED
OSHA PEL: NOT ESTABLISHED
ACGIH TLV: NOT ESTABLISHED
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Name: NON-HAZARDOUS INGREDIENTS (NA 0004)
Percent by Wt: .95
Other REC Limits: NOT PROVIDED
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Cas: 302-95-4
RTECS #: FZ2250000
Name: SODIUM DEOXYCHOLATE
Percent by Wt: .02
Other REC Limits: NOT PROVIDED
OSHA PEL: NOT ESTABLISHED
ACGIH TLV: NOT ESTABLISHED
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Cas: 7732-18-5
RTECS #: ZC0110000
Name: WATER
Percent by Wt: 99.
Other REC Limits: NOT PROVIDED
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Health Hazards Data
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LD50 LC50 Mixture: NOT PROVIDED
Route Of Entry Inds - Inhalation: YES
Skin: NO
Ingestion: YES
Carcinogenicity Inds - NTP: NO
IARC: NO
OSHA: NO
Effects of Exposure: EFFECTS OF OVEREXPOSURE: ACUTE: FROM EYE EXPOSURE:
SURFACE-CONTACT EFFECTS ONLY ARE EXPECTED. MAY CAUSE IRRITATION OR REDDENING.
NOT EXPECTED TO BE SIGNIFICANTLY ABSORBED. FROM SKIN OVEREXPOSURE: SURF
ACE-CONTACT EFFECTS ONLY ARE EXPECTED. CONTACT WITH LIQUID MAY
IRRITATE/INFLAME THE SKIN. CONTACT WITH LIQUID MAY CAUSE A BURNING SENSATION
IN THE SKIN. NOT EXPECTED TO BE SIGNIFICANTLY ABSORBED. FROM INHALATION: NO
TOXICITY EXPECTED. MAY CAUSE NASAL IRRITATION. FROM INGESTION: NO TOXICITY
EXPECTED. MAY CAUSE ALLERGIC GASTROINTESTINAL TRACT EFFECTS.
Explanation Of Carcinogenicity: DOES NOT CAUSE CANCER (CARCINOGENIC) IN EXPOSED
HUMANS. NTP: NOT LISTED. IARC: NOT LISTED.
OSHA: NOT LISTED.
Signs And Symptions Of Overexposure: FROM EYE EXPOSURE: SURFACE-CONTACT EFFECTS
ONLY ARE EXPECTED. MAY CAUSE IRRITATION OR REDDENING. NOT EXPECTED TO BE
SIGNIFICANTLY ABSORBED. FROM SKIN OVEREXPOSURE: SURFACE-CONTACT EFFECTS ONLY
ARE EXP ECTED. CONTACT WITH LIQUID MAY IRRITATE/INFLAME THE SKIN. CONTACT
WITH LIQUID MAY CAUSE A BURNING SENSATION IN THE SKIN. NOT EXPECTED TO BE
SIGNIFICANTLY ABSORBED. FROM INHALATION: NO TOXICITY EXPECTE D. MAY CAUSE
NASAL IRRITATION. FROM INGESTION: NO TOXICITY EXPECTED. MAY CAUSE ALLERGIC
GASTROINTESTINAL TRACT EFFECTS.
Medical Cond Aggravated By Exposure: RENAL INSUFFICIENCY. ALLERGY OR
HYPERSENSITIVITY TO: ANTIBIOTICS, AMINOGLYCOSIDE ANTIBOTICS (E.G. KANAMYCIN,
STREPTOMYCIN).
First Aid: EYE: WASH EYES AND SKIN WITH WATER. SKIN: WASH EYES AND SKIN WITH
WATER. MOST EXPOSURES DO NOT REQUIRE MEDICAL ATTENTION. BE ALERT TO EARLY
INDICATIONS OF ALLERGIC REACTIONS OR HYPERSENSITIVITY. INHAL ATION: MOST
EXPOSURES DO NOT REQUIRE MEDICAL ATTENTION. BE ALERT TO EARLY INDICATIONS OF
ALLERGIC REACTIONS OR HYPERSENSITIVITY. INGESTION: MOST EXPOSURES DO NOT
REQUIRE MEDICAL ATTENTION. BE ALERT TO EARLY INDICATIONS OF ALLERGIC
REACTIONS OR HYPERSENSITIVITY.
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Handling and Disposal
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Spill Release Procedures: RELEASES MAY BE SUBJECT TO REPORTING. CHECK AND
COMPLY WITH APPLICABLE LAWS AND REGULATIONS. WATERPROOF CLOTHING AND GLOVES
SHOULD BE USED. ABSORB SPILL USING THE FOLLOWING MATERIAL(S): MOST ABSORBENT
MATERIALS SHOULD BE EFFECTIVE. FLUSH AREA WITH WATER. DEPOSIT IN APPROPRIATE
CONTAINERS FOR REMOVAL AND DISPOSAL. SPECIAL INSTRUCTIONS: THE QUANTITY
GENERATED IS LIKELY TO BE HAZARDOUS.
Neutralizing Agent: NOT RELEVANT
Waste Disposal Methods: THIS PRODUCT IS NOT RECYCLABLE OR REUSABLE. MAY BE
INCINERATED IN A HAZARDOUS WASTE INCINERATOR. PRODUCT SHOULD BE REMOVED TO A
HAZARDOUS WASTE LANDFILL ONLY IF NO OTHER DISPOSAL METHOD IS AVAILABLE. NOTE
THAT TREATMENT OR DISPOSAL ACTIVITIES MAY BE SUBJECT TO LAWS AND REGULATIONS.
IT IS THE PURCHAS ER'S RESPONSIBILITY TO COMPLY.
Handling And Storage Precautions: NO SPECIAL MEASURES NEEDED FOR NORMAL
OPERATIONS. STORE IN A DARK AREA. KEEP AWAY FROM LIGHT. KEEP AWAY FROM HEAT.
STORAGE TEMP: DEEP FROZEN (<-15). STORAGE PRESSURE: ATMOSPHERIC. SEE
EXPIRATION DATE FOR STABILITY UNDER PROPER STORAGE CONDITIONS.
Other Precautions: NOT PROVIDED
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Fire and Explosion Hazard Information
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Flash Point: >140.C, 284.F
Flash Point Text: DECOMPOSES
Autoignition Temp Text: DECOMP
Lower Limits: NOT APPLICAB
Upper Limits: NONE PROVIDE
Extinguishing Media: USE MEANS APPROPRIATE FOR SURROUNDING MATERIALS.
Fire Fighting Procedures: USE PROTECTIVE EQUIPMENT APPROPRIATE FOR SURROUNDING
MATERIALS.
Unusual Fire/Explosion Hazard: NOT PROVIDED
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Control Measures
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Respiratory Protection: AIR PURIFYING RESPIRATOR CANISTERS/CARTRIDGES: NO
SPECIFIC REQUIREMENTS.
Ventilation: AREA VENTILATION IS GENERALLY ADEQUATE. LOCAL EXHAUST PROPERLY
USED AT THE SOURCE OF AIRBORNE GENERATION GENERALLY PROVIDES THE BEST
CONTROL.
Protective Gloves: ANY WATERPROOF MATERIAL.
Eye Protection: SAFETY GLASSES
Other Protective Equipment: NOT PROVIDED
Work Hygienic Practices: HAND WASHING IS RECOMMENDED AFTER WORKING WITH THIS
PRODUCT. CLOTHING SHOULD BE LAUNDERED BEFORE REUSE.
Supplemental Safety and Health: NONE
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Physical/Chemical Properties
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HCC: V5
NRC/State LIC No: NOT RELEVANT
Boiling Point: =100.C, 212.F
Melt/Freeze Pt: =0.C, 32.F
Decomp Text: NOT PROVIDED
Vapor Pres: 23.75 @ 25 DEG C (MM HG)
Vapor Density: 0.62(AIR=1
Spec Gravity: 0.997 @ 25 DEG C
PH: 4-7
Viscosity: 0.89 @ 25 DEG C (CP)
Evaporation Rate & Reference: 1
Solubility in Water: AN AQUEOUS SOLUTION
Appearance and Odor: CLEAR LIGHT-YELLOW LIQUID, NO ODOR
Corrosion Rate: NOT PROVIDED
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Reactivity Data
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Stability Indicator: YES
Stability Condition To Avoid: SEE EXPIRATION DATE FOR STABILITY UNDER PROPER
STORAGE CONDITIONS. KEEP AWAY FROM LIGHT. KEEP AWAY FROM HEAT.
Materials To Avoid: NO KNOW CHEMICAL INCOMPATIBILITIES.
Hazardous Decomposition Products: IN THE QUANTITY SOLD OR USED, THIS PRODUCT
SHOULD POSE LITTLE OR NO HAZARD. CARBON AND NITROGEN OXIDES. SODIUM OXIDE
(NA2 O). SULFUR OXIDES.
Hazardous Polymerization Indicator: NO
Conditions To Avoid Polymerization: NONE
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Toxicological Information
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Toxicological Information: RATS: LD50 11300 UG/KG INTRAVENOUS RAT, AMPHOTERICIN
B 10 MMOL/KG, SODIUM DEOXYCHOLATE TDL0 1400 MG/KG INTRAPERITONEAL RAT;
REPRODUCTIVE EFFECTS, SODIUM DEOXYCHOLATE TDL0 1400 MG/KG INTRAPERITONEAL RA
T; LD50 1370 MG/KG ORAL RAT.
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Ecological Information
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Ecological: NO TOXICITY EXPECTED.
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MSDS Transport Information
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Regulatory Information
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Sara Title III Information: SARA: NOT LISTED.
Federal Regulatory Information: OSHA: NOT A "HAZARDOUS CHEMICAL" UNDER US OSHA
HAZCOM REGULATIONS (29 CFR PART 1910.1200). TSCA: ALL CONSTITUENTS OF THIS
PRODUCT: INCLUDED ON THE US EPA TOXIC SUBSTANCE CONTROL ACT (TSCA; 40 CFR
PART 710) INVENTORY AS A NATURAL PRODUCT. SOME CONSTITUENTS OF THIS PRODUCT:
REGULATED BY THE FOOD AND DRUG ADMINISTRATION (FDA).
State Regulatory Information: NOT PROVIDED
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Other Information
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Other Information: NONE
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Transportation Information
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Trans ID NO: 153576
MSDS NAME: 15290,FUNGIZONE ANTIMYCOTIC,LIQUID
MSDS Prepared Date: 04/26/1999
Review Date: 06/14/2000
Multiple KIT Number: 0
Unit Of Issue: BT
Container QTY: 1
Type Of Container: BOTTLE
Additional Data: NOT REGULATED FOR TRANSPORTATION, PER MSDS.
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Detail DOT Information
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DOT PSN Code: ZZZ
DOT Proper Shipping Name: NOT REGULATED BY THIS MODE OF TRANSPORTATION
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Detail IMO Information
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IMO PSN Code: ZZZ
IMO Proper Shipping Name: NOT REGULATED FOR THIS MODE OF TRANSPORTATION
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Detail IATA Information
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IATA PSN Code: ZZZ
IATA Proper Shipping Name: NOT REGULATED BY THIS MODE OF TRANSPORTATION
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Detail AFI Information
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AFI PSN Code: ZZZ
AFI Proper Shipping Name: NOT REGULATED BY THIS MODE OF TRANSPORTATION
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HAZCOM Label
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MSDS NAME: 15290,FUNGIZONE ANTIMYCOTIC,LIQUID
Assigned IND: Y
Company: LIFE TECHNOLOGIES, INC
PO Box: 68
City: GRAND ISLAND NY
Zipcode: 14072
Health Emergency Phone: 301-431-8585
Label Required IND: Y
Date Of Label Review: 06/14/2000
Status Code: A
MFG Label NO: NOT PROVIDED
Origination Code: F
Eye Protection IND: YES
Skin Protection IND: YES
Signal Word: CAUTION
Respiratory Protection IND: NO
Health Hazard: Slight
Contact Hazard: Slight
Fire Hazard: Slight
Reactivity Hazard: None
Hazard And Precautions: TARGET ORGANS: NONE PROVIDED. FIRST AID: EYE: WASH EYES
AND SKIN WITH WATER. SKIN: WASH EYES AND SKIN WITH WATER. MOST EXPOSURES DO
NOT REQUIRE MEDICAL ATTENTION. BE ALERT TO EARLY INDICATIONS OF ALLE RGIC
REACTIONS OR HYPERSENSITIVITY. INHALATION: MOST EXPOSURES DO NOT REQUIRE
MEDICAL ATTENTION. BE ALERT TO EARLY INDICATIONS OF ALLERGIC REACTIONS OR
HYPERSENSITIVITY. INGESTION: MOST EXPOSURES DO N OT REQUIRE MEDICAL
ATTENTION. BE ALERT TO EARLY INDICATIONS OF ALLERGIC REACTIONS OR
HYPERSENSITIVITY.
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Disclaimer (provided with this information by the compiling agencies): This
information is formulated for use by elements of the Department of Defense.
The United States of America in no manner whatsoever expressly or implied
warrants, states, or intends said information to have any application, use or
viability by or to any person or persons outside the Department of Defense
nor any person or persons contracting with any instrumentality of the United
States of America and disclaims all liability for such use. Any person
utilizing this instruction who is not a military or civilian employee of the
United States of America should seek competent professional advice to verify
and assume responsibility for the suitability of this information to their
particular situation regardless of similarity to a corresponding Department
of Defense or other government situation.