REAGENTS, INC.--MSDS--METHYL ETHYL KETONE                                                       PAGE -1-







                                METHYL ETHYL KETONE



1. Chemical Product And Company Identification

Company's Name: REAGENTS, INC.

Company's P. O. Box: 240746

Company's City: CHARLOTTE

Company's State: NC

Company's Country: US

Company's Zip Code: 28224

Company's Info Ph #: 704/554-7474, 800/732-8484

Emergencies, call CHEMTREC: 800-424-9300

Date MSDS Prepared: April 25, 2003

Synonyms: 2-Butanone; ethyl methyl ketone; MEK; Methyl acetone

CAS No.: 78-93-3

Molecular Weight: 72.11

Chemical Formula: CH3COCH2CH3

Product Codes: 1-25050, 2-25050



2. Composition/Information on Ingredients

Ingredient                                  CAS No      Percent    Hazardous

--------------------------------------- ------------   -------     ---------

Methyl Ethyl Ketone                        78-93-3     99 - 100%        Yes



3. Hazards Identification

Emergency Overview

--------------------------

DANGER! EXTREMELY FLAMMABLE LIQUID AND VAPOR. VAPOR MA Y CAUSE FLASH

FIRE. HARMFUL OR FATAL IF SWALLOWED. HARMFUL IF INHALED OR ABSORBED

THROUGH SKIN. AFFECTS CENTRAL NERVOUS SYSTEM. CAUSES IRRITATION TO

SKIN, EYES AND RESPIRATORY TRACT.

-----------------------------------------------------------------------------------------------------------

Health Rating: 2 - Moderate

Flammability Rating: 4 - Extreme (Flammable)

Reactivity Rating: 2 - Moderate

Contact Rating: 2 - Moderate

Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES; CLASS B

EXTINGUISHER

Storage Color Code: Red (Flammable)

-----------------------------------------------------------------------------------------------------------

REAGENTS, INC.--MSDS--METHYL ETHYL KETONE                                                     PAGE -2-





Potential Health Effects

----------------------------------

Inhalation: Causes irritation to the nose and throat. Concentrations above the TLV may cause

headache, dizziness, nausea, shortness of breath, and vomiting. Higher concentrations may cause

central nervous system depression and unconsciousness.

Ingestion: May produce abdominal pain, nausea. Aspiration into lungs can produce severe lung

damage and is a medical emergency. Other symptoms expected to parallel inhalation.

Skin Contact: Causes irritation to skin. Symptoms include redness, itching, and pain. May be absorbed

through the skin with possible systemic effects.

Eye Contact: Vapors are irritating to the eyes. Splashes can produce painful irritation and eye damage.

Chronic Exposure: Prolonged skin contact may defat the skin and produce dermatitis. Chronic

exposure may cause central nervous system effects.

Aggravation of Pre-existing Conditions: Persons with pre-existing skin disorders or eye problems or

impaired respiratory function may be more susceptible to the effects of the substance.



4. First Aid Measures

Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult,

give oxygen. Get medical attention.

Ingestion: Aspiration hazard. If swallowed, vomiting may occur spontaneously, but DO NOT INDUCE.

If vomiting occurs, keep head below hips to prevent aspiration into lungs. Never give anything by

mouth to an unconscious person. Call a physician immediately.

Skin Contact: Immediately flush skin with plenty of soap and water for at least 15 minutes while

removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse.

Thoroughly clean shoes before reuse.

Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and

lower eyelids occasionally.Get medical attention.



5. Fire Fighting Measures

Fire: Flash point: -9oC (16oF) CC

Autoignition temperature: 404oC (759oF)

Flammable limits in air % by volume: lel: 1.4; uel: 11.4

Extremely Flammable.

Explosion: Above flash point, vapor-air mixtures are explosive within flammable limits noted above.

Vapors can flow along surfaces to distant ignition source and flash back. Contact with strong oxidizers

may cause fire. Sealed containers may rupture when heated. Sensitive to static discharge.

Fire Extinguishing Media: Dry chemical, foam or carbon dioxide. Water spray may be used to keep

fire exposed containers cool, dilute spills to nonflammable mixtures, protect personnel attempting to

stop leak and disperse vapors.

Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-

contained breathing apparatus with full-facepiece operated in the pressure demand or other positive

pressure mode. This highly flammable liquid must be kept from sparks, open flame, hot surfaces, and

all sources of heat and ignition.

REAGENTS, INC.--MSDS--METHYL ETHYL KETONE                                                      PAGE -3-









6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective

equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel

from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment.

Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand,

earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust.

Do not flush to sewer! If a leak or spill has not ignited, use water spray to disperse the vapors, to

protect personnel attempting to stop leak, and to flush spills away from exposures. US Regulations

(CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities.

The toll free number for the US Coast Guard National Response Center is (800) 424-8802.





7. Handling and Storage

Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area

where the fire hazard may be acute. Outside or detached storage is preferred. Separate from

incompatibles. Containers should be bonded and grounded for transfers to avoid static sparks. Storage

and use areas should be No Smoking areas. Use non-sparking type tools and equipment, including

explosion proof ventilation. Containers of this material may be hazardous when empty since they retain

product residues (vapors, liquid); observe all warnings and precautions listed for the product.



8. Exposure Controls/Personal Protection

Airborne Exposure Limits:

-OSHA Permissible Exposure Limit (PEL):

200 ppm (TWA)

-ACGIH Threshold Limit Value (TLV):

200 ppm (TWA), 300 ppm (STEL)



Ventilation System: A system of local and/or general exhaust is recommended to keep employee

exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred

because it can control the emissions of the contaminant at its source, preventing dispersion of it into

the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of

Recommended Practices, most recent edition, for details. Use explosion-proof equipment.

Personal Respirators (NIOSH Approved): If the exposure limit is exceeded, a full-facepiece respirator

with organic vapor cartridge may be worn up to 50 times the exposure limit or the maximum use

concentration specified by the appropriate regulatory agency or respirator supplier, whichever is

lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece

positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers

REAGENTS, INC.--MSDS--METHYL ETHYL KETONE                                                     PAGE -4-





in oxygen-deficient atmospheres.

Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or

coveralls, as appropriate, to prevent skin contact. Butyl rubber is a suitable material for personal

protective equipment.

Eye Protection: Use chemical safety goggles and/or a full face shield where splashing is possible.

Maintain eye wash fountain and quick-drench facilities in work area.





9. Physical and Chemical Properties

Appearance: Clear, colorless liquid.

Odor: Sharp mint-like odor.

Solubility: 29 g in 100 g of water.

Specific Gravity: 0.81 @ 20oC/4oC

pH: No information found.

% Volatiles by volume @ 21oC (70oF): 100

Boiling Point: 80oC (176oF)

Melting Point: -86oC (-123oF)

Vapor Density (Air=1): 2.5

Vapor Pressure (mm Hg): 78 @ 20oC (68oF)

Evaporation Rate (BuAc=1): 2.7 (Ether = 1)



10. Stability and Reactivity

Stability: Stable under ordinary conditions of use and storage.

Hazardous Decomposition Products: Carbon dioxide and carbon monoxide may form when heated to

decomposition.

Hazardous Polymerization: Will not occur.

Incompatibilities: Oxidizing materials, caustics, amines, ammonia, strong bases, chloroform,

chlorosulfonic acid, oleum, potassium-t-butoxide, heat or flame, hydrogen peroxide, nitric acid. Can

attack many plastics, resins and rubber.

Conditions to Avoid: Heat, flames, ignition sources and incompatibles.



11. Toxicological Information

Toxicological Data: Oral rat LD50: 2737 mg/kg; inhalation rat LC50: 23,500 mg/m3/8-hr; skin rabbit

LD50: 6480 mg/kg; investigated as a mutagen, reproductive effector.

Reproductive Toxicity: Has shown teratogenic effects in laboratory animals.



--------\Cancer Lists\------------------------------------------------------

                                            ---NTP Carcinogen---

Ingredient                                  Known Anticipated IARC Category

------------------------------------        -----       -----------        -------------

Methyl Ethyl Ketone (78-93-3)                  No             No                  None

REAGENTS, INC.--MSDS--METHYL ETHYL KETONE                                                     PAGE -5-





12. Ecological Information

Environmental Fate: When released into the soil, this material may leach into groundwater. When

released into the soil, this material may evaporate to a moderate extent. When released into water, this

material may biodegrade to a moderate extent. When released into water, this material may evaporate

to a moderate extent. When released into water, this material is expected to have a half-life between 10

and 30 days. This material is not expected to significantly bioaccumulate. When released into the air,

this material is expected to be readily degraded by reaction with photochemically produced hydroxyl

radicals. When released into the air, this material is expected to have a half-life between 1 and 10 days.

Environmental Toxicity: This material is not expected to be toxic to aquatic life. The LC50/96-hour

values for fish are over 100 mg/l.



13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to

a RCRA-approved incinerator or disposed in a RCRA-approved waste facility. Processing, use or

contamination of this product may change the waste management options. State and local disposal

regulations may differ from federal disposal regulations. Dispose of container and unused contents in

accordance with federal, state and local requirements.



14. Transport Information

Domestic (Land, D.O.T.)

-----------------------

Proper Shipping Name: ETHYL METHYL KETONE

Hazard Class: 3

UN/NA: UN1193

Packing Group: II



International (Water, I.M.O.)

-----------------------------

Proper Shipping Name: ETHYL METHYL KETONE

Hazard Class: 3.2

UN/NA: UN1193

Packing Group: II



15. Regulatory Information

--------\Chemical Inventory Status - Part 1\---------------------------------

Ingredient                                       TSCA EC Japan Australia

----------------------------------------------- ---- --- ----- ---------

Methyl Ethyl Ketone (78-93-3)                     Yes Yes Yes       Yes



--------\Chemical Inventory Status - Part 2\---------------------------------

REAGENTS, INC.--MSDS--METHYL ETHYL KETONE                                                        PAGE -6-





                                                            --Canada--

Ingredient                                        Korea DSL NDSL Phil.

-----------------------------------------------   ----- ---     ---- -----

Methyl Ethyl Ketone (78-93-3)                        Yes Yes       No Yes



--------\Federal, State & International Regulations - Part 1\----------------

                                           -SARA 302- ------SARA 313------

Ingredient                                 RQ TPQ List Chemical Catg.

----------------------------------------- --- ----- ---- --------------

Methyl Ethyl Ketone (78-93-3)               No No     Yes        No



--------\Federal, State & International Regulations - Part 2\----------------

                                                   -RCRA- -TSCA-

Ingredient                                CERCLA 261.33 8(d)

-----------------------------------------  ------ ------   ------

Methyl Ethyl Ketone (78-93-3)               5000    U159      No



Chemical Weapons Convention: No TSCA 12(b): No CDTA: Yes

SARA 311/312: Acute: Yes Chronic: Yes        Fire: Yes Pressure: No

Reactivity: No     (Pure / Liquid)

WHMIS: This MSDS has been prepared according to the hazard criteria of the Controlled Products

Regulations (CPR) and the MSDS contains all of the information required by the CPR.



16. Other Information

NFPA Ratings: Health: 3 Flammability: 3 Reactivity: 0

Label Hazard Warning: DANGER! EXTREMELY FLAMMABLE LIQUID AND VAPOR. VAPOR MAY

CAUSE FLASH FIRE. HARMFUL OR FATAL IF SWALLOWED. HARMFUL IF INHALED OR

ABSORBED THROUGH SKIN. AFFECTS CENTRAL NERVOUS SYSTEM. CAUSES IRRITATION TO

SKIN, EYES AND RESPIRATORY TRACT.

Label Precautions: Keep away from heat, sparks and flame. Keep container closed.

Use only with adequate ventilation. Wash thoroughly after handling.

Avoid breathing vapor. Avoid contact with eyes, skin and clothing.

Label First Aid: Aspiration hazard. If swallowed, vomiting may occur spontaneously, but DO NOT

INDUCE. If vomiting occurs, keep head below hips to prevent aspiration into lungs. Never give

anything by mouth to an unconscious person. In case of contact, immediately flush eyes or skin with

plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing

before reuse. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is

difficult, give oxygen. In all cases, get medical attention.

Product Use: Laboratory Reagent.

Disclaimer:

***********************************************************************************

Reagents, Inc. provides the information contained herein in good faith but makes no representation

as to its comprehensiveness or accuracy. This document is intended only as a guide to the

appropriate precautionary handling of the material by a properly trained person using this product.

REAGENTS, INC.--MSDS--METHYL ETHYL KETONE                                             PAGE -7-





Individuals receiving the information must exercise their independent judgment in determining its

appropriateness for a particular purpose. REAGENTS, INC. MAKES NO REPRESENTATIONS

OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION

ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE

WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO

WHICH THE INFORMATION REFERS. ACCORDINGLY, REAGENTS, INC. WILL NOT BE

RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS

INFORMATION.

***********************************************************************************