===================== Product Identification =====================
MSDS NAME:ACCESS TROPONIN I CALIBRATOR, CALALOG NO. 33325
Status Code:A
MSDS Number: CKYQS
=== Responsible Party ===
Company:BECKMAN INSTRUMENTS, INC.
Address:1000 LAKE HAZELTINE DRIVE
City:CHASKA
State:MN
ZIP:55318-1084
Country:US
Info Phone Num:(612) 448-4848
Emergency Phone Num:800-854-3633
Resp. Party Other MSDS Num.:(K263)
CAGE:TO606
=== Contractor Identification ===
Company:BECKMAN INSTRUMENTS, INC.
Address:1000 LAKE HAZELTINE DRIVE
Box:City:CHASKA
State:MN
ZIP:55318-1084
Country:US
Phone:(612) 448-4848
CAGE:TO606
Company:SANOFI DIAGNOSTICS PASTEUR
Address:1000 LAKE HAZELTINE DR
Box:City:CHASKA
State:MN
ZIP:55318
Country:US
Phone:800-666-7111; 612-448-4848
CAGE:0TEN9
============= Composition/Information on Ingredients =============
Name:MISC. INORGANIC SALT (I.E., NA2HP04)
< Wt:1.
Name:SUCCINIC ACID (BUTANEDIOIC ACID) C4H6O4
CAS:110-15-6
RTECS #:WM4900000
< Wt:2.
Name:WATER, H2O
CAS:7732-18-5
RTECS #:ZC0110000
> Wt:75.
Name:HUMAN SERUM
< Wt:18.
Name:SODIUM HYDROXIDE, NAOH
CAS:1310-73-2
RTECS #:WB4900000
< Wt:2.
EPA Rpt Qty:1000 LBS
DOT Rpt Qty:1000 LBS
Name:HUMAN SOURCE MATERIAL, HUMAN TROPONIN I
< Wt:1.
Name:KATHON (5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE) CAS #:
26172-55-4 AND (2-METHYL-4-ISOTHIAZOLIN-3-ONE) CAS #: 2682-20-4
< Wt:1.
===================== Hazards Identification =====================
LD50 LC50 Mixture:LD50: 3350 MG/KG (ORAL, RAT) (KATHON)
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:HUMAN SERUM: POTENTIALLY INFECTIOUS
MATERIAL IF SKIN IS PENETRATED AND/OR MUCOUS MEMBRANES ARE EXPOSED.
MATERIAL USED IN THE PREPARATION OF THIS PRODUCT HAS BEEN TESTED
AND FOUND NON-REATIVE FOR HEPAT ITIS B SURFACE ANTIGEN (HBSAG),
ANTIBODIES TO HEPATITIS C VIRUS (HCV), AND ANTIBODIES TO HUMAN
IMMUNODEFICIENCY VIRUS (HIV-1 AND HIV-2). BECAUSE NO KNOWN TEST
METHOD CAN OFFER COMPLETE ASSURANCE THAT INFECTIOUS AGENTS ARE
ABSENT, HANDLE RAEGENTS AND PATIENT SAMPLES AS IF THEY ARE CAPABLE
OF TRANSMITTING INFECTIOUS DISEASE. WHEN USING THIS PRODUCT, FOLLOW
UNIVERSAL PRECAUTIONS FOR POTENTIALLY INFEC TIOUS (SIGNS & SYMPTOMS
OF OVEREXPOSURE)
Effects of Overexposure:HEALTH HAZARDS ACUTE AND CHRONIC (CONT):
MATERIALS ACCORDING TO THE CENTERS FOR DISEASE CONTROL (CDC) /
NATIONAL INSTITUTE FOR HEALTH (NIH) GUIDELINES AND OCCUPATIONAL
SAFETY AND HEALTH ADMINISTRATION (OSHA) REGULATIONS. SODIUM
HYDROXIDE: TOXIC CORROSIVE. HARMFUL IF SWALLOWED, INHALED, OR
ABSORBED THROUGH THE SKIN. DESTRUCTIVE TO TISSUE. CAUSTIC CAPABLE
OF CAUSING SEVERE BURNS TO MUCOUS MEMBRANES , THE UPPER RESPIRATORY
TRACT, EYES AND SKIN. HUMAN SOURCE MATERIAL: POTENTIALLY
INFECTIOUS MATERIAL IF SKIN IS PENETRATED AND / OR MUCOUS MEMBRANES
ARE EXPOSED. MATERIAL USED IN THE PREPARATION OF T HIS PRODUCT HAS
(TOXICOLOGICAL INFO)
======================= First Aid Measures =======================
First Aid:EYE: FLUSH EYES WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15
MINUTES. ENSURE ADEQUATE FLUSHING BY SEPARATING THE EYELIDS WITH
FINGERS. SKIN: REMOVE CONTAMINATED CLOTHING. WASH AFFECTED AREA(S)
THOROU GHLY WITH SOAP AND WATER AND RINSE WITH WATER. MAY CAUSE
ALLERGIC SKIN REACTIONS. SWALLOWING: WASH OUT MOUTH WITH WATER
PROVIDED PERSON IS CONCIOUS. INHALATION: REMOVE FROM EXPOSURE AREA
TO FRESH AIR. HEALTH EFFECTS: SYMPTOMS OF OVEREXPOSURE MAY
INCLUDE: HEADACHE, RESPIRATORY CONGESTION AND EYE IRRITATION. SKIN
CONTACT MAY RESULT IN DERMATITIS.
===================== Fire Fighting Measures =====================
Extinguishing Media:WATER, CO2 (CARBON DIOXIDE), DRY CHEMICAL OR
ALCOHOL FOAM.
Fire Fighting Procedures:SELF CONTAINED BREATHING APPARATUS (NIOSH
APPROVED - ) AND PROTECTIVE CLOTHING SHOULD BE WORN.
Unusual Fire/Explosion Hazard:COMBUSTION PRODUCTS: NOT FLAMMABLE
(EXCEPT PACKAGING MATERIALS).
================== Accidental Release Measures ==================
Spill Release Procedures:HUMAN-BASED MATERIAL SPILLS SHOULD BE TREATED
AS POTENTIALLY INFECTIOUS MATERIAL; COVER SPILL WITH ABSORBENT
MATERIAL, PLACE IN A SUITABLE CONTAINER AND FOLLOW WITH AN
APPLICATION OF APPROPRIATE DISIN FECTANT. BROKEN GLASS SHOULD BE
TREATED AS SHARPS; SWEEP UP SOLIDS AND PLACE IN SUITABLE SHARPS
CONTAINER. USE UNIVERSAL PRECAUTIONS AND GOOD CLINICAL LABORATORY
PRACTICES. (OTHER INFORMATION)
====================== Handling and Storage ======================
Handling and Storage Precautions:STORING: STORE AT 2 - 10 C. HANDLING
PRECAUTIONS: FOLLOW PROPER LABORATORY SAFETY GUIDELINES FOR
CHEMICALS AND BIOLOGICALS. WEAR GLOVES TO PREVENT SKIN CONTACT.
AVOID SPLASHING OR GENERATION OF AEROS OLS.
Other Precautions:REFER TO ASSAY MANUAL FOR PRODUCT INSERT FOR
ADDITIONAL PRODUCT INFORMATION. REFER TO CHEMICAL SPECIFIC MSDS FOR
ADDITIONAL DATA.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:A NIOSH APPROVED RESPIRATOR APPROPRIATE FOR THE
EXPOSURE OF CONCERN .
Ventilation:NORMAL LAB VENTILATION IS ADEQUATE UNLESS AEROSOLS ARE
GENERATED. IF AEROSOLS ARE GENERATED, CONSULT WITH YOUR SAFETY AND
ENVIRONMENTAL HEALTH OFFICER.
Protective Gloves:APPROPRIATE TO PREVENT SKIN CONTACT.
Eye Protection:ANSI APPROVED CHEMICAL SAFETY GOGGLES AND FULL FACE
SHIELD .
Other Protective Equipment:EYEWASH AND DELUGE SHOWER MEETING ANSI
DESIGN CRITERIA . LAB COAT OR GOWN TO PREVENT SKIN CONTACT.
Work Hygienic Practices:WASH HANDS AFTER REMOVING GLOVES.
Supplemental Safety and Health
================== Physical/Chemical Properties ==================
pH:BETWEEN 5-9
Solubility in Water:ALL CHEM REAGENTS SOLUBLE
Appearance and Odor:STANDARD - LYOPHILIZED IN GLASS VIALS. ODOR: NONE.
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
Stability Condition to Avoid:NOT APPLICABLE.
=================== Toxicological Information ===================
Toxicological Information:SIGNS AND SYMPTOMS OF OVEREXPOSURE (CONT):
BEEN TESTED AND FOUND NON-REATIVE FOR HEPATITIS B SURFACE ANTIGEN
(HBSAG), ANTIBODIES TO HEPATITIS C VIRUS (HCV), AND ANTIBODIES TO
HUMAN IMMUNODEFICIENCY VI RUS (HIV-1 AND HIV-2). BECAUSE NO KNOWN
TEST METHOD CAN OFFER COMPLETE ASSURANCE THAT INFECTIOUS AGENTS ARE
ABSENT, HANDLE REAGENTS AND PATIENT SAMPLES AS IF THEY ARE CAPABLE
OF TRANSMITTING INFECTIOU S DISEASE. WHEN USING THIS PRODUCT,
FOLLOW UNIVERSAL PRECAUTIONS FOR POTENTIALLY INFECTIOUS MATERIALS
ACCORDING TO THE CENTERS FOR DISEASE CONTROL (CDC) / NATIONAL
INSTITUTES FOR HEALTH (NIH) GUIDELIN ES AND OCCUPATIONAL
(ECOLOGICAL INFO)
===================== Ecological Information =====================
Ecological:N/P. TOXICOLOGICAL INFO (CONT): SAFETY AND HEALTH
ADMINISTRATION (OSHA) REGULATIONS. KATHON: THIS PRESERVATIVE IS A
MIXTURE OF INGREDIENTS. CORROSIVE, IRRITANT, POTENTIAL SKIN
SENSITIZER AND I S CONSIDERED TOXIC IN ITS CONCENTRATED FORM. LD50:
3350 MG/KG (ORAL, RAT), LC50: 0.33 MG/L/4 HRS (RAT). MISC.
INORGANIC SALT: MAY CAUSE TEMPORARY EYE, SKIN AND UPPER RESPIRATORY
TRACT IRRITATION. SU CCINIC ACID: WEAK ACID. MILD MUCOUS MEMBRANE
AND SKIN IRRITANT. NOT HAZARDOUS AT KIT CONCENTRATION. WATER: NOT
APPLICABLE.
==================== Disposal Considerations ====================
Waste Disposal Methods:DISPOSE OF MATERIAL IN ACCORDANCE WITH LOCAL,
STATE AND FEDERAL REGULATIONS. CONTACT YOUR SAFETY AND
ENVIRONMENTAL HEALTH OFFICER FOR DISPOSAL PROCEDURES.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.
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