MATERIAL SAFETY DATA SHEET
Methylene Blue
Page 1 of 3
Date of Issue: 21 Sept 06
STATEMENT OF HAZARDOUS NATURE
Hazardous according to criteria of Worksafe Australia
COMPANY DETAILS
ProSciTech
Company:
Address: PO Box 111, Thuringowa Central Qld. 4817 Australia
Street Address: 1/11 Carlton Street, Kirwan, Qld, 4817. Australia
Telephone Number: (07) 4773 9444
Fax Number: (07) 4773 2244
IDENTIFICATION SECTION
Methylene Blue
Product Name
Basic Blue, trihydrate, Methylene blue trihydrate; 3,7-
Other Names
Bis(dimethylamino) phenazathionium chloride trihydrate.
C124, C1241
Product Code
None allocated
U.N. Number
None allocated
Dangerous Goods Class
and Subsidiary Risk
None allocated
Hazchem Code
None allocated
Poison Schedule
General stain for animals, histology
Use
Physical Description and Properties
Odourless dark green crystals with a brown lustre
Appearance
MP 190oC
Boiling Point/Melting Point
No data
Vapour Pressure
No data
Specific Gravity
No data
Flash Point
Not determined
Flammability Limits
1g in 25ml water
Solubility in water
Other Properties
Ingredients
Chemical Name CAS Number Proportion
C16H18ClN3S.3H2O 7220-79-3 100%
Page 2 of 3
Methylene Blue
HEALTH HAZARD INFORMATION
Health Effects:
Acute
A burning sensation of the mouth may be noted following ingestion of methylene blue. May
Swallowed:
cause nausea, vomiting, diarrhea, and gastritis. Large doses may cause abdominal and chest
pain, headache, profuse sweating, mental confusion, painful micturation, and
methemoglobinemia.
No adverse effects expected. May cause mechanical irritation.
Eye:
Not expected to be a hazard from skin exposure. Methylene blue may colour the skin a bluish
Skin:
colour. May cause photosensitization.
No adverse health effects expected from inhalation. May cause a short period of rapid or
Inhaled:
difficult breathing.
No data
Chronic:
First Aid:
Induce vomiting immediately as directed by medical personnel. Never give anything by
Swallowed:
mouth to an unconscious person.
Immediately flush eyes with copious amounts of water for at least 15 minutes, lifting lower
Eye:
and upper eyelids occasionally. Get medical attention.
Immediately flush skin with plenty of soap and water for at least 15 minutes. Remove
Skin:
contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before
reuse. Get medical attention if irritation develops.
Remove to fresh air. Get medical attention for any breathing difficulty.
Inhaled:
Eye bath, safety shower
First Aid Facilities:
Treat symptomatically and supportively.
Advice to Doctor
PRECAUTIONS FOR USE
No exposure standard allocated
Exposure Standards:
Use adequate general or local exhaust ventilation to keep fume or dust levels as low as
Engineering
possible
Controls:
If airborne concentration is high, use an appropriate respirator or dust mask. For emergencies,
Personal Protection:
a self-contained breathing apparatus may be necessary. Wear protective gloves and clean
body-covering clothing. Use safety glasses with sideshields. Contact lenses should not be
worn when working with this material.
Flammability: Not flammable under conditions of use
SAFE HANDLING INFORMATION
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse.
Storage and
Protect against physical damage. Avoid dust formation and control ignition sources. Isolate
Transport:
from incompatible substances. Keep in a tightly closed container, stored in a cool, dry,
ventilated area. Protect against physical damage.
Remove all sources of ignition. Ventilate area of leak or spill. Clean-up personnel may require
Spills and Disposal:
protection from inhalation of dust. Spills: Clean up spills in a manner that does not disperse
dust into the air. Use nonsparking tools. Pick up spill for recovery or disposal and place in a
closed container. Disposal: Whatever cannot be saved for recovery may be burned in an
approved incinerator or disposed of in an approved waste facility.
As in any fire, wear a self-contained breathing apparatus in pressure-demand and full
Fire/Explosion
protective gear. During a fire, irritating and highly toxic gases may be generated by thermal
Hazard:
decomposition or combustion. Use extinguishing media most appropriate for the surrounding
fire. Methylene blue does not burn; it is not considered to be a fire hazard.
Page 3 of 3
Methylene Blue
OTHER INFORMATION
Caustic alkali, dichromates, strong oxidising agents, alkali iodides, strong reducing agents.
Incompatibilities
(Materials to avoid)
Oral rat LD50: 1180mg/kg Mutation references cited. Animal reproductive effects cited.
Animal Toxicity
Data:
The information published in this Material Safety Data Sheet has been compiled from data in various technical
publications. It is the user鈥檚 responsibility to determine the suitability of this information for adoption of necessary
safety precautions. We reserve the right to revise material Safety Data Sheets as new information becomes available.
Copies may be made for non-profit use.
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