MSDS for 2,4,6-Collidine,                                                                      Page 1 of 7

Ref. no: 0010B00 Div 05 msds 2,4,6-Collidine                                     Jubilant Organosys Limited

Date of Issue: 08 July 2005

Revision: 00

                          MATERIAL SAFETY DATA SHEET



1.               CHEMICAL PRODUCT & MANUFACTURER’S DETAILS



PRODUCT NAME : 2,4,6-Collidine

MANUFACTURER

FACTORY & REGISTERED OFFICE:                            HEAD OFFICE:

Jubilant Organosys Limited,                             Jubilant Organosys Limited

Bhartiagram, Gajraula                                   Plot 1-A, Sector 16-A,

District: Jyotiba Phuley Nagar                          Institutional Area, Noida,

Uttar Pradesh-244223 , India                            Uttar Pradesh-201301 India.

PHONE NO: +91-5924-252353 unto 252360                   PHONE NO: +91-120-2516601

Contact Department-Safety: Extension 298                Contact department: EHS

FAX NO : 91-5924-252352                                 FAX NO : +91-120-2516629

EMERGENCY PHONE: +91-5924-268141                        Email: support@jubl.com







2.                                CHEMICAL IDENTIFICATION

�    CHEMICAL NAME                             : 2,4,6-Collidine

�    SYNONYMS                                  : 2,4,6-Trimethylpyridine, s-Collidine

�    SYSTEMATIC NAME                           : Pyridine, 2,4,6-trimethyl- (9CI+)

�    OTHER LANGUAGE NAMES

                                                  De : 2,4,6-Trimethylpyridin

                                                  Es : 2,4,6-trimetilpiridina

                                                  Fr : 2,4,6-triméthylpyridine

                                                  Czech 2,4,6- Kollidin

�    CHEMICAL CLASSIFICATION                   : Alkylpyridine

�    CHEMICAL FORMULA                          : C8H11N

�    C.A.S. NO                                 : 108-75-8

�    EINECS                                    : 203 - 613 �3



3.              HAZARD IDENTIFICATION & HEALTH HAZARD

�    Flammable liquid and vapour

�    Corrosive. Causes burns. Alkaline. Causes skin burns. May cause burns to the respiratory and

     gastrointestinal tract on inhalation or respiration.

�    Harmful if swallowed

�    Route of entry: inhalation, skin, ingestion

�    Irritating to eyes, skin and respiratory system

�    Effects and symptoms

     � Eyes: Corrosive. Causes eye damage.

     � Skin: Corrosive. Causes skin burns

     � Inhalation: Corrosive. Causes respiratory tract burns

     � Ingestion: Causes irritation and may result in burns to the mouth, throat and esophagus.

MSDS for 2,4,6-Collidine,                                                                       Page 2 of 7

Ref. no: 0010B00 Div 05 msds 2,4,6-Collidine                                      Jubilant Organosys Limited

Date of Issue: 08 July 2005

Revision: 00







                                     FIRST AID MEASURES

4.

Persons who have been in contact with the substance or have inhaled fumes should get immediate

medical attention. Pass on all available product information.

Eye:

Immediately flush eyes with plenty of water for at least 15 minutes by separating eyelids with fingers.

Get medical help.

Skin:

Remove contaminated clothing and shoes. Persons who have been in contact with the substance or

have inhaled fumes should get immediate medical attention. Pass on all available product

information. Wash contaminated clothing before reuse.

Inhalation:

Remove the affected person(s) to fresh air. If not breathing, give artificial respiration. If breathing is

difficult, give oxygen. Do not use mouth to mouth respiration

Ingestion:

 Wash out mouth with water if person is conscious. Make the affected person drink plenty of water.

Call a physician.



5.                                FIRE FIGHTING MEASURES

Flash point: 57 C (134.6 F) Liquid mp �430C, bp 171 deg C

                 0          0



Extinguishing media:

Dry chemical powder, chemical foam, and alcohol resistant foam. Do not use water jet or fog (spray)

to extinguish. Water can be effective in cooling down the fire-exposed containers. Use water spray to

knock down fire fumes if possible..

Special fire fighting procedure:

Wear full protective clothing, wear self contained breathing apparatus (SCBA) in fire situations.

Avoid unnecessary run-off of extinguishing media, which may cause pollution.

Unusual fire and explosion hazard:

When heated to decomposition it emits toxic vapors of nitrogen oxides, carbon monoxide and carbon

dioxide.



6.                        ACCIDENTAL RELEASE MEASURES

�    Eliminate ignition sources.

�    Keep upwind. Put on protective equipment before entering danger area.

�    Minimise number of personnel in risk area.

�    Stop leaks if possible.

�    Contain spillage by any means available.



�    Use low sparking hand tools and intrinsically safe equipment.

�    Recover spilled product in vented container fitted with absorption filter if possible.

�    Absorb liquid in sand or earth or any other suitable material, or cover with foam.

�    If substance has entered a water course or sewer, inform the responsible authority.

�    Ventilate sewers and basements where there is no risk to personnel or public.

MSDS for 2,4,6-Collidine,                                                                    Page 3 of 7

Ref. no: 0010B00 Div 05 msds 2,4,6-Collidine                                   Jubilant Organosys Limited

Date of Issue: 08 July 2005

Revision: 00









7.                                HANDLING AND STORAGE

�    Store in cool dry and ventilated place away from heat, flame and sparks and incompatible

     substances

�    Keep containers closed

�    Wear suitable protective clothing, gloves and eye/face protection & use non-sparking tools.



8.          EXPOSURE CONTROLS/PERSONAL PROTECTION

�    Exposure Controls: Use explosion proof local or general mechanical ventilation. Facilities using

     this chemical will need emergency showers and eye-wash facilities.

�    Personal Protection

     � General: Avoid inhalation and skin contact. Wash thoroughly after handling

     � Eyes: Use goggles and/or face-shield

     � Clothes: Standard laboratory or work clothing.

     � Gloves: Required

     � Respiratory Apparatus: Use an approved respirator if conditions demand. Experienced

         personnel to wear positive pressure self-contained breathing apparatus (SCBA) when fighting

         fires involving this material.

�    Exposure limits:

     � No exposure limits from ACGIH, NIOSH or any other organisation is known to be available.

MSDS for 2,4,6-Collidine,                                                             Page 4 of 7

Ref. no: 0010B00 Div 05 msds 2,4,6-Collidine                            Jubilant Organosys Limited

Date of Issue: 08 July 2005

Revision: 00





9. PHYSICOCHEMICAL PROPERTIES & FIRE/ EXPLOSION HAZARD DATA

        PHYSICAL STATE                         : Liquid

        ODOUR                                  : Aromatic

                                               : 171 °C

        BOILING POINT

        MELTING POINT                          : -43°C

        FLASH POINT                            : 57°C

        pKa                                     : 7.43 @25°C

        log Kow                                : 1.88

        Koc                                    : 250

                                               : 8.8X10-6 atm-m3/mole

        HENRY CONSTANT

        VAPOUR PRESSURE                        : 2mm Hg @25°C

        SPECIFIC GRAVITY (WATER=1)             : 0.92

        VAPOR DENSITY (AIR=1)                  : Data not available

        SOLUBILITY IN WATER g/100 ml           : 20.8 g @ 6 deg C,

                                                   3.5 g @ 20 deg C,

                                                   1.8 g @ 100 deg C

        pH                                     : Data not available

                                               : Data not available

        FLAMMABILITY



        LEL                                    :   Data not available

        UEL                                    :   Data not available

        AUTO IGNITION TEMPERATURE              :   Data not available

        EXPLOSIVE SENSITIVITY TO IMPACT        :   Data not available

        EXPLOSIVE SENSITIVITY TO-

        STATIC ELECTRICITY                     : Data not available

        FLAMMABLE MATERIAL                     : Yes

        PYROPHORIC MATERIAL                    : No

        EXPLOSIVE MATERIAL                     : No

        OXIDIZER                               : No

        ORGANIC PEROXIDE                       : No

        CORROSIVE MATERIAL                     : No

        MOLECULAR WEIGHT                       : 121.18

MSDS for 2,4,6-Collidine,                                                                      Page 5 of 7

Ref. no: 0010B00 Div 05 msds 2,4,6-Collidine                                     Jubilant Organosys Limited

Date of Issue: 08 July 2005

Revision: 00









10.                              STABILITY AND REACTIVITY

�     Stable under normal temperature and pressures

�     Incompatible with

           Strong oxidising agents

�     Hazardous combustion or decomposition products:

      thermal decomposition may produce carbon monoxide, carbon dioxides, oxides of nitrogen,

      irritating & toxic fumes.

�     Conditions to avoid: High temperature, mechanical shock, incompatible materials, ignition

      sources, excess heat.

�     NFPA rating: Health: 2, Flammability: 2, Reactivity:0 (estimated)



11.                      TOXICOLOGICAL INFORMATION

�     Acute effects:

      � Corrosive action on skin.

      � Harmful if swallowed.

      � May be corrosive/irritative on inhalation or ingestion to the respiratory and gastrointestinal

          tract.

      � Collidines cause symptoms resembling those of pyridine which are largely non specific and

          include cramps, ataxia, diarrhoea and unconsciousness. Delayed death following single doses

          are unlikely. Survivors gain weight normally. (Clayton, G. D.and F. E. Clayton (eds.). Patty’s

          Industrial Hygiene and Toxicology:. Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York:

          John Wiley Sons, 1981-1982., p. 2724)

      � Mode of entry: Includes inhalation and skin entry.

�     Chronic effects:. The full toxicological profile of this chemical is not available. Based on

      chemical class the following general observations may be considered. Overexposure may cause

      delayed kidney injury. Chronic ingestion may cause liver damage. Prolonged or repeated eye

      contact may cause conjunctivitis. Chronic ingestion may cause neurological symptoms.

�     Toxicity:

      � RTECS: UU0970000 Entry/Update Date (DATE): Oct 1997

      ORL RAT LD50               : 400 mg/kg          85JCAE �,847,1986

      SKN GPG LD50               : 1000 mg/kg         85JCAE �,847,1986

�     Carcinogenicity, Mutagenicity and Reproductive Toxicity

      � Not listed as carcinogenic by IARC, NTP or ACGIH.

      � Not listed in EU consolidated CMR list. Not derived from coal tar bases,

      � Mutagenicity, Reproductive toxicity: No data available.





12.                      ECOLOGICAL INFORMATION

�     Data not available

�     Do not permit this material to enter environmental bodies.

MSDS for 2,4,6-Collidine,                                                                      Page 6 of 7

Ref. no: 0010B00 Div 05 msds 2,4,6-Collidine                                     Jubilant Organosys Limited

Date of Issue: 08 July 2005

Revision: 00



13.                      DISPOSAL CONSIDERATION

�     Burn in a chemical incinerator equipped with an afterburner and scrubber

�     Observe all federal, state and local environmental regulations



14.                              TRANSPORT INFORMATION

Classification by IMO/IMDG/ICAO/IATA

PROPER SHIPPING NAME : FLAMMABLE LIQUID, TOXIC, .N.O.S. (2,4,6-Trimethylpyridine)

UN/ID NUMBER                   : 1992

UN HAZARD CLASS                : 3, Sub-risk 6.1

UN PACKING GROUP               : III



Classification by European Union

PROPER SHIPPING NAME :CORROSIVE LIQUID, FLAMMABLE, N.O.S.(2,4,6-Trimethylpyridine)

UN/ID NUMBER                            : 2920

UN HAZARD CLASS                         : 8, Sub-risk 3

UN PACKING GROUP                        : II



Classification under Canadian TDG

PROPER SHIPPING NAME :CORROSIVE LIQUID, FLAMMABLE, N.O.S.(2,4,6-Trimethylpyridine)

UN/ID NUMBER                            : 2920

UN HAZARD CLASS                         : 8, Sub-risk 3

UN PACKING GROUP                        : II



Classification by New Zealand

PROPER SHIPPING NAME : FLAMMABLE LIQUID,.N.O.S. (2,4,6-Trimethylpyridine)

UN/ID NUMBER                : 1993 (NZ Gztte 35, March 26, 2004.)

UN HAZARD CLASS             :3

PACKING GROUP               : III

HSNO Classification         : 3.1C, 6.1C, 6.3B, 6.9A, 9.1B, 9.3B (NZ Gztte 35, March 26, 2004.)



Classification by US DOT

PROPER SHIPPING NAME : FLAMMABLE LIQUID, TOXIC, .N.O.S. (2,4,6-Trimethylpyridine)

UN/ID NUMBER             : 1992

UN HAZARD CLASS          : 3, Sub-risk 6.1

UN PACKING GROUP         : III

MSDS for 2,4,6-Collidine,                                                                      Page 7 of 7

Ref. no: 0010B00 Div 05 msds 2,4,6-Collidine                                     Jubilant Organosys Limited

Date of Issue: 08 July 2005

Revision: 00



15.                              REGULATORY INFORMATION

European information

EC#203 - 613 �3

Pictogram: C, F, Xn, Xi Reduced labelling (Directive 1999/45/EC Article 10): C,F

� R 10 Flammable.

� R 22 Harmful if swallowed.

� R 35 Causes severe burns.

� R 36/37/38 Irritating to eyes, respiratory system and skin.

� S-26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice

� S-36/37/39 Wear suitable protective clothing, gloves, eye/face protection.

� S-45 In case of accident, if you feel unwell, seek medical advice immediately



US information

� Listed on the TSCA 8(b) inventory

� None of the chemicals in this product is listed under TSCA section 12b

� None of the chemicals in this product have an RQ under SARA Section 302 RQ

� None of the chemicals in this product have an TPQ under SARA Section 302 TPQ

� None of the chemicals in this product is reported under SARA Section 313

� None of the chemicals in this product contains any class1 & class2 ozone depletors , neither

   contain any hazardous air pollutants under ‘Clean Air Act�

� None of the chemicals in this product is listed as Hazardous substances or priority pollutants or

   Toxic substances list under ‘Clean Water Act�



Canada

Present on the DSL



16.                              OTHER INFORMATION

Information contained in this MSDS is believed to be correct but no representation, guarantee or

warranties of any kind are made as to its accuracy, suitability for a particular application or results to

be obtained from them. This MSDS shall be used as guide only. JUBILANT ORGANOSYS

LIMITED makes no warranties expressed or implied of the adequacy of this document for any

particular purpose.

Document Name:        0010B00 Div 05 msds 2,4,6-Collidine

Date: 08 July 2005

Revision Number:      00