2
0
0
2 0
0
Material Safety Data Sheet
NICOTINIC ACID
1: Chemical Product and Company Identification
Product Name: NICOTINIC ACID
Contact information:
Catalog Code: 714170, 714171
bioWORLD
4150 Tuller Rd
CAS#: 59-67-6
Suite 228, Dublin, OH 43017, USA
RTECS: QT0525000
For information, call: 614-792-8680
Fax Number: 614-792-8685
TSCA: TSCA 8(b) inventory: Nicotinic Acid.
Order Online:www.bio-world.com
CI#: Not available.
E-mail : save@bio-world.com
Synonym: Pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid;
In Case of a chemical emergency, call CHEMTREC
Niacin; Niacinamide;Vitaplex N. .
(24 hours a day) at 1-800-424-9300
Chemical Name: Pyridine-3-carboxylic acid
For non-emergency assistance,call: 1-800-860-9729
Chemical Formula: C6H5NO2
2: Composition and Information on Ingredients
Composition:
Name CAS# % by Weight
NICOTINIC ACID 59-67-6 99
Toxicological Data on Ingredients:
LD50 (Oral, Rat): > 5,000 mg/kg
LD50 (Skin, Rat): > 2,000 mg/kg
LD50 (Intraperitoneal, Rat): 730 mg/kg
LD50 (Subcutaneous, Rat): 5 g/kg
LD50 (Oral, Mouse): 3720 mg/kg
3: Hazards Identification
Potential Acute Health Effects: Irritant.
Irritating to eyes, respiratory system and skin.
Potential Chronic Health Effects:
1
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
4: First Aid Measures
Eye Contact: In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.
Skin Contact: In case of contact, immediately wash skin with soap and copious amounts of water.
Serious Skin Contact: Not available.
Inhalation: If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Serious Inhalation: Not available.
Ingestion: If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Serious Ingestion: Not available.
5: Fire and Explosion Data
Flammability of the Product: May be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Flash Points: 193 掳C (379.4 掳F)
Flammable Limits: Not available.
Product of Combustion: Carbon monoxide, Carbon dioxide, Nitrogen oxides.
Fire Hazards in Presence of Various Substances: Not available.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Dry chemical powder.
LARGE FIRE: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Not available.
6: Accidental Release Measures
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
2
Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading
water on the contaminated surface and allow to evacuate through the sanitary system.
7: Handling and Storage
Precautions: Do not breathe dust. Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeated exposure.
Storage: Keep tightly closed.
8: Exposure Controls/Personal Protection
Engineering Controls: Safety shower and eye bath. Mechanical exhaust required.
Personal Protection: Respiratory: Government approved respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
Personal Protection in Case of a Large Spill: Safety goggles. Lab coat. Dust respirator. Gloves.
Exposure Limits: Not available.
9: Physical and Chemical Properties
Physical State and Appearance: Solid Powder.
Odor: Not available.
Taste: Not available.
Molecular Weight: 123.11 g/mole
Color: White.
pH(1% soln/water): Not available.
Boiling Point: Not available.
Melting Point: 234 掳C
Critical Temperature: Not available.
Specific Gravity: 1.473
Vapour Pressure: Not available.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: Not available.
Solubility: Soluble in water.
3
10: Stability and Reactivity Data
Stability: Stable.
Instability Temperature: Not available.
Conditions of Instability: Not available.
Incompatibility with various substances: Strong oxidizing agents.
Corrosivity: Not available.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
11:Toxicological Information
Routes of Entry: Skin Contact. Eye Contact. Inhalation. Ingestion.
Toxicity to Animals:
LD50 (Oral, Rat): > 5,000 mg/kg
LD50 (Skin, Rat): > 2,000 mg/kg
LD50 (Intraperitoneal, Rat): 730 mg/kg
LD50 (Subcutaneous, Rat): 5 g/kg
LD50 (Oral, Mouse): 3720 mg/kg
Chronic Effects on Humans: Not available.
Other Toxic Effects on Humans: Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation.
Inhalation: Material is irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: Not available.
Special Remarks on other Toxic Effects on Humans: Not available.
12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Product of Biodegradation: Not available.
Toxicity of the Products of Biodegradation: Not available.
Special Remarks on the Products of Biodegradation: Not available.
4
13: Disposal Considerations
Waste Disposal: Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the
material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe
all federal, state, and local environmental regulations.
14: Transport Information
DOT Classification: Not a DOT controlled material.
Identification: Not available.
Special Provisions for Transport: Not available.
15: Other Regulatory Information
Federal and State Regulations: TSCA 8(b) inventory: Nicotinic Acid
Other Regulations: EU ADDITIONAL CLASSIFICATION
Symbol of Danger: Xi
Indication of Danger: Irritant.
R: 36/37/38
Risk Statements: Irritating to eyes, respiratory system and skin.
S: 26 36
Safety Statements: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear
suitable protective clothing.
Other Classifications:
WHMIS(Canada): Not available.
DSCL(EEC): Not available.
HMIS(U.S.A):
Health Hazard: 2
Fire Hazard: 0
Reactivity: 0
Personal Protection:
National Fire Protection Association (U.S.A):
Health: 2
Flammability: 0
Reactivity: 0
Specific hazard:
Protective Equipment: Gloves. Lab coat. Dust respirator. Safety goggles.
16: Other Information
5
References: Not available.
Other Special Considerations: Not available.
Created: 28/07/2006 10:25:58 AM
Last Updated: 31/07/2006 4:11:05 PM
Disclaimer
This product is offered by bioWORLD for research, laboratory or further manufacturing use. Not for human use or
consumption.
The information above is believed to be accurate and represents the best information currently available to us. However,we
make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we
assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
information for their particular purposes.In no event shall Bio-World.com be liable for any claims, losses, or damages of any
third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoever arising,
even if Bio-World.com has been advised of the possibility of such damages.
6
|