**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 60388-53-6 |DL-Amethopterin hydrate | ca 100 | 262-213-7 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T
Risk Phrases: 46 61
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
May cause heritable genetic damage. May cause harm to the unborn
child.Hygroscopic (absorbs moisture from the air).Light sensitive.The
toxicological properties of this material have not been fully
investigated.Mutagen.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be absorbed through the skin in
harmful amounts.
Ingestion:
May cause irritation of the digestive tract. The toxicological
properties of this substance have not been fully investigated.
Exposure may cause anemia and other blood abnormalities.
Inhalation:
May cause respiratory tract irritation. May cause effects similar to
those described for ingestion. The toxicological properties of this
substance have not been fully investigated.
Chronic:
May alter genetic material. Possible risk of harm to the unborn
child.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and
drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes,
skin, and clothing. Keep container tightly closed. Avoid ingestion
and inhalation. Store protected from light.
Storage:
Store in a tightly closed container. Deep freeze (below -20C).
Store protected from moisture. Store protected from light.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 60388-53-6:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Powder
Color: orange - yellow crystalline powder
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 195 deg C dec
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: > 195 deg C
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C20H22N8O5.xH2O
Molecular Weight: 454.44
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions.
Conditions to Avoid:
Incompatible materials, light, dust generation, excess heat, exposure
to moist air or water.
Incompatibilities with Other Materials:
Strong acids, strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, carbon dioxide.
Hazardous Polymerization: Has not been reported
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 60388-53-6: MA1224100
LD50/LC50:
Not available.
Carcinogenicity:
DL-Amethopterin hydrate -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing Group: III
IMO
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing Group: III
RID/ADR
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing group: III
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 46 May cause heritable genetic damage.
R 61 May cause harm to the unborn child.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 60388-53-6: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 60388-53-6 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 60388-53-6 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 7/06/1999 Revision #3 Date: 4/14/2005
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
2',4'-Dimethylacetoacetanilide
| 97-36-9 |
|
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| 490-79-9 |
|
Mandelonitrile, tech.
| 532-28-5 |
|
N-Acetylsulfanilyl Chloride, 99%(Titr.)
| 121-60-8 |
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DL-Amethopterin hydrate
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|
D-Ethionine, 98%
| 535-32-0 |
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2,4,4-Trimethyl-2-Oxazoline, 99%
| 1772-43-6 |
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4-Nitrophenyl Isothiocyanate
| 2131-61-5 |
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Norephedrine Hydrochloride, 98% (Titr.)
| 3195-78-6 |
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Diethyl phenylphosphonite, 99%
| 1638-86-4 |
|
2,3-Dichlorobutane, 98%
| 7581-97-7 |
|
1,1-Diphenylethylene, 99% (GC)
| 530-48-3 |
|
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|
1-Hydroxybenzotriazole, 98%
| 2592-95-2 |
|
3',4'-Dimethylacetophenone, 97%
| 3637-01-2 |
|
4-Chloro-alpha-methylbenzylamine, 97%
| 6299-02-1 |
|
4-Phenylazophenol, 97% (UV-Vis)
| 1689-82-3 |
|
Diethyl oxalate, 99%
| 95-92-1 |
|
l-Lysine dihydrochloride, 99%
| 657-26-1 |
|
2-Iodobenzoyl Chloride, 98+%
| 609-67-6 |
|
2-Chloronicotinamide, 98%
| 10366-35-5 |
|
2-Thenylmercaptan, 98%
| 6258-63-5 |
|
2-??4-(4-dimethylaminophenyl)-1,3- butadienyl??-3-ethylbenzothiazolium
| 114720-33-1 |
|
3-Chloro-2-methylpropionitrile, tech., 85+%
| 7659-45-2 |
|
Sodium Deuteroxide (30 wt. % Solution in D2O), 99+ Atom % D
| 7732-18-5 |
|
Succinyl chloride, ca 95 %
| 543-20-4 |
|
2-Chloro-4-fluorobenzyl chloride, 98%
| 93286-22-7 |
|
1-(2,4-Dichlorophenyl)-1-Propanone 95%
| 37885-41-9 |
|
3-Ethoxyphenol, 98% (gc)
| 621-34-1 |
|
Rhodium on alumina powder (5% rh)
| |
|
Dibutyltin bis(2-ethylhexanoate)
| 2781-10-4 |
|
2,4-Diamino-6-phenyl-s-triazine, 99+% (titr.)
| 91-76-9 |
|
Ethyl Methylcarbamate, 99% (GC)
| 105-40-8 |
|
(4-Aminophenyl)trimethylammonium iodide hydrochloride, 94%
| 62654-12-0 |
|
2,2,5,5-Tetramethyl-3-Pyrrolidine- Carboxamide
| 702-96-5 |
|
Celestine blue
| 1562-90-9 |
|
1-(2-Furyl)-1,3-butanedione
| 25790-35-6 |
|
N-alpha-Benzoyl-dl-arginine-p-nitroanilide hydrochloride, 99+%
| 911-77-3 |
|
Hydroxy Naphthol Blue, Disodium Salt, P.A.
| 29114-66-7 |
|
Linoleic acid (techn), 60% (gc)
| 60-33-3 |
|
Octafluorotoluene, 98%
| 434-64-0 |
|
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| 124-65-2 |
|
2-Methoxyethyl Acetoacetate, 97%
| 22502-03-0 |
|
2-(2-Thienyl)pyridine, 97+%
| 3319-99-1 |
|
Naphthol green b
| 19381-50-1 |
|
2,4,5-Trimethyloxazole, 95%
| 20662-84-4 |
|
P-Arsanilic Acid, 99% (UV-Vis)
| 98-50-0 |
|
(S)-(+)-10-Methyl-1(9)-Octal-2-One,98.5%
| 4087-39-2 |
|
Indole-3-pyruvic acid , 97%
| 392-12-1 |
|
|