**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 67-63-0 |Isopropanol | ca 100 | 200-661-7 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: XI F
Risk Phrases: 11 36 67
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Highly flammable. Irritating to eyes. Vapors may cause drowsiness
and dizziness.Hygroscopic.
Potential Health Effects
Eye:
Produces irritation, characterized by a burning sensation, redness,
tearing, inflammation, and possible corneal injury. May cause
transient corneal injury.
Skin:
May cause irritation with pain and stinging, especially if the skin
is abraded. Isopropanol has a low potential to cause allergic skin
reactions; however, rare cases of allergic contact dermatitis have
been reported. May be absorbed through intact skin.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and
diarrhea. May cause kidney damage. May cause central nervous system
depression, characterized by excitement, followed by headache,
dizziness, drowsiness, and nausea. Advanced stages may cause
collapse, unconsciousness, coma and possible death due to
respiratory failure. Aspiration of material into the lungs may cause
chemical pneumonitis, which may be fatal.
Inhalation:
Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness
and coma. May cause narcotic effects in high concentration. Causes
upper respiratory tract irritation. Inhalation of vapors may cause
drowsiness and dizziness.
Chronic:
Prolonged or repeated skin contact may cause defatting and
dermatitis.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove
contaminated clothing and shoes. Get medical aid if irritation
develops and persists. Wash clothing before reuse.
Ingestion:
Potential for aspiration if swallowed. Get medical aid immediately.
Do not induce vomiting unless directed to do so by medical
personnel. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Urine acetone test may be helpful in diagnosis. Hemodialysis should
be considered in severe intoxication. Treat symptomatically and
supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors may form an explosive mixture with air. Use
water spray to keep fire-exposed containers cool. Flammable liquid
and vapor. May form explosive peroxides. Vapors are heavier than air
and may travel to a source of ignition and flash back. Vapors can
spread along the ground and collect in low or confined areas.
Extinguishing Media:
Water may be ineffective. Do NOT use straight streams of water. For
large fires, use dry chemical, carbon dioxide, alcohol-resistant
foam, or water spray. For small fires, use carbon dioxide, dry
chemical, dry sand, or alcohol-resistant foam. Cool containers with
flooding quantities of water until well after fire is out.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Use water spray to dilute spill to
a non-flammable mixture. Clean up spills immediately, observing
precautions in the Protective Equipment section. Remove all sources
of ignition. Use a spark-proof tool. Provide ventilation. A vapor
suppressing foam may be used to reduce vapors.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Ground and bond containers when transferring
material. Use spark-proof tools and explosion proof equipment. Avoid
contact with eyes, skin, and clothing. Empty containers retain
product residue, (liquid and/or vapor), and can be dangerous. Take
precautionary measures against static discharges. Keep container
tightly closed. Do not pressurize, cut, weld, braze, solder, drill,
grind, or expose empty containers to heat, sparks or open flames. Use
only with adequate ventilation. Avoid breathing vapor or mist. Do not
allow to evaporate to near dryness.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Do not store in direct sunlight. Store in a tightly closed
container. Keep from contact with oxidizing materials. Store in a
cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. After opening, purge container with nitrogen before
reclosing. Periodically test for peroxide formation on long-term
storage. Addition of water or appropriate reducing materials will
lessen peroxide formation. Store protected from moisture. Containers
should be dated when opened and tested periodically for the presence
of peroxides. Should crystals form in a peroxidizable liquid,
peroxidation may have occurred and the product should be considered
extremely dangerous. In this instance, the container should only be
opened remotely by professionals. All peroxidizable substances
should be stored away from heat and light and be protected from
ignition sources.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use explosion-proof ventilation equipment. Facilities storing or
utilizing this material should be equipped with an eyewash facility
and a safety shower. Use adequate general or local exhaust
ventilation to keep airborne concentrations below the permissible
exposure limits.
Personal Protective Equipment
Eyes:
Wear chemical goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR ??1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant a respirator's use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Appearance: colorless liquid
Odor: alcohol-like
pH: Not available.
Vapor Pressure: 33 mm Hg @ 20 deg C
Viscosity: 2.27 mPas @ 20C
Boiling Point: 82 deg C @ 760 mmHg
Freezing/Melting Point: -88 deg C
Autoignition Temperature: 399 deg C ( 750.20 deg F)
Flash Point: 12 deg C ( 53.60 deg F)
Explosion Limits, lower: 2.0 vol %
Explosion Limits, upper: 12.7 @ 200F
Decomposition Temperature: Not available.
Solubility in water: Miscible.
Specific Gravity/Density: 0.7850 (water=1)
Molecular Formula: C3H8O
Molecular Weight: 60.09
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Under normal storage conditions, peroxidizable compounds can form
and accumulate peroxides which may explode when subjected to heat or
shock. This material is most hazardous when peroxide levels are
concentrated by distillation or evaporation. Isopropanol is
susceptible to autoxidation and therefore should be classified as
peroxidizable.
Conditions to Avoid:
Light, ignition sources, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Attacks some forms of plastics, rubbers, and coatings., chlorine,
carbony dichloride(phosgene), acetaldehyde, ethylene oxide,
isocyanates, amines, aluminum at high temperatures, strong oxidizing
agents, strong acids, ammonia, strong bases.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 67-63-0: NT8050000
LD50/LC50:
CAS# 67-63-0: Draize test, rabbit, eye: 100 mg Severe; Draize test,
rabbit, eye: 10 mg Moderate; Draize test, rabbit, eye: 100 mg/24H
Moderate; Draize test, rabbit, skin: 500 mg Mild; Inhalation, rat:
LC50 = 16000 ppm/8H; Oral, mouse: LD50 = 3600 mg/kg; Oral, rabbit:
LD50 = 6410 mg/kg; Oral, rat: LD50 = 5045 mg/kg; Skin, rabbit: LD50
= 12800 mg/kg.
Carcinogenicity:
Isopropanol -
IARC: Group 3 carcinogen
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Fish: Fathead Minnow: >1000 ppm; 96h; LC50Daphnia: >1000 ppm; 96h;
LC50Fish: Gold orfe: 8970-9280 ppm; 48h; LC50IPA has a high
biochemical oxygen demand and a potential to cause oxygen depletion
in aqueous systems, a low potential to affect aquatic organisms, a
low potential to affect secondary waste treatment microbial
metabolism, a low potential to affect the germination of some plants,
a high potential to biodegrade (low persistence) with unacclimated
microorganisms from activated sludge.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: ISOPROPANOL
Hazard Class: 3
UN Number: 1219
Packing Group: II
IMO
Shipping Name: ISOPROPANOL
Hazard Class: 3
UN Number: 1219
Packing Group: II
RID/ADR
Shipping Name: ISOPROPANOL
Dangerous Goods Code: 3
UN Number: 1219
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI F
Risk Phrases:
R 11 Highly flammable.
R 36 Irritating to eyes.
R 67 Vapors may cause drowsiness and dizziness.
Safety Phrases:
S 7 Keep container tightly closed.
S 16 Keep away from sources of ignition - No
smoking.
S 24/25 Avoid contact with skin and eyes.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
WGK (Water Danger/Protection)
CAS# 67-63-0: 1
United Kingdom Occupational Exposure Limits
CAS# 67-63-0: OES-United Kingdom, TWA 400 ppm TWA; 999 mg/m3 TWA
CAS# 67-63-0: OES-United Kingdom, STEL 500 ppm STEL; 1250 mg/m3 STEL
Canada
CAS# 67-63-0 is listed on Canada's DSL List.
CAS# 67-63-0 is listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 67-63-0: OEL-AUSTRALIA:TWA 400 ppm (980 mg/m3);STEL 500 ppm (1225
mg/m3)
OEL-BELGIUM:TWA 400 ppm (985 mg/m3);STEL 500 ppm (1230 mg/m3)
OEL-DENMARK:TWA 200 ppm (490 mg/m3);Skin
OEL-FRANCE:STEL 400 ppm (980 mg/m3)
OEL-GERMANY:TWA 400 ppm (980 mg/m3)
OEL-JAPAN:STEL 400 ppm (980 mg/m3)
OEL-THE NETHERLANDS:TWA 400 ppm (980 mg/m3);Skin
OEL-THE PHILIPPINES:TWA 400 ppm (980 mg/m3)
OEL-RUSSIA:STEL 400 ppm (10 mg/m3)
OEL-SWEDEN:TWA 150 ppm (350 mg/m3);STEL 250 ppm (600 mg/m3)
OEL-SWITZERLAND:TWA 400 ppm (980 mg/m3);STEL 800 ppm
OEL-TURKEY:TWA 200 ppm (500 mg/m3)
OEL-UNITED KINGDOM:TWA 400 ppm (980 mg/m3);STEL 500 ppm;Skin
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
US FEDERAL
TSCA
CAS# 67-63-0 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 1/18/1999 Revision #9 Date: 10/12/2001
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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