SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 03/11/2005
Date Updated: 04/04/2004
Version 1.3
Section 1 - Product and Company Information
Product Name A-KETOGLUTARIC ACID FREE ACID
Product Number K1750
Brand SIGMA
Company Sigma-Aldrich Canada, Ltd
Street Address 2149 Winston Park Drive
City, State, Zip, Country Oakville ON L6H 6J8 CA
Technical Phone: 9058299500
Emergency Phone: 800-424-9300
Fax: 9058299292
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
2-KETOGLUTARIC ACID 328-50-7 No
Formula C5H6O5
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Irritant.
Risk of serious damage to eyes. Irritating to respiratory system
and skin.
HMIS RATING
HEALTH: 2
FLAMMABILITY: 0
REACTIVITY: 0
NFPA RATING
HEALTH: 2
FLAMMABILITY: 0
REACTIVITY: 0
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of contact, immediately wash skin with soap and copious
amounts of water.
EYE EXPOSURE
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
Section 5 - Fire Fighting Measures
FLASH POINT
N/A
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Section 6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not breathe dust. Avoid contact with eyes,
skin, and clothing. Avoid prolonged or repeated exposure.
STORAGE
Suitable: Keep tightly closed.
Store at 2-8掳C
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Government approved respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
Section 9 - Physical/Chemical Properties
Appearance Physical State: Solid
Color: White
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Form: Fine crystals
Property Value At Temperature or Pressure
Molecular Weight 146.1 AMU
pH N/A
BP/BP Range N/A
MP/MP Range 114 掳C
Freezing Point N/A
Vapor Pressure N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
SG/Density N/A
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point N/A
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index N/A
Optical Rotation N/A
Miscellaneous Data N/A
Solubility Solvent: 0.1 g/ml H2O Clear
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Bases, Oxidizing agents, Reducing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation.
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
Section 12 - Ecological Information
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No data available.
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: None
Non-Hazardous for Transport: This substance is
considered to be non-hazardous for transport.
IATA
Non-Hazardous for Air Transport: Non-hazardous for air
transport.
Section 15 - Regulatory Information
EU ADDITIONAL CLASSIFICATION
Symbol of Danger: Xi
Indication of Danger: Irritant.
R: 41 37/38
Risk Statements: Risk of serious damage to eyes. Irritating to
respiratory system and skin.
S: 26 39
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. Wear
eye/face protection.
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Irritant.
Risk Statements: Risk of serious damage to eyes. Irritating to
respiratory system and skin.
Safety Statements: In case of contact with eyes, rinse
immediately with plenty of water and seek medical advice. Wear
suitable protective clothing.
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
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information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
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