*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : LM6290000
CHEMICAL NAME : Fluoride
CAS REGISTRY NUMBER : 16984-48-8
LAST UPDATED : 199710
DATA ITEMS CITED : 32
MOLECULAR FORMULA : F
MOLECULAR WEIGHT : 19.00
COMPOUND DESCRIPTOR : Mutagen
Reproductive Effector
Human
SYNONYMS/TRADE NAMES :
* Fluoride(1-)
* Fluoride ion
* Fluoride ion(1-)
* Perfluoride
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human
DOSE/DURATION : 3 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
Liver - other changes
REFERENCE :
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 27,237,1982
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human
DOSE/DURATION : 50 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
Liver - other changes
Kidney, Ureter, Bladder - other changes
REFERENCE :
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 27,237,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 22800 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MIVRA6 Microvascular Research. (Academic Press, Inc., 1 E. First St.,
Duluth, MN 55802) V.1- 1968- Volume(issue)/page/year: 8,320,1974
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 764 mg/kg/43W-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes
Musculoskeletal - other changes
Nutritional and Gross Metabolic - changes in metals, not otherwise specified
REFERENCE :
BECTA6 Bulletin of Environmental Contamination and Toxicology.
(Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
07094) V.1- 1966- Volume(issue)/page/year: 26,428,1981
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 90 mg/kg
SEX/DURATION : female 10 week(s) pre-mating
female 1-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - behavioral
REFERENCE :
BCTKAG Bromatologia i Chemia Toksykologiczna. (Ars Polona, POB 1001, 00-068
Warsaw 1, Poland) V.4- 1971- Volume(issue)/page/year: 22,158,1989
** MUTATION DATA **
TYPE OF TEST : DNA inhibition
TEST SYSTEM : Rodent - mouse Fibroblast
DOSE/DURATION : 1300 umol/L
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59,
1945-86. For publisher information, see PHTOEH Volume(issue)/page/year:
45,96,1979
*** U.S. STANDARDS AND REGULATIONS ***
MSHA STANDARD-air:TWA 2.5 mg/m3
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
3,116,1971
OSHA PEL (Gen Indu):8H TWA 2.5 mg(F)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994
OSHA PEL (Construc):8H TWA 2.5 mg(F)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994
OSHA PEL (Shipyard):8H TWA 2.5 mg(F)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993
OSHA PEL (Fed Cont):8H TWA 2.5 mg(F)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 2.5 mg(F)/m3 JAN 1993
OEL-BELGIUM:TWA 2.5 mg(F)/m3 JAN 1993
OEL-DENMARK:TWA 2.5 mg(F)/m3 JAN 1993
OEL-FINLAND:TWA 2.5 mg(F)/m3 JAN 1993
OEL-FRANCE:TWA 2.5 mg(F)/m3 JAN 1993
OEL-GERMANY:TWA 2.5 mg(F)/m3 JAN 1993
OEL-HUNGARY:TWA 1 mg(F)/m3;STEL 2 mg(F)/m3 JAN 1993
OEL-THE NETHERLANDS:TWA 2.5 mg(F)/m3 JAN 1993
OEL-THE PHILIPPINES:TWA 2.5 mg(F)/m3 JAN 1993
OEL-POLAND:TWA 1 mg(F)/m3 JAN 1993
OEL-SWEDEN:TWA 2 mg(F)/m3 JAN 1993
OEL-SWITZERLAND:TWA 1.8 ppm (1.5 mg(F)/m3);STEL 9.0 ppm JAN 1993
OEL-THAILAND:TWA 2.5 mg(F)/m3 JAN 1993
OEL-TURKEY:TWA 2.5 mg(F)/m3 JAN 1993
OEL-UNITED KINGDOM:TWA 2.5 mg(F)/m3 JAN 1993
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO FLUORIDES, INORGANIC-air:10H TWA 2.5 mg(F)/m3
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
*** STATUS IN U.S. ***
EPA GENETOX PROGRAM 1988, Negative: In vivo cytogenetics-nonhuman lymphocyte
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
NIOSH Analytical Method, 1994: Fluoride in urine, 8308
NIOSH Analytical Method, 1994: Fluoride aerosol and gas, by IC, 7906; by ISE
7902
*** END OF RECORD ***
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| ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| | NAME | CAS |
|
9H-Fluoren-9-one, 2,3,6,7-tetrachloro-
| 75803-56-4 |
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9H-Fluoren-9-one, 1,2,3,4-tetrahydro-
| 634-19-5 |
|
9H-Fluoren-9-one, 2,4,5,7-tetranitro-
| 746-53-2 |
|
Fluoren-9-one, O-(3,4,5-trimethoxybenzoyl)oxime
| 1866-76-8 |
|
Ethylenediamine,N-(alpha-(p-chlorophenyl)benzyl)-N,N',N'-trimethyl-,dioxalate
| 23892-35-5 |
|
Fluoren-9-one, 2,4,7-trinitro-
| 129-79-3 |
|
Fluoreno(9,1-gh)quinoline
| 206-00-8 |
|
Fluoren-9-yl hydroperoxide, 9-methyl-
| 18774-09-9 |
|
Fluorescein
| 2321-07-5 |
|
Fluorescein, 4',5'-dibromo-
| 596-03-2 |
|
Fluorescein, 4',5'-dibromo-, disodium salt (8CI)
| 4372-02-5 |
|
Fluorescein, 2',7'-dibromo-4'-(hydroxymercurio)-,disodium salt
| 129-16-8 |
|
Fluorescein, 4,7-dichloro-2',4',5',7'-tetrabromo-,dipotassium salt
| 6441-77-6 |
|
Fluorescein, disodium salt
| 518-47-8 |
|
Fluorescein, 2',4',5',7'-tetrabromo-
| 15086-94-9 |
|
Ethylenediamine,N-(alpha-(p-chlorophenyl)benzyl)-N'-(2,6-xylyl)-,maleate
| 23953-35-7 |
|
Fluorescein, 2',4',5',7'-tetrabromo-, disodium salt
| 17372-87-1 |
|
Fluorescein,2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-
| 2134-15-8 |
|
Fluorescein,2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-, disodiumsalt
| 18472-87-2 |
|
Fluorescein,4,5,6,7-tetrachloro-2',4',5',7'-tetraiodo-, disodiumsalt
| 632-69-9 |
|
Fluorescein, 2',4',5',7'-tetraiodo-
| 15905-32-5 |
|
Fluorescein, 2',4',5',7'-tetraiodo-, disodium salt
| 16423-68-0 |
|
Fluoride
| 16984-48-8 |
|
Fluorine
| 7782-41-4 |
|
Fluorocarbon elastomer, pyrolysateSUBSTANCE DEFINITION :Pyrolysis point is 550 degrees CREFERENCE :SAIGBL Sangyo Igaku. Japanese Journal of Industrial Health. (Nippon SangyoEisei Igakkai, Kosu Eisei Bldg., 1-29-8, Shinjuku, Shinjuku-ku, Tokyo 160,Japan) V.1- 1959- Volume(issue)/page/year: 17,289,1975
| 7782-41-4 |
|
Fluorocarbon emulsions
| 7782-41-4 |
|
Ethylenediamine, N-(p-cumenyl)-N',N'-diethyl-
| 7782-41-4 |
|
Fluorochlorocarbon liquid
| 7782-41-4 |
|
Fluorocurine
| 6879-92-1 |
|
Fluorosulfuric acid
| 7789-21-1 |
|
Fluorosulfuric acid, methyl ester
| 421-20-5 |
|
Fluosol-DA
| 75216-20-5 |
|
Fluosol-DA 20%
| 75216-20-5 |
|
Fluotantalate
| 75216-20-5 |
|
Fluvomycin
| 1391-62-4 |
|
Flux oilSUBSTANCE DEFINITION :A complex mixture of alkyldiarylethanesREFERENCE :EPASR* United States Environmental Protection Agency, Office of Pesticidesand Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW,Washington, DC 20460) History unknown. Volume(issue)/page/year:8EHQ-0890-0984
| 1391-62-4 |
|
Fly ash, nickel-enriched
| 1391-62-4 |
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