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MSDS Material Safety Data Sheet
CAS

67-66-3

File Name: spectrumchemical_com---c4050.asp
                                                                                   Material Safety Data Sheet
HMIS
NFPA Personal Protective Equipment

Health Hazard
2
0 Fire Hazard
0
2 0
Reactivity
0 See Section 15.


Section 1. Chemical Product and Company Identification Page Number: 1

Chloroform Catalog C3029, C1220, SP125, C1121,
Common Name/
Number(s). HS200, C1222
Trade Name

67-66-3
CAS#
Manufacturer
FS9100000
SPECTRUM LABORATORY PRODUCTS INC. RTECS
14422 S. SAN PEDRO STREET T S CA 8 (b ) i n v e n t o ry :
TSCA
GARDENA, CA 90248 Chloroform

Not available.
Commercial Name(s)
Not available.
CI#
Trichloromethane; Methane, trichlor-
Synonym
IN CASE OF EMERGENCY
CHEMTREC (24hr) 800-424-9300
Chloroform
Chemical Name

Not available. CALL (310) 516-8000
Chemical Family

CHCl3
Chemical Formula

SPECTRUM LABORATORY PRODUCTS INC.
Supplier
14422 S. SAN PEDRO STREET
GARDENA, CA 90248


Section 2.Composition and Information on Ingredients
Exposure Limits

TWA (mg/m3) STEL (mg/m3) CEIL (mg/m3)
Name CAS # % by Weight

1) Chloroform 67-66-3 2 9.78 100



Chloroform:
Toxicological Data
ORAL (LD50): Acute: 695 mg/kg [Rat]. 36 mg/kg [Mouse]. 820 mg/kg [Guinea pig].
on Ingredients
DERMAL (LD50): Acute: >20000 mg/kg [Rabbit].
Acute: 47702 mg/m3 4 hours [Rat].
VAPOR (LC50):


Section 3. Hazards Identification
Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Slightly hazardous in
Potential Acute Health
case of skin contact (permeator).
Effects

CARCINOGENIC EFFECTS: Classified + (Proven.) by NIOSH. Classified A3 (Proven for animal.) by ACGIH, 2B
Potential Chronic Health
(Possible for human.) by IARC. Classified 2 (Some evidence.) by NTP.
Effects
MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
The substance may be toxic to kidneys, liver, heart.
Repeated or prolonged exposure to the substance can produce target organs damage.

Continued on Next Page
Page Number: 2
Chloroform

Section 4. First Aid Measures
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least
Eye Contact
15 minutes. Cold water may be used. WARM water MUST be used. Get medical attention.

In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove
Skin Contact
contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical
attention.

Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate
Serious Skin Contact
medical attention.

If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
Inhalation
medical attention.

Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband.
Serious Inhalation
If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation.
WARNING: It may be hazardous to the person providing aid to give mouth-to-mouth resuscitation when the inhaled
material is toxic, infectious or corrosive. Seek medical attention.

Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
Ingestion
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
clothing such as a collar, tie, belt or waistband.

Not available.
Serious Ingestion



Section 5. Fire and Explosion Data
Flammability of the Product Non-flammable.

Not applicable.
Auto-Ignition Temperature

Not applicable.
Flash Points

Not applicable.
Flammable Limits

Not available.
Products of Combustion

Fire Hazards in Presence of Not applicable.
Various Substances

Risks of explosion of the product in presence of mechanical impact: Not available.
Explosion Hazards in
Risks of explosion of the product in presence of static discharge: Not available.
Presence of Various
Substances

Not applicable.
Fire Fighting Media
and Instructions

Not available.
Special Remarks on
Fire Hazards

May expl ode i f i t comes i n contact wi th al umi num powder, l i thi um, perchl orate, pentoxi de,
Special Remarks on
bis(dimethylamino)dimethylstannane, potassium, potassium-sodium alloy, sodium (or sodium hydroxide or sodium
Explosion Hazards
methoxide), and methanol

Section 6. Accidental Release Measures
Absorb with an inert material and put the spilled material in an appropriate waste disposal.
Small Spill

Absorb with an inert material and put the spilled material in an appropriate waste disposal. Be careful that the
Large Spill
product is not present at a concentration level above TLV. Check TLV on the MSDS and with local authorities.




Continued on Next Page
Page Number: 3
Chloroform

Section 7. Handling and Storage
Do not ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable protective clothing. In case of insufficient
Precautions
ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the
container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such as metals, alkalis.
Keep container tightly closed. Keep container in a cool, well-ventilated area. Sensitive to light. Store in
Storage
light-resistant containers.

Section 8. Exposure Controls/Personal Protection
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
Engineering Controls
respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station
location.

Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection


Personal Protection in Case Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to
avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE
of a Large Spill
handling this product.

TWA: 10 (ppm) [Australia] Inhalation
Exposure Limits
TWA: 2 (ppm) from OSHA (PEL) [United States] Inhalation
STEL: 9.78 (mg/m3) from NIOSH Inhalation
STEL: 2 (ppm) from NIOSH Inhalation
TWA: 9.78 (mg/m3) from OSHA (PEL) [United States] Inhalation
TWA: 10 (ppm) from ACGIH (TLV) [United States] [1999] Inhalation
TWA: 2 (ppm) [United Kingdom (UK)] Inhalation
TWA: 9.9 (mg/m3) [United Kingdom (UK)] Inhalation

Consult local authorities for acceptable exposure limits.

Section 9. Physical and Chemical Properties
Liquid. Pleasant. Etheric.
Physical state and Odor
appearance
Sweet.
Taste
119.38 g/mole
Molecular Weight
Colorless. Clear
Color
Not available.
pH (1% soln/water)

61掳 (141.8掳
C F)
Boiling Point

-63.5掳 (-82.3掳
C F)
Melting Point

263.33掳 (506掳
C F)
Critical Temperature

1.484 (Water = 1)
Specific Gravity

21.1 kPa (@ 20掳
C)
Vapor Pressure

4.36 (Air = 1)
Vapor Density

Not available.
Volatility

85 ppm
Odor Threshold

The product is more soluble in oil; log(oil/water) = 2
Water/Oil Dist. Coeff.

Not available.
Ionicity (in Water)

Not available.
Dispersion Properties

Very slightly soluble in cold water.
Solubility




Continued on Next Page
Page Number: 4
Chloroform

Section 10. Stability and Reactivity Data
The product is stable.
Stability

Not available.
Instability Temperature

Incompatible materials, Light
Conditions of Instability

Incompatibility with various Reactive with metals, alkalis.
substances

Non-corrosive in presence of glass.
Corrosivity


Light Sensitive. Incompatible with triisopropyl phosphine, acetone, disilane, fluorine, strong bases and reactive
Special Remarks on
metals (aluminum, magnesium in powdered form), light.
Reactivity

It will attack some forms of plastics, rubber, and coatings.
Special Remarks on
Corrosivity
Will not occur.
Polymerization


Section 11. Toxicological Information
Absorbed through skin. Eye contact. Inhalation.
Routes of Entry

WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE.
Toxicity to Animals
Acute oral toxicity (LD50): 36 mg/kg [Mouse].
Acute dermal toxicity (LD50): >20000 mg/kg [Rabbit].
Acute toxicity of the vapor (LC50): 47702 mg/m3 4 hours [Rat].

CARCINOGENIC EFFECTS: Classified + (Proven.) by NIOSH. Classified A3 (Proven for animal.) by ACGIH, 2B
Chronic Effects on Humans
(Possible for human.) by IARC. Classified 2 (Some evidence.) by NTP.
MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast.
May cause damage to the following organs: kidneys, liver, heart.

Hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Other Toxic Effects on
Slightly hazardous in case of skin contact (permeator).
Humans

Not available.
Special Remarks on
Toxicity to Animals

May affect genetic material (possible mutangen) and cause adverse reproductive effects(embryotoxicity and
Special Remarks on
fetotoxicity) Suspected carcinogen (tumorigenic) and teratogen based on animal data.
Chronic Effects on Humans
Human: passes the placental barrier, detected in maternal milk.

Acute Potential Health Effects:
Special Remarks on other
Skin: Causes skin irritation and may cause chemical burns.
Toxic Effects on Humans
Eye: Causes eye irritation, burning pain and reversible injury to corneal epithelium.
Inhalation: Causes irritation of the respiratory system (mucous membranes). May affect behavior/Nervous system
(CNS depressant, fatigue, dizziness, nervousness, giddiness, euphoria, loss of coordination and judgement, weakness,
hallucinations, muscle contraction/spasticity, general anesthetic, spastic paralysis, headache), anorexia (neurological
and gastrointestinal symtoms resembling chronic alcoholism), and possibly coma and death. May affect the liver,
kidneys and gastrointestinal tract (nausea, vomiting).
Ingestion: Causes gastrointestinal tract irritation (nausea, vomiting). May affect the liver, urinary system (kidneys),
respiration, behavior/nervous system (symptoms similar to inhalation),and heart.
Chronic Potential Health Effects:
Inhalation: Prolonged or repeated inhalation may affect the liver (hepatitis, jaundice, hepatocellular necrosis),
metabolism (weight loss), respiration (fibrosis, pneumoconoisis), behavior/central nervous system (symptoms similar to
acute inhalation), blood, musculoskeletal system, and kidneys.
Ingestion: Prolonged or repeated ingestion may affect the liver, kidneys, metabolism (weight loss), endocrine system
(spleen), blood (changes in cell count).




Continued on Next Page
Page Number: 5
Chloroform

Section 12. Ecological Information
Ecotoxicity in water (LC50): 43.8 mg/l 96 hours [Trout].
Ecotoxicity

Not available.
BOD5 and COD

Possibly hazardous short term degradation products are not likely. However, long term degradation products may
Products of Biodegradation
arise.

The products of degradation are as toxic as the product itself.
Toxicity of the Products
of Biodegradation

Not available.
Special Remarks on the
Products of Biodegradation

Section 13. Disposal Considerations
Waste must be disposed of in accordance with federal, state and local environmental control
Waste Disposal
regulations.


Section 14. Transport Information
CLASS 6.1: Poisonous material.
DOT Classification

UNNA: 1888 : Chloroform PG: III
Identification


Not available.
Special Provisions for
Transport

DOT (Pictograms)




Section 15. Other Regulatory Information and Pictograms
California prop. 65: This product contains the following ingredients for which the State of California has found to
Federal and State
cause cancer, birth defects or other reproductive harm, which would require a warning under the statute: Chloroform
Regulations
California prop. 65 (no significant risk level): Chloroform: 0.02 mg/day (value)
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause cancer which would require a warning under the statute: Chloroform
Connecticut hazardous material survey.: Chloroform
Illinois toxic substances disclosure to employee act: Chloroform
Illinois chemical safety act: Chloroform
New York release reporting list: Chloroform
Rhode Island RTK hazardous substances: Chloroform
Pennsylvania RTK: Chloroform
Minnesota: Chloroform
Michigan critical material: Chloroform
Massachusetts RTK: Chloroform
Massachusetts spill list: Chloroform
New Jersey: Chloroform
New Jersey spill list: Chloroform
New Jersey toxic catastrophe prevention act: Chloroform
Louisiana RTK reporting list: Chloroform
Louisiana spill reporting: Chloroform
California Director's List of Hazardous Subtances (8 CCR 339): Chloroform
TSCA 8(b) inventory: Chloroform
TSCA 8(d) H and S data reporting: Chloroform: effective: 6/1/87; sunset: 6/1/97
SARA 302/304/311/312 extremely hazardous substances: Chloroform
SARA 313 toxic chemical notification and release reporting: Chloroform
CERCLA: Hazardous substances.: Chloroform: 10 lbs. (4.536 kg)




Continued on Next Page
Page Number: 6
Chloroform
California prop. 65: This product contains the following ingredients for which the State of California has found to
California
cause cancer which would require a warning under the statute: Chloroform
Proposition 65
Warnings California prop. 65: This product contains the following ingredients for which the State of California has found to
cause birth defects which would require a warning under the statute: No products were found.

OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
Other Regulations
EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS No.
200-663-8).
Canada: Listed on Canadian Domestic Substance List (DSL).
China: Listed on National Inventory.
Japan: Listed on National Inventory (ENCS).
Korea: Listed on National Inventory (KECI).
Philippines: Listed on National Inventory (PICCS).
Australia: Listed on AICS.

CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
Other Classifications WHMIS (Canada)
CLASS D-2A: Material causing other toxic effects (VERY TOXIC).
Class D-2B: Material causing other toxic effects (TOXIC).

R22- Harmful if swallowed. S36/37- Wear suitable protective clothing and
DSCL (EEC)
R38- Irritating to skin. gloves.
R40- Limited evidence of carcinogenic
effect.
R48/20/22- Harmful: danger of serious
damage to health by prolonged
exposure through inhalation and if
swallowed.

Health Hazard
HMIS (U.S.A.) 2 National Fire Protection Flam ability
m
0
Association (U.S.A.)
Fire Hazard
0
2 0
Health Reactivity
Reactivity
0
Specific hazard
Personal Protection
h

WHMIS (Canada)
(Pictograms)



DSCL (Europe)
(Pictograms)



TDG (Canada)
(Pictograms)



ADR (Europe)
(Pictograms)



Protective Equipment Gloves.



Lab coat.




Continued on Next Page
Page Number: 7
Chloroform
Vapor respirator. Be sure to use an
approved/certified respirator or equivalent.
Wear appropriate respirator when ventilation
is inadequate.
Splash goggles.




Section 16. Other Information
C4050
MSDS Code

Not available.
References
Other Special
Not available.
Considerations

Validated by Sonia Owen on 6/2/2008. Verified by Sonia Owen.
Printed 6/26/2008.

CALL (310) 516-8000


Notice to Reader
All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is combined with other materials,
deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper methods of handling and personal protection based on the actual
conditions of use. While this MSDS is based on technical data judged to be reliable, SpectrumQuality Products, Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.

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