MATERIAL SAFETY DATA SHEET
Date Printed: 02/23/2006
Date Updated: 01/31/2006
Version 1.5
Section 1 - Product and Company Information
Product Name CADMIUM, REAGENTPLUSTM, >=99% 5-20
MESH
Product Number 265330
Brand SIAL
Company World Precision Instruments, Inc.
Street Address 175 Sarasota Center Blvd.
City, State, Zip, Country Sarasota FL 34240 US
Technical Phone: 941-371-1003
Emergency Phone: 941-371-1003
Fax: 941-377-5428
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
CADMIUM, POWDER 7440-43-9 Yes
Formula Cd
Synonyms Cadmium (ACGIH:OSHA) * Cadmium dust fume (OSHA) *
Cadmium powder * C.I. 77180 * Colloidal cadmium *
Kadmium (German)
RTECS Number: EU9800000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Toxic.
May cause cancer. Very toxic by inhalation, in contact with skin
and if swallowed.
Danger: Can cause lung and kidney disease. Cancer hazard.
HMIS RATING
HEALTH: 3*
FLAMMABILITY: 0
REACTIVITY: 0
NFPA RATING
HEALTH: 3
FLAMMABILITY: 0
REACTIVITY: 0
*additional chronic hazards present.
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
Section 5 - Fire Fighting Measures
FLASH POINT
N/A
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Carbon dioxide. Dry chemical powder.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Ventilate
area and wash spill site after material pickup is complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Avoid contact and inhalation. Avoid prolonged or
repeated exposure.
STORAGE
Suitable: Keep tightly closed. Store in a dry area. Store under
nitrogen.
SPECIAL REQUIREMENTS
Air sensitive.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
PERSONAL PROTECTIVE EQUIPMENT
Other: Wear appropriate government approved respirator,
chemical-resistant gloves, safety goggles, other protective
clothing.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Discard contaminated clothing and
shoes.
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EXPOSURE LIMITS, RTECS
Country Source Type Value
USA ACGIH TWA 0.01 MG(CD)/M3
USA MSHA Standard-air TWA 0.2 MG/M3
USA OSHA. PEL SEE CFR 29,1910.1027
New Zealand OEL
Remarks: check ACGIH TLV
USA NIOSH LOWEST FEASIBLE CONC.
EXPOSURE LIMITS
Country Source Type Value
Poland Polan NDS NDS 0.01 MG/M3 0.01 MG/M3
Poland Polan NDSCh NDSC- -
Poland Polan NDSP NDSP - -
Section 9 - Physical/Chemical Properties
Appearance Color: Slightly grey
Form: Coarse powder
Property Value At Temperature or Pressure
Molecular Weight 112.4 AMU
pH N/A
BP/BP Range 765 掳C
MP/MP Range 320.9 掳C
Freezing Point N/A
Vapor Pressure N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density 8.65 g/cm3
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point N/A
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index N/A
Optical Rotation N/A
Miscellaneous Data N/A
Solubility N/A
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Materials to Avoid: Oxidizing agents, Acids.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Nature of decomposition products
not known.
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HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Absorption: May be harmful if absorbed through the skin.
Inhalation: May be fatal if inhaled.
Ingestion: Harmful if swallowed.
TARGET ORGAN(S) OR SYSTEM(S)
Kidneys. Lungs.
SIGNS AND SYMPTOMS OF EXPOSURE
Damage to the lungs. Damage to the kidneys. Prolonged exposure
can cause: Lung irritation, chest pain, and edema which may be
fatal. Stomach pains, vomiting, diarrhea.
TOXICITY DATA
Oral
Rat
225 mg/kg
LD50
Inhalation
Human
39 mg/m3
LCLO
Remarks: Cardiac:Other changes. Vascular:Thrombosis distant from
injection site. Lungs, Thorax, or Respiration:Respiratory
depression.
Oral
Rat
2330 mg/kg
LD50
Inhalation
Rat
25 mg/m3
LC50
Remarks: Lungs, Thorax, or Respiration:Dyspnea.
Oral
Mouse
890 mg/kg
LD50
Intraperitoneal
Mouse
5700 UG/KG
LD50
CHRONIC EXPOSURE - CARCINOGEN
Result: Carcinogen.
Species: Woman
Route of Application: Inhalation
Dose: 129 UG/M3
Exposure Time: 20Y-
Frequency: C
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Result: Lungs, Thorax, or Respiration:Tumors.
Tumorigenic:Carcinogenic by RTECS criteria.
Species: Rat
Route of Application: Subcutaneous
Dose: 3372 UG/KG
Result: Tumorigenic:Carcinogenic by RTECS criteria.
Tumorigenic:Tumors at site or application.
Species: Rat
Route of Application: Intramuscular
Dose: 40 MG/KG
Exposure Time: 4W
Frequency: I
Result: Musculoskeletal:Tumors. Tumorigenic:Tumors at site or
application. Tumorigenic:Carcinogenic by RTECS criteria.
Species: Rat
Route of Application: Unreported
Dose: 1200 MG/KG
Result: Tumorigenic Effects: Testicular tumors.
Tumorigenic:Equivocal tumorigenic agent by RTECS criteria.
Tumorigenic:Tumors at site or application.
Species: Rat
Route of Application: Intramuscular
Dose: 70 MG/KG
Result: Tumorigenic:Tumors at site or application.
Blood:Lymphomas including Hodgkin's disease.
Tumorigenic:Equivocal tumorigenic agent by RTECS criteria.
Species: Rat
Route of Application: Intramuscular
Dose: 63 MG/KG
Result: Tumorigenic:Equivocal tumorigenic agent by RTECS
criteria. Blood:Lymphomas including Hodgkin's disease.
Tumorigenic:Tumors at site or application.
Species: Rat
Route of Application: Intramuscular
Dose: 45 MG/KG
Exposure Time: 4W
Frequency: I
Result: Tumorigenic:Neoplastic by RTECS criteria.
Musculoskeletal:Tumors. Tumorigenic:Tumors at site or
application.
OSHA CARCINOGEN LIST
Rating: cancer hazard
IARC CARCINOGEN LIST
Rating: Group 1
NTP CARCINOGEN LIST
Rating: Known to be carcinogenic.
ACGIH CARCINOGEN LIST
Rating: A2
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CHRONIC EXPOSURE - TERATOGEN
Species: Rat
Dose: 220 MG/KG
Route of Application: Oral
Exposure Time: (1-22D PREG)
Result: Effects on Embryo or Fetus: Other effects to embryo.
Species: Rat
Dose: 23 MG/KG
Route of Application: Oral
Exposure Time: (1-22D PREG)
Result: Specific Developmental Abnormalities: Blood and
lymphatic system (including spleen and marrow).
Species: Rat
Dose: 1250 UG/KG
Route of Application: Intravenous
Exposure Time: (14D PREG)
Result: Specific Developmental Abnormalities: Urogenital system.
Specific Developmental Abnormalities: Body wall.
Species: Rat
Dose: 1250 UG/KG
Route of Application: Intravenous
Exposure Time: (9D PREG)
Result: Specific Developmental Abnormalities: Eye, ear. Specific
Developmental Abnormalities: Central nervous system.
Species: Rat
Dose: 8 MG/KG
Route of Application: Intravenous
Exposure Time: (8-15D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus).
Species: Mouse
Dose: 448 MG/KG
Route of Application: Oral
Exposure Time: (MULTIGENERATIONS)
Result: Effects on Embryo or Fetus: Fetal death. Effects on
Embryo or Fetus: Fetotoxicity (except death, e.g., stunted
fetus).
Species: Mouse
Dose: 1686 UG/KG
Route of Application: Intraperitoneal
Exposure Time: (7D PREG)
Result: Specific Developmental Abnormalities: Central nervous
system.
Species: Hamster
Dose: 2 MG/KG
Route of Application: Parenteral
Exposure Time: (8D PREG)
Result: Specific Developmental Abnormalities: Craniofacial
(including nose and tongue).
CHRONIC EXPOSURE - MUTAGEN
Species: Mouse
Dose: 6 UMOL/L
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Cell Type: Embryo
Mutation test: Micronucleus test
Species: Hamster
Dose: 1 UMOL/L
Cell Type: ovary
Mutation test: Cytogenetic analysis
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 155 MG/KG
Route of Application: Oral
Exposure Time: (13W MALE/13W PRE-3W PREG)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain). Effects on Newborn: Behavioral.
Species: Rat
Dose: 21500 UG/KG
Route of Application: Oral
Exposure Time: (MULTIGENERATIONS)
Result: Effects on Fertility: Pre-implantation mortality (e.g.,
reduction in number of implants per female; total number of
implants per corpora lutea). Effects on Newborn: Germ cell
effects (in offspring).
Species: Rat
Dose: 1124 UG/KG
Route of Application: Intraperitoneal
Exposure Time: (1D MALE)
Result: Paternal Effects: Spermatogenesis (including genetic
material, sperm morphology,motility, and count).
Species: Rat
Dose: 250 UG/KG
Route of Application: Subcutaneous
Exposure Time: (19D PREG)
Result: Effects on Newborn: Biochemical and metabolic.
Species: Mouse
Dose: 1700 MG/KG
Route of Application: Oral
Exposure Time: (8-12D PREG)
Result: Effects on Newborn: Growth statistics (e.g., reduced
weight gain). Effects on Newborn: Viability index (e.g., # alive
at day 4 per # born alive).
Section 12 - Ecological Information
No data available.
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Material in the elemental state should be recovered for reuse or
recycling. Observe all federal, state, and local environmental
regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: Cadmium compounds
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UN#: 2570
Class: 6.1
Packing Group: Packing Group I
Hazard Label: Toxic substances.
PIH: Not PIH
IATA
Proper Shipping Name: Cadmium compound
IATA UN Number: 2570
Hazard Class: 6.1
Packing Group: I
Section 15 - Regulatory Information
EU ADDITIONAL CLASSIFICATION
Symbol of Danger: T
Indication of Danger: Toxic.
R: 45-20/21/22
Risk Statements: May cause cancer. Harmful by inhalation, in
contact with skin and if swallowed.
S: 53-36-45
Safety Statements: Avoid exposure - obtain special instructions
before use. Wear suitable protective clothing. In case of
accident or if you feel unwell, seek medical advice immediately
(show the label where possible).
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Toxic.
Risk Statements: May cause cancer. Very toxic by inhalation, in
contact with skin and if swallowed.
Safety Statements: Avoid exposure - obtain special instructions
before use. Do not breathe dust. In case of contact with eyes,
rinse immediately with plenty of water and seek medical advice.
After contact with skin, wash immediately with plenty of water.
Wear suitable protective clothing, gloves, and eye/face
protection. In case of accident or if you feel unwell, seek
medical advice immediately (show the label where possible).
US Statements: Danger: Can cause lung and kidney disease. Cancer
hazard.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: Yes
DEMINIMIS: 0.1 %
NOTES: This product is subject to SARA section 313 reporting
requirements.
TSCA INVENTORY ITEM: Yes
UNITED STATES - STATE REGULATORY INFORMATION
CALIFORNIA PROP - 65
California Prop - 65: This product is or contains chemical(s)
known to the state of California to cause cancer.
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
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DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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