| MSDS | : | ETHYLENE GLYCOL, C00057 | | CAS | : | 107-21-1 | | NAME | : | ethylene glycol (sara 313) (cercla)
supdat:of sev poisoning. death may occur in extreme cases. target organ
ing 2:chronic:teratogenic:ethylene glycol is considered to be animal
ing 3:levs were given in drinking water. inhal & dermal expos have
ing 4:malformations in animals. tox info:oral tox:slightly tox to humans
ing 5:for humans is 1.6 g/kg by mouth. dermal ld50:essentially non-tox to
ing 6:ld50 in rabbits is 9.5 g/kg. long-term, high lev expos prdced
ing 7:teratogenicity:prced pre-implantation loss, delayed ossification,
ing 8:mice when admin by gavage/in drinking water during organogenesis.
first aid proc:induce vomit in uncon person. note to phys:principal tox
ing 10:are kidney dmg & metabolic acidosis. ethanol is antidotal,
ing 11:metabolities of ethylene glycol in liver. ethanol should be given
ing 12:bicarbonate, at rate of about 10ml/hr. desired therapeutic lev of
ing 13:hemodialysis may be reqd. pulm edema w/hypoxemia has been
ing 14:poisoning w/ethylene glycol. mechanism has not been elucidated but
ing 15:origin in several cases. resp support w/mechan vent & pos
ing 16:of acidosis is essential.
spill proc:water spray to disperse vaps. contain spill to facilitate
ing 18:matls, vacuum truck, etc. avoid runoff into storm sewers &
ing 19:natl response ctr (800-424-8802) if qty spilled is equal to or
ing 20:cercla "superfund":ethylene glycol-5000 lb/day.
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HOECHST CELANSE POLYESTER INTE -- ETHYLENE GLYCOL, C00057
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Material Safety Data Sheet
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MSDS Num: CCSFJ
MSDS NAME: ETHYLENE GLYCOL, C00057
Responsible Party
Name: HOECHST CELANSE POLYESTER INTERMEDIATES
Address: 4600 US HIGHWAY 421 NORTH
Box: 327
City: WILMINGTON NC 28402
Info Phone: 910-341-5500
Emergency Phone Number: 800-835-5235;800-424-9300(CHEMTREC)
Published: Y
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Contractor Summary
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Name: HOECHST CELANSE POLYESTER INTERMEDIATES
Address: 4600 US HIGHWAY 421 NORTH
Box: 327
City: WILMINGTON NC 28402
Phone: 910-341-5500
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Ingredients
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Cas: 107-21-1
RTECS #: KW2975000
Name: ETHYLENE GLYCOL (SARA 313) (CERCLA)
% Wt: 99.5
OSHA PEL: N/K (FP N)
ACGIH TLV: C 50 PPM, VAPOR
EPA Rpt Qty: 1 LB
DOT Rpt Qty: 1 LB
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Name: SUPDAT:OF SEV POISONING. DEATH MAY OCCUR IN EXTREME CASES. TARGET ORGAN
EFTS:CNS, KIDNEY, LIVER, FETUS.
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Name: ING 2:CHRONIC:TERATOGENIC:ETHYLENE GLYCOL IS CONSIDERED TO BE ANIMAL
TERATOGEN BASED ON STUDIES IN WHICH HIGH
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Name: ING 3:LEVS WERE GIVEN IN DRINKING WATER. INHAL & DERMAL EXPOS HAVE
NOT PRCED SIGNIFICANT FETOTOXICITY/
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Name: ING 4:MALFORMATIONS IN ANIMALS. TOX INFO:ORAL TOX:SLIGHTLY TOX TO HUMANS
BY INGEST. ESTIMATED AVERAGE LETHAL DOSE
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Name: ING 5:FOR HUMANS IS 1.6 G/KG BY MOUTH. DERMAL LD50:ESSENTIALLY NON-TOX TO
ANIMALS BY SKIN ABSORP. ACUTE DERMAL
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Name: ING 6:LD50 IN RABBITS IS 9.5 G/KG. LONG-TERM, HIGH LEV EXPOS PRDCED
KIDNEY INJURY IN RATS BUT NOT IN MICE.
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Name: ING 7:TERATOGENICITY:PRCED PRE-IMPLANTATION LOSS, DELAYED OSSIFICATION,
& CONGENITAL MALFORMATIONS IN RATS &
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Name: ING 8:MICE WHEN ADMIN BY GAVAGE/IN DRINKING WATER DURING ORGANOGENESIS.
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Name: FIRST AID PROC:INDUCE VOMIT IN UNCON PERSON. NOTE TO PHYS:PRINCIPAL TOX
EFTS OF ETHYLENE GLYCOL, WHEN SWALLOWED,
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Name: ING 10:ARE KIDNEY DMG & METABOLIC ACIDOSIS. ETHANOL IS ANTIDOTAL,
& EARLY ADMIN MAY BLOCK FORMATION OF TOXIC
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Name: ING 11:METABOLITIES OF ETHYLENE GLYCOL IN LIVER. ETHANOL SHOULD BE GIVEN
INTRAVENOUSLY, AS 5% SOLN IN SODIUM
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Name: ING 12:BICARBONATE, AT RATE OF ABOUT 10ML/HR. DESIRED THERAPEUTIC LEV OF
ETHANOL IN BLOOD IS 100MG/DL.
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Name: ING 13:HEMODIALYSIS MAY BE REQD. PULM EDEMA W/HYPOXEMIA HAS BEEN
DESCRIBED IN NUMBER OF PATIENTS FOLLOWING
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Name: ING 14:POISONING W/ETHYLENE GLYCOL. MECHANISM HAS NOT BEEN ELUCIDATED BUT
IT APPEARS TO BE NONCARDIOGENIC IN
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Name: ING 15:ORIGIN IN SEVERAL CASES. RESP SUPPORT W/MECHAN VENT & POS
& EXPIRATORY PRESS MAY BE APPLIED. CORRECTION
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Name: ING 16:OF ACIDOSIS IS ESSENTIAL.
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Name: SPILL PROC:WATER SPRAY TO DISPERSE VAPS. CONTAIN SPILL TO FACILITATE
CLEANUP. CLEANUP METH MAY INCL ABSORB
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Name: ING 18:MATLS, VACUUM TRUCK, ETC. AVOID RUNOFF INTO STORM SEWERS &
DITCHES WHICH LEAD TO NATURAL WATERWAYS. CALL
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Name: ING 19:NATL RESPONSE CTR (800-424-8802) IF QTY SPILLED IS EQUAL TO OR
GREATER THAN REPORTABLE QTY (RQ) UNDER
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Name: ING 20:CERCLA "SUPERFUND":ETHYLENE GLYCOL-5000 LB/DAY.
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Health Hazards Data
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LD50 LC50 Mixture: NONE SPECIFIED BY MANUFACTURER.
Route Of Entry Inds - Inhalation: YES
Skin: YES
Ingestion: YES
Carcinogenicity Inds - NTP: NO
IARC: NO
OSHA: NO
Effects of Exposure: ACUTE:SKIN:MAY CAUSE SLIGHT IRRIT. EYES:MAY CAUSE SLIGHT
IRRIT. INHAL:INHAL OF MISTS/HIGH CONCS OF VAPS (E.G., FROM HOT OPERATIONS)
MAY CAUSE UPPER RESP TRACT IRRIT, HDCH/NAUS. INGEST:INGEST OF LG QTY S MAY BE
HARMFUL, & IN EXTREME POISONING, MAY BE FATAL; CAUSES CNS DEPRESS,
CARDIOPULM EFTS, & KIDNEY (EFTS OF OVEREXP)
Explanation Of Carcinogenicity: NOT RELEVANT.
Signs And Symptions Of Overexposure: HLTH HAZ:& LIVER DMG. SIGNS &
SYMPS OF EXPOS:INCIDENTAL INGEST OF SM AMTS OF ETHYLENE GLYCOL IS NOT LIKELY
TO CAUSE ANY SIGNIFICANT HLTH EFTS. INGEST OF LG QTYS MAY RSLT IN
IRRITABILITY, MENTAL SLUGGI SHNESS, DIZZ, MALAISE, ABDOM/BACK PAIN.CHANGES IN
URINE OUTPUT & APPEAR, FLUID RETENTION, JAUNDICE (YELLOWISH (SUPDAT)
Medical Cond Aggravated By Exposure: EXPOSURE TO THIS CHEMICAL MAY AGGRAVATE
PREEXISTING SKIN AND RESPIRATORY CONDITIONS.
First Aid: SKIN:WASH W/SOAP & WATER AFTER HNDLG MATL. IF PERSISTANT IRRIT
DEVELOPS, GET MED ATTN. EYES:FLUSH W/WATER FOR @ LST 15 MINS. IF PERSISTANT
IRRIT DEVELOPS, GET MED ATTN. INHAL:REMOVE TO FRESH AIR. IF N OT BRTHG, GIVE
ARTF RESP. IF BRTHG IS DFCLT, GIVE OXYG. GET MED ATTN IMMED. INGEST:IF LG
QTYS OF THIS MATL ARE SWALLOWED, CALL PHYS IMMED. DO NOT INDUCE VOMIT. NEVER
GIVE ANYTHING BY MOUTH OR
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Handling and Disposal
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Spill Release Procedures: ELIM IGNIT SOURCES. AVOID EYE/SKIN CONT; SEE "EXPOS
CTLS/PERSONAL PROT SECTION", FOR RESP INFO. PLACE LEAKING CNTNRS IN
WELL-VENTILATED AREA W/SPILL CONTAM. IF FIRE POTNTL EXISTS, BLANKET SPILL
W/ALCO HOL-TYPE AQUEOUS FILM-FORMING FOAM/USE
Neutralizing Agent: NONE SPECIFIED BY MANUFACTURER.
Waste Disposal Methods: ALL NOTIFICATION, CLEAN-UP & DISP SHOULD BE CARRIED
OUT I/A/W FEDERAL, STATE & LOCAL REGS. PREFERRED METHS OF WASTE DISP ARE
INCIN/BIOLOGICAL TREATMENT IN FEDERAL/STATE APPROVED FACILITY.
Handling And Storage Precautions: KEEP ALL CNTNRS TIGHTLY CLSD WHEN NOT IN USE.
STORE OUT OF DIRECT SUNLIGHT & ON AN IMPERMEABLE FLOOR. USE ONLY
DOT-APPRVD CNTNRS.
Other Precautions: DO NOT STORE W/INCOMPAT MATLS; SEE "STABILITY &
REACTIVITY SECTION". USE W/ADEQ VENT. ALWAYS OPEN CNTNRS SLOWLY TO ALLOW ANY
EXCESS PRESS TO VENT. AVOID BRTHG VAP/MIST. AVOID CONT W/EYES, SKIN/CLTHG.
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Fire and Explosion Hazard Information
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Flash Point Method: CC
Flash Point Text: 232F,111C
Lower Limits: 3.2%
Upper Limits: 15.3%
Extinguishing Media: USE CARBON DIOXIDE, DRY CHEMICAL FOR SM FIRES;
ALCOHOL-TYPE AQUEOUS FILM-FORMING FOAM/WATER SPRAY FOR LG FIRES.
Fire Fighting Procedures: NIOSH APPRVD SCBA & FULL PROT EQUIP (FP N). WATER
SPRAY CAN BE USED TO REDUCE INTENSITY OF FLAMES & TO DILUTE SPILLS TO
NONFLAMM MIX. USE WATER SPRAY (SUPDAT)
Unusual Fire/Explosion Hazard: CARBON MONOXIDE.
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Control Measures
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Respiratory Protection: USE A RESPIRATOR APPROVED BY NIOSH TO MAINTAIN EXPOSURE
BELOW RECOMMENDED LIMITS.
Ventilation: GEN/DILUTION VENT IS FREQUENTLY INSUFFICIENT AS SOLE MEANS OF
CONTROLLING EMPLOYEE EXPOS. LOC VENT IS USUALLY PREFERRED.
Protective Gloves: NITRILE RUBB+POLYVINYL CHLORIDE.
Eye Protection: ANSI APPRVD CHEM WORKERS GOGGLES (FP N).
Other Protective Equipment: IMPERVIOUS CLTHG & GLOVES TO PVNT RPTD/PRLNGD
CONTACT. ANSI APPRVD EYE WASH & DELUGE SHOWER (FP N).
Work Hygienic Practices: WASH THORO W/SOAP & WATER AFTER HNDLG. DECONTAM SOILED
CLTHG THORO BEFORE RE-USE. DESTROY CONTAMD LEATHER CLTHG.
Supplemental Safety and Health: FIRE FIGHT PROC:TO COOL FIRE-EXPOS STRUCTURES
& VESSELS. CAUTION! SPRAYING W/FOAM/WATER CAN CAUSE FROTHING. MATLS TO
AVOID:OXIDIZING AGENTS; ACETIC ANHYDRIDE; STRONG ACIDS & BASES @ HIGH
TEMPS; OTHER MATLS REACTIVE W/HYDROXYL CMPDS. EFTS OF OVEREXP:SKIN COLOR),
KIDNEY & LIVER DMG, RESP FAILURE, & UNCON ARE EVID
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Physical/Chemical Properties
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B.P. Text: 387F,197C
M.P/F.P Text: 9F,-13C
Vapor Pres: <0.1 @ 20C
Vapor Density: 2.2
Spec Gravity: 1.115 (20/20)
Evaporation Rate & Reference: NOT KNOWN
Solubility in Water: COMPLETE
Appearance and Odor: CLEAR, COLORLESS LIQUID. FAINT ODOR.
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Reactivity Data
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Stability Indicator: YES
Stability Condition To Avoid: HEAT, SPARKS AND OPEN FLAMES.
Materials To Avoid: SULFURIC ACID & OTHER DEHYDRATING AGENTS; NITRIC ACID;
OXYG, HYDROGEN PEROXIDE, PERCHLORIC ACID & OTHER STRONG (SUPDAT)
Hazardous Decomposition Products: CARBON MONOXIDE.
Hazardous Polymerization Indicator: NO
Conditions To Avoid Polymerization: NOT RELEVANT.
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Toxicological Information
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Ecological Information
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MSDS Transport Information
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Regulatory Information
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Other Information
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HAZCOM Label
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MSDS NAME: ETHYLENE GLYCOL, C00057
Company: HOECHST CELANSE POLYESTER INTERMEDIATES
Street: 4600 US HIGHWAY 421 NORTH
PO Box: 327
City: WILMINGTON NC
Zipcode: 28402
Health Emergency Phone: 800-835-5235;800-424-9300(CHEMTREC)
Label Required IND: Y
Date Of Label Review: 11/18/1996
Status Code: C
Label Date: 11/18/1996
Origination Code: G
Chronic Hazard IND: Y
Eye Protection IND: YES
Skin Protection IND: YES
Signal Word: WARNING
Respiratory Protection IND: YES
Health Hazard: Moderate
Contact Hazard: Slight
Fire Hazard: Slight
Reactivity Hazard: None
Hazard And Precautions: ACUTE:SKIN:MAY SLIGHT IRRITATION. EYES:MAY CAUSE SLIGHT
IRRITATION. INHALATION:INHALATION OF MISTS/HIGH CONCENTRATIONS OF VAPORS
(E.G., FROM HOT OPERATIONS) MAY CAUSE UPPER RESPIRATORY TRACT IRRITATIO N,
HEADACHE/NAUSIA. INGESTION:INGESTIONOF LARGE QUANTITIES MAY BE HARMFUL, &
IN EXTREME POISONING, MAY BE FATAL; CAUSES CNS DEPRESS, CARDIOPULMONARY
EFFECTS, & KIDNEY AND LIVER DAMAGE. CHRONIC:ETHYLEN E GLYCOL IS
CONSIDERED TO BE AN ANIMAL TERATOGEN.
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Disclaimer (provided with this information by the compiling agencies): This
information is formulated for use by elements of the Department of Defense.
The United States of America in no manner whatsoever expressly or implied
warrants, states, or intends said information to have any application, use or
viability by or to any person or persons outside the Department of Defense
nor any person or persons contracting with any instrumentality of the United
States of America and disclaims all liability for such use. Any person
utilizing this instruction who is not a military or civilian employee of the
United States of America should seek competent professional advice to verify
and assume responsibility for the suitability of this information to their
particular situation regardless of similarity to a corresponding Department
of Defense or other government situation.
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