MATERIAL SAFETY DATA SHEET
CONTROL SOLUTIONS, INC. TRANSPORTATION EMERGENCY
5903 Genoa-Red Bluff CALL CHEMTREC: 800-424-9300
Pasadena, TX 77507 INTERNATIONAL: 703-527-3887
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1. CHEMICAL PRODUCT IDENTIFICATION:
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PRODUCT NAME ....... : Martin鈥檚 Dominion Tree & Shrub (EPA Reg. No. 53883-205)
CHEMICAL FAMILY .... : Chloronicotinyl
CHEMICAL NAME ...... : 1- ( (6-chloro-3-pyridinyl)methyl)-N-nitro
-2-imidazolidinimine
SYNONYMS ............ : Imidacloprid
FORMULA ............. : C9 H10 Cl N5 O2
PRODUCT USE ........ : Consumer Insecticide
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2. COMPOSITION/INFORMATION ON INGREDIENTS:
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INGREDIENT NAME
/CAS NUMBER EXPOSURE LIMITS CONCENTRATION (%)
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***** HAZARDOUS INGREDIENTS *****
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Imidacloprid
138261-41-3 OSHA : Not Established 1.47 %
ACGIH: Not Established
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3. HAZARDS IDENTIFICATION:
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EMERGENCY OVERVIEW
*
鈭? CAUTION! Color: Tan; Form: Liquid; Opaque aqueous
鈭? suspension; Odor: Similar to white glue; Causes eye
鈭? irritation.
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3. HAZARDS IDENTIFICATION (Continued)
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POTENTIAL HEALTH EFFECTS:
ROUTE(S) OF ENTRY: Inhalation; Skin Contact; Eye Contact; Ingestion
HUMAN EFFECTS AND SYMPTOMS OF OVEREXPOSURE:
ACUTE EFFECTS OF EXPOSURE : Exposure during the labeled use of this product is
expected to be minimal. Consumers should refer to the packaging label for
proper handling procedures. No specific symptoms of acute overexposure are
known to occur in humans. Based on EPA Toxicity Category criteria, this
product is mildly toxic by the oral and dermal routes of exposure. In
addition, animal studies have shown that it is minimally irritating to the
conjunctiva of the eye but the irritation is reversible within 72 hours.
CHRONIC EFFECTS OF EXPOSURE: Based on animal studies, no adverse effects are
expected from chronic exposure to this product.
CARCINOGENICITY : This product is not listed by NTP, IARC or regulated as a
carcinogen by OSHA.
MEDICAL CONDITIONS
AGGRAVATED BY EXPOSURE : No specific medical conditions are known which may
be aggravated by exposure to this product.
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4. FIRST AID MEASURES:
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FIRST AID FOR EYES : Hold eye open and rinse slowly and gently with water for
15-20 minutes. Remove contact lenses, if present, after the first 5
minutes, then continue rinsing eye. Call a poison control center or doctor
for treatment advice.
FIRST AID FOR SKIN : Take off contaminated clothing. Rinse skin immediately
with plenty of water for 15-20 minutes. Call a poison control center or
doctor for treatment advice.
FIRST AID FOR INHALATION: Move person to fresh air. If person is not
breathing, call 911 or an ambulance, then give artificial respiration,
preferably by mouth-to-mouth, if possible. Call a poison control center or
doctor for further treatment information.
FIRST AID FOR INGESTION.: Call poison control center or doctor immediately for
treatment advice. Have person sip a glass of water if able to swallow. Do
not induce vomiting unless told to do so by physician or poison control
center. Do not give anything by mouth to an unconscious person.
NOTE TO PHYSICIAN : Treat symptomatically.
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5. FIRE FIGHTING MEASURES:
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FLASH POINT : Greater than 200 F (93 C)
EXTINGUISHING MEDIA : Water; Carbon Dioxide; Dry Chemical; Foam
SPECIAL FIRE FIGHTING PROCEDURES: Keep out of smoke, cool exposed containers
with water spray. Fight fire from upwind position. Use self-contained
breathing equipment. Contain run-off by diking to prevent entry into
sewers or waterways. Equipment or materials involved in pesticide fires
may become contaminated.
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6. ACCIDENTAL RELEASE MEASURES:
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SPILL OR LEAK PROCEDURES : Isolate area and keep unauthorized people away. Do
not walk through spilled material. Avoid breathing vapors and skin
contact. Remove sources of ignition if combustible or flammable vapors may
be present and ventilate area. Wear proper protective equipment. Dike
contaminated area with absorbent granules, soil, sand, etc. If large
spill, material should be recovered. Small spills can be absorbed with
absorbent granules, spill control pads, or any absorbent material.
Carefully sweep up absorbed spilled material. Place in covered container
for reuse or disposal. Scrub contaminated area with soap and water. Use
dry absorbent material such as clay granules to absorb and collect wash
solution for proper disposal. Contaminated soil may have to be removed and
disposed. Do not allow material to enter streams, sewers, or other
waterways or contact vegetation.
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7. HANDLING AND STORAGE:
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STORAGE TEMPERATURE (MIN/MAX): 32 F/30 day avg. not to exceed 100 F (38 C)
SHELF LIFE : Time/temperature dependent. Contact Bayer for additional
information.
SPECIAL SENSITIVITY : Not established
HANDLING/STORAGE PRECAUTIONS: Do not allow product to contaminate material
which is intended for use or consumption by humans or animals.
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8. PERSONAL PROTECTION:
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REQUIRED WORK/HYGIENE PROCEDURES: Exposure during the labeled use of this
product is expected to be minimal. Consumers should refer to the packaging
label for proper handling procedures. However, if exposure to this product is
possible while handling large quantities such as in subsequent
manufacturing, transportation spills or other emergencies, the following
personal protection is recommended.
EYE PROTECTION REQUIREMENTS : Splash-proof goggles
SKIN PROTECTION REQUIREMENTS : Long sleeves and trousers
HAND PROTECTION REQUIREMENTS : Chemical-resistant gloves such as latex or
nitrile
VENTILATION REQUIREMENTS : Control exposure levels through the use of general
and local exhaust ventilation where needed.
RESPIRATOR REQUIREMENTS : If needed, based on the conditions of use, wear a
NIOSH-approved particulate respirator.
ADDITIONAL PROTECTIVE MEASURES : Clean water should be available for
washing in case of eye or skin contamination. Educate and train employees
in safe use of the product. Follow all label instructions. Launder
clothing after use. Wash thoroughly after handling.
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9. PHYSICAL AND CHEMICAL PROPERTIES:
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: Liquid
PHYSICAL FORM ................
: Opaque aqueous suspension
APPEARANCE .....................
: Tan
COLOR ............................
: Similar to white glue
ODOR ..............................
: 255.7 (for imidacloprid)
MOLECULAR WEIGHT ............
: 7.3-8.3
pH ................................
: Not established
BOILING POINT ................
: Freezing: 32 F (0 C)
MELTING/FREEZING POINT ....
: approx. 300 cps @ 20 C
VISCOSITY ......................
: 0.51 g/L @ 20 C (for imidacloprid)
SOLUBILITY IN WATER .......
: 1.06 @ 20 C/20 C
SPECIFIC GRAVITY ............
: Not applicable
BULK DENSITY ..................
: 1.5 x 10-9 mm @ 20 C (for imidacloprid)
VAPOR PRESSURE ...............
10. STABILITY AND REACTIVITY:
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STABILITY : This is a stable material. HAZARDOUS
POLYMERIZATION: Will not occur.
INCOMPATIBILITIES : None known
INSTABILITY CONDITIONS : Strong exothermal reaction above 200 C
(imidacloprid)
DECOMPOSITION PRODUCTS : Proposed under extreme conditions such as fire: HCl,
HCN, CO, NO(x) (for imidacloprid)
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11. TOXICOLOGICAL INFORMATION:
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Acute toxicology studies have not been performed on this product as formulated.
The acute toxicology information provided are from a similar formulation
containing a higher percentage of the active ingredient, imidacloprid. The non-
acute information pertains to imidacloprid technical.
ACUTE TOXICITY
ORAL LD50: Male Rat: >4870 mg/kg; Female rat: 4143 mg/kg
DERMAL LD50: Male and Female Rabbit: >2000 mg/kg
INHALATION LC50: 4 Hr Exposure to Liquid Aerosol: Male and Female Rat: >5.33
mg/L (analytical); 1 Hr Exposure to Liquid Aerosol (extrapolated from 4 Hr
LC50):Male and Female Rat: >20 mg/L (analytical)
EYE EFFECTS : Rabbit: Only minimal irritation to the conjunctiva was observed
with all irritation resolving within 72 hours.
SKIN EFFECTS : Rabbit: Not a dermal irritant.
SENSITIZATION : Guinea Pig: Not a dermal sensitizer.
SUBCHRONIC TOXICITY: In a 3 week dermal toxicity study, rabbits were treated
with the active ingredient, imidacloprid, at the limit dose level of 1000 mg/kg
for 6 hours/day, 5 days/week. There were no local or systemic effects observed
at any of the levels tested. The no-observed-effect-level (NOEL) was 1000 mg/kg.
In a 4 week inhalation study, rats were exposed to dust concentrations of
imidacloprid at 5.5, 30.5 and 191.2 mg/cubic meter for 6 hours/day, 5
days/week. Effects observed at the high concentration included decreased body
weight gains, decreased heart and thymus weights, increased liver weights, and
induction of the hepatic mixed-function oxidases. Histopathological
examinations did not reveal any organ damage or local injury to the respiratory
tract. The NOEL was 5.5 mg/cubic meter based on induction of the hepatic mixed-
functioned oxidases.
CHRONIC TOXICITY : Dogs were administered imidacloprid for 1 year at dietary
concentrations of 200, 500 or 1250 ppm. Due to the lack of significant effects,
the high dose was increased to 2500 ppm at 17 weeks for the remainder of the
study. Effects observed at the high dose included decreased food consumption,
increased liver weights and elevated serum chemistries. The NOEL was 500 ppm.
In chronic studies using rats, imidacloprid was administered for 2 years at
dietary concentrations of 100,300, 900 or 1800 ppm. Histopathology examinations
revealed an increased incidence of mineralization in the colloid of the thyroid
follicles at concentrations of 300 ppm and greater. At 1800 ppm, there were
changes in the serum chemistries and a slight increase in the incidence of
parafollicular hyperplasia seen in the thyroids. Body weight gains were reduced
at 900 and 1800 ppm. The overall NOEL was 100 ppm.
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11.TOXICOLOGICAL INFORMATION (Continued)
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CARCINOGENICITY : Imidacloprid was investigated for carcinogenicity in chronic
feeding studies using mice and rats at maximum levels of 2000 and 1800 ppm,
respectively. There was no evidence of a carcinogenic potential observed in
either species.
MUTAGENICITY : The imidacloprid mutagenicity studies, taken
collectively, demonstrate that the active ingredient is not genotoxic or
mutagenic.
DEVELOPMENTAL TOXICITY: In a developmental toxicity study using rats,
imidacloprid was administered by oral gavage during gestation at doses of 10, 30
or 100 mg/kg. At the maternally toxic dose of 100 mg/kg, skeletal examinations
of the fetuses revealed a slight increase in the incidence of wavy ribs. The
NOELs for maternal and developmental toxicity were 10 and 30 mg/kg,
respectively. Teratogenic effects were not observed at any of the doses
tested. Rabbits were administered imidacloprid during gestation at oral doses of
8, 24 or 72 mg/kg. At the maternally toxic dose of 72 mg/kg, reduced body
weights and delayed skeletal ossification were observed in the fetuses. The
NOELs for maternal and developmental toxicity were 8 and 24 mg/kg,
respectively. Teratogenic effects were not observed at any of the doses
tested.
REPRODUCTION : In a reproduction study, imidacloprid was administered to rats for
2 generations at dietary concentrations of 100, 250 or 700 ppm. Offspring at
700 ppm, exhibited reduced mean body weights and body weights gains. No other
reproductive effects were observed. The maternal and reproductive NOELs were
100 and 250 ppm, respectively.
NEUROTOXICITY : In an acute neurotoxicity screening study using rats,
imidacloprid was administered as a single oral dose at levels of 42, 151, or
307 mg/kg. Clinical observations and neurotoxicity evaluations were performed
over a period of 15 days followed by a neurohistopathological examination.
Deaths attributed to imidacloprid were observed at the high dose within a day of
treatment. The NOEL for motor and locomotor activity was 42 mg/kg for males.
Females at the low dose exhibited minimal decrease in activity in the figure-
eight maze. In a subsequent study, the NOEL for motor and locomotor activity
in females was 20 mg/kg. All clinical signs and neurobehavioral effects were
ascribed to acute cholinergic toxicity, with complete recovery at sub-lethal
doses within 7 days following treatment. The NOEL for neurotoxicity was 307
mg/kg based on the absence of treatment-related microscopic lesions in
skeletal muscle or neural tissue. In a 13 week neurotoxicity screening study,
imidacloprid was administered to rats at dietary concentrations of 140, 963 or
3027 ppm. At the mid- and high-dose, effects observed included reductions in
body weight and feed consumption, and clinical chemistry findings.
Neurobehavioral changes were observed only in males at the high dose. There
were no correlative micropathologic findings in muscle or neural tissues in any
animals at any treatment level. The NOEL for neurotoxicity was 3027 ppm. The
overall NOEL was 140 ppm.
12. ECOLOGICAL INFORMATION:
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This product is toxic to aquatic invertebrates. Bayer will provide a summary of
specific ecological effects data upon written request. As with any pesticide,
this product should be used according to label directions and should be kept
out of streams, lakes and other aquatic habitats of concern.
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13. DISPOSAL CONSIDERATIONS
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WASTE DISPOSAL METHOD: Follow container label instructions for disposal of
wastes generated during use in compliance with the product label. In other
situations, bury in an EPA-approved landfill or burn in an incinerator
approved for pesticide destruction. Do not reuse container.
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14. TRANSPORTATION INFORMATION:
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TECHNICAL SHIPPING NAME ........ : Imidacloprid
FREIGHT CLASS PACKAGE .......... : Insecticides, NOI-NMFC 102120
PRODUCT LABEL ................... : Not Noted
DOT (DOMESTIC SURFACE)
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HAZARD CLASS OR DIVISION : Non-Regulated
IMO / IMDG CODE (OCEAN)
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HAZARD CLASS DIVISION NUMBER...: Non-Regulated
ICAO / IATA (AIR)
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HAZARD CLASS DIVISION NUMBER...: Non-Regulated
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15. REGULATORY INFORMATION:
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OSHA STATUS .................. : This product is hazardous under the criteria of
the Federal OSHA Hazard Communication Standard 29
CFR 1910.1200.
TSCA STATUS ................... : This product is exempt from TSCA Regulation under
FIFRA Section 3 (2) (B) (ii) when used as a
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15.REGULATORY INFORMATION (Continued)
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pesticide.
CERCLA REPORTABLE QUANTITY..:
No components listed
SARA TITLE III:
SECTION 302 EXTREMELY
HAZARDOUS SUBSTANCES..:
None
SECTION 311/312
HAZARD CATEGORIES .... :
Immediate Health Hazard
SECTION 313
TOXIC CHEMICALS ............ : None
RCRA STATUS ................ :
If discarded in its purchased form, this product
would not be a hazardous waste either by listing
or by characteristic. However, under RCRA, it is
the responsibility of the product user to
determine at the time of disposal, whether a
material containing the product or derived from
the product should be classified as a hazardous
waste. (40 CFR 261.20-24)
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16. OTHER INFORMATION:
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NFPA 704M RATINGS: Health Flammability Reactivity Other
1 1 1
0=Insignificant 1=Slight 2=Moderate 3=High 4=Extreme
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This information is furnished without warranty, expressed or implied, except
that it is accurate to the best knowledge of Control Solutions, Inc. The data
on this sheet relates only to the specific material designated herein. Control
Solutions, Inc. assumes no legal responsibility for use or reliance upon these
data.
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