MATERIAL SAFETY DATA SHEET



1. CHEMICAL PRODUCT AND COMPANY INDENTIFICATION



Product:          FORMAzol

Cat. No:          FO 121



Molecular Research Center

5645 Montgomery Rd.

Cincinnati, Ohio 45212

USA 1-888-841-0900



Product Name: FORMAzol

Chemical Name: A formulation

Molecular Weight: 45.04

Synonyms: Carbamaldehyde, Methanamide



NFPA RATINGS: (Scale 0-4)         Health=2                     Fire=1 Reactivity=0        PPE=D*

HMIS RATINGS: (Scale 0-4)         Health=2                     Fire=1 Reactivity=0

Use chemical fume hood for adequate ventilation.



CHEMTREC EMERGENCY NUMBER 1-703-527-3887





2. COMPOSITION AND INFORMATION ON INGREDIENTS



Component                  CAS No.           EINECS/ELINCS              Percent

Formamide                  75-12-7             200-842-0                Proprietary Information





3. HEALTH HAZARD INFORMATION



EFFECTS OF OVEREXPOSURE: May cause respiratory and digestive tract irritation. May cause eye and skin irritation.

May cause reproductive and fetal effects. Target organs: Central nervous system, liver, eyes, reproductive system, skin, mucous

membranes.



ROUTES OF ENTRY:           Inhalation        Yes

                           Skin              Yes

                           Ingestion         Yes

ACUTE EFFECTS



EYE EXPOSURE: May cause eye irritation.



SKIN EXPOSURE: May cause skin irritation and mucus membrane irritation. Symptoms include redness, itching and pain.

Harmful if exposed through skin. Not expected to cause an allergic reaction.



INGESTION: May cause irritation of the digestive tract. Affects the central nervous system. May cause headache, dizziness,

nausea, vomiting, abdominal pain, and unconsciousness. May affect reproductive system.



INHALATION: May cause respiratory tract irritation. Inhalation of high concentrations may cause central nervous system

effects including headache, dizziness, unconsciousness and coma.

CHRONIC EFFECTS



Prolonged and repeated exposure may cause birth defects including congenital malformation in the fetus. Chronic exposure may

cause liver damage. There is a danger of cumulative effects.





4. FIRST AID



EYE CONTACT: Immediately flush eyes with copious amounts of water for 15 minutes while lifting upper and lower lids. Get

medical attention.



SKIN CONTACT: Remove contaminated clothing. Flush skin with soap and water for 15 minutes. Get medical treatment if

irritation develops and persists.



INHALATION: Remove to fresh air. Get medical aid immediately. If not breathing, give artificial respiration. If breathing is

difficult, give oxygen.



INGESTION: If victim is conscious, wash mouth out with water. If swallowed, do not induce vomiting unless directed to do so

by medical personnel. Get medical attention immediately.





5. FIRE AND EXPLOSION HAZARD DATA



Emits toxic fumes under fire conditions such as carbon monoxide, and ammonia. Wear self-contained breathing apparatus and

MSHA/NIOSH approved protective gear.



Flash point:              309 F, 154 C Moderate fie hazard when heated.

Explosion limits:         lower 2.70 (% by volume)

                          upper 19.00

Autoignition temperature: 932 F



EXTINGUISHING MEDIA: Water spray, water foam, carbon dioxide, dry chemicals. Wear self-contained breathing apparatus

or approved respirator.





6. ACCIDENTAL RELEASE MEASURES



PERSONAL PROTECTIVE EQUIPMENT: Use gloves, boots, safety glasses, other impervious clothing to avoid skin

contact.



SPILLS OR LEAKS: Ventilate area of leak or spill. Wear self-contained breathing apparatus and MSHA/NIOSH approved

protective gear. Absorb spill with earth, sand, vermiculite or other non-combustible material and place in sealed containers. Do

not use combustible materials such as saw dust and do not flush into sewer.





7. HANDLING AND STORAGE



Use with adequate ventilation and wash hands thoroughly after handling. Store the reagent in a cool, dry and well-ventilated area.

 Refrigeration may be appropriate for long-term storage or sporadic use. Keep container tightly closed to avoid exposure. Do not

store in direct sunlight.





8. EXPOSURE CONTROLS, PERSONAL PROTECTION

PERSONAL PROTECTIVE EQUIPMENT: Wear appropriate eye protection, gloves and lab coat for routine operations. Do

not eat or drink in area where reagent is used. Avoid contact with skin and eyes. Do not breathe vapor. Laboratory should be

equipped with an eye wash station





9. PHYSICAL AND CHEMICAL PROPERTIES



Description:               Clear, colorless liquid with weak ammonia-like odor

Chemical formula:          CH3NO

Molecular weight:          45.04

Melting point:             2-4 C

Boiling point:             210 C

                           Density 1.132 g/cm3

Vapor pressure:            .06 mm Hg @ 25 C

Solubility:                misc. with water

                           Sol. in ethanol, acetone

pH value:                  4-5 (20% in water, 20 C)





10. STABILITY AND REACTIVITY



STABILITY: Stable at room temperature and pressure. Avoid ignition sources, excess heat. Avoid light, moisture and

temperatures above 180 C.



INCOMPATIBILITIES: Aluminum, acids, bases, strong oxidizing agents, calcium nitrate, iodine, pyridine and sulfur trioxide.

Copper, brass, lead and rubber are attacked by formamide.



HAZARDOUS DECOMPOSITION PRODUCTS: Nitrogen oxides, carbon monoxide and carbon dioxide. At the boiling

point, ammonia, carbon dioxide and hydrogen cyanide are liberated.





11. TOXICOLOGICAL INFORMATION



TOXICITY DATA: Rat: Oral acute LD50 = 5570mg/kg; Inhalation >3900 ppm / 6h. Mouse: Oral LD50 = 3150 mg/kg.

Draize test, rabbit, eye: 100 mg Severe. Skin rabbit: LD 50 =17 gm / kg. Investigated as a tumorigen, mutagen and reproductive

effector.



Carcinogenicity: Not listed by ACGIH, IARC, NIOSH, or OSHA.

Teratogenicity: Embyro or fetus: Death, skin-rat = 1200 mg / kg; stunted fetus growth. Oral-rat TDLO = 2 g / kg; Specific

Developmental Abnormalities: craniofacial and musculoskeletal, oral-rat TDLO = 7980 mg/kg.

Mutagenicity: RTECS # LQ0525000 for mutation data.





12. ECOLOGICAL INFORMATION



ECOTOXICITY: When released into the soil, formamide may be biodegradable but it is expected to leach into the ground

water. The chemical has an estimated bioconcentration factor (BCF) of less than 100. When released into the air, this material is

expected to readily degrade by reaction with photochemically produced hydroxyl radicals with a half-life of less than 1 day.

Minnow LC50 =500 mg / L / 48 h.





13. DISPOSAL CONSIDERATIONS

Observe all federal, state and local regulations. US EPA guidelines for the classification determination are listed in 40 CFR Parts

261.3.





14. TRANSPORT INFORMATION



US ODOT N/A

IMO Not regulated as hazardous material.

IATA Not regulated as hazardous material.

RID/ADR Not regulated as hazardous material.





15. REGULATORY INFORMATION



OSHA:                       Not considered highly hazardous

TSCA:                       CAS#75-12-7 IS TSCA LISTED

SARA CODES:                 CAS#75-12-7 ACUTE, CHRONIC

EINECS NO:                  200 842 0

RISK PHRASES:               36/37/38/47

SAFETY PHRASES:             23/26/36/53







16. OTHER INFORMATION                 Reviewed by        BW, MJ

                                      Revision date      5/01/07



This information is believed to be accurate and represents the information currently available to us. However, we make no

warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no

liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their

particular purposes.



Abbreviations:

N/A                         Not Applicable

N.D.A.                      No data available

TLV-STEL                    Threshold Limit Values (Short-Term Exposure Limit)

TLV-TWA                     Threshold Limit Values (Time-Weighted Average)

OSHA PEL-TWA                OSHA Permissible Exposure Level