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MSDS Material Safety Data Sheet
CAS

75-45-6

File Name: arkema-inc_com---435.asp
                                                                      Forane (R) 22
Material Safety Data Sheet
Arkema Inc.
1 PRODUCT AND COMPANY IDENTIFICATION

EMERGENCY PHONE NUMBERS:
DFO
Chemtrec: (800) 424-9300 (24hrs) or (703) 527-3887
2000 Market Street
Medical: Rocky Mountain Poison Control Center
(866) 767-5089 (24Hrs)
Philadelphia, PA 19103
Information Telephone Numbers Phone Number Available Hrs
Product Information 800-245-5858 8:00 am - 5:30 pm (Eastern)

Product Name Forane (R) 22
Product Synonym(s)
R-22, HCFC-22

Chemical Family hydrochlorofluorocarbon
Chemical Formula CHClF2
Chemical Name chlorodifluoromethane
EPA Reg Num
Product Use Refrigerant, foam blowing agent


2 COMPOSITION / INFORMATION ON INGREDIENTS

Ingredient Name CAS RegistryNumber Typical Wt. % OSHA
chlorodifluoromethane (HCFC-22) 75-45-6 100% Y
The substance(s) marked with a "Y" in the OSHA column, are identified as hazardous chemicals according to the
criteria of the OSHA Hazard Communication Standard (29 CFR 1910.1200)

This material is classified as hazardous under Federal OSHA regulation.

The components of this product are all on the TSCA Inventory list.


3 HAZARDS IDENTIFICATION

Emergency Overview
Colorless liquified gas with faint ether odor.
WARNING!
LIQUID AND GAS UNDER PRESSURE, OVERHEATING AND OVERPRESSURIZING MAY CAUSE GAS RELEASE
OR VIOLENT CYLINDER BURSTING. MAY DECOMPOSE ON CONTACT WITH FLAMES OR EXTREMELY HOT
METAL SURFACES TO PRODUCE TOXIC AND CORROSIVE PRODUCTS. VAPOR REDUCES OXYGEN
AVAILABLE FOR BREATHING AND IS HEAVIER THAN AIR. HARMFUL IF INHALED AND MAY CAUSE HEART
IRREGULARITIES, UNCONSCIOUSNESS OR DEATH. LIQUID CONTACT WITH EYES OR SKIN MAY CAUSE
FROSTBITE.

Potential Health Effects

Inhalation and skin contact are expected to be the primary routes of occupational exposure to this material. As with
most liquified gases, contact with the rapidly volatilizing liquid can cause frostbite to any tissue. High vapor
concentrations are irritating to the eyes and respiratory tract and may result in central nervous system (CNS) effects
such as headache, dizziness, drowsiness and, in severe exposure, loss of consciousness and death. The dense vapor
of this material may reduce the available oxygen for breathing. Prolonged exposure to an oxygen-deficient atmosphere
may be fatal. Inhalation may cause an increase in the sensitivity of the heart to adrenaline, which could result in
irregular or rapid heartbeats. Medical conditions aggravated by exposure to this material include heart disease or


Product Code: 04022 Page 1
Revision: 9 Issued: 11 OCT 2004 of 6
Forane (R) 22
Material Safety Data Sheet
Arkema Inc.
compromised heart function.


4 FIRST AID MEASURES

IF IN EYES, immediately flush with plenty of water. Get medical attention if irritation persists.

IF ON SKIN, Flush exposed skin with lukewarm water (not hot), or use other means to warm skin slowly. Get
medical attention if frostbitten by liquid or if irritation occures.

IF SWALLOWED, Not applicable - product is a gas at ambient temperatures.

IF INHALED, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen. Get medical attention. Do not give adrenaline, epinephrin or similar drugs following exposure to this
product.


5 FIRE FIGHTING MEASURES

Fire and Explosive Properties
Auto-Ignition Temperature 632 C (1170 F)
Flash Point NA - GAS Flash Point Method
Flammable Limits- Upper NONE
NONE
Lower
Extinguishing Media
Use extinguishing media appropriate to surrounding fire conditions.
Fire Fighting Instructions
Stop the flow of gas if possible. Use water spray on person making shut-off. Fire fighters and others who may
be exposed to products of combustion should wear full fire fighting turn out gear (full Bunker Gear) and self-
contained breathing apparatus (pressure demand NIOSH approved or equivalent). Fire fighting equipment
should be thoroughly decontaminated after use.
Fire and Explosion Hazards
May decompose on contact with flames or extremely hot metal surfaces to produce toxic and corrosive
products. Liquid and gas under pressure, overheating or overpressurizing may cause gas release and/or violent
cylinder bursting. Container may explode if heated due to resulting pressure rise. Some mixtures of HCFCs
and/or HFCs, and air or oxygen may be combustible if pressurized and exposed to extreme heat or flame.

6 ACCIDENTAL RELEASE MEASURES

In Case of Spill or Leak
Use Halogen leak detector or other suitable means to locate leaks or check atmosphere. Keep upwind.
Evacuate enclosed spaces and disperse gas with floor-level forced-air ventilation. Exhaust vapors outdoors.
Do not smoke or operate internal combustion engines. Remove flames and heating elements.

7 HANDLING AND STORAGE

Handling
Avoid breathing gas. Avoid contact with eyes, skin and clothing. Keep container closed. Use only with
adequate ventilation. Do not enter confined spaces unless adequately ventilated.
Storage
Do not apply direct flame to cylinder. Do not store cylinder in direct sun or expose it to heat above 120 F.


Product Code: 04022 Page 2
Revision: 9 Issued: 11 OCT 2004 of 6
Forane (R) 22
Material Safety Data Sheet
Arkema Inc.

7 HANDLING AND STORAGE

Do not drop or refill this cylinder. Keep away from heat, sparks and flames.



8 EXPOSURE CONTROLS / PERSONAL PROTECTION

Engineering Controls
Investigate engineering techniques to reduce exposures below airborne exposure limits. Provide ventilation
if necessary to control exposure levels below airborne exposure limits (see below). If practical, use local
mechanical exhaust ventilation at sources of air contamination such as open process equipment.
Eye / Face Protection
Where there is potential for eye contact, wear chemical goggles and have eye flushing equipment available.
Skin Protection
Wear appropriate chemical resistant protective clothing and chemical resistant gloves to prevent skin
contact. Consult glove manufacturer to determine appropriate type glove material for given application.
Rinse contaminated skin promptly. Wash contaminated clothing and clean protective equipment before
reuse. Wash skin thoroughly after handling.
Respiratory Protection
Avoid breathing gas. When airborne exposure limits are exceeded (see below), use NIOSH approved
respiratory protection equipment appropriate to the material and/or its components (full facepiece
recommended). Consult respirator manufacturer to determine appropriate type equipment for a given
application. Observe respirator use limitations specified by NIOSH or the manufacturer. For emergency and
other conditions where exposure limit may be significantly exceeded, use an approved full face positive-
pressure, self-contained breathing apparatus or positive-pressure airline with auxiliary self-contained air
supply. Respiratory protection programs must comply with 29 CFR 搂 1910.134.

Airborne Exposure Guidelines for Ingredients
Exposure Limit Value

chlorodifluoromethane (HCFC-22)
ACGIH TWA - 1000 ppm 3540 mg/m3
-Only those components with exposure limits are printed in this section.
-Skin contact limits designated with a "Y" above have skin contact effect. Air sampling alone is insufficient to accurately quantitate
exposure. Measures to prevent significant cutaneous absorption may be required.
-ACGIH Sensitizer designator with a value of "Y" above means that exposure to this material may cause allergic reactions.
-WEEL-AIHA Sensitizer designator with a value of "Y" above means that exposure to this material may cause allergic skin reactions.


9 PHYSICAL AND CHEMICAL PROPERTIES

Colorless liquified gas with faint ether odor.
Appearance/Odor
pH NA
Specific Gravity 1.19 @ 25 C
Vapor Pressure 136 psia @ 21.1 C (70 F)
Vapor Density (AIR = 1) 3.00
Melting Point NE
Freezing Point -160 C (-256 F)
Boiling Point -40.8 C (-41.4 F)
Solubility In Water Slight
Molecular Weight 86.47




Product Code: 04022 Page 3
Revision: 9 Issued: 11 OCT 2004 of 6
Forane (R) 22
Material Safety Data Sheet
Arkema Inc.

10 STABILITY AND REACTIVITY


Stability
This material is chemically stable under specified conditions or storage, shipment and/or use. See
HANDLING AND STORAGE section of this MSDS for specified conditions.
Incompatibility
Avoid contact with strong alkali or alkaline earth metals, finely powdered metals such as aluminum, magnesium
or zinc and strong oxidizers, since they may react or accelerate decomposition.
Hazardous Decomposition Products
Thermal decomposition products could include Halogen acids (HCl and HF), Halogens, Carbon monoxide,
Carbon dioxide, and Carbonyl halides.

11 TOXICOLOGICAL INFORMATION

Toxicological Information
Single exposure (acute) studies indicate:
Inhalation - Practically Non-toxic to Rats (2 hr-LC50 300,000 ppm)
Eye Irritation - Slightly Irritating to Rabbits (5-30 sec. exposure to gas spray)
Skin Irritation - Moderately Irritating to Rabbits (liquefied gas with patch applied) Several accidental deaths have
been associated with exposure to this material or mixtures with other fluorocarbons. Death was generally
attributed to oxygen deficiency. Microscopic examination of the tissues of some of the victims showed effects
on the lungs and fatty deposits in liver cells. An increase in the incidence of heart palpitations has been claimed
by individuals occupationally exposed. Monitoring of workers during occupational exposure showed no
connection to exposure and cardiac arrhythmia or neurologic disorders. Other epidemiological studies have
reported similar results. Repeated skin application of a 10 second spray caused reddening and slight swelling
of the skin and a delay in hair growth.

No skin allergy was observed in guinea pigs following repeated exposure. Studies with mice, dogs, rats, rabbits,
cats and monkeys have shown that inhalation exposure can cause cardiac arrhythmias. Inhalation causes an
initial stimulation and then depression of the central nervous system (CNS). Symptoms in animals include loss
of equilibrium, tremors, convulsions and narcosis and death, usually attributed to asphyxiation. At levels that
caused anesthesia, dogs exhibited convulsions. Acute exposure by inhalation was fatal to rabbits, also causing
hemorrhages and effects on the liver. Following repeated inhalation exposure, no effects were reported in
guinea pigs, dogs and cats; mild liver effects were reported in rabbits; and, effects on the lungs, CNS, heart,
liver, kidney, spleen were reported in rats, mice and rabbits. An increase in malignant tumors of the salivary
glands was reported in male rats but not in female rats or mice of either sex after long-term inhalation exposure.
Long-term oral dosing produced no adverse effects in rats. Inhalation exposure produced no adverse effects
on male reproductive performance in rats and mice. Eye malformations were reported in the offspring of rats
exposed by inhalation during pregnancy. In rabbits, rats and humans, a small portion of inhaled material was
distributed into the brain, heart, lungs, liver, kidneys and fat. It was rapidly eliminated from the body in the
inhaled air. No significant metabolism occurs in humans or rats. The results of the tests for genetic changes
were mixed.

12 ECOLOGICAL INFORMATION

Ecotoxicological Information
The toxicity threshold for fish is 180 mg/l (24-hrs) and for bacteria under anaerobic conditions is >400 mg/l (24-
hrs). No effects were reported on the growth of aerobic and anaerobic microorganisms over a 24 hour period,
including gram-positive and gram-negative species, from exposure to a media that contained this material at 5
mg/ml.




Product Code: 04022 Page 4
Revision: 9 Issued: 11 OCT 2004 of 6
Forane (R) 22
Material Safety Data Sheet
Arkema Inc.

12 ECOLOGICAL INFORMATION

Chemical Fate Information
Chlorodifluoromethane
This material is not readily biodegradable (0% after 28-days) and is practically not bioaccumulable (log Pow
1.08). In air, it has a half-life in the atmosphere of 8.4 years, an ozone depletion potential (ODP) of 0.055, and a
halocarbon global warming potential (HGWP) of 0.33. It is moderately adsorbed in soils and sediments (log Koc
1.8).

13 DISPOSAL CONSIDERATIONS

Waste Disposal
Recover, reclaim or recycle when practical. Dispose of in accordance with federal, state and local regulations.
Note: Chemical additions to, processing of, or otherwise altering this material may make this waste
management information incomplete, inaccurate, or otherwise inappropriate. Furthermore, state and local
waste disposal requirements may be more restrictive or otherwise different from federal laws and regulations.

14 TRANSPORT INFORMATION

DOT Name Chlorodifluoromethane
DOT Technical Name
DOT Hazard Class 2.2
UN Number UN 1018
DOT Packing Group PG NA
RQ



15 REGULATORY INFORMATION

Hazard Categories Under Criteria of SARA Title III Rules (40 CFR Part 370)
Immediate (Acute) Health Y Fire N
Reactive
Delayed (Chronic) Health N N
Sudden Release of Pressure Y
The components of this product are all on the TSCA Inventory list.


Ingredient Related Regulatory Information:
CERCLA RQ SARA TPQ
SARA Reportable Quantities
chlorodifluoromethane (HCFC-22) NE

SARA Title III, Section 313
This product does contain chemical(s) which are defined as toxic chemicals under and subject to the reporting requirements of, Section
313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 and 40 CFR Part 372. See Section 2
chlorodifluoromethane (HCFC-22)

Massachusetts Right to Know
This product does contain the following chemicals(s), as indicated below, currently on the Massachusetts Right to Know Substance
List.
chlorodifluoromethane (HCFC-22)
New Jersey Right to Know
This product does contain the following chemical(s), as indicated below, currently on the New Jersey Right-to-Know Substances List.


Product Code: 04022 Page 5
Revision: 9 Issued: 11 OCT 2004 of 6
Forane (R) 22
Material Safety Data Sheet
Arkema Inc.

New Jersey Right to Know
This product does contain the following chemical(s), as indicated below, currently on the New Jersey Right-to-Know Substances List.
chlorodifluoromethane (HCFC-22)
Pennsylvania Environmental Hazard
This product does contain the following chemical(s), as indicated below, currently on the Pennsylvania Environmental Hazard List.
chlorodifluoromethane (HCFC-22)
Pennsylvania Right to Know
This product does contain the following chemical(s), as indicated below, currently on the Pennsylvania Hazardous Substance List.
chlorodifluoromethane (HCFC-22)

16 OTHER INFORMATION


Revision Information

Revision Number 9
11 OCT 2004
Revision Date
Supercedes Revision Dated 18-FEB-2004
Revision Summary
ATOFINA Chemicals, Inc. has changed its name to Arkema Inc..

Key
NE= Not Established NA= Not Applicable (R) = Registered Trademark




Arkema Inc. believes that the information and recommendations contained herein (including data and
statements) are accurate as of the date hereof. NO WARRANTY OF FITNESS FOR ANY PARTICULAR
PURPOSE, WARRANTY OF MERCHANTABILITY, OR ANY OTHER WARRANTY, EXPRESSED OR
IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED HEREIN. The information provided
herein relates only to the specific product designated and may not be valid where such product is used in
combination with any other materials or in any process. Further, since the conditions and methods of use are
beyond the control of Arkema Inc., Arkema Inc. expressly disclaims any and all liability as to any results
obtained or arising from any use of the product or reliance on such information.




Product Code: 04022 Page 6
Revision: 9 Issued: 11 OCT 2004 of 6

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