**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 62-53-3 |Aniline | ca. 100 | 200-539-3 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T N
Risk Phrases: 20/21/22 40 48/23/24/25
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed.
Possible risks of irreversible effects. Toxic : danger of serious
damage to health by prolonged exposure through inhalation, contact
with skin and if swallowed.Combustible liquid.Hygroscopic.Light
sensitive.Dangerous for the environment.
Potential Health Effects
Eye:
Causes severe eye irritation. May cause lacrimation (tearing),
blurred vision, and photophobia. May cause chemical conjunctivitis
and corneal damage.
Skin:
Causes moderate skin irritation. Harmful if absorbed through the
skin. May cause skin sensitization, an allergic reaction, which
becomes evident upon re-exposure to this material.
Ingestion:
Harmful if swallowed. Causes gastrointestinal irritation with
nausea, vomiting and diarrhea. May cause effects similar to those of
acute inhalation. May cause central nervous system depression,
convulsions, coma, and possible death due to respiratory paralysis.
May cause cardiac effects such as heart blocks, arrhythmias, shock
and possible death due to cardiovascular collapse.
Inhalation:
Effects may be delayed. Causes respiratory tract irritation. May
cause methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea
(labored breathing), and death. Aspiration may lead to pulmonary
edema.
Chronic:
May cause liver and kidney damage. May cause fetal effects. Repeated
exposure may cause sensitization dermatitis. Chronic exposure may
cause hemolysis of the red blood cells followed by stimulation of the
bone marrow. Laboratory experiments have resulted in mutagenic
effects. May cause cyanosis - a blue-gray coloring of the skin and
lips caused by a lack of oxygen. Animal studies have reported the
development of tumors.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid. Do
NOT allow victim to rub or keep eyes closed.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
soap and water for at least 15 minutes while removing contaminated
clothing and shoes. Wash clothing before reuse. Destroy contaminated
shoes.
Ingestion:
Do NOT induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air
immediately. If breathing is difficult, give oxygen. Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply
artificial respiration using oxygen and a suitable mechanical device
such as a bag and a mask.
Notes to Physician:
Absorption of this product into the body may cause cyanosis (bluish
discoloration of skin due to deficient oxygenation of the blood).
Moderate degrees of cyanosis need to be treated only by supportive
measures: bed rest and oxygen inhalation. Cleansing of the entire
contaminated area of the body is of utmost importance. Do not
administer alcohol in any form. Individuals with liver or kidney
disorders, impaired cardiovascular status, or a history of
alcoholism may be more susceptible to the effects of this product.
Effects may be delayed. If cyanosis is severe, intravenous injection
of Methylene blue, 1mg/kg of body weight may be of value.
Antidote:
Methylene blue, alone or in combination with oxygen is indicated as
a treatment in nitrite induced methemoglobinemia.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Water runoff can cause environmental damage. Dike
and collect water used to fight fire. Use water spray to keep
fire-exposed containers cool. Combustible Liquid. Containers may
explode when heated.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam. Use water spray to cool fire-exposed
containers. Use extinguishing media most appropriate for the
surrounding fire.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Remove all sources of ignition. Use
a spark-proof tool. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Wash hands before eating. Remove
contaminated clothing and wash before reuse. Do not breathe dust,
vapor, mist, or gas. Do not get in eyes, on skin, or on clothing.
Empty containers retain product residue, (liquid and/or vapor), and
can be dangerous. Keep container tightly closed. Avoid contact with
heat, sparks and flame. Do not ingest or inhale. Store protected from
light. Use only in a chemical fume hood. Do not pressurize, cut,
weld, braze, solder, drill, grind, or expose empty containers to
heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Store in a tightly closed container. Keep from contact
with oxidizing materials. Store in a cool, dry, well-ventilated area
away from incompatible substances. Poison room locked. Keep away
from acids. Material darkens in color on storage. Store protected
from moisture. Store protected from light.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits. Use only under a chemical fume hood.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR ??1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant a respirator's use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Appearance: oily liquid - colorless liquid
Odor: amine-like - characteristic odor
pH: 8.1
Vapor Pressure: 0.49 mm Hg @ 20 deg C
Viscosity: 4.435 cp @ 20 deg C
Boiling Point: 184 deg C @ 760.00 mmHg
Freezing/Melting Point: -6 deg C
Autoignition Temperature: 615 deg C ( 1,139.00 deg F)
Flash Point: 70 deg C ( 158.00 deg F)
Explosion Limits, lower: 1.30 vol %
Explosion Limits, upper: 20.00 vol %
Decomposition Temperature:
Solubility in water: IN WATER: 0.3 G/L (20C)
Specific Gravity/Density: 1.0216g/cm3
Molecular Formula: C6H7N
Molecular Weight: 93.13
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures. Volatile in steam.
Sensitive to light. May discolor on exposure to air and light.
Conditions to Avoid:
Incompatible materials, light, ignition sources, excess heat,
exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, bases, aluminum, fluorine,
formaldehyde, iron, nitric acid, silver perchlorate, sodium peroxide,
sulfuric acid, zinc, hydrogen peroxides, ozone, acid anhydrides,
chlorosulfonic acid, oleum, perchromates, nitromethane, dibenzoyl
peroxide, benzenediazonium-2-carboxylate, boron trichloride,
tetranitromethane, trichloronitromethane, diisopropyl
peroxydicarbonate, hexachloromelamine, peroxomonosulfuric acid,
albumin, iron salts, perchloric acid, nitrobenzene, alkalis,
moisture, potassium peroxide, glycerine, fuming nitric acid,
N-chloro compounds, N-bromoimides (e.g. n-bromosuccinimide),
peroxydisulfuric acid, nitrosyl fluoride, toluene diisocyanate.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 62-53-3: BW6650000
LD50/LC50:
CAS# 62-53-3: Dermal, guinea pig: LD50 = 1290 mg/kg; Draize test,
rabbit, eye: 102 mg Severe; Draize test, rabbit, eye: 20 mg/24H
Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation,
mouse: LC50 = 175 ppm/7H; Oral, mouse: LD50 = 464 mg/kg; Oral, rat:
LD50 = 250 mg/kg; Skin, rabbit: LD50 = 820 uL/kg; Skin, rat: LD50 =
1400 mg/kg.
Carcinogenicity:
Aniline -
ACGIH: A3 - Animal Carcinogen
California: carcinogen; initial date 1/1/90
NIOSH: occupational carcinogen
IARC: Group 3 carcinogen
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Bacteria: Phytobacterium phosphoreum: EC50 = 425-488 mg/L; 5,15 min;
Microtox test at 14.9-15.1CWater flea Daphnia: LC50 = 0.10 mg/L; 48
Hr; UnspecifiedFish: Rainbow trout: LC50 = 8.2 mg/L; Max. exposure =
7 days; UnspecifiedFish: Bluegill/Sunfish: 1020 ppm; 1 Hr;
Unspecified
Other
Dangerous to aquatic life in high concentrations.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: ANILINE
Hazard Class: 6.1
UN Number: 1547
Packing Group: II
IMO
Shipping Name: ANILINE
Hazard Class: 6.1
UN Number: 1547
Packing Group: II
RID/ADR
Shipping Name: ANILINE
Dangerous Goods Code: 6.1(12B)
UN Number: 1547
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 40 Possible risks of irreversible effects.
R 48/23/24/25 Toxic : danger of serious damage to
health by prolonged exposure through inhalation,
contact with skin and if swallowed.
Safety Phrases:
S 28 After contact with skin, wash immediately
with...
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/Safety data sheets.
WGK (Water Danger/Protection)
CAS# 62-53-3: 2
United Kingdom Occupational Exposure Limits
Canada
CAS# 62-53-3 is listed on Canada's DSL List.
CAS# 62-53-3 is listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 62-53-3: OEL-ARAB Republic of Egypt:TWA 2 ppm (10 mg/m3);Skin
OEL-AUSTRALIA:TWA 2 ppm (10 mg/m3);Skin
OEL-AUSTRIA:TWA 2 ppm (8 mg/m3);Skin
OEL-BELGIUM:TWA 2 ppm (7.6 mg/m3);Skin
OEL-CZECHOSLOVAKIA:TWA 5 mg/m3;STEL 20 mg/m3 JAN9
OEL-DENMARK:TWA 1 ppm (4 mg/m3);Skin
OEL-FINLAND:TWA 2 ppm (7.6 mg/m3);STEL 4 ppm (15 mg/m3);Skin;CAR
OEL-FRANCE:TWA 2 ppm (10 mg/m3);Skin
OEL-GERMANY:TWA 2 ppm (8 mg/m3);Skin;Carcinogen
OEL-HUNGARY:TWA 5 mg/m3;STEL 10 mg/m3;Skin
OEL-INDIA:TWA 0.2 mg/m3;Skin
OEL-JAPAN:TWA 1 ppm (3.8 mg/m3);Skin
OEL-THE NETHERLANDS:TWA 5 ppm (19 mg/m3);Skin
OEL-THE PHILIPPINES:TWA 5 ppm (19 mg/m3);Skin
OEL-POLAND:TWA 5 mg/m3;STEL 20 mg/m3;Skin
OEL-RUSSIA:TWA 1 ppm;STEL 0.1 mg/m3;Skin
OEL-SWEDEN:TWA 1 ppm (4 mg/m3);STEL 2 ppm (8 mg/m3);Skin
OEL-SWITZERLAND:TWA 2 ppm (8 mg/m3);STEL 10 ppm (40 mg/m3);Skin
OEL-TURKEY:TWA 5 ppm (19 mg/m3);Skin
OEL-UNITED KINGDOM:TWA 2 ppm (10 mg/m3);STEL 5 ppm;Skin
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
US FEDERAL
TSCA
CAS# 62-53-3 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 6/04/1999 Revision #2 Date: 8/02/2000
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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