Material Safety Data Sheet
Effective Date: Oct. 16, 2006
Weber Scientific Telephone for information: 609-584-7677
2732 Kuser Road Emergency Telephone :Chem-Tel: 800-255-3924
Hamilton, NJ 08691 Outside USA: 813-248-0585
Section 1. Product Identification
Product name: Buffer Substrate Tablet: Phos-Phax tablet
General Use: alkaline phosphatase test reagent
Product description: white tablet
Product code: 4058-00, 4058-10
Section 2. Composition/Information on Ingredients
SARA
Hazardous components CAS # % by weight OSHA PEL MSHA TWA Title III
Sodium Chloride 7647-14-5 45-60 n/a n/a no
(NaCl) (a)
15 mg/m3 10 mg/m3
Sodium Sesquicarbonate 533-96-0 30-50 yes
Dihydrate (a,b) (total dust) (total dust)
(Na2 CO3 鈥? NaHCO2 鈥? 2H2 O )
Phenyl Phosphate Disodium 3279-54-7 6-10 n/a n/a no
(C6 H5 PO4 Na2)
(a,) See Section 15
(b) Refer to Section 13 鈥淒isposal Considerations鈥? for Resource Conversation and Recovery Act (RCRA) status in 40 CFR 260-281.
.
Section 3. Hazards Identification
Emergency Overview:
Product is non-combustible and can react with acids or oxidizers to release carbon dioxide gas and heat
Potential Health Effects:
In the tablet form this product has minimal potential health effects. Direct contact with the powdered
product causes irritation of the eyes and skin. Internal toxicity is low.
INHALATION: Excessive levels of airborne dust may irritate the mucous membranes and the upper
respiratory tract.
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SKIN: Continuous contact with the powdered product may cause red, dry, cracked skin..
EYES: Direct contact with the powdered product causes irritation of the eyes .
Section 4- First Aid Measures
INHALATION: Remove affected person to fresh air,. If breathing is difficult or discomfort occurs obtain
medical attention.
SKIN: Wash affected area with soap and water, launder contaminated clothing before reuse, if irritation
persists seek medical attention.
EYES: Remove contact lenses, flush eyes with clear running water for 15 minutes while holding eyelids
open, if irritation persists seek medical attention.
INGESTION: Drink plenty of water. Never give anything by mouth to an unconscious person. If any
discomfort persists obtain medical attention.. DO NOT induce vomiting.
Section 5- Fire Fighting Measures
FLASH POINT : not applicable
FLAMMABLE LIMITS: not applicable. Phenyl Phosphate Disodium may be combustible at high
temperature
AUTOIGNITION TEMPERATURE: not applicable
EXTINGUISHING MEDIA: Carbon dioxide, water, water fog, dry chemical.
FIRE FIGHTING PROCEDURES: none.
UNUSUAL FIRE AND EXPLOSION HAZARDS: none.
HAZARDOUS COMBUSTION PRODUCTS: fumes of sodium oxide, carbon oxides and phosphates.
Section 6- Environmental Release Measures
Prevent large quantities of this product from contacting vegetation or waterways; large spills could kill
vegetation or fish. If spilled, vacuum or sweep-up the material. Federal regulations do not require
notification for spills of this product. State and local regulations may contain different requirements;
consult local authorities.
Section 7- Handling and Storage
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE: Avoid breathing concentrated dust
and wear dust mask as required to prevent contact with eyes. Protect from excessive heat and moisture,
store away from acids and strong oxidizing agents. Keep containers closed. May be hygroscopic.
Section 8- Exposure Controls/Personal Protection
ENGINEERING CONTROLS: no specific measures required for this tableted product.
PERSONAL PROTECTION:
Federal guidelines treat the ingredients in this product, in their powdered forms as a nuisance dust with no
product-specific guidelines.
RESPIRATORY PROTECTION: Whenever dust in the worker鈥檚 breathing zone can not be controlled
with ventilation the workers should wear respirators or dust masks approved by NIOSH or comparable
certification organizations to protect from airborne dust.
OTHER PROTECTIVE CLOTHING OR EQUIPMENT: This tableted product is generally non-
irritating to intact skin. Skin irritation may occur where skin has been damaged. In this situation minimize
skin contact by wearing gloves.
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Section 9- Physical and Chemical Properties
BOILING POINT: n/a VAPOR PRESSURE @ 68掳F: n/a
VAPOR DENSITY: (air = 1): n/a SOLUBILITY IN WATER: soluble
VISCOSITY: n/a EVAPORATION RATE (n-butyl acetate =1): n/a
FREEZING POINT: n/a PHYSICAL STATE: solid tablet
VOLATILE ORGANIC CMPDS (total VOCs): none for inorganic materials.
Section 10- Stability and Reactivity
STABILITY: Stable CONDITIONS TO AVOID: contact with acids , strong oxidizers and
moisture due to hygroscopic nature of the Phenyl Phosphate Disodium.
INCOMPATABILITY (materials to avoid): aluminum powder, strong acids, strong oxidizers and
fluorine.
HAZARDOUS DECOMPOSITION OR BYPRODUCTS: carbon and phosphorus oxides .
HAZARDOUS POLYMERIZATION: will not occur
Section 11- Toxicological Information
Hazardous components CAS # % by weight LD50 LCD50
Species species
>42,000 mg/m3
Sodium Chloride 3000 mg/kg
7647-14-5 45-60
oral-rat inhalation-rat
(NaCl) (a)
Sodium Sequicarbonate 533-96-0 30-50
Dihydrate >2000 mg/kg > 5.03mg /4 hr
(Na2 CO3 鈥? NaHCO2 鈥? 2H2 O ) oral-rat inhalation-rat
Phenyl Phosphate Disodium 3279-54-7 6-10 n/a n/a
(C6 H5 PO4 Na2)
Section 12- Ecological Information
No data are available on the adverse effects of this material on the environment. Not listed as a hazardous
pollutant (40 CFR 116) nor as a toxic pollutant (40 CFR 401.15) in the Clean Water Act (CWA) Section
307/311. Based on the chemical composition of this product it is assumed that it can be treated in an
acclimatized biological waste treatment plant system in limited quantities. However, such treatment
should be evaluated and approved for each specific biological system.
Section 13- Disposal Considerations
WASTE DISPOSAL METHOD: Dispose of in accordance to Local, State and Federal Regulations. This
product is not listed as a hazardous waste according to US Federal RCRA regulations. Refer to 鈥?40 CFR
Protection of the Environment Parts 260-299鈥?.
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Section 14- Transport Information
PROPER SHIPPING NAME: none
HAZARD CLASS / pack group: n/a
IDENTIFICATION NUMBER: none LABEL: n/a
IATA HAZARD CLASS/ pack group: not regulated
IMDG HAZARD CLASS: not regulated
Canadian TDG Class/Division: n/a
HAZARD SYMBOLS: n/a
Note: Transportation information provided is for reference only.
Section 15- Regulatory Information
TSCA (Toxic Substance Control Act)
Components of this product are listed on the TSCA Inventory
SARA Title III (Superfund Amendments and Reauthorization Act)
Section 302: not listed
Section311/312 Hazard Categories : immediate acute health hazard
Section 313 Reportable Ingredients: none
CERCLA (Comprehensive Response Compensation and Liability Act): not listed as a hazardous
substance
California Proposition 65: not listed
WHMIS Canadian Workplace hazardous materials information system: hazard classification: n/a,
IDL (Canadian Ingredient Disclosure List)
Components of this product listed on the Canadian Ingredient Disclosure List are shown in Section 2.
EINECS (European Inventory of Existing Commercial Chemical Substances)
Components of this product are on the European Inventory of Existing Commercial Chemical Substances
EC Risk Phrases EC Safety Phrases
None none
Section 16- Other Information
No Specific notes
HMIS HAZARD RATINGS health: slight
Flammability: minimal
Reactivity: minimal
PERSONAL PROTECTIVE EQUIPMENT: B: safety glasses and gloves.
REVISION SUMMARY: none
MSDS prepared by: John R Beck, PhD
Technical Service and Quality Control Manager
Weber Scientific
The information contained herein is believed to be accurate but is not warranted to be so. Users are advised to confirm
in advance of need that the information is current, applicable, and suited to the circumstances of use. Weber Scientific
assumes no responsibility for injury to vendee or third persons proximately caused by the material if reasonable safety
procedures are not adhered to as stipulated in the data sheet. Furthermore, Weber Scientific assumes no responsibility
for injury caused by abnormal use of this product even if reasonable safety procedures are followed.
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