MATERIAL SAFETY DATA SHEET
SULFENTRAZONE IN TOLUENE
MSDS Ref. No.: F17-67-4
Date Approved: 11/24/2004
Revision No.: 3
This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication
Standard, 29 CFR 1910.1200; the EC directive, 2001/58/EC and other regulatory requirements. The
information contained herein is for the concentrate as packaged, unless otherwise noted.
1. PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME: SULFENTRAZONE IN TOLUENE
PRODUCT CODE: None Assigned
ACTIVE INGREDIENT(S): Sulfentrazone
CHEMICAL FAMILY: Aryl Triazolinones
MOLECULAR FORMULA: (sulfentrazone)
SYNONYMS: FMC 97285; F6285; N-[2,4-dichloro-5-[4-difluoromethyl)-4,5-
dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-
yl]phenyl]methanesulfonamide; IUPAC: N-[2,4-dichloro-5-(4-
difluoromethyl-3-methyl-5-oxo-4,5-dihydro-[1,2,4]triazol-1-
yl)phenyl]methane sulfonamide
ALTERNATE PRODUCT NAME(S): Step 7
MANUFACTURER EMERGENCY TELEPHONE NUMBERS
FMC CORPORATION (800) 424-9300 (CHEMTREC - U.S.A. & Canada)
Agricultural Products Group (202) 483-7616 (CHEMTREC - All Other Countries)
1735 Market Street (800) 331-3148 (FMC - U.S.A. & Canada)
Philadelphia, PA 19103 (716) 735-3765 (Reverse charges - FMC)
(215) 299 6000 (General Information)
2. HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW:
鈥? Tan mixture with a sharp odor.
鈥? Extremely flammable (see Flash Point in Section 9, "Physical and Chemical Properties" below).
鈥? Thermal decomposition and burning may form toxic by-products.
鈥? For large exposures or fire, wear personal protective equipment.
鈥? Highly toxic to algae.
鈥? Slightly toxic to fish and aquatic organisms. Keep out of drains and water courses.
鈥? Expected to be severely irritating to the eyes and skin.
Page 1 of 11
SULFENTRAZONE IN TOLUENE (F17-67-4) Date: 11/24/2004
POTENTIAL HEALTH EFFECTS: Effects from overexposure may result from
swallowing or contact with the eyes or skin. This product is expected to be severely irritating to the eyes
and skin. Symptoms of overexposure include convulsions, decreased locomotion, tearing, increased
sensitivity to touch, bloody discharge from the nose, and incoordination.
MEDICAL CONDITIONS AGGRAVATED: None presently known.
3. COMPOSITION / INFORMATION ON INGREDIENTS
Chemical Name CAS# Wt.% EC No. EC Class
Sulfentrazone 122836-35-5 10 - 18 None Not classified
Toluene 108-88-3 77 - 85 203-625-9 R11-38-48/20-63-65-67; S2-
36/37-46-62
1-(2,4-Dichloro-5-aminophenyl)- 111992-18-8 1-2 None Not classified
4-difluoromethyl-4,5-dihydro-3-
methyl-1H-1,2,4-triazol-5-one
Pyridine 110-86-1 1-2 203-809-9 R11, 20/21/22; S2, 26, 28
Methane sulfonyl chloride 124-63-0 1-2 204-706-1 None
4. FIRST AID MEASURES
EYES: Immediately flush with water for at least 15 minutes, lifting the upper and lower eyelids
intermittently. See a medical doctor immediately.
SKIN: Immediately flush with plenty of water while removing contaminated clothing and/or shoes, and
thoroughly wash with soap and water. See a medical doctor immediately.
INGESTION: Rinse mouth with water. Dilute by giving 1 or 2 glasses of water. Do not induce
vomiting. Never give anything by mouth to an unconscious person. See a medical doctor immediately.
INHALATION: Remove to fresh air. If breathing difficulty or discomfort occurs and persists,
contact a medical doctor.
NOTES TO MEDICAL DOCTOR: This product is expected to have low oral and dermal
toxicity. It is expected to be severely irritating to the eyes and skin. Contains toluene which can produce a
severe pneumonitis if aspirated during vomiting. Consideration should be given to gastric lavage with an
endotracheal tube in place. Treatment is otherwise controlled removal of exposure followed by
symptomatic and supportive care.
Page 2 of 11
SULFENTRAZONE IN TOLUENE (F17-67-4) Date: 11/24/2004
5. FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA: Foam, CO2 or dry chemical. Soft stream water fog only if
necessary. Contain all runoff.
FIRE / EXPLOSION HAZARDS: Extremely flammable. Avoid exposure to heat sources.
FIRE FIGHTING PROCEDURES: Isolate fire area. Evacuate downwind. Wear full
protective clothing and self-contained breathing apparatus. Do not breathe smoke, gases or vapors
generated.
6. ACCIDENTAL RELEASE MEASURES
RELEASE NOTES: Isolate and post spill area. Remove ignition sources. Wear protective
clothing and personal protective equipment as prescribed in Section 8, "Exposure Controls/Personal
Protection". Keep unprotected persons and animals out of the area.
Keep material out of lakes, streams, ponds and sewer drains. Dike to confine spill and absorb with a non-
combustible absorbent such as clay, sand or soil. Vacuum, shovel or pump waste into a drum and label
contents for disposal.
To clean and neutralize spill area, tools and equipment, wash with industrial detergent and water, and add
the solution to the drums of waste already collected. Dispose of drummed waste according to the method
outlined in Section 13, Disposal Considerations
7. HANDLING AND STORAGE
HANDLING AND STORAGE: Store in a cool, dry well-ventilated place. Do not use or store
near heat, open flame or hot surfaces. Store in original containers only. Do not contaminate other materials,
or allow this material to be contaminated, by improper storage or handling.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE LIMITS
Chemical Name ACGIH OSHA Supplier
Toluene 50 ppm (TWA) (skin) 200 ppm (PEL)
300 ppm (STEL)
Page 3 of 11
SULFENTRAZONE IN TOLUENE (F17-67-4) Date: 11/24/2004
Chemical Name ACGIH OSHA Supplier
Pyridine 5 ppm (PEL)
ENGINEERING CONTROLS: Use local exhaust at all process locations where vapor or
mist may be emitted.
PERSONAL PROTECTIVE EQUIPMENT
EYES AND FACE: For splash, mist, vapor or dust exposure wear chemical protective
goggles or a face shield.
RESPIRATORY: For splash, spray or mist exposure wear, as a minimum, a properly
fitted half-face or full-face air-purifying respirator with organic vapor or acid/gas cartridge
(approved by U.S. NIOSH/MSHA, EU CEN or comparable certification organization). Respirator
use and selection must be based on airborne concentrations. For unknown or emergency situations,
use a self-contained breathing apparatus (SCBA).
PROTECTIVE CLOTHING: Depending upon concentrations encountered, wear
coveralls or long-sleeved uniform and head covering. Wear Tychem庐 9400 suit for dermal
protection. PVC and neoprene may be suitable for splash protection, but will be permeated quickly
by toluene. Leather items - such as shoes, belts and watchbands - that become contaminated must
be removed and destroyed.
GLOVES: Wear chemical protective gloves such as Silvershield庐 brand or neoprene.
Thoroughly wash the outside of gloves with soap and water prior to removal. Inspect regularly for
leaks.
WORK HYGIENIC PRACTICES: Clean water should be available for washing in case of
eye or skin contamination. Wash skin prior to eating, drinking or using tobacco. Shower at the end of the
workday.
9. PHYSICAL AND CHEMICAL PROPERTIES
Sharp
ODOR:
Tan mixture
APPEARANCE:
43.3掳C (110.6掳F) (toluene)
BOILING POINT:
7.2 lb/gal.
DENSITY / WEIGHT PER VOLUME:
4.4 掳C (40 掳F) (CC)toluene
FLASH POINT:
123掳C (253掳F) (sulfentrazone)
MELTING POINT:
387.19 (Step 7)
MOLECULAR WEIGHT:
Page 4 of 11
SULFENTRAZONE IN TOLUENE (F17-67-4) Date: 11/24/2004
10. STABILITY AND REACTIVITY
CONDITIONS TO AVOID: Excessive heat and fire.
STABILITY: Stable
POLYMERIZATION: Will not occur
HAZARDOUS DECOMPOSITION PRODUCTS: Carbon monoxide, carbon dioxide, nitrogen oxides,
sulfur oxides, hydrogen chloride, hydrogen
fluoride.
11. TOXICOLOGICAL INFORMATION
EYE EFFECTS: Expected to be severely irritating.
SKIN EFFECTS: Expected to be severely irritating.
DERMAL LD50: sulfentrazone: > 2,000 mg/kg (rabbit)
ORAL LD50: sulfentrazone: 2,689 mg/kg (rat)
INHALATION LC50: sulfentrazone: > 4.13 mg/l (4 h) Maximum attainable concentration - zero
mortality
ACUTE EFFECTS FROM OVEREXPOSURE: This product is expected to have low
oral and dermal toxicity. It is expected to be severely irritating to the eyes and skin. Signs of toxicity in
laboratory animals included clonic convulsions, ataxia, hypersensitivity to touch, chromorhinorrhea,
abdominogenital staining, decreased locomotion, lacrimation, nasal discharge, and squinting eyes. Effects
observed in laboratory animals after acute inhalation of toluene included mucous membrane irritation,
motor incoordination, prostration, changes in respiratory rate, changes in serum and blood enzyme
activities, elevated blood glucose and packed cell volume, decreased body weight and death. Vomiting after
ingestion of this product may cause aspiration of toluene into the lungs, which may result in fatal
pulmonary edema. Inhalation exposure to pyridine caused irritation to the mucous membranes and ocular
and upper respiratory tract irritation. High oral doses of pyridine caused severe vomiting, diarrhea,
delirium, hyperpyrexia, pulmonary edema and tracheobronchitis. Symptoms of exposure to methane
sulfonyl chloride include burning sensations, coughing, wheezing, laryngitis, shortness of breath, headache,
nausea and vomiting.
CHRONIC EFFECTS FROM OVEREXPOSURE: No data available for the
mixture. Sulfentrazone was not carcinogenic in lifetime feeding studies with laboratory animals, nor was it
found to be mutagenic in a battery of tests. In a reproduction study, sulfentrazone produced adverse effects
on the growth and survival of the offspring, decreased male fertility and oligospermia at 25 mg/kg/day, and
35 mg/kg/day. Sulfentrazone was found to be fetotoxic in oral and dermal developmental toxicity studies;
the fetal NOELS were 10 mg/kg/day and 100 mg/kg/day, respectively. At labeled use rates and practices of
mixing and applying, expected exposure to farm workers is at least one hundred times lower than the doses
that produced effects in laboratory animals. Chronic exposure to toluene may cause headaches, dizziness,
loss of sensations or feelings (such as numbness), and liver and kidney damage. Inhalation of toluene
vapors at high doses have also resulted in an increased incidence of malformations and decreased fetal
Page 5 of 11
SULFENTRAZONE IN TOLUENE (F17-67-4) Date: 11/24/2004
weight in laboratory animals. Pyridine was evaluated in a battery of mutagenic tests, and it is considered to
have an equivocal mutagenic potential. Exposure to pyridine may cause transient central nervous system
effects, with symptoms such as nervousness, insomnia, headache and coma. Chronic exposure to pyridine
may result in liver and kidney damage. Chronic respiratory conditions, such as asthma, may be aggravated
due to exposure to methane sulfonyl chloride.
CARCINOGENICITY:
NTP: Not listed
IARC: Not listed
OSHA: Not listed
OTHER: Not Listed (ACGIH)
12. ECOLOGICAL INFORMATION
No data available for the mixture. Data presented below are based on sulfentrazone, FMC 97267 (5-Amino)
or toluene, as noted.
ENVIRONMENTAL DATA: Sulfentrazone is stable in soil (half-life = 18 months). In water,
sulfentrazone is stable to hydrolysis over the pH range of 5 to 9; however, it will readily undergo photolysis
(half-life < 0.5 day). Sulfentrazone has a low affinity for organic matter (Koc = 43), but is mobile only in
soils with high sand content. The potential for sulfentrazone to bioaccumulate is very low, having a Log
Pow of 1.48, and a bioconcentration factor of 1.1 - 2.0.
Toluene is expected to readily volatilize from both soil and water. Toluene is minimally soluble in water,
readily bioavailable, and not expected to bioconcentrate. It is not expected to adsorb to soil and may leach
to groundwater. high levels of toluene in soil may inhibit biodegradation. Degradation in groundwater may
be slow.
ECOTOXICOLOGICAL INFORMATION: Sulfentrazone is slightly toxic to fish and
aquatic arthropods, with LC50 values ranging from 60.4 mg/L to > 130 mg/L. Sulfentrazone has a very low
order of toxicity to upland game birds (oral LD50 > 2,250 mg/kg).
FMC 97267 (5-Amino) is slightly toxic to rainbow trout with an acute 96-hour LC50 = 64 mg/L (estimated),
and moderately to very highly toxic to algae with EC50 values ranging from 0.031 to 32.9 mg/L.
Care should be taken to avoid contamination of the aquatic environment.
Toluene is expected to have low toxicity to aquatic and estuarine species. LC50 values, in fish, range from
6.41 to 240 mg/L and, to invertebrates, from 4.3 to 313 mg/L.
Pyridine is expected to have low toxicity to aquatic species (96-hour LC50 = 93.8 mg/L, fathead minnow).
13. DISPOSAL CONSIDERATIONS
DISPOSAL METHOD: Open dumping or burning of this material or its packaging is prohibited.
If spilled material cannot be recovered and reused, an acceptable method of disposal is to incinerate in
accordance with local, state and national laws and regulations. However, because acceptable methods of
Page 6 of 11
SULFENTRAZONE IN TOLUENE (F17-67-4) Date: 11/24/2004
disposal may vary by location, and regulatory requirements may change, the appropriate agencies should be
contacted prior to disposal.
EMPTY CONTAINER: Containers which held this material may be cleaned by being triple-
rinsed, and recycled, with the rinsate being incinerated. Do not cut or weld metal containers. Vapors that
form may create an explosion hazard.
14. TRANSPORT INFORMATION
U.S. DEPARTMENT OF TRANSPORTATION (DOT)
Non-Bulk
PACKAGING TYPE:
Toluene mixture
PROPER SHIPPING NAME:
3
PRIMARY HAZARD CLASS / DIVISION:
UN 1294
UN/NA NUMBER:
II
PACKING GROUP:
3
LABEL(S):
3
PLACARD(S):
Toluene mixture, UN 1294
MARKING(S):
Bulk
PACKAGING TYPE:
Toluene mixture
PROPER SHIPPING NAME:
3
PRIMARY HAZARD CLASS / DIVISION:
UN 1294
UN/NA NUMBER:
II
PACKING GROUP:
3
LABEL(S):
3
PLACARD(S):
1294
MARKING(S):
Toluene
REPORTABLE QUANTITY (RQ):
Toluene is in an RQ quantity at 1,176.5
ADDITIONAL INFORMATION:
pounds (163.4 gallons) per package.
Pyridine would be in an "RQ" quantity at
50,000 pounds (6,944 gallons).
INTERNATIONAL MARITIME DANGEROUS GOODS (IMDG)
Non-Bulk
PACKAGING TYPE:
Page 7 of 11
SULFENTRAZONE IN TOLUENE (F17-67-4) Date: 11/24/2004
Toluene mixture
PROPER SHIPPING NAME:
3
PRIMARY HAZARD CLASS / DIVISION:
UN 1294
UN/NA NUMBER:
II
PACKING GROUP:
3
LABEL(S):
3
PLACARD(S):
Toluene mixture, UN 1294
MARKING(S):
EmS Number: F-E, S-D
ADDITIONAL INFORMATION:
ADR - EUROPEAN AGREEMENT CONCERNING THE
INTERNATIONAL CARRIAGE OF DANGEROUS GOODS BY ROAD
Non-Bulk
PACKAGING TYPE:
Toluene mixture
PROPER SHIPPING NAME:
3
PRIMARY HAZARD CLASS / DIVISION:
F1
CLASSIFICATION CODE:
UN1294
UN/NA NUMBER:
II
PACKING GROUP:
33
HAZARD IDENTIFICATION NUMBER:
3
LABEL(S):
3
PLACARD(S):
UN 1294
MARKING(S):
INTERNATIONAL CIVIL AVIATION ORGANIZATION (ICAO) /
INTERNATIONAL AIR TRANSPORT ASSOCIATION (IATA)
Non-Bulk
PACKAGING TYPE:
Toluene mixture
PROPER SHIPPING NAME:
3
PRIMARY HAZARD CLASS / DIVISION:
UN1294
UN/NA NUMBER:
II
PACKING GROUP:
3
LABEL(S):
Y305 / 1L
LIMITED QUANTITY:
305 / 5L
LIMITED QUANTITY: PASSENGER / CARGO:
Page 8 of 11
SULFENTRAZONE IN TOLUENE (F17-67-4) Date: 11/24/2004
307 / 60L
LIMITED QUANTITY: CARGO:
Marks: Toluene mixture, UN1294
ADDITIONAL INFORMATION:
15. REGULATORY INFORMATION
UNITED STATES
SARA TITLE III (SUPERFUND AMENDMENTS AND REAUTHORIZATION ACT)
SECTION 302 EXTREMELY HAZARDOUS SUBSTANCES (40 CFR 355, APPENDIX A):
Not listed
SECTION 311 HAZARD CATEGORIES (40 CFR 370):
Immediate, Delayed, Fire
SECTION 312 THRESHOLD PLANNING QUANTITY (40 CFR 370):
The Threshold Planning Quantity (TPQ) for this product, if treated as a mixture, is 10,000 lbs;
however, this product contains the following ingredients with a TPQ of less than 10,000 lbs.:
None
SECTION 313 REPORTABLE INGREDIENTS (40 CFR 372):
This product contains the following ingredients subject to Section 313 reporting requirements:
Toluene, Pyridine
CERCLA (COMPREHENSIVE ENVIRONMENTAL RESPONSE COMPENSATION AND
LIABILITY ACT)
CERCLA DESIGNATION & REPORTABLE QUANTITIES (RQ) (40 CFR 302.4):
Listed
Chemical Name RQ
Toluene 1,000 lb
Pyridine 1,000 lb
RESOURCE CONSERVATION AND RECOVERY ACT (RCRA)
RCRA IDENTIFICATION OF HAZARDOUS WASTE (40 CFR 261):
Waste Number: U196, Pyridine
FEDERAL INSECTICIDE FUNGICIDE RODENTICIDE ACT
U.S. EPA Signal Word: WARNING
INTERNATIONAL LISTINGS
Australian Hazard Code: 3XE
HAZARD, RISK AND SAFETY PHRASE DESCRIPTIONS:
Toluene, (Index #601-021-00-3):
Page 9 of 11
SULFENTRAZONE IN TOLUENE (F17-67-4) Date: 11/24/2004
EC Symbols: F (Highly Flammable)
Xn (Harmful)
Xi (Irritant)
EC Risk Phrases: R11 (Highly flammable)
R38 (Irritating to skin)
R48/20 (Harmful: danger of serious damage to health by prolonged
exposure through inhalation)
R63 (Possible risk of harm to the unborn child)
R65 (Harmful: may cause lung damage if swallowed.)
R67 (Vapors may cause drowsiness and dizziness.)
EC Safety Phrases: S2 (Keep out of the reach of children.)
S36/37 (Wear suitable protective clothing and gloves.)
S46 (If swallowed, seek medical advice immediately and show this
container or label.)
S62 (If swallowed, do not induce vomiting: seek medical advice
immediately and show this container or label.)
Pyridine, (Index #613-002-00-7):
EC Symbols: F (Highly Flammable)
Xn (Harmful)
EC Risk Phrases: R11 (Highly flammable)
R20/21/22 (Harmful by inhalation, in contact with skin and if
swallowed.)
EC Safety Phrases: S2 (Keep out of the reach of children.)
S26 (In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice)
S28 (After contact with skin, wash immediately with plenty of water
and soap.)
16. OTHER INFORMATION
EQUIPMENT INVOLVED: R-17100; R17160; T-17161; M-17170
REVISION SUMMARY:
This MSDS replaces Revision #2, dated August 08, 2000.
Changes in information are as follows:
New Format, as well as:
Section 3 (Composition / Information on Ingredients)
Section 11 (Toxicological Information)
Section 14 (Transport Information)
Section 15 (Regulatory Information)
Section 16 (Other Information)
Page 10 of 11
SULFENTRAZONE IN TOLUENE (F17-67-4) Date: 11/24/2004
FMC Logo - FMC Corporation Trademark
Tychem - E.I. du Pont de Nemours & Co Trademark;
Silvershield - North Hand Protection Trademark;
FMC Corporation believes that the information and recommendations contained herein (including data and
statements) are accurate as of the date hereof. NO WARRANTY OF FITNESS FOR ANY PARTICULAR
PURPOSE, WARRANTY OF MERCHANTABILITY, OR ANY OTHER WARRANTY, EXPRESSED
OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED HEREIN. The information
provided herein relates only to the specific product designated and may not be applicable where such
product is used in combination with any other materials or in any process. It is a violation of Federal law to
use this product in a manner inconsistent with its labeling. Further, since the conditions and methods of use
are beyond the control of FMC Corporation, FMC Corporation expressly disclaims any and all liability as
to any results obtained or arising from any use of the product or reliance on such information.
Page 11 of 11
|