Creation Date: 12-15-2004
Revision Date: 10-06-2005
Material Safety Data Sheet
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1. Chemical Product and Company Identification
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Material Name A-85380, [125I]-
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01
Version #
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NEX413000MC
Item #
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Laboratory Reagent
Product Use
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PerkinElmer Life and Analytical Sciences
Identification Of The
710 Bridgeport Avenue
Company/Undertaking
Shelton, CT 06484
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Technical Support 800-762-4000
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CHEMTREC 800-424-9300
Emergency Telephone
Emergency Phone 800-762-4000
Number
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2. Composition / Information on Ingredients
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Hazardous component(s) CAS # Percent PEL TLV
ETHANOL 64-17-5 80 - 90 1000 ppm 1000
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ACETONITRILE 75-05-8 1 - 2.5 40 ppm 20
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Non-hazardous component(s) CAS # Percent
WATER 7732-18-5 2.5 - 10
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A-85380, [125I]- < 0.01
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Other components below reportable levels 0.0001 - 0.01
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3. Hazards Identification
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Emergency Overview
Highly flammable.
Severe eye irritation
Irritating to respiratory system and skin.
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4. First Aid Measures
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General advice
In case of feeling unwell: Call a physician immediately.
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First Aid
Skin contact
Wash off immediately with plenty of water for at least 15 minutes.
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Eye contact
Rinse immediately with plenty of water for at least 15 minutes. If eye irritation persists, consult a
specialist.
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Inhalation
Move to fresh air. Oxygen or artificial respiration if needed.
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Ingestion
Clean mouth with water and drink afterwards plenty of water. Never give anything by mouth to
an unconscious person.
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5. Fire Fighting Measures
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Suitable extinguishing media
use dry chemical, CO2, water spray or "alcohol" foam
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Special protective equipment for firefighters
Wear suitable protective equipment
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Unusual Fire & Explosion Hazards
In the event of fire toxic fumes may be formed.
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6. Accidental Release Measures
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Evacuation Procedures
Isolate area. Keep unnecessary personnel away.
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Personal precautions
Remove all sources of ignition. Ensure adequate ventilation. Use personal protective equipment.
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Environmental precautions
Do not flush into surface water or sanitary sewer system.
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Methods for cleaning up
Soak up with inert absorbent material. Clean contaminated surface thoroughly. Keep in suitable and
closed containers for disposal.
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7. Handling and Storage
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Handling
Use only in area provided with appropriate exhaust ventilation. Wear personal protective
equipment. Do not breathe vapours or spray mist. Avoid contact with skin and eyes. Keep away
from heat and sources of ignition.
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Storage
Keep away from heat, sparks, and flame. Keep tightly closed in a dry, cool and well-ventilated
place.
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8. Exposure Controls / Personal Protection
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Exposure Limit Values
ACGIH - Threshold Limits Values - Time Weighted Averages (TLV-TWA)
ACETONITRILE 75-05-8 20 ppm TWA
ETHANOL 64-17-5 1000 ppm TWA
OSHA - Final PELs - Time Weighted Averages (TWAs)
ACETONITRILE 75-05-8 40 ppm TWA; 70 mg/m3 TWA
ETHANOL 64-17-5 1000 ppm TWA; 1900 mg/m3 TWA
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Exposure Controls
Engineering measures to reduce exposure
Provide adequate ventilation.
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Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin,
eyes and clothing. Keep away from food and drink. Wash hands before breaks and immediately
after handling the product.
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Respiratory protection
Do not inhale aerosol. No personal respiratory protective equipment normally required.
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Hand protection
solvent-resistant gloves
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Eye protection
safety glasses with side-shields
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Skin and body protection
Lab coat.
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9. Physical & Chemical Properties
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General Information
Form
Liquid.
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Color
colorless, clear
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Odor
none
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Important health, safety and environmental information
55.4 掳F (13 掳C) estimated
Flash Point
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685.4 掳F (363 掳C) estimated
Auto Ignition
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Flammable IB
Flammability Class
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173.3 掳F (78.5 掳C) estimated
Boiling Point
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-173.4 掳F (-114.1 掳C) estimated
Melting Point
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3
pH
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53.5157 hPa estimated
Vapor Pressure
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91.98 % estimated
Volatile Organic
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10. Chemical Stability & Reactivity Information
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Stability
Stable
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Hazardous decomposition products
carbon oxides, nitrogen oxides (NOx)
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Conditions to avoid
Heat, flames and sparks.
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Incompatibility
strong oxidizing agents
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Hazardous Polymerization
Will not occur.
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11. Toxicological Information
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Acute Toxicity
May be harmful by inhalation, ingestion, skin adsorption.
Eye contact: Cause severe irritation, lachrymation.
Irritating to respiratory system and skin.
NIOSH - Selected LD50s and LC50s
ACETONITRILE 75-05-8 Inhalation LC50 Rat: 7551 ppm/8H; Inhalation LC50
Mouse: 2693 ppm/1H; Oral LD50 Rat: 2460 mg/kg;
Oral LD50 Mouse: 269 mg/kg; Dermal LD50 Rabbit:
1250 L/kg
ETHANOL 64-17-5 Inhalation LC50 Rat: 20000 mg/kg/10H; Inhalation
LC50 Mouse: 39 g/m3/4H; Oral LD50 Rat: 7060
mg/kg; Oral LD50 Mouse: 3450 mg/kg
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Carcinogenicity Data
ACETONITRILE
Ingredient(s)
- ACGIH Not Classified Carcinogen
ETHANOL
- ACGIH Not Classified Carcinogen
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Symptoms and Target Organs
NIOSH - Pocket Guide - Target Organs
ACETONITRILE 75-05-8 kidneys, liver, CVS, CNS, respiratory system
ETHANOL 64-17-5 respiratory system, skin, eyes, CNS, liver, blood,
reproductive system
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12. Ecological Information
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Ecotoxicity
Ecotoxicity - Freshwater Fish Species Data
ACETONITRILE 75-05-8 96 Hr LC50 fathead minnow: 1640 mg/L
(flow-through)
ETHANOL 64-17-5 96 Hr LC50 rainbow trout (30 days old):12900 mg/L
(flow-through);24 Hr LC50 fingerling trout: 11200
mg/L;96 Hr LC50 fathead minnow: 14200 mg/L
(flow-through)
Ecotoxicity - Microtox Data
ETHANOL 64-17-5 5 min EC50 Photobacterium phosphoreum: 35470
mg/L; 30 min EC50 Photobacterium phosphoreum:
34634 mg/L
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Mobility
Not available
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Persistence and degradability
Not available
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Bioaccumulative potential
Not available
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Other adverse effects
Not available
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13. Disposal Considerations
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Disposal Instructions
In accordance with local and national regulations.
Material ID 14565 Material Name A-85380, [125I]-
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Waste from residues / unused products
In accordance with local and national regulations.
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14. Transportation Information
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US DOT
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Other Information
Please refer to documentation sent with product for transport information
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15. Regulatory Information
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CERCLA/SARA Section 313
A-85380, [125I]-
Material
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ACETONITRILE
Ingredient(s)
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US Federal Regulations
CERCLA/SARA - Hazardous Substances and their Reportable Quantities
ACETONITRILE 75-05-8 5000 lb final RQ; 2270 kg final RQ
CERCLA/SARA - Section 313 - Emission Reporting
ACETONITRILE 75-05-8 1.0 % de minimis concentration
TSCA (Toxic Substances Control Act) - Section 12(b) - Export Notification
ACETONITRILE 75-05-8 Section 4
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State Regulations
California - Proposition 65 - Developmental Toxicity
ETHANOL 64-17-5 developmental toxicity, initial date 10/1/87 (when in
alcoholic beverages)
Massachusetts - Right To Know List
ACETONITRILE 75-05-8 Present
ETHANOL 64-17-5 Teratogen
Massachusetts - Toxics Use Reduction Act
ACETONITRILE 75-05-8 CERCLA and 313 chemical
New Jersey - Right to Know Hazardous Substance List
ACETONITRILE 75-05-8 sn 0008
ETHANOL 64-17-5 sn 0844
Pennsylvania - RTK (Right to Know) List
ACETONITRILE 75-05-8 Environmental hazard
ETHANOL 64-17-5 Present
Rhode Island - Hazardous Substance List
ACETONITRILE 75-05-8 Toxic; Flammable
ETHANOL 64-17-5 Toxic; Flammable
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International Regulations
Canada - WHMIS - Ingredient Disclosure List
ACETONITRILE 75-05-8 0.1 % (English Item 12, French Item 43)
ETHANOL 64-17-5 0.1 % (English Item 684, French Item 805)
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16. Other Information
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Recommended use
For research use only.
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Disclaimer
The information provided in this Material Safety Data Sheet is based on our present knowledge,
and believed to be correct at the date of publication. However, no representation is made
concerning its accuracy and completeness. It is intended as guidance only, and is not to be
considered a warranty or quality specification. All materials may present unknown hazards, and
should be used with caution. Although certain hazards are described, we cannot guarantee that
these are the only hazards which exist. PerkinElmer Life and Analytical Sciences shall not be held
liable for any damage resulting from handling or from contact with the product.
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Material ID 14565 Material Name A-85380, [125I]-
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