2,4-TOLUENE DIISOCYANATE 0339
March 1995
4-Methyl-meta-phenylene diisocyanate
CAS No: 584-84-9
2,4-Diisocyanatotoluene
RTECS No: CZ6300000
2,4-Diisocyanato-1-methylbenzene
UN No: 2078
C9H6N2O2 / CH3C6H3(NCO)2
EC No: 615-006-00-4
Molecular mass: 174.2
TYPES OF
ACUTE HAZARDS/SYMPTOMS PREVENTION FIRST AID/FIRE FIGHTING
HAZARD/
EXPOSURE
Combustible. Gives off irritating or NO open flames. NO contact with Powder, carbon dioxide. Use water
FIRE
toxic fumes (or gases) in a fire. water and active chemicals. ONLY in flooding amounts.
Closed containers may develop In case of fire: cool drums, etc., by
EXPLOSION
pressure and explode on exposure spraying with water but avoid
to heat or if contaminated with contact of the substance with water.
water or reactive chemicals. Combat fire from a sheltered
position.
EXPOSURE AVOID ALL CONTACT! IN ALL CASES CONSULT A
DOCTOR!
Abdominal pain. Cough. Nausea. Local exhaust. Breathing protection. Fresh air, rest. Half-upright position.
Inhalation
Shortness of breath. Sore throat. Artificial respiration may be needed.
Vomiting. Symptoms may be Refer for medical attention.
delayed (see Notes).
Redness. Burning sensation. Pain. Protective gloves. Protective Rinse and then wash skin with water
Skin
clothing. and soap. Refer for medical
attention.
Redness. Pain. Blurred vision. Face shield or eye protection in First rinse with plenty of water for
Eyes
combination with breathing several minutes (remove contact
protection. lenses if easily possible), then take
to a doctor.
(Further see Inhalation). Do not eat, drink, or smoke during Rinse mouth. Give a slurry of
Ingestion
work. activated charcoal in water to drink.
Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Evacuate danger area! Consult an expert in case of T+ Symbol Do not transport with food and
a large spillage! Collect leaking liquid in covered R: 26-36/37/38-40-42/43-52/53 feedstuffs.
containers. Treat remaining liquid with a mixture of S: (1/2-)23-36/37-45-61
ammonia (4-8%), detergent (2%), and water. Absorb Note: C
remaining liquid in sand or inert absorbent and UN Hazard Class: 6.1
remove to safe place. If solid collect the substance UN Pack Group: II
into containers. Personal protection: complete
protective clothing including self-contained breathing
apparatus.
EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61S2078 or Recommended storage temperature 20-25/C. Separated from food and
61GT1-II feedstuffs. See Chemical Dangers. Dry. Keep in a well-ventilated room.
NFPA Code: H3; F1; R1
IPCS Prepared in the context of cooperation between the International
Programme on Chemical Safety and the European Commission 漏
International IPCS 2005
Programme on
Chemical Safety SEE IMPORTANT INFORMATION ON THE BACK.
0339 2,4-TOLUENE DIISOCYANATE
IMPORTANT DATA
Physical State; Appearance Routes of exposure
COLOURLESS TO PALE YELLOW LIQUID OR CRYSTALS, The substance can be absorbed into the body by inhalation of
WITH PUNGENT ODOUR. TURNS PALE YELLOW ON its vapour and by inhalation of its aerosol and by ingestion.
EXPOSURE TO AIR.
Inhalation risk
Chemical dangers A harmful contamination of the air can be reached rather quickly
The substance may polymerize under the influence of bases, on evaporation of this substance at 20/C.
tertiary amines and acyl chlorides with fire or explosion hazard.
On combustion, forms toxic vapours and gases including Effects of short-term exposure
nitrogen oxides and isocyanates. Reacts readily with water, The substance, the vapour of this substance and the aerosol is
acids and alcohols causing pressure rise explosion hazard. irritating to the eyes, the skin and the respiratory tract. Inhalation
of the vapour may cause asthma-like reactions. Inhalation of the
Occupational exposure limits vapour may cause chemical bronchitis, pneumonitis and lung
TLV: 0.005 ppm as TWA; 0.02 ppm as STEL; A4 (not oedema. Exposure far above the OEL may result in death. The
classifiable as a human carcinogen); SEN (ACGIH 2004). effects may be delayed. Medical observation is indicated.
MAK: sensitization of respiratory tract (Sa); Carcinogen
category: 3A; (DFG 2004). Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization.
Repeated or prolonged inhalation exposure may cause asthma.
This substance is possibly carcinogenic to humans.
PHYSICAL PROPERTIES
Boiling point: 251/C Relative density of the vapour/air-mixture at 20/C (air = 1): 1.00
Melting point: 22/C Flash point: 127/C c.c.
Relative density (water = 1): 1.2 Auto-ignition temperature: 620/C
Solubility in water: reaction Explosive limits, vol% in air: 0.9-9.5
Vapour pressure, Pa at 20/C: 1.3 Octanol/water partition coefficient as log Pow: 0.21
Relative vapour density (air = 1): 6.0
ENVIRONMENTAL DATA
NOTES
Technical toluene diisocyanate is a mixture of 2,4- and 2,6-isomers (80:20), TDI is a common name.
Depending on the degree of exposure, periodic medical examination is suggested.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Anyone who has shown symptoms of asthma due to this substance should avoid all further contact with this substance.
The odour warning when the exposure limit value is exceeded is insufficient.
Card has been partly updated in April 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.
ADDITIONAL INFORMATION
Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible
LEGAL NOTICE
漏IPCS 2005
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