* Bromeosin
* C.I. 45380:2
* C.I. Solvent Red 43
* D and C Red No. 21
* Eosin acid
* Eosine acid
* Japan Red No. 223
* Red No. 223
* Solvent Red 43
* Spiro(isobenzofuran-1(3H),9'-(9H)-xanthen)-3-one,
2',4',5',7'-tetrabromo-3',6'-dihydroxy-
* 2',4',5',7'-Tetrabromofluorescein
*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : LM5800000
CHEMICAL NAME : Fluorescein, 2',4',5',7'-tetrabromo-
CAS REGISTRY NUMBER : 15086-94-9
BEILSTEIN REFERENCE NO. : 0063410
REFERENCE : 4-19-00-02917 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 9
MOLECULAR FORMULA : C20-H8-Br4-O5
MOLECULAR WEIGHT : 647.92
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* Bromeosin
* C.I. 45380:2
* C.I. Solvent Red 43
* D and C Red No. 21
* Eosin acid
* Eosine acid
* Japan Red No. 223
* Red No. 223
* Solvent Red 43
* Spiro(isobenzofuran-1(3H),9'-(9H)-xanthen)-3-one,
2',4',5',7'-tetrabromo-3',6'-dihydroxy-
* 2',4',5',7'-Tetrabromofluorescein
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Amphibian - frog
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
** MUTATION DATA **
TYPE OF TEST : DNA repair
TEST SYSTEM : Bacteria - Bacillus subtilis
DOSE/DURATION : 2 mg/disc
REFERENCE :
TRENAF Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo
Metropolitan Research Laboratory of Public Health. (Tokyo-toritsu Eisei
Kenkyusho, 24-1, 3-chome, Hyakunin-cho, Shin-juku-ku, Tokyo 160, Japan) V.1-
1949/50- Volume(issue)/page/year: 27,153,1976
*** REVIEWS ***
IARC Cancer Review:Animal Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 15,183,1977
IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 15,183,1977
IARC Cancer Review:Group 3
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,56,1987
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - T0363
No. of Facilities: 347 (estimated)
No. of Industries: 2
No. of Occupations: 5
No. of Employees: 7340 (estimated)
No. of Female Employees: 1584 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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