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MSDS Material Safety Data Sheet
CAS

7631-86-9

File Name: isco_com---redisep-silica-msds.asp
                         MATERIAL SAFETY DATA SHEET


1. PRODUCT AND COMPANY IDENTIFICATION

Preparation/Revision Date:
03/19/07

Phone Number: (402) 464-0231
Distributor:
Teledyne Isco, Inc.
P.O. Box 82531 Hours: Mon.-Fri. 8:00a.m.-4:30p.m. CST
Lincoln, NE 68501-2531

Product Name: RediSep庐 - Normal Phase, Reverse Phase C-18,
Amine, Cyano, Diol, SAX, SCX

Solid Sample Cartridges 鈥? 5g, 25g, 65g, 270g

Silica Gel

Product Content: Amorphous Silicon Dioxide
or
Derivatized Amorphous Silicon Dioxide


2. COMPOSITION / INFORMATION ON INGREDIENTS

Component: Amorphous Silicon Dioxide, chemically prepared CAS #: 7631-86-9

Additional Information: See section 8 for exposure limits.


3. HAZARDS IDENTIFICATION

NFPA ratings (scale 0 鈥? 4) HIMS 鈥? ratings (scale 0 鈥? 4)

Health = 1 Health 1
Fire = 0 Fire 0
Reactivity = 0 Reactivity 0



The statements contained herein are offered for informational purposes only and are
based upon technical data that Teledyne Isco, Inc. believes to be accurate. It is intended
for use only by persons having the necessary technical skill and at their own discretion
and risk. Since conditions and manner of use are outside our control, we make NO
WARRANTY, EXPRESS OR IMPLIED, OR MERCHANTABILITY, FITNESS OR
OTHERWISE.


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4. FIRST AID MEASURES

Emergency First Aid:
GET MEDICAL ASSISTANCE IF ANY ADVERSE EFFECTS SHOULD DEVELOP.

Skin: Immediately rinse with water. Generally the product does not irritate the skin.

Eyes: Immediately rinse under running water for at least 15 minutes, lifting upper and
lower eyelids occasionally.
Inhalation: Supply fresh air.

Ingestion: If large amounts are swallowed, wash mouth out with water.


5. FIRE FIGHTING MEASURES

Suitable extinguishing agents:
CO2, extinguishing powder or water spray. Fight larger fire with alcohol resistant foam.

Fire Fighting Procedures: Use fire fighting measures that suit the environment.

Protective equipment: Wear protective equipment.

Fire & Explosion Hazards: Not an explosion hazard

Flammability: Not flammable

Flash Point (潞F): Not applicable

Auto Igniting: Not self igniting

Additional Information:
Dispose of fire debris and contaminated water in accordance with official regulations.


6. ACCIDENTAL RELEASE MEASURES

Person-related safety precautions: Avoid formation of dust. Wear protective clothing.

Measures for cleaning/collecting: Vacuuming or wet sweeping may be used to avoid
dust dispersal.

Measures for environmental protection: Containerize for reclamation or disposal.

Additional information: See section 7 for safe handling.
See section 8 for information on personal protection equipment.
See section 13 for disposal information.

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7. HANDLING AND STORAGE

Handling:
Information for safe handling: Prevent formation of dust.

Information about protection against explosions and fires:
The product is not flammable. When pouring into a container of flammable liquid,
ground both containers electrically to prevent a static electric spark.

Storage:
Information about storage conditions: Keep container tightly sealed.

Information about storage in one common storage facility: None required.

Class according to regulation on flammable liquids: None Applicable


8. EXPOSURE CONTROLS / PERSONAL PROTECTION

Component: Amorphous Silicon Dioxide, chemically prepared CAS #: 7631-86-9

Exposure Limits: NIOSH short term value 鈥? IDLH: 3000mg/m3
OSHA TWA 鈥? PEL: 80/(%SiO2) mg/m3
NIOSH TWA 鈥? REL: 6mg/m3
ACGIH TWA 鈥? TLV: 10mg/m3 Total Dust
5mg/m3 Respirable fraction

Personal Protective Equipment:
General protection and hygienic measures:
The usual precautionary measures for handling chemicals should be followed.

Breathing equipment:
If exposure limit is exceeded, a suitable respiratory protective device is
recommended.


Eye protection: Safety glasses.


Protection of hands: The glove material has to be impermeable to the product/
the substance/ the preparation.


Body protection: Protective work clothing.




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9. PHYSICAL AND CHEMCIAL PROPERTIES

Physical State: RediSep庐 - Solid, (50mm Average particle size) powder
Solid Sample Cartridge 5g, 25g 鈥? Solid, 40-63渭m powder
Solid Sample Cartridge 65g, 270g 鈥? Solid, 75-150渭m powder

Color: White to off-white
Odor: None Density: Not determined
Bulk Density (lb/ft3): 25-35
pH at 20潞C (68潞F): 6.0-8.0 (5% slurry)
Melting Point (潞C): Undetermined Solubility in Water (%): Insoluble


10. STABILITY AND REACTIVITY

Thermal decomposition/conditions to be avoided:
No decomposition if used according to specifications.

Dangerous Reactions: Reacts with Hydrogen Fluoride.

Dangerous products of decomposition: No dangerous decomposition products known.


11. TOXICOLOGICAL INFORMATION

Component: Amorphous Silicon Dioxide, chemically prepared CAS #: 7631-86-9

Oral 鈥? LD50: 10000 mg/kg (rat)
Acute toxicity:
Dermal 鈥? LD50: >5000 mg/kg (rabbit) OECD 402
Inhalative 鈥? LC50: >0.139 mg/l/14h (rat)

Primary irritant effect:

On the skin: May cause irritation with dryness and abrasion.

In the eye: May cause abrasion, redness and pain.

Sensitization: No sensitizing effects known.

Subacute to chronic toxicity:
Amorphous silicon dioxide, chemically prepared:
No negative effects were determined during tests for chronic oral toxicity,
carcinogenicity, teratogenicity and fertility. No irreversible changes and no symptoms of
silicosis were determined during tests for chronic inhalative toxicity.

Additional toxicological information:
When used and handled according to specifications, the product does not have any
harmful effects based on the experience and information provided to us by the
manufacturer.
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12. ECOLOGY INFORMATION

Component: Amorphous Silicon Dioxide, chemically prepared CAS #: 7631-86-9

Aquatic toxicity: Fish 鈥? LC50 (96 h): >10000 mg/l (Brachydanio rerio) OECD 202
Water Flea 鈥? EC50 (24 h): >1000 mg/l (Daphnia magna) OECD 202

General Note: Generally not hazardous for water.


13. DISPOSAL CONSIDERATIONS

EPA Waste Numbers: None

Dispose of in accordance with all federal, state, provincial and local regulations.


14. TRANSPORT INFORMATION

Not regulated as hazardous goods by DOT, ADR, IMO or IATA.


15. REGULATORY INFORMATION

None of the ingredients are listed under the following:
SARA section 313 and 355 TLV-ACGIH
Proposition 65 NIOSH-Ca
EPA OSHA-Ca
IARC Canadian NDSL
NTP

All ingredients are listed with the following:
TSCA
MAK
Canadian DSL
Japan ENCS
Korea ECL
Philippines: PICCS
Australia: AICS
European EINECS




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16. OTHER INFORMATION

The statements contained herein are offered for informational purposes only and are based upon technical
data that Teledyne Isco, Inc. believes to be accurate. It is intended for use only by persons having the
necessary technical skill and at their own discretion and risk. Since conditions and manner of use are
outside our control, we make NO WARRANTY, EXPRESS OR IMPLIED, OR MERCHANTABILITY,
FITNESS OR OTHERWISE.




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