para-TOLUIDINE 0343
March 1995
CAS No: 106-49-0 4-Amino-1-methylbenzene
RTECS No: XU3150000 4-Aminotoluene
UN No: 3451 p-Methylaniline
EC No: 612-160-00-4 C7H9N / C6H4CH3NH2
Molecular mass: 107.2
TYPES OF
ACUTE HAZARDS/SYMPTOMS PREVENTION FIRST AID/FIRE FIGHTING
HAZARD/
EXPOSURE
FIRE Combustible. Gives off irritating or toxic NO open flames. NO contact with nitric Powder. Foam. Carbon dioxide.
fumes (or gases) in a fire. acid.
EXPLOSION Above 86/C explosive vapour/air Above 86/C use a closed system, In case of fire: keep drums, etc., cool by
mixtures may be formed. ventilation. spraying with water.
EXPOSURE PREVENT DISPERSION OF DUST! IN ALL CASES CONSULT A DOCTOR!
STRICT HYGIENE!
Inhalation Blue lips or finger nails. Blue skin. Local exhaust or breathing protection. Fresh air, rest. Artificial respiration may
Confusion. Dizziness. Headache. be needed. Refer for medical attention.
Laboured breathing. Nausea. Shortness
of breath. Unconsciousness. Weakness.
Skin MAY BE ABSORBED! Redness. Blue Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and
lips or fingernails. Blue skin. (Further then wash skin with water and soap.
see Inhalation). Refer for medical attention.
Eyes Redness. Pain. Severe deep burns. Safety goggles. First rinse with plenty of water for several
minutes (remove contact lenses if easily
possible), then take to a doctor.
Ingestion Blue lips or fingernails. Blue skin. Do not eat, drink, or smoke during work. Rinse mouth. Induce vomiting (ONLY IN
Dizziness. Headache. Laboured CONSCIOUS PERSONS!). Refer for
breathing. (Further see Inhalation). medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Sweep spilled substance into sealable containers. Carefully EU classification Do not transport with food and feedstuffs.
collect remainder, then remove to safe place. Personal T Symbol
protection: complete protective clothing including N Symbol
self-contained breathing apparatus. R: 23/24/25-36-40-43-50
S: (1/2-)28-36/37-45-61
UN classification
UN Hazard Class: 6.1
UN Pack Group: II
EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT2-II Separated from strong oxidants, strong acids, food and feedstuffs. Cool. Dry. Well
NFPA Code: H3; F2; R0 closed. Ventilation along the floor.
Prepared in the context of cooperation between the International
IPCS Programme on Chemical Safety and the European Commission 漏
IPCS 2006
International
Programme on
SEE IMPORTANT INFORMATION ON THE BACK.
Chemical Safety
0343 para-TOLUIDINE
IMPORTANT DATA
Physical State; Appearance Routes of exposure
COLOURLESS FLAKES TURNS DARK ON EXPOSURE TO AIR AND The substance can be absorbed into the body by inhalation and through
LIGHT. the skin and by ingestion.
Chemical dangers Inhalation risk
The substance decomposes on heating or on burning producing toxic Evaporation at 20/C is negligible; a harmful concentration of airborne
fumes including nitrogen oxides. Reacts violently with oxidants, especially particles can, however, be reached quickly on spraying or when
nitric acid. dispersed, especially if powdered.
Occupational exposure limits Effects of short-term exposure
TLV: 2 ppm as TWA; (skin); A3 (confirmed animal carcinogen with The substance irritates the eyes and the skin. The substance may cause
unknown relevance to humans); BEI issued; (ACGIH 2004). effects on the blood, bladder and kidneys, resulting in tissue lesions and
MAK: skin absorption (H); sensitization of skin (Sh); Carcinogen category: formation of methaemoglobin. Exposure to high concentrations may result
3B; (DFG 2007). in damage to kidneys and bladder. The effects may be delayed. Medical
observation is indicated. See Notes.
Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. The
substance may have effects on the blood, resulting in formation of
methaemoglobin (see Notes).
PHYSICAL PROPERTIES
Boiling point: 200/C Relative vapour density (air = 1): 3.9
Melting point: 44-45/C Flash point: 86-87/C c.c.
Relative density (water = 1): 1.05 Auto-ignition temperature: 482/C
Solubility in water: poor Explosive limits, vol% in air: 1.1-6.6
Vapour pressure, kPa at 42/C: 0.13 Octanol/water partition coefficient as log Pow: 1.39
ENVIRONMENTAL DATA
NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
The odour warning when the exposure limit value is exceeded is insufficient.
Do NOT take working clothes home.
Also consult ICSC # 0341 ortho-Toluidine and 0342 meta-Toluidine.
Card has been partly updated in October 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.
Card has been partially updated in January 2008: see Fire fighting.
ADDITIONAL INFORMATION
Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible
LEGAL NOTICE for the use which might be made of this information
漏IPCS 2006
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