REAGENTS, INC.--MSDS--IMIDAZOLE PAGE -1-
IMIDAZOLE
1. Chemical Product And Company Identification
Company's Name: REAGENTS, INC.
Company's P. O. Box: 240746
Company's City: CHARLOTTE
Company's State: NC
Company's Country: US
Company's Zip Code: 28224
Company's Info Ph #: 704/554-7474, 800/732-8484
Emergencies, call CHEMTREC: 800-424-9300
Date MSDS Prepared: April 25, 2003
Synonyms: Glyoxaline; Iminazole
CAS No.: 288-32-4
Molecular Weight: 68.08
Chemical Formula: C3H4N2
Product Codes: 2-21660
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Imidazole 288-32-4 90 - 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
DANGER! CORROSIVE. CAUSES BURNS TO ANY AREA OF CONTACT. HARMFUL IF
SWALLOWED OR INHALED.
-----------------------------------------------------------------------------------------------------------
Health Rating: 2 - Moderate
Flammability Rating: 1 - Slight
Reactivity Rating: 1 - Slight
Contact Rating: 3 - Severe (Corrosive)
Lab Protective Equip: GOGGLES; LAB COAT
Storage Color Code: White (Corrosive)
-----------------------------------------------------------------------------------------------------------
Potential Health Effects
----------------------------------
Information on the human health effects from exposure to this substance is limited.
Inhalation: Extremely destructive to tissues of the mucous membranes and upper respiratory tract.
REAGENTS, INC.--MSDS--IMIDAZOLE PAGE -2-
Symptoms may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache,
nausea and vomiting.
Ingestion: Corrosive. Swallowing can cause severe burns of the mouth, throat, and stomach, leading to
death. Can cause sore throat, vomiting, diarrhea.
Skin Contact: Corrosive. Symptoms of redness, pain, and severe burn can occur.
Eye Contact: Corrosive. Can cause blurred vision, redness, pain, severe tissue burns and eye damage.
Can cause blindness.
Chronic Exposure: Chronic exposure may cause respiratory system effects. Chronic exposure may
cause skin effects.
Aggravation of Pre-existing Conditions: Persons with pre-existing skin disorders or eye problems or
impaired respiratory function may be more susceptible to the effects of the substance.
4. First Aid Measures
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen. Get medical attention immediately.
Ingestion: If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give
anything by mouth to an unconscious person. Get medical attention immediately.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical attention immediately. Wash clothing before reuse.
Thoroughly clean shoes before reuse. DO NOT APPLY GREASES OR OINTMENTS!
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper
eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Fire: Flash point: 146oC (295oF) CC
Explosion: Above the flash point, explosive vapor-air mixtures may be formed.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-
contained breathing apparatus with full-facepiece operated in the pressure demand or other positive
pressure mode.
6. Accidental Release Measures
Remove all sources of ignition. Ventilate area of leak or spill. Wear appropriate personal protective
equipment as specified in Section 8. Spills: Clean up spills in a manner that does not disperse dust into
the air. Use non-sparking tools and equipment. Reduce airborne dust and prevent scattering by
moistening with water. Pick up spill for recovery or disposal and place in a closed container.
7. Handling and Storage
Keep in a tightly closed container. Store in a cool, dry, ventilated area away from sources of heat or
ignition. Protect against physical damage. Store separately from reactive or combustible materials, and
REAGENTS, INC.--MSDS--IMIDAZOLE PAGE -3-
out of direct sunlight. Isolate from incompatible substances. Containers of this material may be
hazardous when empty since they retain product residues (dust, solids); observe all warnings and
precautions listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee
exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the
emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please
refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent
edition, for details.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the dust or mist is
apparent, a half-face dust/mist respirator may be worn. For emergencies or instances where the
exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-
purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or
coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of
solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance: White flakes.
Odor: No information found.
Solubility: Soluble in water.
Specific Gravity: 0.60
pH: No information found.
% Volatiles by volume @ 21oC (70oF): 0
Boiling Point: 256oC (493oF)
Melting Point: 89 鈥? 91oC (192 鈥? 196oF)
Vapor Density (Air=1): No information found.
Vapor Pressure (mm Hg): No information found.
Evaporation Rate (BuAc=1): No information found.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Burning may produce carbon monoxide, carbon dioxide, nitrogen
oxides.
Hazardous Polymerization: This substance does not polymerize.
Incompatibilities: Strong oxidizers.
Conditions to Avoid: Heat, flames, ignition sources and incompatibles.
REAGENTS, INC.--MSDS--IMIDAZOLE PAGE -4-
11. Toxicological Information
Oral rat LD50: 220 mg/Kg. Investigated as a mutagen, reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- ------------
Imidazole (288-32-4) No No None
12. Ecological Information
Environmental Fate: No information found.
Environmental Toxicity: No information found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved
waste disposal facility. Processing, use or contamination of this product may change the waste
management options. State and local disposal regulations may differ from federal disposal regulations.
Dispose of container and unused contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: CORROSIVE SOLID, BASIC, ORGANIC, N.O.S. (IMIDAZOLE)
Hazard Class: 8
UN/NA: UN3263
Packing Group: III
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: CORROSIVE SOLID, BASIC, ORGANIC, N.O.S. (IMIDAZOLE)
Hazard Class: 8
UN/NA: UN3263
Packing Group: III
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
REAGENTS, INC.--MSDS--IMIDAZOLE PAGE -5-
----------------------------------------------- ---- --- ----- ---------
Imidazole (288-32-4) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Imidazole (288-32-4) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Imidazole (288-32-4) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Imidazole (288-32-4) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No
Reactivity: No (Pure / Solid)
WHMIS: This MSDS has been prepared according to the hazard criteria of the Controlled Products
Regulations (CPR) and the MSDS contains all of the information required by the CPR.
16. Other Information
NFPA Ratings: Health: 3 Flammability: 1 Reactivity: 0
Label Hazard Warning: DANGER! CORROSIVE. CAUSES BURNS TO ANY AREA OF CONTACT.
HARMFUL IF SWALLOWED OR INHALED.
Label Precautions: Do not get in eyes, on skin, or on clothing.
Wash thoroughly after handling. Do not breathe dust.
Use only with adequate ventilation. Keep container closed.
Label First Aid: In case of contact, immediately flush eyes or skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing before reuse. If inhaled,
remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If
swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by
mouth to an unconscious person. In all cases get medical attention immediately.
Product Use: Laboratory Reagent.
Disclaimer:
************************************************************************************
Reagents, Inc. provides the information contained herein in good faith but makes no representation
as to its comprehensiveness or accuracy. This document is intended only as a guide to the
appropriate precautionary handling of the material by a properly trained person using this product.
REAGENTS, INC.--MSDS--IMIDAZOLE PAGE -6-
Individuals receiving the information must exercise their independent judgment in determining its
appropriateness for a particular purpose. REAGENTS, INC. MAKES NO REPRESENTATIONS
OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION
ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE
WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO
WHICH THE INFORMATION REFERS. ACCORDINGLY, REAGENTS, INC. WILL NOT BE
RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
************************************************************************************
|