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MSDS 
:
 Riboflavin
CAS 
:
 83-88-5
SYNONYMS 
:
 Lactoflavine; 6,7-Dimethyl-9-D-ribitylisoalloxazine; Isoalloxazine,     7,8-dimethyl-10-D-ribityl-;Isoalloxazine,     7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-; Vitamin B2;     Vitamin G
**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 83-88-5 |Riboflavin | ca.100 | 201-507-1 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

**** SECTION 3 - HAZARDS IDENTIFICATION ****

EMERGENCY OVERVIEW
Light sensitive.

Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation. May cause skin discoloration.
Ingestion:
Ingestion of large amounts may cause gastrointestinal irritation.
Inhalation:
Causes respiratory tract irritation. Can produce delayed pulmonary
edema.
Chronic:
Effects may be delayed. Laboratory experiments have resulted in
mutagenic effects.

**** SECTION 4 - FIRST AID MEASURES ****

Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical
aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

**** SECTION 5 - FIRE FIGHTING MEASURES ****

General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. This
material in sufficient quantity and reduced particle size is capable
of creating a dust explosion.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

**** SECTION 7 - HANDLING and STORAGE ****

Handling:
Remove contaminated clothing and wash before reuse. Minimize dust
generation and accumulation. Avoid contact with eyes, skin, and
clothing. Keep container tightly closed. Avoid ingestion and
inhalation. Use with adequate ventilation. Store protected from
light. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances. Store
protected from light.

**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 83-88-5:

Russia: 1 mg/m3 TWA

Personal Protective Equipment

Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.

**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State: Crystals
Color: Yellow powder or orange-yellow crystals
Odor: slight odor
pH: 6 (neutral)
Vapor Pressure: Negligible.
Viscosity: Not applicable.
Boiling Point: Not available.
Freezing/Melting Point: 290 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: 290 deg C
Solubility in water: Soluble.
Specific Gravity/Density: Not available.
Molecular Formula: C17H2ON4O6
Molecular Weight: 374.0366

**** SECTION 10 - STABILITY AND REACTIVITY ****

Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions. Light sensitive.
Conditions to Avoid:
Incompatible materials, light, dust generation, moisture, excess
heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, reducing agents, bases, calcium, metallic
salts.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of phosphorus, irritating
and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.

**** SECTION 11 - TOXICOLOGICAL INFORMATION ****

RTECS#:
CAS# 83-88-5: VJ1400000
LD50/LC50:
CAS# 83-88-5: Oral, rat: LD50 = >10 gm/kg.
Carcinogenicity:
Riboflavin -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

**** SECTION 12 - ECOLOGICAL INFORMATION ****



**** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Products which are considered hazardous for supply are classified as Special
Waste and the disposal of such chemicals is covered by regulations which may
vary according to location. Contact a specialist disposal company or the local
waste regulator for advice. Empty containers must be decontaminated before
returning for recycling.

**** SECTION 14 - TRANSPORT INFORMATION ****

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

**** SECTION 15 - REGULATORY INFORMATION ****

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 83-88-5: No information available.
Canada
CAS# 83-88-5 is listed on Canada's DSL List.
CAS# 83-88-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 83-88-5 is listed on the TSCA inventory.

**** SECTION 16 - ADDITIONAL INFORMATION ****

MSDS Creation Date: 7/16/1999 Revision #2 Date: 3/18/2003

The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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