LD50 LC50 Mixture:ORAL LD50 (RAT): >8000 MG/KG (SEE SUPP)
Routes of Entry: Inhalation:YES Skin:NO Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:CALCIUM LEUCOVORIN-LOW ORDER OF
TOXICITY. ALLERGIC REACTIONS HAVE BEEN REPORTED FOLLOWING
ORAL/INTRAVENOUS ADMINISTRATION.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:CALCIUM LEUCOVORIN-LOW ORDER OF TOXICITY.
ALLERGIC REACTIONS HAVE BEEN REPORTED FOLLOWING ORAL/INTRAVENOUS
ADMINISTRATION.
======================= First Aid Measures =======================
Eyes: IMMEDIATELY FLUSH W/PLENTY OF COOL, LOW-PRESSURE WATER
FOR 20 MINS. SKIN: PROMPTLY WASH W/SOAP & COOL RUNNING WATER.
INHALATION: REMOVE TO FRESH AIR. GIVE CPR/OXYGEN IF NEEDED.
INGESTION: DON'T INDUCE VOMITING EXCEPT AS DIRECTED BY MEDICAL
PERSONNEL. DON'T INDUCE VOMITING/GIVE ANYTHING BY MOUTH IF
UNCONSCIOUS. OBTAIN MEDICAL ATTENTION IN ALL CASES.
Respiratory Protection:WEAR AN APPROVED AIR-PURIFYING RESPIRATOR
W/HIGH-EFFICIENCY CARTRIDGES ADEQUATE TO CONTROL EXPOSURE IF PEL IS
EXCEEDED.
Ventilation:CLOSED-SYSTEM HANDLING, LABORATORY BENCH HOOD/LOCAL EXHAUST
TO CONTROL DUST/MIST.
Protective Gloves:RUBBER
Eye Protection:RECOMMENDED
Work Hygienic Practices:WASH HANDS & FACE AFTER HANDLING.
REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE REUSE.
Supplemental Safety and Health
ORAL LD50 INFORMATION IS FOR CALCIUM LEUCOVORIN.
Waste Disposal Methods:DISPOSE OF IAW/FEDERAL, STATE & LOCAL
REGULATIONS. INCINERATION IS RECOMMENDED.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.