**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 64-17-5 |Ethyl alcohol | 0.75 | 200-578-6 |
|----------------|--------------------------------------|----------|-----------|
| 67-66-3 |Chloroform | 99+ | 200-663-8 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: XN
Risk Phrases: 22 38 40 48/20/22
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful if swallowed. Irritating to skin. Limited evidence of a
carcinogenic effect. Harmful : danger of serious damage to health by
prolonged exposure through inhalation and if swallowed.Light
sensitive.
Potential Health Effects
Eye:
Causes moderate eye irritation. Contact with liquid causes
immediate burning pain, tearing, and reddening of the conjunctiva.
Skin:
Causes mild skin irritation. May be absorbed through the skin in
harmful amounts. May cause severe skin irritation with possible
burns, especially if skin is wet or moist.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and
diarrhea. May cause liver damage. May cause cardiac disturbances.
Aspiration of material into the lungs may cause chemical pneumonitis,
which may be fatal. Possible aspiration hazard. May be harmful if
swallowed. May cause hallucinations and distorted perceptions.
Inhalation:
Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness
and coma. May cause cardiac sensitization and possible failure.
Inhalation of large amounts may cause respiratory stimulation,
followed by respiratory depression, convulsions and possible death
due to respiratory paralysis. May be absorbed through the lungs.
Causes irritation of the mucous membrane and upper respiratory
tract.
Chronic:
Possible cancer hazard based on tests with laboratory animals.
Prolonged or repeated skin contact may cause defatting and
dermatitis. May cause reproductive and fetal effects. Effects may be
delayed. Laboratory experiments have resulted in mutagenic effects.
Toxicity may be increased by exposure to alcohol, steroids, and
ketones. Prolonged exposure may cause liver, kidney, and heart
damage.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen.
Notes to Physician:
Causes cardiac sensitization to endogenous catelcholamines which may
lead to cardiac arrhythmias. Do NOT use adrenergic agents such as
epinephrine or pseudoepinephrine. Persons with liver, kidney, or
central nervous system diseases may be at increased risk from
exposure to this product. Alcoholic beverage consumption may enhance
the toxic effects of this substance. Effects may be delayed.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Use water
spray to keep fire-exposed containers cool. Substance is
nonflammable. Vapors may be heavier than air. They can spread along
the ground and collect in low or confined areas. Containers may
explode when heated. Non-combustible, substance itself does not burn
but may decompose upon heating to produce corrosive and/or toxic
fumes. Non-combustible, substance itself does not burn but may
decompose upon heating to produce irritating, corrosive and/or toxic
fumes. Approach fire from upwind to avoid hazardous vapors and toxic
decomposition products. Not combustible, but if involved in a fire,
decomposes to produce hydrogen chloride.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Clean up spills immediately,
observing precautions in the Protective Equipment section. Provide
ventilation. Approach spill from upwind.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Avoid contact
with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or
gas. Do not ingest or inhale. Store protected from light.
Storage:
Do not store in direct sunlight. Store in a cool, dry,
well-ventilated area away from incompatible substances. Keep away
from acids. Do not store near alkaline substances. Separate from
strong mineral acids.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
CAS# 64-17-5:
United Kingdom, WEL - TWA: 1000 ppm TWA; 1920 mg/m3 TWA
United Kingdom, WEL - STEL: 3000 ppm STEL; 5760 mg/m3 STEL
United States OSHA: 1000 ppm TWA; 1900 mg/m3 TWA
Belgium - TWA: 1000 ppm VLE; 1907 mg/m3 VLE
France - VME: 1000 ppm VME; 1900 mg/m3 VME
France - VLE: 5000 ppm VLE; 9500 mg/m3 VLE
Germany: 500 ppm TWA; 960 mg/m3 TWA
Malaysia: 1000 ppm TWA; 1880 mg/m3 TWA
Netherlands: 500 ppm MAC; 1000 mg/m3 MAC
Russia: 1000 mg/m3 TWA
Spain: 1000 ppm VLA-ED; 1910 mg/m3 VLA-ED
CAS# 67-66-3:
United Kingdom, WEL - TWA: 2 ppm TWA; 9.9 mg/m3 TWA
United Kingdom, WEL - STEL: 6 ppm STEL; 29.7 mg/m3 STEL
United States OSHA: ; 50 ppm Ceiling; 240 mg/m3 Ceiling
Belgium - TWA: 10 ppm VLE; 50 mg/m3 VLE
France - VME: 5 ppm VME; 25 mg/m3 VME
France - VLE: 50 ppm VLE; 250 mg/m3 VLE
Germany: 4 ppm TWA (large technical manufacture and use); 20 mg/m
TWA (large technical m
Germany: Skin absorber
Japan: 10 ppm OEL; 49 mg/m3 OEL
Malaysia: 10 ppm TWA; 49 mg/m3 TWA
Netherlands: 5 ppm STEL; 25 mg/m3 STEL
Netherlands: 1 ppm MAC; 5 mg/m3 MAC
Spain: 2 ppm VLA-ED; 10 mg/m3 VLA-ED
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: clear, colorless
Odor: sweet, fruity odor - ethereal odor
pH: Not available.
Vapor Pressure: 160 mm Hg @ 20 deg C
Viscosity: 0.58 cps @ 20 deg C
Boiling Point: 60.5-61.5 deg C
Freezing/Melting Point: -63 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Slightly soluble.
Specific Gravity/Density: 1.492 (Water=1)
Molecular Formula: CHCl3
Molecular Weight: 119.366
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions. Light sensitive.
Conditions to Avoid:
High temperatures, incompatible materials, light.
Incompatibilities with Other Materials:
Alkali metals, fluorine, caustics (e.g. ammonia, ammonium hydroxide,
calcium hydroxide, potassium hydroxide, sodium hydroxide),
dinitrogen tetraoxide, sodium hydroxide + methanol, potassium
tert-butoxide, chemically active metals, powdered aluminum, nitrogen
tetroxide, powdered magnesium, acetone + alkali, disilane,
perchloric acid + phosphorus pentoxide, sodium methylate,
triisopropylphosphine.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide, chlorine,
phosgene gas.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 64-17-5: KQ6300000
CAS# 67-66-3: FS9100000
LD50/LC50:
CAS# 64-17-5: Draize test, rabbit, eye: 500 mg Severe; Draize test,
rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, skin: 20 mg/24H
Moderate; Inhalation, mouse: LC50 = 39 gm/m3/4H; Inhalation, rat:
LC50 = 20000 ppm/10H; Oral, mouse: LD50 = 3450 mg/kg; Oral, rabbit:
LD50 = 6300 mg/kg; Oral, rat: LD50 = 7060 mg/kg; Oral, rat: LD50 =
9000 mg/kg.
CAS# 67-66-3: Draize test, rabbit, eye: 148 mg; Draize test, rabbit,
eye: 20 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/24H Mild;
Inhalation, mouse: LC50 = 17200 mg/m3/2H; Inhalation, mouse: LC50 =
6000 mg/m3/6H; Inhalation, rat: LC50 = 47702 mg/m3/4H; Inhalation,
rat: LC50 = 6000 mg/m3/6H; Oral, mouse: LD50 = 36 mg/kg; Oral, rat:
LD50 = 695 mg/kg; Oral, rat: LD50 = 1250 mg/kg; Skin, rabbit: LD50 =
>20 gm/kg.
Carcinogenicity:
Ethyl alcohol -
Not listed by ACGIH, IARC, or NTP.
Chloroform -
ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to
California: carcinogen, initial date 10/1/87
NTP: Suspect carcinogen
IARC: Group 2B carcinogen
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Fish: Channel catfish: LC50 = 75 ppm; 96 Hr; UnspecifiedFish: Rainbow
trout: LC50 = 43.8 mg/L; 96 Hr; Static bioassayFish: Fathead Minnow:
LC50 = 129.0 mg/L; 96 Hr; Static bioassay (pH = 7.6-8.3)Fish:
Bluegill/Sunfish: LC50 = 100.0 mg/L; 96 Hr; Static bioassayWater
flea Daphnia: EC50 = 28.9 mg/L; 48 Hr; Static bioassayThe majority of
the environmental releases from industrial uses are to the
atmosphere; releases to water and land will be primarily lost by
evaporation and will end up in the atmosphere. Release to the
atmosphere may be transported long distances and will photodegrade
with a half-life of a
few months. Spills and other releases on land
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: CHLOROFORM
Hazard Class: 6.1
UN Number: 1888
Packing Group: III
IMO
Shipping Name: CHLOROFORM
Hazard Class: 6.1
UN Number: 1888
Packing Group: III
RID/ADR
Shipping Name: CHLOROFORM
Hazard Class: 6.1
UN Number: 1888
Packing group: III
USA RQ: CAS# 67-66-3: 10 lb final RQ; 4.54 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
R 38 Irritating to skin.
R 40 Limited evidence of a carcinogenic effect.
R 48/20/22 Harmful : danger of serious damage to
health by prolonged exposure through inhalation and if
swallowed.
Safety Phrases:
S 36/37 Wear suitable protective clothing and
gloves.
WGK (Water Danger/Protection)
CAS# 64-17-5: 0
CAS# 67-66-3: 3
Canada
CAS# 64-17-5 is listed on Canada's DSL List.
CAS# 67-66-3 is listed on Canada's DSL List.
CAS# 64-17-5 is listed on Canada's Ingredient Disclosure List.
CAS# 67-66-3 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 64-17-5 is listed on the TSCA inventory.
CAS# 67-66-3 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
R 11 Highly flammable.
MSDS Creation Date: 6/09/1999 Revision #8 Date: 4/13/2004
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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