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MSDS Material Safety Data Sheet
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File Name: roche-applied-science_com---799050.asp
                                        Material Safety Data Sheet
Authorization date: 08/06/1999
Revision date: 08/22/2006
Print Date: 08/24/2006
Version: 0


1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING

Product name: BM CYCLINE
Product number: 799050
Global material number: 10799050001
Business area: Roche Applied Sciences
Product line: Not applicable
Instrument type: Not applicable
Supplier: Emergency telephone number:
Roche Diagnostics Corporation CHEMTREC:
9115 Hague Road 1-800-424-9300 (U.S. or Canada)
Indianapolis, IN 46250 1-703-527-3887 (International)
Site Phone Number: 1-800-428-5074


2. COMPOSITION/INFORMATION ON INGREDIENTS

Description 1: Bottle 1
Components CAS Number Weight % OSHA PEL: OSHA STEL: ACGIH TLV: ACGIH STEL:
BM CYCLINE NONE 95-100 NA NA NA NA



3. HAZARDS IDENTIFICATION

Emergency Overview

NFPA Ratings: Health= 1 Flammability= 0 Reactivity= 0 Special= T
Special Definitions: A=Allergen CA=Carcinogen CO=Corrosive F=Flammable H=Harmful I=Irritant Ox=Oxidizer PB=Potential Biohazard
R=Reproductive S=Sensitizer T=Toxic T+=Highly Toxic W=Water Reactive

Principle routes of exposure: Ingestion, skin and/or eye contact.

Inhalation: None.

Ingestion: Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhea.

Skin contact: None.

Eye contact: May cause irritation.

Sensitization or Odor threshold: None.

Medical conditions aggravated by None known
exposure:

Additional information: None

4. FIRST AID MEASURES

Inhalation: Consult a physician. Move to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen.

Skin contact: Wash off immediately with plenty of water for at least 15 minutes. If skin irritation persists, call a physician.

Ingestion: Call a physician immediately. Do not induce vomiting without medical advice.

Eye contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.

Notes to physician: None determined

5. FIRE-FIGHTING MEASURES

Suitable extinguishing media: Use dry chemical, CO2, water spray or "alcohol" foam.
Unusual hazards: None known.

Special protective equipment for In the event of fire, wear self-contained breathing apparatus.
firefighters:

6. ACCIDENTAL RELEASE MEASURES

Personal precautions: Use personal protective equipment. Evacuate personnel to safe areas. Remove all sources of ignition.
Avoid dust formation. Ensure adequate ventilation.
Environmental precautions: Prevent further leakage or spillage if safe to do so. Prevent product from entering drains. Do not flush into
surface water or sanitary sewer system. Do not let product enter drains.
Methods for cleaning up: Never return spills in original containers for re-use. Soak up with oil absorbent material. Sweep up or
vacuum (if powder) or soak up with inert absorbent material (if liquid), then place into a suitable clean, dry,
closed container, and label for disposal.

7. HANDLING AND STORAGE

Handling: Protect from contamination. Wear personal protective equipment.
Storage: Keep containers dry and tightly closed to avoid moisture absorption and contamination.

8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering measures: Not applicable.

Personal Protective Equipment

Respiratory protection: Respiratory protection is not required under normal use of this product. If respiratory protection is needed,
follow the OSHA regulation, 29CFR1910.134. Always use a NIOSH approved respirator when necessary.

Hand protection: Wear appropriate protective gloves to prevent skin contact. Replace torn or punctured gloves promptly.

Skin and body protection: Wear appropriate body protection to prevent skin contact.

Eye protection: Wear appropriate eye protection to prevent eye contact.

Hygiene measures: When using, do not eat, drink or smoke. Keep away from food and drink. Keep away from tobacco
products. Wash hands before breaks and immediately after handling the product. Handle in accordance
with good industrial hygiene and safety practice for diagnostics.

9. PHYSICAL AND CHEMICAL PROPERTIES

Boiling point/range: No information available
Melting point/range: Not determined
pH: Not determined
Physical state: Not determined.
Flash point: No information available.
LEL (%): Not determined
UEL (%): Not determined

10. STABILITY AND REACTIVITY

Stability: Stable under recommended storage conditions.
Polymerization: None under normal processing.
Hazardous decomposition products: None reasonably foreseeable.
Materials to avoid: No data available.

11. TOXICOLOGICAL INFORMATION

Description 1: Bottle 1
Inhalation: No additional data available
Skin: No additional data available
Oral: No additional data available
Mutagenic effects: No data is available on the product itself
Reproductive toxicity: No data is available on the product itself
Carcinogenic effects:



Product number: 799050 Page 2 of 3
Product name: BM CYCLINE
12. ECOLOGICAL INFORMATION

Bioaccumulation: No data available

Aquatic toxicity: Not applicable

Ecotoxicity effects: No data is available on the product itself


13. DISPOSAL CONSIDERATIONS

Waste from residues / unused products: Waste disposal must be in accordance with appropriate Federal, State, and local regulations. This product,
if unaltered by use, may be disposed of by treatment at a permitted facility or as advised by your local
hazardous waste regulatory authority. Residue from fires extinguished with this material may be
hazardous.

14. TRANSPORT INFORMATION

Is product hazardous to ship? No
DOT

Proper shipping name: None
UN Number: Not applicable Hazard class: Not applicable Subsidiary risk: Not applicable Packing group: Not applicable

ICAO/IATA

Proper shipping name: None
UN Number: Not applicable Hazard class: Not applicable Subsidiary risk: Not applicable Packing group: Not applicable


15. REGULATORY INFORMATION

U.S. Regulations:

U.S. CERCLA/SARA/TSCA Regulatory Information: The following chemicals are listed under the following TSCA/SARA/CERCLA lists. Refer to
TSCA regulation if you need a definition for acronyms that may be shown in the TSCA Inventory field in the table below


U.S. Clean Water Act (CWA)/ California The following chemicals are listed under the CWA and/or California Proposition 65:
Proposition 65:


Canadian Regulations:

Canada DSL Inventory List - This product does not comply with DSL
Canada NDSL Inventory List - This product does not comply with NDSL


16. OTHER INFORMATION

Reason for revision: Not applicable
References: None.
Additional advice: None
Prepared by: Roche Diagnostics, Health & Safety Department, MSDS Contact: 317-521-7425 or 317-521-7505

The information, data and recommendations contained herein are based upon information believed by Roche Diagnostics Corporation, after reasonable investigation and
research, to be accurate; however, Roche Diagnostics Corporation does not warrant the accuracy of this information. All materials and mixtures may present unknown
hazards and should be used with caution. When necessary or appropriate, independent opinions regarding the risk of handling or exposure should be obtained from trained
professionals. Roche Diagnostics Corporation disclaims any warranty against patent infringement and the implied warranties of merchantability and fitness for a particular
purpose. Customer's sole and exclusive remedy shall be replacement of the product or return of the product and refund of the purchase price, at Roche Diagnostics
Corporation's option. In no case shall Roche Diagnostics Corporation be liable for incidental or consequential damages, including lost profits.

End of Safety Data Sheet




Product number: 799050 Page 3 of 3
Product name: BM CYCLINE

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