**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 107-12-0 |Propionitrile | 99 | 203-464-4 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T F
Risk Phrases: 11 23/24/25
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Highly flammable. Toxic by inhalation, in contact with skin and if
swallowed.Possible risks of irreversible effects.
Potential Health Effects
Eye:
Vapors cause eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
May be fatal if swallowed. Contains cyanide.
Inhalation:
Vapors may cause dizziness or suffocation. Vapor or mist is
irritating to the mucous membranes and upper respiratory tract.
Chronic:
May cause cyanosis - a blue-gray coloring of the skin and lips
caused by a lack of oxygen. Massive doses may produce, without
warning, sudden loss of consciousness and prompt death from
respiratory arrest.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. Do NOT use mouth-to-mouth resuscitation. Administer
oxygen. If breathing has ceased apply artificial respiration using
oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively.
Antidote:
Always have a cyanide antidote kit on hand when working with cyanide
compounds. Get medical advice to use. The combination of sodium
thiosulfate and hydroxycobalamin has been used as an effective
antidote.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. During a
fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Will burn if involved in a fire. Use
water spray to keep fire-exposed containers cool. Water may be
ineffective. Material is lighter than water and a fire may be spread
by the use of water. Containers may explode in the heat of a fire.
Flammable liquid and vapor. Vapors may be heavier than air. They
can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. For large fires, use water spray, fog, or
alcohol-resistant foam. Do NOT use water directly on fire. Use water
spray to cool fire-exposed containers. Use foam, dry chemical, or
carbon dioxide. Water may be ineffective. Do NOT use straight streams
of water. Use water spray, dry chemical, carbon dioxide, or
appropriate foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Clean up spills immediately,
observing precautions in the Protective Equipment section. Remove all
sources of ignition. Use a spark-proof tool. Provide ventilation. A
vapor suppressing foam may be used to reduce vapors.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Ground and bond containers when transferring
material. Use spark-proof tools and explosion proof equipment. Empty
containers retain product residue, (liquid and/or vapor), and can be
dangerous. Keep container tightly closed. Keep away from heat, sparks
and flame. Do not get on skin or in eyes. Do not ingest or inhale.
Use with adequate ventilation. Wash clothing before reuse. Do not
pressurize, cut, weld, braze, solder, drill, grind, or expose empty
containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
Flammables-area.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 107-12-0:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Clear liquid
Color: Clear, Colorless Liquid
Odor: Pleasant, ethereal-sweetish odor
pH: Not available.
Vapor Pressure: 40 mmHg @ 23 C
Viscosity: 0.44 mPas 20 deg C
Boiling Point: 97 deg C @ 760.00mm Hg
Freezing/Melting Point: -93 deg C
Autoignition Temperature: 510 deg C ( 950.00 deg F)
Flash Point: 6 deg C ( 42.80 deg F)
Explosion Limits, lower: 3.10 vol %
Explosion Limits, upper: .00 vol %
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density: .7720g/cm3
Molecular Formula: C3H5N
Molecular Weight: 55.08
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, strong
oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong reducing agents, strong acids, strong
bases.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide,
nitrogen.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 107-12-0: UF9625000
LD50/LC50:
CAS# 107-12-0: Draize test, rabbit, eye: 100 mg/24H Moderate; Draize
test, rabbit, skin: 500 mg/24H Mild; Inhalation, mouse: LC50 = 163
ppm/1H; Oral, mouse: LD50 = 35797 ug/kg; Oral, rat: LD50 = 39 mg/kg;
Skin, rabbit: LD50 = 210 uL/kg.
Carcinogenicity:
Propionitrile -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Estimated BCF Value = 0.78. This value suggests that propionitrile is
not expected to bioconcentrate in aquatic organisms. Estimated Koc
Value = 1.2. This suggests that it will not be expected to adsorb
significantly to soil.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: PROPIONITRILE
Hazard Class: 3 (6.1)
UN Number: 2404
Packing Group: II
IMO
Shipping Name: PROPIONITRILE
Hazard Class: 3.2 (6.1)
UN Number: 2404
Packing Group: II
RID/ADR
Shipping Name: PROPIONITRILE
Hazard Class: 3
UN Number: 2404
Packing group: II
USA RQ: CAS# 107-12-0: 10 lb final RQ; 4.54 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T F
Risk Phrases:
R 11 Highly flammable.
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
Safety Phrases:
S 9 Keep container in a well-ventilated place.
S 16 Keep away from sources of ignition - No
smoking.
S 27 Take off immediately all contaminated clothing.
S 33 Take precautionary measures against static
discharges.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 107-12-0: 1
Canada
CAS# 107-12-0 is listed on Canada's DSL List.
CAS# 107-12-0 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 107-12-0 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 12/08/1998 Revision #2 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
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|
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| ALL MSDS PAGES IN THIS GROUP
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p-Phenylenediamine, 99% (uv-vis)
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3-Fluoro-2-methylaniline, 97%
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| 104-24-5 |
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| 6575-09-3 |
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DL-3-Hydroxy-4-Methoxymandelic Acid, 99%
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Diethyl Sulfate, 95% (GC)
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L-(-)-Perillic Acid, 95%
| 7694-45-3 |
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m-Phenylenediamine, 99+%
| 108-45-2 |
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Trimethyl Orthoformate, 99%
| 149-73-5 |
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5-Methyl-2-nitrophenol, 97%
| 700-38-9 |
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N-(4-nitrobenzoyl)-l-glutamic acid diethyl ester, 98%
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5,5-Diphenyl-2-Thiohydantoin, 99%
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Propionic acid-d6, 98.5+ atom% d
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2-Amino-6-methylmercaptopurine
| 1198-47-6 |
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Manganese(II) bromide, anhydrous, 99%
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2-Methylthiophene, 98%
| 554-14-3 |
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Cyclohexyl Mercaptan, 99+%
| 1569-69-3 |
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Trans-4-Octyl-Alpha-Chloro-4'- Ethoxystilbene, 99+%
| 33468-15-4 |
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2,5-Dihydroxybenzaldehyde, 99%
| 1194-98-5 |
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Cyclopentyl Bromide, 98%
| 137-43-9 |
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