MSDS Number: X2000 * * * * * Effective Date: 02/16/06 * * * * * Supercedes:
04/01/03
XYLENES
1. Product Identification
Synonyms: Dimethyl benzene, xylol, methyltoluene
CAS No.: 1330-20-7
Molecular Weight: 106.17
Chemical Formula: C6H4(CH3)2
Product Codes:
J.T. Baker: 5377, 5813, 9483, 9489, 9490, 9493, 9494, 9499, 9516, X516
Mallinckrodt: 8664, 8668, 8671, 8672, 8802, V052
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------------ ---------
m-Xylene 108-38-3 40 - 65% Yes
o-Xylene 95-47-6 15 - 20% Yes
p-Xylene 106-42-3 < 20% Yes
Ethyl Benzene 100-41-4 15 - 25% Yes
3. Hazards Identification
Emergency Overview
--------------------------
DANGER! HARMFUL OR FATAL IF SWALLOWED. VAPOR
HARMFUL. AFFECTS CENTRAL NERVOUS SYSTEM. CAUSES
SEVERE EYE IRRITATION. CAUSES IRRITATION TO SKIN
AND RESPIRATORY TRACT. MAY BE HARMFUL IF
ABSORBED THROUGH SKIN. CHRONIC EXPOSURE CAN
CAUSE ADVERSE LIVER, KIDNEY, AND BLOOD EFFECTS.
FLAMMABLE LIQUID AND VAPOR.
SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 2 - Moderate (Life)
Flammability Rating: 2 - Moderate
Reactivity Rating: 1 - Slight
Contact Rating: 3 - Severe
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER
GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
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Potential Health Effects
----------------------------------
Inhalation:
Inhalation of vapors may be irritating to the nose and throat. Inhalation of
high concentrations may result in nausea, vomiting, headache, ringing in
the ears, and severe breathing difficulties which may be delayed in onset.
Substernal pain, cough, and hoarseness are also reported. High vapor
concentrations are anesthetic and central nervous system depressants.
Ingestion:
Ingestion causes burning sensation in mouth and stomach, nausea,
vomiting and salivation. Minute amounts aspirated into the lungs can
produce a severe hemorrhagic pneumonitis with severe pulmonary injury
or death.
Skin Contact:
Skin contact results in loss of natural oils and often results in a
characteristic dermatitis. May be absorbed through the skin.
Eye Contact:
Vapors cause eye irritation. Splashes cause severe irritation, possible
corneal burns and eye damage.
Chronic Exposure:
Chronic inhalation can cause headache, loss of appetite, nervousness and
pale skin. Repeated or prolonged skin contact may cause a skin rash.
Repeated exposure of the eyes to high concentrations of vapor may cause
reversible eye damage. Repeated exposure can damage bone marrow,
causing low blood cell count. May damage the liver and kidneys.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or eye problems, or impaired
liver, kidney, blood, or respiratory function may be more susceptible to the
effects of the substance.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Call a physician immediately.
Ingestion:
Aspiration hazard. If swallowed, vomiting may occur spontaneously, but
DO NOT INDUCE. If vomiting occurs, keep head below hips to prevent
aspiration into lungs. Never give anything by mouth to an unconscious
person. Call a physician immediately.
Skin Contact:
Immediately flush skin with plenty of soap and water for at least 15
minutes while removing contaminated clothing and shoes. Get medical
attention. Wash clothing before reuse. Thoroughly clean shoes before
reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting
lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Fire:
Flash point: 29C (84F) CC
Autoignition temperature: 464C (867F)
Flammable limits in air % by volume:
lel: 1.0; uel: 7.0
Explosion:
Above flash point, vapor-air mixtures are explosive within flammable
limits noted above. Contact with strong oxidizers may cause fire. Sealed
containers may rupture when heated. Sensitive to static discharge.
Fire Extinguishing Media:
Dry chemical, foam or carbon dioxide. Water spray may be used to keep
fire exposed containers cool, dilute spills to nonflammable mixtures,
protect personnel attempting to stop leak and disperse vapors.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode. Vapors can flow along
surfaces to distant ignition source and flash back.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition. Wear
appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from
entering. Contain and recover liquid when possible. Use non-sparking
tools and equipment. Collect liquid in an appropriate container or absorb
with an inert material (e. g., vermiculite, dry sand, earth), and place in a
chemical waste container. Do not use combustible materials, such as saw
dust. Do not flush to sewer! If a leak or spill has not ignited, use water
spray to disperse the vapors, to protect personnel attempting to stop leak,
and to flush spills away from exposures. US Regulations (CERCLA)
require reporting spills and releases to soil, water and air in excess of
reportable quantities. The toll free number for the US Coast Guard
National Response Center is (800) 424-8802.
J. T. Baker SOLUSORB庐 solvent adsorbent is recommended for spills of
this product.
7. Handling and Storage
Protect against physical damage. Store in a cool, dry well-ventilated
location, away from any area where the fire hazard may be acute. Outside
or detached storage is preferred. Separate from incompatibles. Containers
should be bonded and grounded for transfers to avoid static sparks.
Storage and use areas should be No Smoking areas. Use non-sparking type
tools and equipment, including explosion proof ventilation. Containers of
this material may be hazardous when empty since they retain product
residues (vapors, liquid); observe all warnings and precautions listed for
the product. Do Not attempt to clean empty containers since residue is
difficult to remove. Do not pressurize, cut, weld, braze, solder, drill, grind
or expose such containers to heat, sparks, flame, static electricity or other
sources of ignition: they may explode and cause injury or death.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
-OSHA Permissible Exposure Limit (PEL):
100 ppm (TWA) xylene
100 ppm (TWA) ethylbenzene
-ACGIH Threshold Limit Value (TLV):
xylene: 100 ppm (TWA) 150 ppm (STEL), A4 - Not classifiable as a
human carcinogen.
ethyl benzene: 100 ppm (TWA) 125 ppm (STEL), A3 - Confirmed Animal
Carcinogen with Unknown Relevance to Humans.
Ventilation System:
A system of local and/or general exhaust is recommended to keep
employee exposures below the Airborne Exposure Limits. Local exhaust
ventilation is generally preferred because it can control the emissions of
the contaminant at its source, preventing dispersion of it into the general
work area. Please refer to the ACGIH document, Industrial Ventilation, A
Manual of Recommended Practices, most recent edition, for details. Use
explosion-proof equipment.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible,
a half-face organic vapor respirator may be worn for up to ten times the
exposure limit, or the maximum use concentration specified by the
appropriate regulatory agency or respirator supplier, whichever is lowest.
A full-face piece organic vapor respirator may be worn up to 50 times the
exposure limit, or the maximum use concentration specified by the
appropriate regulatory agency or respirator supplier, whichever is lowest.
For emergencies or instances where the exposure levels are not known,
use a full-face piece positive-pressure, air-supplied respirator.
WARNING: Air-purifying respirators do not protect workers in oxygen-
deficient atmospheres. Where respirators are required, you must have a
written program covering the basic requirements in the OSHA respirator
standard. These include training, fit testing, medical approval, cleaning,
maintenance, cartridge change schedules, etc. See 29CFR1910.134 for
details.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat,
apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is
possible. Maintain eye wash fountain and quick-drench facilities in work
area.
9. Physical and Chemical Properties
The following physical data is for xylene.
Appearance:
Clear, colorless liquid.
Odor:
Characteristic odor.
Solubility:
Insoluble in water.
Specific Gravity:
0.86 @ 20C/4C
pH:
Not applicable.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
137 - 140C (279 - 284F)
Melting Point:
-25C (-13F)
Vapor Density (Air=1):
3.7
Vapor Pressure (mm Hg):
8 @ 20C (68F)
Evaporation Rate (BuAc=1):
0.7
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Involvement in a fire causes formation of carbon monoxide and
unidentified organic components.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizing agents and strong acids.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
11. Toxicological Information
Toxicological Data:
Xylene: oral rat LD50: 4300 mg/kg; inhalation rat LC50: 5000 ppm/4H;
skin rabbit LD50: > 1700 mg/kg; Irritation eye rabbit: 87 mg mild (Std.
Draize); irritation skin rabbit 500 mg/24 moderate (Std. Draize);
investigated as a tumorigen, mutagen, reproductive effector.
Ethyl benzene: oral rat LD50: 3500 mg/kg; skin rabbit LD50: 17800
uL/kg; investigated as a tumorigen, mutagen, reproductive effector.
Reproductive Toxicity:
May cause teratogenic effects.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
m-Xylene (108-38-3) No No 3
o-Xylene (95-47-6) No No 3
p-Xylene (106-42-3) No No 3
Ethyl Benzene (100-41-4) No No 2B
12. Ecological Information
Environmental Fate:
Following data for xylene: When released into the soil, this material may
evaporate to a moderate extent. When released into the soil, this material
is expected to leach into groundwater. When released into the soil, this
material may biodegrade to a moderate extent. When released into water,
this material may evaporate to a moderate extent. When released into
water, this material may biodegrade to a moderate extent. When released
into the air, this material may be moderately degraded by reaction with
photochemically produced hydroxyl radicals. When released into the air,
this material is expected to have a half-life of less than 1 day. This
material is not expected to significantly bioaccumulate. (mixed xylenes:
octanol / water partition coefficient 3.1 - 3.2; bioconcentration factor =
1.3, eels)
Environmental Toxicity:
For xylene: This material is expected to be slightly toxic to aquatic life.
The LC50/96-hour values for fish are between 10 and 100 mg/l.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be handled as
hazardous waste and sent to a RCRA approved incinerator or disposed in a
RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local
disposal regulations may differ from federal disposal regulations. Dispose
of container and unused contents in accordance with federal, state and
local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: RQ, XYLENES
Hazard Class: 3
UN/NA: UN1307
Packing Group: III
Information reported for product/size: 398LB
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: XYLENES
Hazard Class: 3
UN/NA: UN1307
Packing Group: III
Information reported for product/size: 398LB
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
m-Xylene (108-38-3) Yes Yes Yes Yes
o-Xylene (95-47-6) Yes Yes Yes Yes
p-Xylene (106-42-3) Yes Yes Yes Yes
Ethyl Benzene (100-41-4) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
m-Xylene (108-38-3) Yes Yes No Yes
o-Xylene (95-47-6) Yes Yes No Yes
p-Xylene (106-42-3) Yes Yes No Yes
Ethyl Benzene (100-41-4) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
m-Xylene (108-38-3) No No Yes No
o-Xylene (95-47-6) No No Yes No
p-Xylene (106-42-3) No No Yes No
Ethyl Benzene (100-41-4) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
m-Xylene (108-38-3) 1000 No No
o-Xylene (95-47-6) 1000 No No
p-Xylene (106-42-3) 100 No Yes
Ethyl Benzene (100-41-4) 1000 No No
Chemical Weapons Convention: No TSCA 12(b): Yes CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Mixture / Liquid)
WARNING:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE
STATE OF CALIFORNIA TO CAUSE CANCER.
Australian Hazchem Code: 3[Y]
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the
Controlled Products Regulations (CPR) and the MSDS contains all of the
information required by the CPR.
16. Other Information
NFPA Ratings: Health: 2 Flammability: 3 Reactivity: 0
Label Hazard Warning:
DANGER! HARMFUL OR FATAL IF SWALLOWED. VAPOR
HARMFUL. AFFECTS CENTRAL NERVOUS SYSTEM. CAUSES
SEVERE EYE IRRITATION. CAUSES IRRITATION TO SKIN AND
RESPIRATORY TRACT. MAY BE HARMFUL IF ABSORBED
THROUGH SKIN. CHRONIC EXPOSURE CAN CAUSE ADVERSE
LIVER, KIDNEY, AND BLOOD EFFECTS. FLAMMABLE LIQUID
AND VAPOR.
Label Precautions:
Keep away from heat, sparks and flame.
Avoid contact with eyes, skin and clothing.
Keep container closed.
Use only with adequate ventilation.
Avoid breathing vapor.
Wash thoroughly after handling.
Label First Aid:
Aspiration hazard. If swallowed, vomiting may occur spontaneously, but
DO NOT INDUCE. If vomiting occurs, keep head below hips to prevent
aspiration into lungs. Never give anything by mouth to an unconscious
person. Call a physician immediately. If inhaled, remove to fresh air. If not
breathing, give artificial respiration. If breathing is difficult, give oxygen.
In case of contact, immediately flush eyes or skin with plenty of water for
at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse. In all cases get medical attention
immediately.
Product Use:
Laboratory Reagent.
Revision Information:
No Changes.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or
accuracy. This document is intended only as a guide to the
appropriate precautionary handling of the material by a properly
trained person using this product. Individuals receiving the
information must exercise their independent judgment in determining
its appropriateness for a particular purpose. MALLINCKRODT
BAKER, INC. MAKES NO REPRESENTATIONS OR
WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING
WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR
PURPOSE WITH RESPECT TO THE INFORMATION SET
FORTH HEREIN OR THE PRODUCT TO WHICH THE
INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT
BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES
RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)
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