MATERIAL SAFETY DATA SHEET Page: 1
O-1918
Cayman Chemical Company
Printed: 10/24/2005
1180 E. Ellsworth Rd.
Revision: 10/24/2005
Ann Arbor, MI 48108
Date Created: 10/24/2005
1. Product and Company Identification
Product Code: 10004914
Product Name: O-1918
Manufacturer Information
Company Name: Cayman Chemical Company
Emergency Contact: Cayman Chemical Company (800)364-9897
Information: Cayman Chemical Company (734)971-3335
Chemical Family: Agonists & Antgonists
Synonyms: 1,3-dimethoxy-5-methyl-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2 -cyclohexen-1-yl]-benzene
2. Composition/Information on Ingredients
Hazardous Components (Chemical Name) CAS # Percentage OSHA PEL ACGIH TWA Other Limits
1. O-1918 536697-79-7 1.0 % No data. No data. No data.
2. Methyl acetate 79-20-9 99.0 % 8H TWA:200 ppm 200 ppm No data.
(610 mg/m3)
Hazardous Components (Chemical Name) RTECS # OSHA STEL OSHA CEIL ACGIH STEL ACGIH CEIL
1. O-1918 NA No data. No data. No data. No data.
2. Methyl acetate AI9100000 No data. No data. 250 ppm No data.
3. Hazards Identification
Emergency Overview: No data available.
Route(s) of Entry: Inhalation? Yes Skin? Yes Eyes? Yes Ingestion? Yes Other: Injection
Potential Health Effects (Acute and Chronic): The hazards identified with this product are those associated with the solvent(s).
Material is irritating to the mucous membranes and upper respiratory tract.
May be harmful by inhalation, ingestion, or skin absorption.
May cause eye, skin, or respiratory system irritation.
Repeated exposure may cause skin dryness or cracking.
The toxicological properties of this compound have not been fully evaluated.
Vapors may cause drowsiness and dizziness.
LD 50/LC 50: Please refer to Section 11.
Signs and Symptoms Of Exposure: Methyl acetate is metabolized into formic acid. Humans and other primates metabolize formic
acid more slowly than do rodents. Formic acid can build up in the body producing toxic effects
possibly leading to death; therefore data from studies in rodents may have limited relevance for
human risk assessment.
4. First Aid Measures
Emergency and First Aid Procedures: If inhaled remove to fresh air. If not breathing, give artificial respiration or give oxygen by trained
personnel. Get immediate medical attention.
If swallowed, wash out mouth with water provided person is conscious. Never give anything by
mouth to an unconscious person. Get medical attention. Do NOT induce vomiting unless directed
to do so by medical personnel.
In case of contact with eyes, hold eyelids apart and flush eyes with plenty of water. After initial
flushings, remove any contact lenses and continue flushing for at least 20 minutes. Have eyes
examined and tested by medical personnel.
In case of skin contact, immediately wash skin with soap and plenty of water. Remove
contaminated clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
ANSI Z400.1 Format
MATERIAL SAFETY DATA SHEET Page: 2
Printed: 10/24/2005
O-1918 Revision: 10/24/2005
5. Fire Fighting Measures
Flash Pt: -10.00 C
Explosive Limits: LEL: 3.1% at 25.0 C UEL: 16% at 25.0 C
Autoignition Pt: 502.00 C
Fire Fighting Instructions: As in any fire, wear self-contained breathing apparatus pressure-demand (MSHA/NIOSH
approved or equivalent), and full protective gear to prevent contact with skin and eyes.
Note: Flammable as diluted in methyl acetate
Flammable Properties and Hazards: Can release vapors that form explosive mixtures at temperatures at or above the flash point.
Container explosion may occur under fire conditions.
Emits toxic fumes under fire conditions.
Flammable liquid.
Vapors can travel to a source of ignition and flash back.
Extinguishing Media: Use alcohol-resistant foam, carbon dioxide, water, or dry chemical spray when fighting fires
involving this material.
Use of water spray when fire fighting may be inefficient.
Use water spray to cool fire-exposed containers.
Unsuitable Extinguishing Media: No data available.
6. Accidental Release Measures
Steps To Be Taken In Case Material Is Wear a government approved respirator and appropriate personal protection (rubber boots, safety
Released Or Spilled: goggles, and heavy rubber gloves).
Absorb spill with inert material (e.g. dry sand or earth), then place in a chemical waste container.
After removal, ventilate contaminated area and flush thoroughly with water.
7. Handling and Storage
Hazard Label Information: Avoid contact with skin and eyes. Do not reuse this container. Use with adequate ventilation.
Wash thoroughly after handling.
Precautions To Be Taken in Handling: Avoid breathing (dust, vapor, mist, gas).
Avoid contact with eyes, skin, and clothing.
Avoid prolonged or repeated exposure.
Do not reuse this container.
Keep away from sources of ignition.
Use with adequate ventilation.
Wash thoroughly after handling.
Precautions To Be Taken in Storing: Keep tightly closed.
Store at correct temperature.
8. Exposure Controls/Personal Protection
Protective Equipment Summary - Hazard Eye wash station in work area Lab coat Protective gloves Safety glasses Safety shower
Label Information: in work area Vent Hood
Respiratory Equipment (Specify Type): Government approved respirator as conditions warrant.
Eye Protection: Safety glasses
Protective Gloves: Use appropriate hand protection based on solvent.
Other Protective Clothing: Lab coat
Engineering Controls (Ventilation etc.): Use process enclosures, local exhaust ventilation, or other engineering controls to control airborne
levels below recommended exposure limits.
Work/Hygienic/Maintenance Practices: Do not take internally.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a
safety shower.
Wash thoroughly after handling.
ANSI Z400.1 Format
MATERIAL SAFETY DATA SHEET Page: 3
Printed: 10/24/2005
O-1918 Revision: 10/24/2005
9. Physical and Chemical Properties
Physical States: [ ] Gas [ X ] Liquid [ ] Solid
Melting Point: No data.
Boiling Point: No data.
Autoignition Pt: 502.00 C
Flash Pt: -10.00 C Method:
Explosive Limits: LEL: 3.1% at 25.0 C UEL: 16% at 25.0 C
Specific Gravity (Water = 1): No data.
Vapor Pressure (vs. Air or mm Hg): 165 MM_HG at 20.0 C
Vapor Density (vs. Air = 1): No data.
Evaporation Rate (vs Butyl Acetate=1): No data.
Solubility in Water: 0.5 mg/ml* at 25.0 C
Other Solubility Notes: *Ethanol:PBS pH 7.2 (1:1), sol. in EtOH, DMSO, & DMF
Percent Volatile: No data.
Corrosion Rate: No data.
Formula: C19H26O2
Molecular Weight: 286.40
pH: No data.
Appearance and Odor: A clear, colorless solution
10. Stability and Reactivity
Stability: Unstable [ ] Stable [ X ]
Conditions To Avoid - Instability: protect from moisture
Incompatibility - Materials To Avoid: strong oxidizing agents
Hazardous Decomposition Or Byproducts: carbon dioxide
carbon monoxide
Hazardous Polymerization: Will occur [ ] Will not occur [ X ]
Conditions To Avoid - Hazardous No data available.
Polymerization:
11. Toxicological Information
Toxicological Information: The toxicological effects of this compound have not been thoroughly studied.
Methyl Acetate - Toxicity Data:
Oral LD50 (rat): > 5000 mg/kg
Oral LD50 (rabbit): 3705 mg/kg
Skin LD50 (rabbit): > 5000 mg/kg
Methyl Acetate - Irritation Data:
Skin (rabbit): 500 mg 24H mild effect
Skin (rabbit): 20 mg 24H moderate effect
Eyes (rabbit): 100 mg 24H moderate effect
Chronic Toxicological Effects: Methyl Acetate - Investigated as a tumorigen, mutagen, and reproductive effector.
Only select Registry of Toxic Effects of Chemical Substances (RTECS) data is presented here.
See actual entry in RTECS for complete information.
Methyl Acetate RTECS Number: AI9100000
Carcinogenicity/Other Information: No data available.
Carcinogenicity: NTP? No IARC Monographs? No OSHA Regulated? No
ANSI Z400.1 Format
MATERIAL SAFETY DATA SHEET Page: 4
Printed: 10/24/2005
O-1918 Revision: 10/24/2005
12. Ecological Information
Ecological Information: Runoff from fire control or dilution water may cause pollution.
13. Disposal Considerations
Waste Disposal Method: Dispose in accordance with local, state, and federal regulations.
14. Transport Information
LAND TRANSPORT (US DOT)
DOT Proper Shipping Name: Methyl acetate
DOT Hazard Class: 3
DOT Hazard Label: FLAMMABLE LIQUID
UN/NA Number: 1231
DOT Packing Group: II
Additional Transport Information: Transport in accordance with local, state, and federal regulations.
15. Regulatory Information
US EPA SARA Title III
Hazardous Components (Chemical Name) CAS # Sec.302 (EHS) Sec.304 RQ Sec.313 (TRI) Sec.110
1. O-1918 536697-79-7 No No No No
2. Methyl acetate 79-20-9 No No No No
US EPA CAA, CWA, TSCA
Hazardous Components (Chemical Name) CAS # EPA CAA EPA CWA NPDES EPA TSCA CA PROP 65
1. O-1918 536697-79-7 No No No No
2. Methyl acetate 79-20-9 No No 8A PAIR ,8D No
16. Other Information
Company Policy or Disclaimer
For research use only, not for human or veterinary clinical use.
DISCLAIMER: This information is believed to be accurate and represents the best information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should
make their own investigations to determine the suitability of the information for their particular purposes.
ANSI Z400.1 Format
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