**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 79-06-1 |Acrylamide | 40 | 201-173-7 |
|----------------|--------------------------------------|----------|-----------|
| 7732-18-5 |Water | 60 | 231-791-2 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: T
Risk Phrases: 45 46 24/25 48/23/24/25
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
May cause cancer. May cause heritable genetic damage. Toxic in
contact with skin and if swallowed. Toxic : danger of serious damage
to health by prolonged exposure through inhalation, contact with
skin and if swallowed.Cancer suspect agent.Light sensitive.Air
sensitive.Hygroscopic (absorbs moisture from the air).
Potential Health Effects
Eye:
Causes eye irritation. Acrylamide can be absorbed through the eyes
and overexposure will produce the signs and symptoms of neurotoxicity
described below.
Skin:
May cause skin sensitization, an allergic reaction, which becomes
evident upon re-exposure to this material. Acrylamide is readily
absorbed through unbroken skin and can cause nervous system effects
(neurotoxicity). These effects can result from a single overexposure
but are more likely after repeated exposures to small amounts over a
period of days or weeks. Signs and symptoms of overexposure include
increased sweating of the hands and feet, numbness, tingling and
weakness in the extremities, unsteady gait and decreased reflexes.
If the exposure route is dermal, the symptoms may be preceded by
peeling and redness of the skin at the areas of exposure, normally
the hands and feet.
Ingestion:
Harmful if swallowed.
Inhalation:
Acrylamide tends to sublime (go directly from solid to vapor form)
which may lead to inhalation exposure. Acrylamide can be absorbed
through the lungs and overexposure will produce the signs and
symptoms of neurotoxicity described above.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. May cause
cancer according to animal studies. Adverse reproductive effects have
been reported in animals. Prolonged or repeated exposure affects the
nervous system.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with plenty of water for
at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Either acute or chronic exposure may lead to weak or absent
reflexes, positive Romberg's sign, loss of vibration and position
senses and numbness and tingling of the limbs. An early sign of
toxic effects is peeling of the skin of the fingertips.
Antidote:
Pyridoxine (vitamin B6), pyruvate, and N-acetylcysteine have been
used to reduce the toxicity of acrylamide in experimental studies,
but are unproven.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
Containers can build up pressure if exposed to heat and/or fire. As
in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Use water spray to keep fire-exposed containers
cool. Dust can be an explosion hazard when exposed to heat or flame.
Combustible solid. Approach fire from upwind to avoid hazardous
vapors and toxic decomposition products. Fight fire from maximum
distance or use unmanned hose holders or monitor nozzles.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Sweep up or absorb material, then place into a suitable clean, dry,
closed container for disposal. Avoid generating dusty conditions.
Remove all sources of ignition. Isolate area and deny entry. Provide
ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Minimize dust generation and accumulation. Do not
get in eyes, on skin, or on clothing. Keep container tightly closed.
Keep away from heat, sparks and flame. Do not ingest or inhale. Use
only in a chemical fume hood.
Storage:
Keep away from heat, sparks, and flame. Do not store in direct
sunlight. Keep refrigerated. (Store below 4C/39F.) Keep from
contact with oxidizing materials. Store in a cool, dry,
well-ventilated area away from incompatible substances. Keep away
from acids. Do not store near alkaline substances. Keep away from
polymerization catalysts. Should not be exposed to temperatures
above 122F (50C).
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other
engineering controls to control airborne levels below recommended
exposure limits. Facilities storing or utilizing this material should
be equipped with an eyewash facility and a safety shower. Utilize a
closed system process where feasible.
Exposure Limits
CAS# 79-06-1:
United Kingdom, WEL - TWA: 0.3 mg/m3 TWA
United Kingdom, WEL - STEL: 0.9 mg/m3 STEL
United States OSHA: 0.3 mg/m3 TWA
Belgium - TWA: 0.03 mg/m3 VLE
France - VME: 0.1 ppm VME; 0.3 mg/m3 VME
Germany: 0.06 mg/m3 TWA (solid); 0.03 mg/m3 TWA
Germany: Skin absorber
Japan: 0.1 mg/m3 OEL
Malaysia: 0.03 mg/m3 TWA
Russia: 0.2 mg/m3 TWA
Spain: 0.03 mg/m3 VLA-ED
CAS# 7732-18-5:
Personal Protective Equipment
Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: colorless
Odor: Odorless.
pH: 6 - 7
Vapor Pressure: .007 mm Hg @ 25 deg C
Viscosity: Not available.
Boiling Point: 125 deg C @ 25 mm Hg
Freezing/Melting Point: 83 - 85 deg C (decomposes
Autoignition Temperature: 464 deg F ( 240.00 deg C)
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: 84 deg C
Solubility in water: Soluble.
Specific Gravity/Density: 1.122 @ 30C
Molecular Formula: C3H5NO
Molecular Weight: 71.08
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable. However may polymerize explosively if heated to the melting
point. May polymerize on exposure to light.
Conditions to Avoid:
Light, ignition sources, moisture, exposure to air, heat.
Incompatibilities with Other Materials:
Metals, oxidizing agents, reducing agents, acids, bases, peroxides.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, carbon dioxide, ammonia and/or
derivatives, hydrogen gas.
Hazardous Polymerization: May occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 79-06-1: AS3325000
CAS# 7732-18-5: ZC0110000
LD50/LC50:
CAS# 79-06-1: Draize test, rabbit, eye: 100 mg/24H Moderate; Draize
test, rabbit, skin: 50 mg/3D Mild; Draize test, rabbit, skin: 500
mg/24H Mild; Oral, mouse: LD50 = 107 mg/kg; Oral, rabbit: LD50 = 150
mg/kg; Oral, rat: LD50 = 124 mg/kg; Skin, rabbit: LD50 = 1680 uL/kg;
Skin, rat: LD50 = 400 mg/kg.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
Carcinogenicity:
Acrylamide -
ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to
California: carcinogen, initial date 1/1/90
NTP: Suspect carcinogen
IARC: Group 2A carcinogen
Water -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Other
No information available.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Products which are considered hazardous for supply are classified as Special
Waste and the disposal of such chemicals is covered by regulations which may
vary according to location. Contact a specialist disposal company or the local
waste regulator for advice. Empty containers must be decontaminated before
returning for recycling.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
USA RQ: CAS# 79-06-1: 5000 lb final RQ; 2270 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 45 May cause cancer.
R 46 May cause heritable genetic damage.
R 24/25 Toxic in contact with skin and if swallowed.
R 48/23/24/25 Toxic : danger of serious damage to
health by prolonged exposure through inhalation,
contact with skin and if swallowed.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 79-06-1: 3
CAS# 7732-18-5: No information available.
Canada
CAS# 79-06-1 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
CAS# 79-06-1 is listed on Canada's Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 79-06-1 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
MSDS Creation Date: 4/17/1998 Revision #5 Date: 11/19/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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