Creation Date: 03-26-2002
Revision Date: 10-06-2005
Material Safety Data Sheet
.
1. Chemical Product and Company Identification
space
Material Name EPIBATIDINE [125I]-
space
02
Version #
space
NEX358000MC
Item #
space
Laboratory chemical
Product Use
space
PerkinElmer Life and Analytical Sciences
Identification Of The
710 Bridgeport Avenue
Company/Undertaking
Shelton, CT 06484
space
Technical Support 800-762-4000
space
CHEMTREC 800-424-9300
Emergency Telephone
Emergency Phone 800-762-4000
Number
.
2. Composition / Information on Ingredients
space
Hazardous component(s) CAS # Percent PEL TLV
ETHANOL 64-17-5 80 - 90 1000 ppm 1000
space
ACETONITRILE 75-05-8 1 - 2.5 40 ppm 20
space
Non-hazardous component(s) CAS # Percent
WATER 7732-18-5 2.5 - 10
space
[125I]-EPIBATIDINE < 0.01
space
Other components below reportable levels 0.0001 - 0.01
space
.
3. Hazards Identification
space
Emergency Overview
Highly flammable.
Severe eye irritation.
Irritating to respiratory system and skin.
space
.
4. First Aid Measures
space
General advice
In case of feeling unwell: Call a physician immediately.
space
First Aid
Skin contact
Wash off immediately with plenty of water for at least 15 minutes.
space
Eye contact
Rinse immediately with plenty of water for at least 15 minutes. If eye irritation persists, consult a
specialist.
space
Inhalation
Move to fresh air. Oxygen or artificial respiration if needed.
Material ID 4909 Material Name EPIBATIDINE [125I]-
1/ 6
MSDS US
space
Ingestion
Clean mouth with water and drink afterwards plenty of water. Never give anything by mouth to
an unconscious person.
space
.
5. Fire Fighting Measures
space
Suitable extinguishing media
use dry chemical, CO2, water spray or "alcohol" foam
space
Special protective equipment for firefighters
Wear suitable protective equipment
space
Unusual Fire & Explosion Hazards
In the event of fire toxic fumes may be formed.
.
6. Accidental Release Measures
space
Evacuation Procedures
Isolate area. Keep unnecessary personnel away.
space
Personal precautions
Remove all sources of ignition. Ensure adequate ventilation. Use personal protective equipment.
space
Environmental precautions
Do not flush into surface water or sanitary sewer system.
space
Methods for cleaning up
Soak up with inert absorbent material. Clean contaminated surface thoroughly. Keep in suitable and
closed containers for disposal.
space
.
7. Handling and Storage
space
Handling
Use only in area provided with appropriate exhaust ventilation. Wear personal protective
equipment. Do not breathe vapours or spray mist. Avoid contact with skin and eyes. Keep away
from heat and sources of ignition.
space
Storage
Keep away from heat, sparks, and flame. Keep tightly closed in a dry, cool and well-ventilated
place.
space
.
8. Exposure Controls / Personal Protection
space
Exposure Limit Values
ACGIH - Threshold Limits Values - Time Weighted Averages (TLV-TWA)
ACETONITRILE 75-05-8 20 ppm TWA
ETHANOL 64-17-5 1000 ppm TWA
OSHA - Final PELs - Time Weighted Averages (TWAs)
ACETONITRILE 75-05-8 40 ppm TWA; 70 mg/m3 TWA
ETHANOL 64-17-5 1000 ppm TWA; 1900 mg/m3 TWA
space
Exposure Controls
Engineering measures to reduce exposure
Provide adequate ventilation.
space
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin,
eyes and clothing. Keep away from food and drink. Wash hands before breaks and immediately
after handling the product. Contaminated work clothing should not be allowed out of the
workplace.
Material ID 4909 Material Name EPIBATIDINE [125I]-
2/ 6
MSDS US
space
Respiratory protection
Do not inhale aerosol. No personal respiratory protective equipment normally required.
space
Hand protection
solvent-resistant gloves
space
Eye protection
safety glasses with side-shields
space
Skin and body protection
lab coat
space
.
9. Physical & Chemical Properties
space
General Information
Form
liquid
space
Color
colorless, clear
space
Odor
not significant
space
Important health, safety and environmental information
55.4 掳F (13 掳C) estimated
Flash Point
space
685.4 掳F (363 掳C) estimated
Auto Ignition
space
Flammable IB
Flammability Class
space
173.3 掳F (78.5 掳C) estimated
Boiling Point
space
-173.4 掳F (-114.1 掳C) estimated
Melting Point
space
53.5157 hPa estimated
Vapor Pressure
space
91.98 % estimated
Volatile Organic
space
Other information
Not available
.
10. Chemical Stability & Reactivity Information
space
Stability
Stable
space
Hazardous decomposition products
carbon oxides, nitrogen oxides (NOx)
space
Conditions to avoid
Heat, flames and sparks.
space
Incompatibility
strong oxidizing agents
space
Hazardous Polymerization
Will not occur.
Material ID 4909 Material Name EPIBATIDINE [125I]-
3/ 6
MSDS US
.
11. Toxicological Information
space
Acute Toxicity
May be harmful by inhalation, ingestion, skin adsorption.
Severe eye irritation
Irritating to respiratory system and skin.
NIOSH - Selected LD50s and LC50s
ACETONITRILE 75-05-8 Inhalation LC50 Rat: 7551 ppm/8H; Inhalation LC50
Mouse: 2693 ppm/1H; Oral LD50 Rat: 2460 mg/kg;
Oral LD50 Mouse: 269 mg/kg; Dermal LD50 Rabbit:
1250 L/kg
ETHANOL 64-17-5 Inhalation LC50 Rat: 20000 mg/kg/10H; Inhalation
LC50 Mouse: 39 g/m3/4H; Oral LD50 Rat: 7060
mg/kg; Oral LD50 Mouse: 3450 mg/kg
space
Carcinogenicity Data
ACETONITRILE
Ingredient(s)
- ACGIH Not Classified Carcinogen
ETHANOL
- ACGIH Not Classified Carcinogen
space
Symptoms and Target Organs
NIOSH - Pocket Guide - Target Organs
ACETONITRILE 75-05-8 kidneys, liver, CVS, CNS, respiratory system
ETHANOL 64-17-5 respiratory system, skin, eyes, CNS, liver, blood,
reproductive system
space
.
12. Ecological Information
space
Ecotoxicity
Not available
Ecotoxicity - Freshwater Fish Species Data
ACETONITRILE 75-05-8 96 Hr LC50 fathead minnow: 1640 mg/L
(flow-through)
ETHANOL 64-17-5 96 Hr LC50 rainbow trout (30 days old):12900 mg/L
(flow-through);24 Hr LC50 fingerling trout: 11200
mg/L;96 Hr LC50 fathead minnow: 14200 mg/L
(flow-through)
Ecotoxicity - Microtox Data
ETHANOL 64-17-5 5 min EC50 Photobacterium phosphoreum: 35470
mg/L; 30 min EC50 Photobacterium phosphoreum:
34634 mg/L
space
Mobility
Not available
space
Persistence and degradability
Not available
space
Bioaccumulative potential
Not available
space
Other adverse effects
Not available
Material ID 4909 Material Name EPIBATIDINE [125I]-
4/ 6
MSDS US
.
13. Disposal Considerations
space
Disposal Instructions
In accordance with local and national regulations.
space
Waste from residues / unused products
Dispose of in accordance with local regulations
space
.
14. Transportation Information
space
US DOT
space
Other Information
Please refer to documentation sent with product for transport information
space
.
15. Regulatory Information
space
CERCLA/SARA Section 313
ACETONITRILE
Ingredient(s)
space
US Federal Regulations
CERCLA/SARA - Hazardous Substances and their Reportable Quantities
ACETONITRILE 75-05-8 5000 lb final RQ; 2270 kg final RQ
CERCLA/SARA - Section 313 - Emission Reporting
ACETONITRILE 75-05-8 1.0 % de minimis concentration
TSCA (Toxic Substances Control Act) - Section 12(b) - Export Notification
ACETONITRILE 75-05-8 Section 4
space
State Regulations
California - Proposition 65 - Developmental Toxicity
ETHANOL 64-17-5 developmental toxicity, initial date 10/1/87 (when in
alcoholic beverages)
Massachusetts - Right To Know List
ACETONITRILE 75-05-8 Present
ETHANOL 64-17-5 Teratogen
Massachusetts - Toxics Use Reduction Act
ACETONITRILE 75-05-8 CERCLA and 313 chemical
New Jersey - Right to Know Hazardous Substance List
ACETONITRILE 75-05-8 sn 0008
ETHANOL 64-17-5 sn 0844
Pennsylvania - RTK (Right to Know) List
ACETONITRILE 75-05-8 Environmental hazard
ETHANOL 64-17-5 Present
Rhode Island - Hazardous Substance List
ACETONITRILE 75-05-8 Toxic; Flammable
ETHANOL 64-17-5 Toxic; Flammable
space
International Regulations
Canada - WHMIS - Ingredient Disclosure List
ACETONITRILE 75-05-8 0.1 % (English Item 12, French Item 43)
ETHANOL 64-17-5 0.1 % (English Item 684, French Item 805)
.
16. Other Information
space
Recommended use
For research use only.
Material ID 4909 Material Name EPIBATIDINE [125I]-
5/ 6
MSDS US
space
Disclaimer
The information provided in this Material Safety Data Sheet is based on our present knowledge,
and believed to be correct at the date of publication. However, no representation is made
concerning its accuracy and completeness. It is intended as guidance only, and is not to be
considered a warranty or quality specification. All materials may present unknown hazards, and
should be used with caution. Although certain hazards are described, we cannot guarantee that
these are the only hazards which exist. PerkinElmer Life and Analytical Sciences shall not be held
liable for any damage resulting from handling or from contact with the product.
space
Chemical Product and Company Identification: Product Use
MSDS Sections Updated
Hazards Identification: Emergency Overview
Accidental Release Measures: Evacuation Procedures
Accidental Release Measures: Environmental precautions
Handling and Storage: Storage
Handling and Storage: Specific Use(s)
Physical & Chemical Properties: Odour
Physical & Chemical Properties: Other information
Chemical Stability & Reactivity Information: Hazardous decomposition
products
Ecological Information: Ecological Information
Ecological Information: Other adverse effects
Ecological Information: Persistence and degradability
Ecological Information: Bioaccumulative potential
Ecological Information: Ecotoxicity
Transportation Information: Other Information
space
Material ID 4909 Material Name EPIBATIDINE [125I]-
6/ 6
MSDS US
|