Valid 11/2002 - 01/2003



Sigma Chemical Co.

P.O. Box 14508

St. Louis, MO 63178 USA

Phone: 314-771-5765









             MATERIAL         SAFETY       DATA     SHEET



SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -

    CATALOG #:            R4507

    NAME:                 ROSE BENGAL SODIUM

SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -

    CAS #:   632-69-9

    MF: C20H2CL4I4NA2O5

    EC NO: 211-183-3

  SYNONYMS

    FOOD RED COLOR NO. 105, SODIUM SALT * FOOD RED NO. 105, SODIUM SALT *

    ROSE BENGAL SODIUM * R105 SODIUM * 9-(3�,4�,5�,6�-TETRACHLORO-O-) TjETBT/PjCourier 10 T



    7-TETRACHLORO-2�,4�,5�,7�-TETRAIODOFLUORESCEIN DISODIUM SALT *

SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -

  LABEL PRECAUTIONARY STATEMENTS

    CAUTION:

    AVOID CONTACT AND INHALATION.

SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -

    IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.

    CALL A PHYSICIAN.

    IF INHALED, REMOVE TO FRESH AIR. IF BREATHING BECOMES DIFFICULT,

    CALL A PHYSICIAN.

    IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS

    AMOUNTS OF WATER.

    IN CASE OF CONTACT WITH EYES, FLUSH WITH COPIOUS AMOUNTS OF WATER

    FOR AT LEAST 15 MINUTES. ASSURE ADEQUATE FLUSHING BY SEPARATING

    THE EYELIDS WITH FINGERS. CALL A PHYSICIAN.

SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -

  EXTINGUISHING MEDIA

    WATER SPRAY.

    CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.

  SPECIAL FIREFIGHTING PROCEDURES

    WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO

    PREVENT CONTACT WITH SKIN AND EYES.

  UNUSUAL FIRE AND EXPLOSIONS HAZARDS

    EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -

    WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY

    RUBBER GLOVES.

    SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.

    AVOID RAISING DUST.

    VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.

SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -

    REFER TO SECTION 8.

SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -

    SAFETY SHOWER AND EYE BATH.

    MECHANICAL EXHAUST REQUIRED.

    AVOID INHALATION.

    AVOID CONTACT WITH EYES, SKIN AND CLOTHING.

    AVOID PROLONGED OR REPEATED EXPOSURE.

    NIOSH/MSHA-APPROVED RESPIRATOR.

    COMPATIBLE CHEMICAL-RESISTANT GLOVES.

    CHEMICAL SAFETY GOGGLES.

    KEEP TIGHTLY CLOSED.

    STORE IN A COOL DRY PLACE.

    WASH THOROUGHLY AFTER HANDLING.

SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -

    DATA NOT AVAILABLE

SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -

  STABILITY

    STABLE.

  INCOMPATIBILITIES

    STRONG OXIDIZING AGENTS

  HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS

    CARBON MONOXIDE, CARBON DIOXIDE

    HYDROGEN CHLORIDE GAS

    HYDROGEN IODIDE

  HAZARDOUS POLYMERIZATION

    WILL NOT OCCUR.

SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -

  ACUTE EFFECTS

    MAY CAUSE SKIN IRRITATION.

    MAY BE HARMFUL IF ABSORBED THROUGH THE SKIN.

    MAY CAUSE EYE IRRITATION.

    MAY BE HARMFUL IF INHALED.

    MATERIAL MAY BE IRRITATING TO MUCOUS MEMBRANES AND UPPER

    RESPIRATORY TRACT.

    MAY BE HARMFUL IF SWALLOWED.

    TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND

    TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.

  RTECS #: LM5920000

    FLUORESCEIN, 4,5,6,7-TETRACHLORO-2�,4�,5�,7�-TETRAIODO-, DISODIUM SALT

  TARGET ORGAN DATA

    EFFECTS ON EMBRYO OR FETUS (FETOTOXICITY)

    EFFECTS ON NEWBORN (GROWTH STATISTICS)

    ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES

    (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR

    COMPLETE INFORMATION.

SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -

    DATA NOT YET AVAILABLE.

SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -

    DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A

    CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.

    OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.

SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -

    CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.

SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -

  REVIEWS, STANDARDS, AND REGULATIONS

    OEL=MAK

    EPA TSCA SECTION 8(B) CHEMICAL INVENTORY

SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -

    THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO

    BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,

    FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING

    OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR

    PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.

    COPYRIGHT 2001 SIGMA-ALDRICH CO.

    LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY