MATERIAL SAFETY DATA SHEET
1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
Product: BAN Phase Separation Reagent
Cat. No: BN 191
Molecular Research Center, Inc.
5645 Montgomery Rd.
Cincinnati, Ohio 45212
USA 1-888-841-0090
Product Name: BAN Phase Separation Reagent
Chemical Formula: BrC6H4OCH3
Molecular Weight: 187.03
Synonyms: 1-Bromo-4-methoxybenzene; p-Bromanisole; p-Anisyl bromide.
NFPA RATINGS: (estimated) Health=1 Fire=1 Reactivity=0
HMIS RATINGS: estimated (scale 0-4) Health=1 Fire=1 Reactivity=0 PPE=H
CHEMTREC EMERGENCY NUMBER 800-424-9300
2. COMPOSITION / INFORMATION ON INGREDIENTS
Component CAS No Percent
4-Bromoanisole 104-92-7 > 98 %
EINECS No.
203-252-1
3. HAZARD IDENTIFICATION
EMERGENCY OVERVIEW: A clear to colorless to pale yellow liquid. Caution! May cause eye, skin or respiratory
tract irritation. May be harmful if absorbed through skin, if swallowed or inhaled. No information is currently listed
regarding target organs, hazard symbols or risk phrases.
4. FIRST AID
EYE CONTACT: Check for and remove any contact lenses. Flush eyes with water for 15 min., holding eyelids open.
Obtain medical attention.
SKIN CONTACT: Flush skin with soap and water for 15 min. Remove contaminated clothing and thoroughly wash
before reuse.
INHALATION: Remove from exposure to fresh air. If not breathing, give artificial respiration. Obtain medical
attention. Treat symptomatically and supportively.
INGESTION: If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Do not induce vomiting unless
directed so by medical personnel. Obtain medical attention. Loosen tight clothing such as a collar, tie, belt or waistband.
5. FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA: May be combustible at high temperatures. Extinguishing media appropriate to
surrounding fire conditions. Small Fire: Use dry chemical powder. Large Fire: Use water spray, fog or foam. Do not
use water jet. May emit toxic fumes under fire conditions (bromide). Vapors may be heavier than air and they can
spread along the floor and collect in low or confined areas.
SPECIAL FIRE FIGHTING PROCEDURES: Wear self-contained breathing apparatus and protective clothing to
prevent contact with skin and eyes. In a fire, protective gear and a self-contained breathing apparatus in pressure-
demand, MSHA/NIOSH (approved or equivalent) is recommended.
6. ACCIDENTAL RELEASE MEASURES
PERSONAL PROTECTIVE EQUIPMENT FOR SPILL CONDITIONS: Note that accidental releases may be
subject to special state or local reporting requirements and other regulatory mandates. Check and comply with local laws
and regulations. Use gloves and other appropriate protective covering to avoid skin contact. Ensure adequate ventilation.
Use goggles, face shield or other eye protection. Contain spill with an inert adsorbent such as vermiculite, sand or earth.
Place spill material in a suitable container and hold for disposal. Avoid breathing vapor, mist or gas.
7. HANDLING AND STORAGE
Store in a cool, dry place in sealed containers. Practice good laboratory techniques when handling this substance. After
using the chemical, wash hands thoroughly. Use adequate ventilation and avoid breathing vapor, mist or gas. Empty
containers pose a fire risk and any residue should be evaporated under a fume hood. Keep away from incompatibles such
as oxidizing agents, metals and alkali.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
For routine operations wear safety glasses, latex gloves and a lab coat to avoid contact with eyes, skin and clothing.
Facilities utilizing this chemical should be equipped with an eyewash station and safety shower. Use adequate ventilation
to keep airborne concentrations below the permissible exposure limits. (No PELS are listed for this chemical). Personal
Protective Equipment: Chemical splash goggles, protective gloves and clothing to prevent eye and skin exposure.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance: Clear, colorless to pale yellow liquid
Odor: none reported
Vapor Pressure: not reported
1.4940 g/cm3
Density:
Boiling point: 223 C @760 mm Hg (433.4 F)
Melting point: 9-10 C
Flash point: 94 C (201.20 F)
Solubility in water: Immiscible
10. STABILITY AND REACTIVITY
Stable under normal temperatures and pressures.
INCOMPATIBILITIES: Heat, ignition sources, strong acids, strong oxidizing agents.
DECOMBUSTION PRODUCTS: Carbon monoxide, carbon dioxide, and hydrogen bromide gas. Hazardous
polymerization reactions have not been reported.
11. TOXICOLOGICAL INFORMATION
RTECS# BZ8501000 CAS# 104-92-7
Rat: Inhalation: oral LD50=3800 mg/kg; LD50 (skin) 3200 mg/kg. Mouse: oral LD50=2200 mg/kg. Inhalation LC50=
20 mg/m3.
CARCINOGENICITY: Not listed by ACGIH, IARC, NTP or CA Prop 65.
To the best of our knowledge the acute and chronic toxicity of this substance is not fully known.
12. ECOLOGICAL INFORMATION
ECOTOXICITY: Bacteria: Phytobacterium phosphoreum, EC50=2.25-2.58 mg/L; 5, 15 and 30 minutes. Microtox test,
15 C.
13. DISPOSAL CONSIDERATIONS
Keep in sealed containers until final disposal. Dispose of in a manner consistent with federal, state and local regulations.
Not listed as banned from land disposal according to RCRA.
14. TRANSPORT INFORMATION
Not regulated for domestic US DOT transport or Canada TDG.
15. REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/ Protection) CAS # 1104-92-7 Not available
United Kingdom Occupational Exposure Limits
Canada: CAS# 104-92-7 is listed in Canada鈥檚 DSL List. WHMIS classification D2L.
US Federal:
TSCA: CAS # 104-92-7 is listed on the TSCA inventory.
Health and Safety Reporting: The chemical is not on the health & safety reporting list.
Chemical Test Rules: This chemical is not under a chemical test rule.
Section 12b: This chemical is not listed under TSCA Section 12b.
TSCA Significant New Use Rule: This chemical is not listed under SNUR.
CERCLA Hazardous Substances and corresponding RQ鈥檚: This chemical does not have an RQ
SARA Section 302 Extremely Hazardous Substances: no listed TPQ.
SARA Codes: CAS# 104-92-7: immediate, reactive.
Section 313: Not reported under section 313.
Clean Air Act: The chemical is not classified as a hazardous air pollutant or a Class 1or 2 ozone depletory.
Clean Water Act: This chemical is not listed as a hazardous substance, priority pollutant or a toxic pollutant
under the CWA.
State: CAS # 104-92-7 is not listed or present on CA, PA, MN, MA, FL or NJ state lists.
16. OTHER INFORMATION
Reviewed by BW, MJ
Revision date 1/02/08
This information is believed to be accurate and represents the information currently available to us. However, we make
no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we
assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
information for their particular purposes.
Abbreviations:
N/A Not Applicable
N.D.A. No data available
TLV-STEL Threshold Limit Values (Short-Term Exposure Limit)
TLV-TWA Threshold Limit Values (Time-Weighted Average)
OSHA PEL-TWA OSHA Permissible Exposure Level
|