**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 54-11-5 |Nicotine | | 200-193-3 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T+
Risk Phrases: 25 27
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Toxic if swallowed. Very toxic in contact with skin.Hygroscopic.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be fatal if absorbed through the
skin.
Ingestion:
May be fatal if swallowed. May cause adverse effects of the
musculature. May cause severe digestive tract irritation with
abdominal pain, nausea, vomiting and diarrhea. May cause tremors and
convulsions. May cause muscle paralysis, respiratory failure, and
possible death.
Exposure causes initial nervous system stimulation followed by severe
CNS depression. May cause ataxia and incoordination.
Inhalation:
May cause effects similar to those described for ingestion.
Chronic:
May cause digestive tract and cardiac disturbances.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower lids. Get medical aid.
Skin:
Flush skin with plenty of soap and water for at least 15 minutes
while removing contaminated clothing and shoes. Get medical aid if
irritation develops or persists. Discard contaminated clothing in a
manner which limits further exposure. Destroy contaminated shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air
immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.
Antidote:
No specific antidote exists.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Can form explosive mixtures at temperatures above
the flashpoint.
Extinguishing Media:
For small fires, use water spray, dry chemical, carbon dioxide or
chemical foam. Water or foam may cause frothing.
Autoignition Temperature: 240 deg C ( 464.00 deg F)
Flash Point: 101 deg C ( 213.80 deg F)
NFPA Rating: health-4; flammability-1; reactivity-0
Explosion Limits, Lower: .70 vol %
Upper: 4.00 vol %
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Wear a self contained breathing apparatus and appropriate Personal
protection. (See Exposure Controls, Personal Protection section).
Remove all sources of ignition. Absorb spill using an absorbent,
non-combustible material such as earth, sand, or vermiculite.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Ground and bond
containers when transferring material. Use spark-proof tools and
explosion proof equipment. Do not reuse this container. Do not get
on skin or in eyes. Do not ingest or inhale.
Storage:
Keep away from sources of ignition. Keep from contact with oxidizing
materials. Store in a cool, dry, well-ventilated area away from
incompatible substances. Keep away from strong acids.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne
concentrations below the permissible exposure limits.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133.
Skin:
Wear impervious gloves.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR
1910.134. Always use a NIOSH-approved respirator when
necessary.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Appearance: clear light yellow
Odor: Slight fish odor when warm.
pH: Not available.
Vapor Pressure: 1 mm Hg @ 61.8C
Vapor Density: 5.61 (air=1)
Evaporation Rate: Not available.
Viscosity: Not available.
Boiling Point: 247 deg C @ 760.00MM HG
Freezing/Melting Point: -80 deg C
Decomposition Temperature: Not available.
Solubility: IN WATER: MISCIBLE BELOW 60??C
Specific Gravity/Density: 1.0100g/cm3
Molecular Formula: C10H14N2
Molecular Weight: 162.23
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong acids, strong oxidizers.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 54-11-5: QS5250000
LD50/LC50:
CAS# 54-11-5: Oral, mouse: LD50 = 3340 ug/kg; Oral, rat: LD50 = 50
mg/kg; Skin, rabbit: LD50 = 50 mg/kg; Skin, rat: LD50 = 140 mg/kg.
Carcinogenicity:
Nicotine -
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
For further information, contact Fisher Scientific.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
CDG/CPL
IMO
Shipping Name: NICOTINE
Hazard Class: 6.1
UN Number: 1654
Packing Group: II
IATA
Shipping Name: NICOTINE
Hazard Class: 6.1
UN Number: 1654
Packing Group: II
RID/ADR
Shipping Name: NICOTINE
Dangerous Goods Code: 6.1(90B)
UN Number: 1654
Canadian TDG
Shipping Name: NICOTINE
Hazard Class: 6.1
UN Number: UN1654
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+
Risk Phrases:
R 25 Toxic if swallowed.
R 27 Very toxic in contact with skin.
Safety Phrases:
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident of if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 54-11-5:
Canada
CAS# 54-11-5 is listed on Canada's DSL/NDSL List.
This product has a WHMIS classification of D1A, D2B.
CAS# 54-11-5 is listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 54-11-5:. OEL-ARAB Republic of Egypt:TWA 0.5 mg/m3;Skin. OEL-AUS
TRALIA:TWA 0.5 mg/m3;Skin. OEL-BELGIUM:TWA 0.5 mg/m3;Skin. OEL-DENMARK
:TWA 0.5 mg/m3;Skin. OEL-FINLAND:TWA 0.5 mg/m3;STEL 1.5 mg/m3;Skin. OE
L-FRANCE:TWA 0.5 mg/m3;Skin. OEL-GERMANY:TWA 0.07 ppm (0.5 mg/m3);Skin
. OEL-HUNGARY:STEL 0.5 mg/m3;Skin. OEL-THE NETHERLANDS:TWA 0.07 ppm (0
.5 mg/m3);Skin. OEL-THE PHILIPPINES:TWA 0.5 mg/m3;Skin. OEL-POLAND:TWA
0.5 mg/m3. OEL-SWITZERLAND:TWA 0.07 ppm (0.5 mg/m3);STEL 0.1 ppm;Skin
. OEL-THAILAND:TWA 0.5 mg/m3. OEL-TURKEY:TWA 0.5 mg/m3;Skin
D KINGDOM:TWA 0.5 mg/m3;STEL 1.5 mg/m3;Skin. OEL IN BULGARIA, COLOMBIA
, JORDAN, KOREA check ACGIH TLV. OEL IN NEW ZEALAND, SINGAPORE, VIETNA
M check ACGI TLV
US FEDERAL
TSCA
CAS# 54-11-5 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 3/02/1995 Revision #3 Date: 9/02/1997
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
|
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Cyclen, 97%
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9-Aminoacridine hemihydrate, 98%
| 90-45-9 |
|
3-Bromothiophene, 97+%
| 872-31-1 |
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3-Aminobenzoic acid, 99+%
| 99-05-8 |
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DL-Menthol, 99%
| 1490-04-6 |
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| 13138-45-9 |
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| 1313-99-1 |
|
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| 7662-51-3 |
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Germanium Dioxide, 99.999%, electronic grade
| 1310-53-8 |
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| 318-98-9 |
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| 6262-51-7 |
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| 10101-97-0 |
|
Phenylarsonic acid, 97%
| 98-05-5 |
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| 76841-99-1 |
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| 54-11-5 |
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| |
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| 821-10-3 |
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| 24936-44-5 |
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| 95-16-9 |
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Fast garnet GBC, zinc chloride salt
| |
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| 537-67-7 |
|
Pentafluorobenzonitrile, 97+%
| 773-82-0 |
|
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| 619-67-0 |
|
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| 9010-98-4 |
|
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| 696-54-8 |
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| 527-17-3 |
|
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| 2459-09-8 |
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| 485-47-2 |
|
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| 7789-40-4 |
|
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| 13826-35-2 |
|
Trans-2-Heptenal, 97%
| 18829-55-5 |
|
syn-2-Pyridinealdoxime, 99+%
| 873-69-8 |
|
N-Acetylthiourea, 99.5%
| 591-08-2 |
|
1-(2,2-Diethoxyethyl)guanidine sulfate , 99%
| 52225-73-7 |
|
Nitric acid, red fuming
| 7697-37-2 |
|
Nitric acid, 20-70%
| 7697-37-2 |
|
Boc-Glycine, 99+%
| 4530-20-5 |
|
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| 538-24-9 |
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| 621-03-4 |
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| 14003-34-0 |
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| 98-95-3 |
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