ARSENIC PENTOXIDE 0377
March 1998
CAS No: 1303-28-2 Arsenic (V) oxide
Arsenic acid anhydride
RTECS No: CG2275000
Arsenic anhydride
UN No: 1559
As 2O5
EC No: 033-004-00-6
Molecular mass: 229.8
TYPES OF
ACUTE HAZARDS/SYMPTOMS PREVENTION FIRST AID/FIRE FIGHTING
HAZARD/
EXPOSURE
FIRE Not combustible. Gives off irritating In case of fire in the surroundings:
or toxic fumes (or gases) in a fire. use appropriate extinguishing media.
EXPLOSION
EXPOSURE PREVENT DISPERSION OF DUST! IN ALL CASES CONSULT A
AVOID ALL CONTACT! DOCTOR!
Inhalation Cough. Sore throat. Headache. Local exhaust or breathing protection. Fresh air, rest. Half-upright position.
Dizziness. Weakness. Shortness of Artificial respiration if indicated. Refer
breath. Pain in chest. Symptoms for medical attention.
may be delayed (see Notes), (see
Ingestion).
Skin Redness. Burning sensation. Pain. Protective gloves. Protective clothing. Remove contaminated clothes.
Rinse and then wash skin with water
and soap. Refer for medical
attention.
Eyes Redness. Pain. Safety goggles or eye protection in First rinse with plenty of water for
combination with breathing protection several minutes (remove contact
if powder. lenses if easily possible), then take to
a doctor.
Ingestion Vomiting. Abdominal pain. Do not eat, drink, or smoke during Rinse mouth. Induce vomiting (ONLY
Diarrhoea. Severe thirst, muscular work. Wash hands before eating. IN CONSCIOUS PERSONS!). Rest.
cramps, shock. (See Inhalation). Refer for medical attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Do NOT wash away into sewer. Sweep spilled T Symbol Unbreakable packaging; put
substance into containers; if appropriate, moisten first N Symbol breakable packaging into closed
to prevent dusting. Carefully collect remainder, then R: 45-23/25-50/53 unbreakable container. Do not
remove to safe place. Remove airborne particles with S: 53-45-60-61 transport with food and feedstuffs.
fine water spray. Do NOT let this chemical enter the Note: E Marine pollutant.
environment. Personal protection: chemical protection UN Hazard Class: 6.1
suit including self-contained breathing apparatus. UN Pack Group: II
EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT5-II Separated from strong bases, reducing substances, food and feedstuffs. Dry.
NFPA Code: H2; F0; R0 Well closed.
Prepared in the context of cooperation between the International
IPCS Programme on Chemical Safety and the European Commission 漏
IPCS 2005
International
Programme on
SEE IMPORTANT INFORMATION ON THE BACK.
Chemical Safety
0377 ARSENIC PENTOXIDE
IMPORTANT DATA
Physical State; Appearance Routes of exposure
WHITE HYGROSCOPIC POWDER. The substance can be absorbed into the body by inhalation of its
aerosol and by ingestion.
Chemical dangers
Inhalation risk
The substance decomposes on heating above 300/C producing
toxic fumes (arsenic trioxide - see ICSC 0378) and oxygen. The Evaporation at 20/C is negligible; a harmful concentration of
solution in water is a weak acid. Reacts violently with bromine airborne particles can, however, be reached quickly.
pentafluoride causing fire and explosion hazard. Reacts with
reducing agents, producing very toxic gas (arsine - ICSC 0222). Effects of short-term exposure
Attacks many metals in presence of water or moisture. The substance is irritating to the eyes, the skin and the respiratory
tract. The substance may cause effects on the blood,
Occupational exposure limits cardiovascular system, peripheral nervous system and liver.
TLV: (as As) 0.01 mg/m 3 as TWA; A1 (confirmed human Exposure far above the OEL may result in death. The effects may
carcinogen); BEI issued; (ACGIH 2004). be delayed (see Notes). Medical observation is indicated.
MAK: Carcinogen category: 1; Germ cell mutagen group: 3A;
(DFG 2004). Effects of long-term or repeated exposure
The substance may have effects on the skin (hyperkeratosis),
cardiovascular system, peripheral nervous system, bone marrow
(hematopoietic changes), liver, and lungs. This substance is
carcinogenic to humans.
PHYSICAL PROPERTIES
Melting point (decomposes): 315/C Solubility in water, g/100 ml at 20/C: 65.8
Density: 4.3 g/cm3
ENVIRONMENTAL DATA
This substance may be hazardous to the environment; special attention should be given to fauna and water organisms.
NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
The symptoms of acute poisoning do not become manifest until some hours.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
No odour warning if toxic concentrations are present.
Do NOT take working clothes home.
The recommendations on this Card also apply to inorganic pentavalent arsenic compounds (arsenates).
Card has been partly updated in October 2005. See sections Occupational Exposure Limits, EU classification, Emergency Response.
ADDITIONAL INFORMATION
Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible
LEGAL NOTICE for the use which might be made of this information
漏IPCS 2005
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