=====================  Product Identification  =====================

MSDS NAME:NEOMYCIN SULFATE, N1876
NIIN:01-371-5045
Status Code:A
MSDS Number: CJQPQ
=== Responsible Party ===
Company:SIGMA CHEMICAL CO
Box:14508
City:ST LOUIS
State:MO
ZIP:63178
Country:US
Info Phone Num:314-771-5765
Emergency Phone Num:314-771-5765
CAGE:21076
=== Contractor Identification ===
Company:SIGMA CHEMICAL COMPANY
Address:3050 SPRUCE ST
Box:14508
City:ST LOUIS
State:MO
ZIP:63178
Country:US
Phone:314-771-5765
CAGE:21076

=============  Composition/Information on Ingredients  =============

Name:NEOMYCIN SULFATE. LD50:(ORAL,RAT) >4325 MG/KG (SUPPLIER
    DATA).
CAS:1405-10-3
RTECS #:QP4375000
ACGIH TLV:2 MG/M3 TWA

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:SEE INGREDIENTS & TOX INFORMATION.
Routes of Entry: Inhalation:YES  Skin:YES  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:ACUTE: MAY BE HARMFUL BY INHALATION,
    INGESTION OR SKIN ABSORPTION. CAUSES EYE AND SKIN IRRITATION.
    MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER RESPIRATORY
    TRACT. MAY CAUSE ALLERGIC RESPIRATOR Y AND SKIN REACTIONS. CHRONIC:
    POSSIBLERISK OF CONGENITAL MALFORMATION IN THE FETUS. TARGET
    ORGAN(S): KIDNEYS, EARS. TO THE BEST OF MFR'S KNOWLEDGE, THE
    CHEMICAL, PHYSICAL AND TOXICOLOGICAL PROPERTIES  HAVE NOT BEEN
    THOROUGHLY INVESTIGATED. TARGET ORGAN DATA: SENSE ORGANS AND
    SPECIAL SENSES (CHANGE IN ACUITY); BEHAVIORAL (CONVULSIONS OR
    EFFECT ON SEIZURE THRESHOLD).
Effects of Overexposure:SEE HEALTH HAZARDS.

=======================  First Aid Measures  =======================

Eyes: IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF WATER FOR AT
    LEAST 15 MINUTES. SKIN: IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF
    WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED CLOTHING
    AND SH OES. WASH CONTAMINATED CLOTHING BEFORE REUSE. INHALATION:
    REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL RESPIRATION.
    IF BREATHING IS DIFFICULT, GIVE OXYGEN. INGESTION: WASH OUT MOUTH
    WITH WATE R PROVIDE PERSON IS CONSCIOUS. CALL MD.

=====================  Fire Fighting Measures  =====================

Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL POWDER OR
    APPROPRIATE FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
    EQUIPMENT .
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

==================  Accidental Release Measures  ==================

Spill Release Procedures:EVACUATE AREA. WEAR NIOSH APPROVED
    SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY RUBBER
    GLOVES. WEAR DISPOSABLE COVERALLS AND DISCARD THEM AFTER USE. SWEEP
    UP, PLACE IN A BAG AND HOLD FOR  WASTE DISPOSAL. AVOID RAISING
    DUST. VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS
    COMPLETE.

======================	Handling and Storage  ======================

Handling and Storage Precautions:DO NOT BREATHE DUST. DO NOT GET IN
    EYES, ON SKIN, ON CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE.
    KEEP TIGHTLY CLOSED. STORE IN A COOL, DRY PLACE.
Other Precautions:HARMFUL. POSSIBLE RISK OF HARM TO THE UNBORN CHILD.
    MAY CAUSE SENSITIZATION BY INHALATION AND SKIN CONTACT. IRRITATING
    TO EYES, RESPIRATORY SYSTEM AND SKIN. IN CASE OF ACCIDENT OR IF YOU
    FEEL UNWELL,  SEEK MEDICAL ADVICE IMMEDIATELY (SHOW LABEL WHERE
    POSSIBLE).

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:WEAR APPROPRIATE NIOSH APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES & FULL LENGTH
    FACESHIELD .
Other Protective Equipment:ANSI APPROVED EYE WASH & DELUGE SHOWER .
    WEAR OTHER SUITABLE PROTECTIVE CLOTHING.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
PHYSICAL DATA: SOLUBILITY: IN ETHER - INSOLUBLE; IN ETHANOL - SLIGHTLY
    SOLUBLE; IN ACETONE - INSOLUBLE.

==================  Physical/Chemical Properties  ==================

Solubility in Water:SOLUBLE
Appearance and Odor:SOLID.

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS.
Stability Condition to Avoid:HEAT. MAY DECOMPOSE ON EXPOSURE TO LIGHT.
Hazardous Decomposition Products:TOXIC FUMES OF: CARBON MONOXIDE,
    CARBON DIOXIDE, NITROGEN OXIDES, SULFUR OXIDES.
Conditions to Avoid Polymerization:WILL NOT OCCUR.

===================  Toxicological Information	===================

Toxicological Information:AMINOGLYCOSIDES ARE ASSOC W/SIGNIFICANT
    NEPHROTOXICITY &/OR OTOTOXICITY. IRRIT DATA: SKIN-HMN 6 MG/3D-I MLD
    - 85DKA8 -,127,1977. TOX DATA: LD50:(SCU,RAT) 200 MG/KG - ARZNAD
    12,597,1962. LD50:(ORAL,MUS ) >8 GM(BASE)/KG - AACHAX -,138,1963.
    LD50:(IPR,MUS) 305 MG/KG - ANTCAO 8,198,1958. LD50:(SCU,MUS) 190
    MG/KG - ANTBAL 18,444,1973. LD50:(IVN,MUS) 17400 UG/KG - AITEAT
    10,947,1962. LD50:(IMS,MUS) 142 M G/KG - AIMDAP 119,493,1967.
    LD50:(ICE,MUS) 32 MG/KG - TXAPA9 7,361,1965. LD50:(IMS,GPG) >250
    MG/KG - TXAPA9 33,320,1975. ONLY SELECTED RTECS DATA IS PRESENTED
    HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPL ETE INFO.

=====================  Ecological Information  =====================

Ecological:DATA NOT YET AVAILABLE.

====================  Disposal Considerations  ====================

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
    SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
    AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
    ENVIRONMENTAL REGULATIONS.

===================  MSDS Transport Information  ===================

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
    INFORMATION.

=====================  Regulatory Information  =====================

Federal Regulatory Information:EUROPEAN INFO: HARMFUL R 63 - POSS RISK
    OF HARM TO UNBORN CHILD. R 42/43 - MAY CAUSE SENSIT BY INHAL & SKIN
    CONT. R 36/37/38 - IRRIT TO EYES, RESP SYS & SKIN. S 45 - IN CASE
    OF ACCIDENT/IF YOU FEEL UN WELL, SEEK MED ADVICE IMMED (SHOW LBL
    WHERE POSS). S 26 - IN CASE OF CONT W/EYES, RINSE IMMED W/PLENTY OF
    WATER & SEEK MED ADVICE. S 36/37/39 - WEAR SUITABLE PROT CLTHG,
    GLOVES & EYE/FACE PROT. REVIEW S, STDS & REGS: OEL=MAK. EPA FIFRA
    1988 PESTICIDE SUBJECT TO REGISTRATION/RE-REGISTRATION FEREAC 54,
    7740,1989. NOES 1983: HZD X3700; NIS 23; TNF 3566; NOS 33; TNE
    180078; TFE 143663. NOES 1983: HZD X9498; NIS 5; TNF 1014; (OTHER
    INFO)
State Regulatory Information:CALIFORNIA PROPOSITION 65: THIS PRODUCT IS
    OR CONTAINS CHEMICAL(S) KNOWN TO THE STATE OF CALIFORNIA TO CAUSE
    DEVELOPMENTAL TOXICITY.

=======================  Other Information  =======================

 Disclaimer (provided with this information by the compiling agencies):
 This information is formulated for use by elements of the Department
 of Defense.  The United States of America in no manner whatsoever,
 expressly or implied, warrants this information to be accurate and
 disclaims all liability for its use.  Any person utilizing this
 document should seek competent professional advice to verify and
 assume responsibility for the suitability of this information to their
 particular situation.

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