Material Safety Data Sheet
MSDS 007
Rev: D
Product: CIDEX Plus 28 Day Solution
Issue date: 12/05/03
1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE
COMPANY/UNDERTAKING
Supplier:
Advanced Sterilization Products
33 Technology Drive
Irvine, CA 92618
1-800-755-5900
Customer service telephone:
(800) 451-8346 or (760) 602-8700 - 24 hrs
Emergency telephone number:
CIDEXPLUS 28 Day Solution
Product name:
2. COMPOSITION/INFORMATION ON INGREDIENTS
The ingredients at their given percentages in this product are not considered hazardous to your health.
Components CAS Number Weight % J&J - OEL Data J&J - OEL Data J&J - OEL Data J&J - PBOEL
(TWA - 8 hr) (STEL): (Ceiling Limit
Value):
Glutaraldehyde 111-30-8 <5 Not Determined Not Determined Not Determined Not Determined
Polyethylene Glycol 25322-68-3 <20 Not Determined Not Determined Not Determined Not Determined
Poloxamer 188 9003-11-6 <5 Not Determined Not Determined Not Determined Not Determined
3. HAZARDS IDENTIFICATION
None
Emergency overview:
None
Properties affecting health:
Principle routes of exposure:
Can irritate the tissues of mouth, esophagus, and other tissues of the digestive
Oral:
system. Symptoms of over exposure can include vomiting, diarrhea and nausea.
Severe irritant / corrosive to the eye.
Eye contact:
May cause skin irritation. May aggravate pre-existing dermatitis
Skin contact:
Ingestion of this material may cause oral thrush, nausea, vomiting, epigastric
Ingestion:
distress, diarrhea, headache, fatigue, dizziness, insomnia, mental confusion, and
impairment.
Inhalation of mist or vapors may be severely irritating to the nose, throat and lungs.
Inhalation:
This product may cause eye, skin or respiratory irritation.
Physico-chemical properties:
Hazard information:
None.
Target organ effects:
This material is not reported to cause reproductive effects in humans
Reproductive effects:
This product is not know to produce mutagenic effects in humans
Mutagenic effects:
May cause sensitization by inhalation and skin contact. Glutaraldehyde has been
Sensitization:
reported to cause occupational asthma and may aggravate pre-existing asthma,
inflammatory or fibrotic pulmonary disease.
Company: ADVANCED STERLIZATION PRODUCTS Product code: ASPCIDEXPLUS
Product name: CIDEXPLUS 28 Day Solution CO-29503-3
Page 1 of 7
Carcinogenicity rating:
Components CAS Number NTP: IARC: California
J&J:
Proposition 65 List:
Glutaraldehyde 111-30-8 Not Determined Not Determined Not Determined Not Determined
Polyethylene Glycol 25322-68-3 Not Determined Not Determined Not Determined Not Determined
Poloxamer 188 9003-11-6 Not Determined Not Determined Not Determined Not Determined
None.
Signs and symptoms:
Inhalation of vapor may cause asthma-like symptoms (chest discomfort and
Medical conditions
tightness, difficulty with breathing) as well as aggravate pre-existing asthma and
aggravated by exposure:
inflammatory or fibrotic pulmonary disease.
4. FIRST AID MEASURES
In the case of contact with eyes, rinse immediately with plenty of water for 15
Eye contact:
minutes and seek medical attention.
Call a physician or Poison Control Center immediately
Ingestion:
Move to fresh air immediately. If experiencing difficulty breathing, seek medical
Inhalation:
attention.
Rinse with plenty of water.
Skin contact:
After contact with skin wash immediately with plenty of water. . Immediately remove
contaminated clothing and shoes. Wash contaminated clothing before reuse. Seek
medical attention if symptoms appear.
None.
Protection of first-aiders:
Probable damage to the mucosa from oral exposure may contraindicate the use of
Notes to physician:
gastric lavage
5. FIRE-FIGHTING MEASURES
Unknown on product.
Flash point (掳F):
Unknown on product.
Flash point (掳C):
Unknown on product.
Autoignition temperature:
Unknown on product.
Flammable limits in air - lower (%):
Health: 2 Flammability: 0 Reactivity: 0
NFPA rating:
HMIS/ NFPA rating and classification:
Fire fighting information:
Use water, dry chemical, carbon dioxide or chemical foam.
Suitable extinguishing media:
None.
Extinguishing media which must not be used for
safety reasons:
None.
Specific methods:
Company: ADVANCED STERLIZATION PRODUCTS Product code: ASPCIDEXPLUS
Product name: CIDEXPLUS 28 Day Solution CO-29503-3
Page 2 of 7
Wear self-contained breathing apparatus for fire fighting if
Special protective equipment for firefighters:
necessary.
Carbon dioxide and carbon monoxide
Hazardous combustion products:
None.
Explosivity:
Explosion limits:
None.
lower:
None.
upper:
6. ACCIDENTAL RELEASE MEASURES
Wear eye and skin protection while handling material for clean-up.
Personal precautions:
(Wear nitrile or latex gloves.)
Responders should wear gloves, goggles and suitable body protection. Where there
is a risk of product contact with shoes, chemical resistant shoe coverings are
recommended.
No special environmental precautions required.
Environmental precautions:
Clean-up methods - small spillage
Methods for cleaning up:
Neutralize with a mixture of equal amounts of household ammonia and water.
Flush with water.
Clean-up methods - large spillage
Contain spill by placing suitable absorbent material around the edges of the spill and
work inward. Carefully scoop up into waste container for disposal.
For each estimated gallon of spill disperse about 228g of sodium bisulfite powder on
spill. Thoroughly blend sodium bisulfite into CIDEX Solution. Allow 5 minutes for
deactivation.
7. HANDLING AND STORAGE
Handling:
No special technical protective measures required.
Technical measures/precautions:
Use only in well-ventilated areas. Avoid contact with skin
Safe handling advice:
and eyes. Eye and skin protection recommended. Wear
chemical resistant gloves.
Storage:
This product should be stored between 59掳F (15掳C) and
Technical measures/storage conditions:
86掳F (30掳C)
Avoid contact with strong acids and bases.
Incompatible products:
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Ensure adequate ventilation.
Engineering controls:
Rooms where CIDEX Solution is used should have a minimum of 10 air exchanges
per hour.
Eye protection recommended during production of product. For routine use, wear
Eye protection:
approved chemical splash goggles. Where there is risk of product splashing into
eyes, an independant faceshield must be worn.
Protective gloves recommended when manufacturing product. Wear chemical
Hand protection:
resistant gloves. Gloves should be changed frequently during use of product. Do not
use neoprene or polyvinyl chloride (vinyl) gloves as glutaraldehyde may be rapidly
absorbed by these materials.
Company: ADVANCED STERLIZATION PRODUCTS Product code: ASPCIDEXPLUS
Product name: CIDEXPLUS 28 Day Solution CO-29503-3
Page 3 of 7
Wear suitable protective clothing. Wear chemical resistant lab coat.
Skin and body protection
None required.
Respiratory protection:
None required.
Other/general protection:
9. PHYSICAL AND CHEMICAL PROPERTIES
colorless
Appearance:
Liquid
Physical state:
3.2-4.3 (unactivated) 7.5-8.1 (activated)
pH:
Characteristic aldehyde odor
Odor:
212
Boiling temperature (潞F):
100
Boiling temperature (潞C):
0
Freezing point/range (潞C):
32
Freezing point/range (潞F):
1.029g/cc
Specific gravity:
1.1
Vapor density:
1.0
Evaporation rate:
Completely soluble
Water solubility:
10. STABILITY AND REACTIVITY
Stable under recommended storage conditions.
Chemical stability:
Hazardous polymerization does not occur.
Hazardous polymerization:
None.
Hazardous decomposition products:
Strong acids and bases.
Materials to avoid:
Temperatures above 40掳C for an extended period of time.
Conditions to avoid:
11. TOXICOLOGICAL INFORMATION
Acute toxicity
4250mg/kg
LD50 Oral Rat (mg/kg):
>2000mg/kg
LD50 Dermal Rabbit (mg/kg):
Local effects
Unknown on product.
Oral:
Severe irritant and corrosive to the eye when tested in animals..
Eye irritation
Skin contact may aggravate pre-existing dermatitis.
Skin irritation:
Inhalation of vapor may cause asthma-like symptoms as well as aggravate pre-
Inhalation:
existing asthma and inflammatory or fibrotic pulmonary disease
Chronic toxicity
Unknown on product.
Oral:
Unknown on product.
Inhalation:
Unknown on product.
Dermal:
Subchronic toxicity
Subchronic drinking water studies in rats, mice and dogs using glutaraldehyde
Oral:
concentrations of up to 1000ppm showed no evidence for any target organ toxixcity.
Unknown on product.
Dermal:
Company: ADVANCED STERLIZATION PRODUCTS Product code: ASPCIDEXPLUS
Product name: CIDEXPLUS 28 Day Solution CO-29503-3
Page 4 of 7
Specific effects
Unknown on product.
Corrosive effects:
When administered to the skin of guinea pigs using the maximization method the
Sensitization:
compound was found to be a mild sensitizer.
None.
Target organ effects:
In vitro studies have given results varying from no genotoxicity to equivocal or weakly
Mutagenic effects:
positive activity; however, all in vivo studies have been uniformly negative.
Was not a reproductive effector in animals.
Reproductive effects:
This material is not reported to cause reproductive effects in humans
At maternally non-toxic doses, glutaraldehyde does not produce fetotoxic, embryo
Developmental effects:
toxic nor teratogenic effects.
No carcinogenic effects were observed in mice or rats.
Carcinogenic effects:
12. ECOLOGICAL INFORMATION
Ecotoxicity:
This product has no known eco-toxicological effects.
Ecotoxicity effects:
This product has no known aquatic toxicological effects.
Aquatic toxicity effects:
Unknown on product.
Mobility:
Unknown on product.
Persistence / degradability:
Unknown on product.
Bioaccumulation:
Unknown on product.
Degradation:
13. DISPOSAL CONSIDERATIONS
Waste disposal must be in accordance with appropriate US,
Waste from residues / unused products:
Federal, State and International regulations. This product, if
unaltered by use, may be disposed of by treatment at a
permitted facility or as advised by your local hazardous
waste regulatory authority.
None.
Contaminated packaging:
Clean-up methods - small spillage
Methods for cleaning up:
Neutralize with a mixture of equal amounts of household
ammonia and water.
Flush with water.
Clean-up methods - large spillage
Contain spill by placing suitable absorbent material around
the edges of the spill and work inward. Carefully scoop up
into waste container for disposal.
For each estimated gallon of spill disperse about 228g of
sodium bisulfite powder on spill. Thoroughly blend sodium
bisulfite into CIDEX Solution. Allow 5 minutes for
deactivation.
14. TRANSPORT INFORMATION
DOT:
Not applicable
DOT UN-No:
Not regulated
DOT shipping name:
Not applicable
Hazard class:
Not applicable
Subsidiary risk (hazard class):
Not applicable
Packing group:
Not applicable
DOT reportable quantity (lbs):
Company: ADVANCED STERLIZATION PRODUCTS Product code: ASPCIDEXPLUS
Product name: CIDEXPLUS 28 Day Solution CO-29503-3
Page 5 of 7
IMO/IMDG:
Not applicable
Hazard class:
Not applicable
IMDG page:
Not applicable
IMDG-labels:
Not applicable
Packing group:
Not applicable
MFAG table No.:
Not regulated
Proper shipping name:
Not applicable
UN/Id No.:
ADR/RID:
Not applicable
Hazard class/packing group:
Not applicable.
Item:
Not applicable
ADR/RID-labels:
Not applicable
UN/Id No.:
Not regulated
Proper shipping name:
Not applicable
TREM-card:
IATA/ICAO:
Not applicable
Hazard class:
Not applicable
Packing group:
Not regulated
Proper shipping name:
Not applicable
ID/UN No.:
Not applicable
IATA - label:
Not applicable
ERG #
TDG (Canada):
Not applicable
Status:
Not applicable
Packing group:
15. REGULATORY INFORMATION
Components CAS Number Weight % ACGIH TLV (TWA - ACGIH TLV (STEL) ACGIH TLV (Ceiling
8hr) Limits)
3
Glutaraldehyde 111-30-8 <5 0.2 mg/m
Components CAS Number Weight % OSHA (TWA - 8hr) OSHA (STEL) OSHA (Ceiling
Limits)
3
Glutaraldehyde 111-30-8 <5 0.8 mg/m
SARA (311, 312) hazard class:
None
Immediate health:
None
Delayed health:
None
Fire:
None
Sudden Release of
Pressure Hazard:
None
Reactivity:
Components CAS Number Weight % New Jersey Pennsylvania Massachusett Connecticut Michigan Critical
RTK List: RTK List: s RTK List: Hazardous List:
Material List:
Glutaraldehyde 111-30-8 <5 Listed. Listed. Listed.
Listed under TSCA: Yes
TSCA inventory list:
WHMIS:
None
WHMIS trade secret:
None
WHMIS hazard class:
Listed on DSL: Yes
Canada DSL inventory list:
Company: ADVANCED STERLIZATION PRODUCTS Product code: ASPCIDEXPLUS
Product name: CIDEXPLUS 28 Day Solution CO-29503-3
Page 6 of 7
Notes:
1. SARA = Superfund Amendments and the Reauthorization Act.
2. CERCLA = Comprehensive Environmental Response, Compensations and Liability Act.
3. FIFRA = Federal Insecticide, Fungicide and Rodenticide Act
4. TSCA = Toxic Substance Control Act
5. WHMIS = Canadian Workplace Hazardous Materials Information System
6. This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and
the MSDS contains all of the information required by the CPR.
16. OTHER INFORMATION
This data sheet contains changes from the previous version in section(s):
None
None
Additional advice
None
Literary Reference:
North American Format - U.S. and Canada
MSDS format:
This Material Safety Data Sheet was prepared in accordance with OSHA 29 CFR
1910.1200.
Disclaimer:
The information and recommendations contained herein are based upon tests believed to be reliable. However, Johnson
and Johnson does not guarantee their accuracy or completeness NOR SHALL ANY OF THIS INFORMATION
CONSTITUTE A WARRANTY, WHETHER EXPRESSED OR IMPLIED, AS TO THE SAFETY OF THE GOODS, THE
MERCHANTABILITY OF THE GOODS, OR THE FITNESS OF THE GOODS FOR A PARTICULAR PURPOSE.
Adjustment to conform to actual conditions of usage maybe required. Johnson and Johnson assumes no responsibility
for results obtained or for incidental or consequential damages, including lost profits arising from the use of these data.
No warranty against infringement of any patent, copyright or trademark is made or implied.
End of Safety Data Sheet
Company: ADVANCED STERLIZATION PRODUCTS Product code: ASPCIDEXPLUS
Product name: CIDEXPLUS 28 Day Solution CO-29503-3
Page 7 of 7
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