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Material Safety Data Sheet
RIBAVIRIN
1: Chemical Product and Company Identification
Product Name: RIBAVIRIN
Contact information:
Catalog Code: 714188
bioWORLD
CAS#: 36791-04-5 4150 Tuller Rd
Suite 228, Dublin, OH 43017, USA
RTECS: XZ4250000
For information, call: 614-792-8680
TSCA: TSCA 8(b) inventory : No products were found. Fax Number: 614-792-8685
Order Online:www.bio-world.com
CI#: Not available.
E-mail : save@bio-world.com
Synonym: Icn-1229; Ribamidyl; Ribavirin; 1-beta-D-
Ribofuranosyl-1,2,4-triazole-3-carboxamid e; RTCA; Viramid; In case of a chemical emergency, contact local
Virazole. hospital.
Chemical Name: Ribavirin For non-emergency assistance,call: 1-800-860-9729
Chemical Formula: C8H12N4O5
2: Composition and Information on Ingredients
Composition:
Name CAS# % by Weight
RIBAVIRIN 36791-04-5 >98
Toxicological Data on Ingredients:
LD50 (Oral, Rat): 2700 mg/kg
3: Hazards Identification
Potential Acute Health Effects: Toxic.
May cause harm to the unborn child.
Target organ(s): Blood. Cardiovascular system.
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not available.
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MUTAGENIC EFFECTS: Suspected mutagen.
TERATOGENIC EFFECTS: Suspected teratogen.
DEVELOPMENTAL TOXICITY: Paternal effects.
4: First Aid Measures
Eye Contact: In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.
Skin Contact: In case of contact, immediately wash skin with soap and copious amounts of water.
Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek
medical attention.
Inhalation: If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Serious Inhalation: Not available.
Ingestion: If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Serious Ingestion: Not available.
5: Fire and Explosion Data
Flammability of the Product: Noncombustible.
Auto-Ignition Temperature: Not available.
Flash Points: Not available.
Flammable Limits: Not available.
Product of Combustion: Carbon monoxide, Carbon dioxide, Nitrogen oxides.
Fire Hazards in Presence of Various Substances: Not available.
Explosion Hazards in Presence of Various Substances:
Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Use extinguishing media appropriate to surrounding fire conditions.
LARGE FIRE: Not available.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Not available.
6: Accidental Release Measures
Small Spill: Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site
after material pickup is complete.
Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading
water on the contaminated surface and allow to evacuate through the sanitary system.
7: Handling and Storage
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Precautions: Do not breathe vapor. Do not get in eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
Storage: Keep tightly closed. Store in a cool dry place. Store at 2-8掳C.
8: Exposure Controls/Personal Protection
Engineering Controls: Use only in a chemical fume hood. Safety shower and eye bath.
Personal Protection: Respiratory : Government approved respirator.
Hand: Chemical resistant gloves.
Eye: Safety glasses.
Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Boots. Dust respirator. Gloves.
Exposure Limits: Not available.
9: Physical and Chemical Properties
Physical State and Appearance: Solid.
Odor: Not available.
Taste: Not available.
Molecular Weight: 244.20 g/mole
Color: Not available.
pH(1% soln/water): Not available.
Boiling Point: Not available.
Melting Point: Not available.
Critical Temperature: Not available.
Specific Gravity: Not available.
Vapour Pressure: Not available.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: Not available.
Solubility: Soluble in water.
10: Stability and Reactivity Data
Stability: Stable.
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Instability Temperature: Not available.
Conditions of Instability: Hygroscopic.
Incompatibility with various substances: Not available.
Corrosivity: Not available.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
11:Toxicological Information
Routes of Entry: Skin contact. Eye contact. Ingestion. Inhalation.
Toxicity to Animals:
LD50 (Oral, Rat): 2700 mg/kg
LD50 (Intraperitoneal, Mouse): 1300 mg/kg
Chronic Effects on Humans: Teratogen : Specific Developmental Abnormalities (Musculoskeletal system).
Mutagen: DNA inhibition.
Reproductive Hazard: Paternal Effects (Spermatogenesis (including genetic material, sperm morphology,motility, and
count)).
Other Toxic Effects on Humans: Skin Contact: May cause skin irritation.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and upper respiratory tract.
Multiple Routes: Harmful if swallowed, inhaled, or absorbed through skin.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: Not available.
Special Remarks on other Toxic Effects on Humans: Not available.
12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Product of Biodegradation: Not available.
Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.
Special Remarks on the Products of Biodegradation: Not available.
13: Disposal Considerations
Waste Disposal: Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with
an afterburner and scrubber. Observe all federal, state, and local environmental regulations.
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14: Transport Information
DOT Classification: Not a DOT controlled material.
Identification: Not available.
Special Provisions for Transport: Not available.
15: Other Regulatory Information
Federal and State Regulations: TSCA 8(b) inventory : No products were found.
Other Regulations: EU ADDITIONAL CLASSIFICATION
Symbol of Danger: T
Indication of Danger: Toxic.
R: 61
Risk Statements: May cause harm to the unborn child.
S: 53 22 45
Safety Statements: Avoid exposure - obtain special instructions before use. Do not breathe dust. In case of accident or if you
feel unwell, seek medical advice immediately (show the label where possible).
Other Classifications:
WHMIS(Canada): Not available.
DSCL(EEC): Not available.
HMIS(U.S.A):
Health Hazard: 1
Fire Hazard: 1
Reactivity: 0
Personal Protection: a
National Fire Protection Association (U.S.A):
Health: 1
Flammability: 1
Reactivity: 0
Specific hazard:
Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Safety goggles.
16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 02/09/2006 5:10:20 PM
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Last Updated: 07/09/2006 11:33:54 AM
Disclaimer
This product is offered by bioWORLD for research, laboratory or further manufacturing use. Not for human use or
consumption.
The information above is believed to be accurate and represents the best information currently available to us. However,we
make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we
assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
information for their particular purposes.In no event shall Bio-World.com be liable for any claims, losses, or damages of any
third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoever arising,
even if Bio-World.com has been advised of the possibility of such damages.
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