1
1
1
1 0
0
Material Safety Data Sheet
6-MERCAPTOPURINE, MONOHYDRATE
1: Chemical Product and Company Identification
Product Name: 6-MERCAPTOPURINE, MONOHYDRATE
Contact information:
Catalog Code: 714161, 714162, 714163
bioWORLD
CAS#: 6112-76-1 4150 Tuller Rd
Suite 228, Dublin, OH 43017, USA
RTECS: UP0400000
For information, call: 614-792-8680
TSCA: TSCA 8(b) inventory: No products were found. Fax Number: 614-792-8685
Order Online:www.bio-world.com
CI#: Not available.
E-mail : save@bio-world.com
Synonym: 1,7-Dihydro-6H-purine-6-thione, monohydrate; 6-
Mercaptopurine monohydrate; 6H-Purine-6-thione, 1,7-Dihydro-, In case of a chemical emergency, contact local
monohydrate. hospital.
Chemical Name: Purine-6-thiol, monohydrate For non-emergency assistance,call: 1-800-860-9729
Chemical Formula: C5H4N4S路H2O
2: Composition and Information on Ingredients
Composition:
Name CAS# % by Weight
6-MERCAPTOPURINE, MONOHYDRATE 6112-76-1 100
Toxicological Data on Ingredients:
LD50 (Oral, Mouse): 1250 mg/kg
3: Hazards Identification
Potential Acute Health Effects: Harmful
Harmful if swallowed. Irritating to eyes, respiratory system and skin.
Target organ(s): Liver Bone marrow
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Suspected carcinogen.
1
MUTAGENIC EFFECTS: Mutagenic for bacteria and/or yeast.
TERATOGENIC EFFECTS: Suspected teratogen.
DEVELOPMENTAL TOXICITY: Not available.
4: First Aid Measures
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Get medical attention if irritation occurs.
Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation
develops.
Serious Skin Contact: Not available.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Serious Inhalation: Not available.
Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing
such as a collar, tie, belt or waistband.
Serious Ingestion: Not available.
5: Fire and Explosion Data
Flammability of the Product: May be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Flash Points: Not available.
Flammable Limits: Not available.
Product of Combustion: Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides.
Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence of heat.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available.
Slightly explosive in presence of open flames and sparks.
Fire Fighting Media and Instructions:
SMALL FIRE: Dry chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards: As with most organic solids, fire is possible at elevated temperatures
Special Remarks on Explosion Hazards: Fine dust dispersed in air in sufficient concentrations, and in the presence of
an ignition source is a potential dust explosion hazard.
6: Accidental Release Measures
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
2
spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading
water on the contaminated surface and allow to evacuate through the sanitary system.
7: Handling and Storage
Precautions: Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
ingest. Do not breathe dust. Wear suitable protective clothing. If ingested, seek medical advice immediately and show the
container or the label. Keep away from incompatibles such as oxidizing agents, acids, alkalis.
Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area.
8: Exposure Controls/Personal Protection
Engineering Controls: Safety shower and eye bath. Mechanical exhaust required.
Personal Protection: Respiratory: Niosh/msha鈭抋pproved respirator.
Hand: Compatible chemical鈭抮esistant gloves.
Eye:Chemical safety goggles.
Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Dust respirator. Boots. Gloves.
Exposure Limits: Not available.
9: Physical and Chemical Properties
Physical State and Appearance: Solid. (Powdered solid.)
Odor: Not available.
Taste: Not available.
Molecular Weight: 170.19 g/mole
Color: Yellow.
pH(1% soln/water): Not available.
Boiling Point: Not available.
Melting Point: 313 掳C (595.4 掳F)
Critical Temperature: Not available.
Specific Gravity: Not available.
Vapour Pressure: Not available.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: Not available.
Solubility: Insoluble in cold water, hot water. Soluble in hot ethanol, in alkaline solutions with slow decomposition.
3
10: Stability and Reactivity Data
Stability: Stable.
Instability Temperature: Not available.
Conditions of Instability: Excess heat, incompatible materials.
Incompatibility with various substances: Reactive with oxidizing agents, acids, alkalis.
Corrosivity: Not available.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
11:Toxicological Information
Routes of Entry: Skin contact. Eye contact. Inhalation. Ingestion.
Toxicity to Animals:
LD50 (Oral, Mouse): 1250 mg/kg
Chronic Effects on Humans: MUTAGENIC EFFECTS: Mutagenic for bacteria and/or yeast.
May cause damage to the following organs: blood, liver, immune system, bone marrow.
Other Toxic Effects on Humans: Skin:Causes skin irritation. May be harmful if absorbed through the skin.
Eye: Causes eye irritation.
Inhalation: May be harmful if inhaled. Material is irritating to mucous membranes and upper respiratory tract.
Ingestion: Harmful if swallowed.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: May affect genetic material (mutagenic).
May cause adverse reproductive effects and birth defects (teratogenic).
May cause cancer based on animal test data.
Special Remarks on other Toxic Effects on Humans: Not available.
12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Product of Biodegradation: Possibly hazardous short term degradation products are not likely. However, long term
degradation products may arise.
Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product itself.
Special Remarks on the Products of Biodegradation: Not available.
4
13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations.
14: Transport Information
DOT Classification: Not a DOT controlled material.
Identification: Not available.
Special Provisions for Transport: Not available.
15: Other Regulatory Information
Federal and State Regulations: TSCA 8(b) inventory: No products were found.
Other Regulations: EUROPEAN INFORMATION
Caution: substance not yet fully tested.
R 22
Harmful if swallowed.
R 36/37/38
Irritating to eyes, respiratory system and skin.
S 22
Do not breathe dust.
S 36/37/39
Wear suitable protective clothing, gloves and eye/face protection.
S 45
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Other Classifications:
WHMIS(Canada): Not available.
DSCL(EEC): R22- Harmful if swallowed.
S24/25- Avoid contact with skin and eyes.
HMIS(U.S.A):
Health Hazard: 1
Fire Hazard: 1
Reactivity: 0
Personal Protection:
National Fire Protection Association (U.S.A):
Health: 1
Flammability: 1
Reactivity: 0
Specific hazard:
5
Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Safety goggles.
16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 21/07/2006 2:42:54 PM
Last Updated: 10/08/2006 4:09:39 PM
Disclaimer
This product is offered by bioWORLD for research, laboratory or further manufacturing use. Not for human use or
consumption.
The information above is believed to be accurate and represents the best information currently available to us. However,we
make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we
assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
information for their particular purposes.In no event shall Bio-World.com be liable for any claims, losses, or damages of any
third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoever arising,
even if Bio-World.com has been advised of the possibility of such damages.
6
|