MATERIAL SAFETY DATA SHEET





1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION



Product:          High Efficiency Hybridization System (with or without formamide).

Cat. No:          HS 114, HS 114F



Molecular Research Center, Inc.

5645 Montgomery Rd.

Cincinnati, Ohio 45212

USA 1-888-841-0900



Product Name: High Efficiency Hybridization System

Chemical Formula: A formulation.

Molecular Weight: N/A

HMIS Rating (scale 0-4) Health=2 Fire=1 Reactivity= 0            PPE=C



CHEMTREC EMERGENCY NUMBER: 1-703-527-3887





2. COMPOSITION / INFORMATION ON INGREDIENTS



Component        CAS No.            Percent

High Efficiency Hyb Solution        N/A                Proprietary Information

Formamide                           75-12-7            < 50 % (Note: Ingredient of HS-114F only)





3. HAZARD IDENTIFICATION



ROUTES OF EXPOSURE:                 Skin               Yes

                                    Ingestion          Yes

                                    Inhalation         Yes



ACUTE EFFECTS: Causes eye and skin irritation. Exposure may cause irritation to mucous membranes and upper

respiratory tract. Harmful if swallowed.



CHRONIC EFFECTS: Prolonged or repeated exposure to reagents containing formamide may cause adverse reproductive

effects. May cause fetal effects. See FORMAzol MSDS for more detailed information relating to formamide.





4. FIRST AID



In case of contact, immediately flush eyes or skin with water for at least 15 min while removing contaminated clothing and

shoes. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If

swallowed, wash out mouth with water provided person is conscious. If victim is conscious and alert, give 2-4 cupfuls of

milk or water. Seek medical attention. Wash contaminated clothing before reuse.





5. FIRE FIGHTING MEASURES



Negligible fire hazard when exposed to heat or flame. Extinguishing media: water spray, carbon dioxide, dry chemical

powder or appropriate foam. Special fire fighting procedures: may emit toxic fumes under fire conditions. Wear self-

contained breathing apparatus and protective clothing to prevent contact with skin and eyes.





6. ACCIDENTAL RELEASE MEASURES

Evacuate unnecessary personnel from area. Provide adequate general or local exhaust ventilation. If adequate

ventilation is unavailable, wear self-contained breathing apparatus. Wear appropriate protective eyeglasses or

chemical safety goggles. Wear appropriate protective gloves and protective clothing to prevent skin exposure.

Absorb on sand or vermiculite and place in containers for disposal. Ventilate area and wash spill site after material

pickup is complete.





7. HANDLING AND STORAGE



Irritant. Keep container closed. Store in a cool dry place. Wear lab coat, gloves and eye protection and provide adequate

ventilation. Avoid contact with skin, eyes and clothing. Wash hands thoroughly after handling.





8. EXPOSURE CONTROLS/ PERSONAL PROTECTION



For routine operations wear lab coat, gloves and safety glasses to avoid contact with eyes, skin and clothing. Ensure

availability of eyewash and safety shower. Avoid prolonged or repeated inhalation and skin exposure.





9. PHYSICAL AND CHEMICAL PROPERTIES



Appearance:      Clear, light orange liquid

Assay:           >99 %

Solubility:      Water, ethanol





10. STABILITY AND REACTIVITY



STABILITY: Stable under normal temperatures and pressures.



INCOMPATIBILITIES: Strong oxidizing agents, bromine trifluoride, iodine heptafluoride and potassium chlorate. In

addition, HS-114F (with formamide) is incompatible with aluminum, acids, bases, calcium nitrate, pyridine, iodine and

sulfur trioxide.



HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS: Toxic fumes of carbon monoxide, carbon

dioxide, nitrogen oxides, ammonia and chlorine.





11. TOXICOLOGICAL INFORMATION



May be harmful by inhalation, ingestion, or skin absorption. Causes eye and skin irritation. Material is irritating to mucous

membranes and upper respiratory tract. To the best of our knowledge, the chemical, physical, and toxicological properties of

this formulation have not been thoroughly investigated. HS-114F containing formamide may pose a potential birth defect

hazard.





12. ECOLOGICAL INFORMATION                    No data available.





13. DISPOSAL INFORMATION



Dissolve or mix with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.

Observe all federal, state and local environmental regulations.





14. TRANSPORT INFORMATION                     No data available.





15. REGULATORY INFORMATION                    No data available.

16. OTHER INFORMATION               Reviewed by       BW, MJ

                                    Revision date     5/01/07



This information is believed to be accurate and represents the information currently available to us. However, we make no

warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no

liability resulting from its use. Users should make their own investigations to determine the suitability of the information for

their particular purposes.



Abbreviations:

        N/A                         Not Applicable